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US20150226722 Optical Trace Chemical Detection for Analysis of Latent Prints  
A method for optical analysis of otherwise invisible latent prints on a wide variety of surfaces and trace chemicals contained within the oils of a print. The invention provides the capability to...
US20150168419 PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT  
A method of predicting a SGA infant in a patient at a pre-symptomatic gestational stage is described. The method comprises a step of assaying a biological sample from the patient for an abundance...
US20130184173 BIOMARKERS FOR MULTIPLE SCLEROSIS  
Biomarkers that can be used for the diagnosis and prognosis of multiple sclerosis in pediatric patients presenting with clinically isolated syndrome or acquired demyelination syndrome are described.
US20150099664 PROTEIN BIOMARKERS AND THERAPEUTIC TARGETS FOR AUTOIMMUNE AND ALLOIMMUNE DISEASES  
A method for characterizing the risk a subject will develop an autoimmune and/or alloimmune disease following tissue transplant includes obtaining a biological sample from the subject, wherein the...
US20140162903 Metabolite Biomarkers For Forecasting The Outcome of Preoperative Chemotherapy For Breast Cancer Treatment  
The present disclosure relates to a panel of metabolite species that is useful for forecasting the outcome of preoperative chemotherapy for the treatment of breast cancer, including methods for...
US20150126403 METHOD OF IDENTIFYING PROTEINS IN HUMAN SERUM INDICATIVE OF PATHOLOGIES OF HUMAN LUNG TISSUES  
A method of identifying proteins present in human serum which are differentially expressed between normal individuals and patients known to have non-small cell lung cancers and asthma, as...
US20130157891 ORGAN SPECIFIC DIAGNOSTIC PANELS AND METHODS FOR IDENTIFICATION OF ORGAN SPECIFIC PANEL PROTEINS  
The present application provides novel compositions, methods, and assays for use in identification of appropriate diagnostic markers in blood. These compositions, methods, and assays are capable...
US20110136692 PROTEIN MICROARRAYS FOR MASS SPECTROMETRY AND METHODS OF USE THEREFOR  
The present invention relates to the use of mass spectrometry to analyze arrays. The present invention provides methods for characterizing solutions comprising one or more proteins using arrays...
US20120077707 MICROWELLS WITH MRI READABLE INDICIA  
A microwell including a plurality of MRI-readable indicia. The indicia indicate the identification or location of at least one predefined well or a plurality of wells. The indicia are selected...
US20120004127 Gene expression markers for colorectal cancer prognosis  
One example embodiment includes a method of preparing a personalized genomics profile for a patient with colorectal cancer. The method includes assaying an expression level of an RNA transcript in...
US20150133331 METABOLITE BIOMARKERS FOR THE DETECTION OF LIVER CANCER  
Methods for the detection and screening of hepatocellular carcinoma (HCC) patients and for the monitoring of HCC treatment using a panel or panels of small molecule metabolite biomarkers are...
US20140106981 Organ-Specific Proteins and Methods of Their Use  
The present invention relates generally to methods for identifying and using organ-specific proteins and transcripts. The present invention further provides compositions comprising organ-specific...
US20130045873 METHODS FOR IDENTIFYING AND USING ORGAN-SPECIFIC PROTEINS IN BLOOD  
The present invention relates generally to methods for identifying organ-specific secreted proteins and for identifying organ-specific molecular blood fingerprints therefrom. As such, the present...
US20150126402 Method for Quantifying Proteins and Isoforms Thereof  
A method for quantifying metallothionein protein isomers is described herein. Such metallothionein isomer protein quantification is useful for detecting and monitoring disease. As illustrated...
US20150219665 ANALYSIS OF SALIVA PROTEOME FOR BIOMARKERS OF GINGIVITIS AND PERIODONTITIS USING FT-ICR-MS/MS  
Methods for diagnosing the status of periodontitis disease includes selecting a set of protein biomarkers including one or more biomarkers which have been shown to vary in abundance at particular...
US20150192597 BIOMARKER FOR HUMAN PROSTATE CANCER  
A method of diagnosing the presence of cancer in a subject without the need for a biopsy is provided. The method comprises obtaining a bio-sample from the subject and then extracting lipids from...
US20150203912 PROTEIN DETECTION USING FET  
Accordingly, in some embodiments methods for detecting an analyte or analytes in one or more sample(s) are provided. The methods encompass providing a solid support with an addressable marker and...
US20140323352 Means and Methods for Diagnosing Pancreatic Cancer in a Subject  
The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing pancreatic cancer in a subject, a method for identifying...
US20110294700 HIGH-THROUGHPUT QUANTITATION OF CROP SEED PROTEINS  
The invention provides a high-throughput method for quantitating plant seed proteins, e.g. seed allergens. Such method involves obtaining a protein sample from the seed; analyzing the sample using...
US20150133343 POLYPEPTIDE MARKERS FOR THE DIAGNOSIS OF PROSTATE CANCER  
A method for the diagnosis of prostate cancer, comprising the step of determining the presence or absence of at least three polypeptide markers in a sample, wherein the polypeptide marker is...
US20140228229 Methods for Identifying and Monitoring Drug Side Effects  
The present invention relates generally to methods for identifying drug side effects by detecting perturbations in organ-specific molecular blood fingerprints. The invention further relates to...
US20150087728 COMPOSITIONS, METHODS AND KITS FOR DIAGNOSIS OF LUNG CANCER  
Methods are provided for identifying biomarker proteins that exhibit differential expression in subjects with a first lung condition versus healthy subjects or subjects with a second lung...
US20150153331 METABOLOMICS IN PNEUMONIA AND SEPSIS  
The present invention describes a global metabolomic profile of patients with community acquired pneumonia (CAP) and sepsis. The metabolomic profile of endogenous small molecules blood was...
US20110177974 NEURAL PROTEINS AS BIOMARKERS FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS  
The present invention identities biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree...
US20150198612 Isotopic Labelling of Proteins  
The present invention provides methods for enhancing the synthesis of isotope labelled native proteins in specific biological pathways for the purpose of protein quantification and qualification....
US20120220491 RETENTATE CHROMATOGRAPHY AND PROTEIN CHIP ARRAYS WITH APPLICATIONS IN BIOLOGY AND MEDICINE  
Analytes in a sample are resolved by retentate chromatography in a procedure involving adsorbing the analytes on a substrate under a plurality of different selectivity conditions, and detecting...
US20150110773 TARGETING THE GLUTAMINE TO PYRUVATE PATHWAY FOR TREATMENT OF ONCOGENIC KRAS-ASSOCIATED CANCER  
Methods and kits for GPP-targeting, e.g., for the treatment of oncogenic Kras-associated cancers, and methods for determining the efficacy of those methods are provided.
US20150080257 METHOD FOR EVALUATING URATE TRANSPORT-RELATED DISEASE FACTOR AND INFLAMMATION-RELATED DISEASE FACTOR  
A method and evaluation kit are provided, in which a high-capacity urate transporter is identified to assist in the early treatment and prevention of urate transport-related disease and...
US20150080248 METHODS FOR ISOLATING PROTEINS  
The invention generally relates to methods for isolating proteins. In certain aspects, methods of the invention involve preparing a plurality of sample preparations, each preparation including one...
US20130143755 Protein and Gene Biomarkers for Rejection of Organ Transplants  
Aspects of the present invention include methods for determining a transplant category of a subject having a transplant. Common mechanisms of rejection injury are uncovered across different tissue...
US20150024970 KIDNEY CELL CARCINOMA  
The process for the diagnosis of a renal cell carcinoma comprises the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sample, wherein said...
US20140364337 ABSOLUTE QUANTITATION OF PROTEINS AND PROTEIN MODIFICATIONS BY MASS SPECTROMETRY WITH MULTIPLEXED INTERNAL STANDARDS  
A method for absolute protein or peptide quantitation by mass spectroscopy. A sample containing a protein or peptide of interest is prepared for mass spectroscopy analysis. The sample is subjected...
US20120040842 Gene Expression Markers for Prediction of Patient Response to Chemotherapy  
The present invention relates to gene sets useful in assessing prognosis and/or predicting the response of cancer, e.g. colorectal cancer to chemotherapy. In addition, the invention relates to a...
US20140249049 USE OF CD5 ANTIGEN-LIKE AS A BIOMARKER FOR DIABETIC NEPHROPATHY  
Biomarkers for pre-Diabetes, Diabetes and/or a Diabetes related conditions, and methods of their use, including the biomarkers in Tables 1 and 2 such as peroxiredoxin-2, complement C1q...
US20110166040 COMPOSITIONS FOR USE IN IDENTIFICATION OF STRAINS OF E. COLI O157:H7  
The present invention relates generally to strain typing of Escherichia coli O157:H7, and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular...
US20140206563 BIOMARKERS FOR PSORIASIS  
A group of polypeptides that are modulated in a psoriatic sample as compared to a normal sample is provided. These polypeptides can be used as biomarkers for diagnosis and monitoring treatment of...
US20100313290 MULTIPLEX ANALYSIS OF STACKED TRANSGENIC PROTEIN  
The invention relates to methods for multiplex analysis of complex protein samples from plants using mass spectroscopy. In some embodiments, the disclosure concerns methods for maintaining a...
US20140038837 BIOMARKERS FOR THE DETECTION OF EARLY STAGE OVARIAN CANCER  
The present invention provides methods and compositions for detecting early stage ovarian cancer in a patient. Also, methods for evaluating the ovarian cancer state of a patient are described...
US20150185220 CANCER CLASSIFICATION AND METHODS OF USE  
The present invention relates to methods of classifying cancer cells based on the presence, absence or level of tyrosine kinase or a phophorylated tyrosine kinase. The present invention also...
US20140051602 DETECTING ANALYTES USING LIPID MULTILAYER GRATINGS WITH ION CHANNELS  
A method comprising the following step: determining that one or more analytes are present in a fluid to which an array of lipid multilayer gratings has been exposed based on scattered light...
US20140178358 Means and Methods to Diagnose Liver Toxicity using Putrescine as Biomarker  
The present invention concerns means and methods for predicting the risk of a subject to suffer from liver damage. In particular, it pertains to a method for predicting the risk of a subject to...
US20150105293 CLINICAL DIAGNOSIS OF HEPATIC FIBROSIS USING A NOVEL PANEL OF LOW ABUNDANT HUMAN PLASMA PROTEIN BIOMARKERS  
The inventors have proposed a novel panel of human plasma protein biomarkers for diagnosing hepatic fibrosis and cirrhosis. Presently there is no reliable non-invasive way of assessing liver...
US20120065104 COMPOSITIONS AND METHODS FOR A MEMBRANE PROTEIN CRYSTALLIZATION SCREENING KIT  
The present invention comprises compositions and methods useful as a system for efficiently determining conditions that result in the formation of crystals of membrane proteins from solutions...
US20150018246 POLYPEPTIDE MARKER FOR DIAGNOSING AND ASSESSING VASCULAR DISEASES  
The invention relates to a method for diagnosing vascular diseases, comprising the step in which the presence, absence or amplitude of at least three polypeptide markers is determined in a urine...
US20120172255 ES-MS OF GLYCOPEPTIDES FOR ANALYSIS OF GLYCOSYLATION  
Herein is reported a method for the determination of the glycosylation of an immunoglobulin with electrospray mass spectrometry but without the need for a chromatographic purification step after...
US20150218553 Screening Polynucleotide Libraries For Variants That Encode Functional Proteins  
The present invention provides methods based on screening expressed polynucleotide libraries for soluble proteins.
US20140037647 MOLECULAR SUBTYPING, PROGNOSIS AND TREATMENT OF PROSTATE CANCER  
Disclosed herein are new prognostic molecular markers for prostate cancer. More specifically, the invention has identified that overexpression or amplification of at least one of AURKA or MYCN...
US20150065391 POLYPEPTIDE MARKERS FOR DIAGNOSIS AND ASSESSMENT OF HEART FAILURE  
Method for diagnosis of heart failure, comprising the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sample, the polypeptide markers...
US20140171341 MULTIPLEXED DIGITAL ASSAYS  
System, including methods and apparatus, for performing a multiplexed digital assay.
US20140235473 Diagnosis and/or Prognosis of Parkinson's Disease Dementia  
The present Invention provides a method for diagnosing and/or prognosing Parkinson's disease dementia (PDD) comprising the step of detecting O-glycosylation. in a protein comprising a Ser/Thr...