Matches 1 - 50 out of 349 1 2 3 4 5 6 7 >


Match Document Document Title
US20140162903 Metabolite Biomarkers For Forecasting The Outcome of Preoperative Chemotherapy For Breast Cancer Treatment  
The present disclosure relates to a panel of metabolite species that is useful for forecasting the outcome of preoperative chemotherapy for the treatment of breast cancer, including methods for...
US20130261024 System for Identifying Connections Between Perturbagens and Genes Associated with a Skin Hyperpigmentation Condition  
A system for identifying connections between perturbagens and genes associated with a skin hyperpigmentation condition. The system includes a computer readable medium having a plurality of...
US20110130297 QUANTUM DOT-SENSORY ARRAY FOR BIOLOGICAL RECOGNITION  
The present invention provides a quantum dot-based biomolecule sensor array capable of differentiating the strain of a variety of biological molecules including bacteria, spores, fungi, viruses,...
US20140162905 EVAPORATIVE EDGE LITHOGRAPHY OF A LIPOSOMAL DRUG MICROARRAY FOR CELL MIGRATION ASSAYS  
Lipid multilayer structures are formed by evaporating a solvent from each of a plurality of lipid solutions thereby form the lipid multilayer structures. Each lipid solution comprises the solvent...
US20150133331 METABOLITE BIOMARKERS FOR THE DETECTION OF LIVER CANCER  
Methods for the detection and screening of hepatocellular carcinoma (HCC) patients and for the monitoring of HCC treatment using a panel or panels of small molecule metabolite biomarkers are...
US20120087862 ORGAN-SPECIFIC PROTEINS AND METHODS OF THEIR USE  
The present invention relates generally to methods for identifying and using organ-specific proteins and transcripts. The present invention further provides compositions comprising organ-specific...
US20120142542 Metabolite Biomarkers for the Detection of Esophageal Cancer Using NMR  
Methods for the detection and screening of esophageal adenocarcinoma (EAC) patients and for the monitoring of EAC treatment using a panel or panels of small molecule metabolite biomarkers are...
US20140274778 METHODS AND SYSTEMS FOR MULTIPLEX ASSAYS  
Disclosed herein are compositions comprising beads with unique identifiers for storing information about a multiplex assay as well as methods for using the same in multiplex chemical and...
US20140148349 Metabolite Biomarkers for the Detection of Esophageal Cancer Using NMR  
Methods for the detection and screening of esophageal adenocarcinoma (EAC) patients and for the monitoring of EAC treatment using a panel or panels of small molecule metabolite biomarkers are...
US20150140123 Protein expression analyses for identifying genotoxic compounds  
The invention relates to a method for screening compounds with (pro-)genotoxic activity by providing a system being capable of expressing a panel of defined proteins, incubating at least a portion...
US20150152509 METHODS AND NUCLEIC ACIDS FOR ANALYSIS OF BLADDER CELL PROLIFERATIVE DISORDERS  
The invention provides methods, nucleic acids and kits for detecting bladder carcinoma. The invention discloses genomic sequences the methylation patterns of which have utility for the improved...
US20120108463 COMPOSITIONS AND METHODS FOR MEMBRANE PROTEIN DETERGENT STABILITY SCREEN  
The invention provides methods to assess protein stability and to obtain sizing information. In one aspect, the screen comprises a 94 detergent panel and a series of MWCO filtered microplates. A...
US20150153331 METABOLOMICS IN PNEUMONIA AND SEPSIS  
The present invention describes a global metabolomic profile of patients with community acquired pneumonia (CAP) and sepsis. The metabolomic profile of endogenous small molecules blood was...
US20120329661 Isotope Labeling-Assisted Quantification (iLAQ) of Biological Compounds  
The present invention relates to a plurality of isotopically labeled compounds (“tag isotopomers”) and individual labeled compounds, which are useful for labeling samples of analytes, such as...
US20110212860 Modulation of Bacterial Quorum Sensing With Synthetic Ligands  
The present invention provides compounds and methods for modulation of the quorum sensing of bacteria. In an embodiment, the compounds of the present invention are able to act as replacements for...
US20130040862 MULTI-PILLAR STRUCTURE FOR MOLECULAR ANALYSIS  
A multi-pillar structure for molecular analysis is provided. The structure comprises at least two nanopoles, each nanopole attached at one end to a substrate and freely movable along its length....
US20140051602 DETECTING ANALYTES USING LIPID MULTILAYER GRATINGS WITH ION CHANNELS  
A method comprising the following step: determining that one or more analytes are present in a fluid to which an array of lipid multilayer gratings has been exposed based on scattered light...
US20110160074 Capture Ligand Controls, Blocking Probes, Masking Probes and Methods of Using the Same  
The invention, depending on aspect and embodiment, relates to capture probe controls, and capture and signal probe configurations and combinations of configurations that can facilitate accurate...
US20140221236 METABOLOMIC MARKERS FOR PRETERM BIRTH  
Panels, kits, and methods for diagnosing or predicting the likelihood of occurrence of preterm birth (PTB) in a subject are disclosed. An exemplary panel includes at least one of a first marker...
US20130116140 METHODS AND MATERIALS FOR DETERMINING THE EFFICACY OF PROSTATE CANCER THERAPIES  
Methods for monitoring, and determining the efficacy of, a treatment for prostate cancer in a subject are provided, such methods including detecting the levels of expression of multiple...
US20110059857 MARKERS OF ACUTE KIDNEY FAILURE  
The present invention relates to the method of determining the risk of acute kidney injury comprising determining the amount of a marker selected from VCAN, NRP1, CCL2, CCL19, COL3A1, GZMM or any...
US20150099668 METABOLITE BIOMARKERS FOR STAGING COLORECTAL CANCER  
This document provides methods and materials for assessing metabolites in a sample from a mammal (e.g., human) for determining the nature and extent of colorectal cancer (CRC) metastasis. For...
US20150018240 THERANOSTICS PLATFORM AND METHODS OF USE  
Theranostics platforms for identifying drugs and nutraceuticals for treatment of rare disease are described. The platforms comprise (a) a cell-phenotype image-enhancing instrument; (b) a...
US20140073581 Hybrid Cyclic Libraries and Screens Thereof  
Provided are novel types of hybrid cyclic libraries that contain a known protein binding domain of a natural product. Also provided are synthetic methods to make such libraries and methods for the...
US20110269632 Detection of Cancer through Breath Comprising a Sensor Array Comprising Capped Conductive Nanoparticles  
Sensor array for detecting biomarkers for cancer in breath samples. The sensor array is based on 2D films or 3D assemblies of conductive nanoparticles capped with an organic coating wherein the...
US20110202281 ADAPTIVE BIOCHEMICAL SIGNATURES  
The present invention is related to methods of generating adaptive biochemical signatures in live cells and the use of said signatures to identify diagnostic and therapeutic modalities for human...
US20110082053 Molecular Rectifiers Comprising Diamondoids  
Provided is a molecular rectifier comprised of a diamondoid molecule and an electron acceptor attached to the diamondoid molecule. The electron acceptor is generally an electron accepting aromatic...
US20110301062 RELIABLE FLUORESCENCE CORRECTION METHOD FOR TWO-COLOR MEASUREMENT FLUORESCENCE SYSTEM  
Methods and devices use in two-color measurement systems. The methods and devices include methods of making corrections, methods of calculating correction factors, fluorescence scanners, and...
US20100202672 Protein Layers And Their Use In Electron Microscopy  
Protein layers (1) repeating regularly in two dimensions comprise protein protomers (2) which each comprise at least two monomers (5), (6) genetically fused together. The monomers (5), (6) are...
US20110306668 CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID  
A process for synthesizing and screening solution phase derived libraries of fenbufen and ethacrynic acid is provided in the present invention. Compounds in the present invention having...
US20150250808 TREATMENT OF AUTOPHAGY-BASED DISORDERS AND RELATED PHARMACEUTICAL COMPOSITIONS, DIAGNOSTIC AND SCREENING ASSAYS AND KITS  
In one embodiment, the invention provides a method of treating a subject suffering from a Mycobacterium infection by administering to the subject a therapeutically-effective amount of a...
US20100304980 PLANAR LIPID BILAYER ARRAY FORMED BY MICROFLUIDIC TECHNIQUE AND METHOD OF ANALYSIS USING PLANAR LIPID BILAYER  
There is provided a planar lipid bilayer array formed by microfluidic technique and a method of analysis using the planar lipid bilayers, providing the advantages such as portability, decreased...
US20150065389 MULTI-WELL MICROPATTERNING BY ABLATION  
The present invention is drawn to the generation of micropatterns of biomolecules and cells on standard laboratory materials through selective ablation of a physisorbed biomolecule with oxygen...
US20130196872 PATHOGEN DETECTION  
Pathogens are detected through the use of mutation-resistant ligands.
US20090203536 Assay supports comprising a peg support, said support attached from a peg solution in cloud point (theta solvent) conditions  
Assay supports, such as microarrays and similar devices, and methods of use and manufacture thereof, are described. The assay support is capable of assaying binding and/or activity of a bioactive...
US20110245105 Methods and Kits for Direct Detection and Susceptibility Profiling of Beta-Lactam Resistant Bacteria  
The present invention relates to a convenient, flexible and cost-efficient technology for detection and resistance-profiling of bacteria, enabling effective, evidence-based treatment of...
US20140256573 RAPID QUANTIFICATION OF BIOMOLECULES IN A SELECTIVELY FUNCTIONALIZED NANOFLUIDIC BIOSENSOR AND METHOD THEREOF  
A method and device for the rapid quantification of biomolecules (320) present in a nanochannel (210) is claimed. In particular, the present invention relates to a novel concept of liquid...
US20110172124 COMPOSITIONS AND PROCESSES FOR IMPROVED MASS SPECTROMETRY ANALYSIS  
The invention provides a novel additive for improved analysis by mass spectrometry. More specifically, ascorbic acid has been found to reduce or eliminate the presence of adducts commonly present...
US20110263688 COFERONS AND METHODS OF MAKING AND USING THEM  
A monomer useful in prepaπng therapeutic compounds includes a diversity element which potentially binds to a target molecule with a dissociation constant of less than 300 11 M and a linker element...
US20110009292 ATTACHMENT OF MOLECULES TO SURFACES  
The present invention relates to methods, reagents, and substrates that can be used for, for example, immobilizing biomolecules, such as nucleic acids and proteins. In an embodiment, the present...
US20130196879 ASSAY SYSTEM  
The invention provides a method of forming a plurality of re-constitutable doses of at least one drug in a plurality of wells, the method including the steps of (i) placing a known amount of said...
US20150080265 TERPENE-BASED COMPOSITIONS, PROCESSES, METHODOLOGIES FOR CREATION AND PRODUCTS THEREBY  
Compositions which are fragrant and contain at least a member set culled from a library of compositions, each being comprised of sub-combinations of selected terpenes. Fragrances that mimic that...
US20110281764 SCREENING ASSAYS AND METHODS  
Screening assays and methods of performing such assays are provided. In certain examples, the assays and methods may be designed to determine whether or not two or more species can associate with...
US20110046081 CLASSICAL CANNABINOID METABOLITES AND METHODS OF USE THEREOF  
The present invention encompasses classical cannabinoid metabolites and uses thereof.
US20110245088 AMIDE-BASED SOLUTION-PHASE DERIVED LIBRARY AND METHOD FOR SCREENING THEREOF  
An amide-based library is disclosed in the invention which is prepared via amide bond formation coupling an amine with a carboxylic acid. Also, a method using said library for screening a drug...
US20140349885 ENHANCEMENT OF SENSITIVITY AND SPECIFICITY OF KETOSTEROIDS AND KETO OR ALDEHYDE CONTAINING ANALYTES  
A method, a labeling reagent, sets of labeling reagents, and labeling techniques are provided for the relative quantitation, absolute quantitation, or both, of ketone or aldehyde compounds...
US20130202601 ASSAYS, METHODS AND KITS FOR PREDICTING RENAL DISEASE AND PERSONALIZED TREATMENT STRATEGIES  
Assays, methods and kits for predicting a subject's (e.g., human) risk of primary glomerulopathy, secondary glomerulopathy or recurrence (e.g., post-transplant recurrence) of any glomerular...
US20100298168 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions  
Capture compounds and collections thereof and methods using the compounds for the analysis of biomolecules are provided. In particular, collections, compounds and methods are provided for...
US20120122735 COMPOSITION, DEVICE AND ASSOCIATED METHOD  
A composition includes a first probe, a first initiator component bonded to the first probe, a second probe, and a second initiator component bonded to the second probe. The first probe and the...
US20150057185 REACTION-BASED FLUORESCENT PROBE FOR SELECTIVE DETECTION OF CARBON MONOXIDE USING METAL-MEDIATED CARBONYLATION  
Carbon monoxide (CO) is a member of the gasotransmitter family that includes NO and H2S and is implicated in a variety of pathological and physiological conditions. Whereas exogenous therapeutic...

Matches 1 - 50 out of 349 1 2 3 4 5 6 7 >