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US20120225486 DIAGNOSIS AND ASSESSMENT OF SKELETAL RELATED DISEASE USING CALCIUM 41  
A method of determining calcium metabolism in a patient comprises the steps of administering radioactive calcium isotope 41Ca to the patient, allowing a period of time to elapse sufficient for...
US20130116343 Salivary Protein Markers for Detection of Breast Cancer  
A method of diagnosing a patient's risk of breast cancer comprises measuring in a saliva sample from the patient a concentration of at least a first protein marker, wherein the first protein...
US20120088685 DIAGNOSIS OF NEUROPSYCHIATRIC AND BEHAVIOURAL DISORDERS  
This invention provides a method of identifying GAS infection as the cause of a neuropsychiatric or behavioural disorder in a patient, or of identifying a patient at risk of developing a...
US20130102082 PROTEIN CONCENTRATION ASSAY METHOD ANALYSIS TOOL AND ANALYZER  
Provided is a protein concentration assay method that uses a protein indicating reagent and that enables highly accurate assay. The protein concentration assay method includes: optically analyzing...
US20130090550 METHODS OF IDENTIFYING PATIENTS WITH OVARIAN EPITHELIAL NEOPLASMS BASED ON HIGH-RESOLUTION MASS SPECTROMETRY  
Methods for identifying patients with ovarian neoplasms are provided herein comprising performing an assay step of detecting a metabolite in a serum sample of a patient where the metabolite is...
US20110104669 METHOD TO PREDICT IRIS COLOR  
The invention comprises a method to predict iris color of a human from a nucleic acid/protein sample comprising assaying for one or more polymorphisms in the region 5′ proximal of the OCA2 gene up...
US20120009125 APOE4 AND APOJ BIOMARKER-BASED PREVENTION AND TREATMENT OF DEMENTIA  
Methods, kits, screens, assays, treatments and treatment regimes for treating a patient at risk for or suffering from dementia, and particularly Alzheimer's dementia which are based upon...
US20140011283 METHOD OF DETERMINING A CONCENTRATION OF NITRATE  
A method of determining a concentration of nitrate includes mixing an acid with a first mixture comprising an aldehyde, a chloride and at least one of a nitrate sample and distilled water so as to...
US20150185232 INNATE IMMUNE PROTEINS AS BIOMARKERS FOR CNS INJURY  
The present invention provides novel markers of the severity of a central nervous system injury, such as spinal cord injury or traumatic brain injury, in a patient. In particular, protein...
US20110021370 SALIVARY PROTEIN BIOMARKERS FOR HUMAN ORAL CANCER  
The present invention relates to the identification of novel oral cancer and periodontal disease biomarkers. Further, the present invention provides novel methods of diagnosing and for providing a...
US20150110897 Sperm Protein as a Detection Biomarker of Early Stage Ovarian Cancer  
This disclosure provides a method for determining if a patient is likely to, or not likely to, experience ovarian cancer utilizing SP17 as a biomarker. It also provides methods and therapies to...
US20130295679 PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT  
A method of predicting a SGA infant in a patient at a pre-symptomatic gestational stage is described. The method comprises a step of assaying a biological sample from the patient for an abundance...
US20110190149 NEOEPITOPE DETECTION OF DISEASE USING PROTEIN ARRAYS  
A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of...
US20140141992 NEOEPITOPE DETECTION OF DISEASE USING PROTEIN ARRAYS  
A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of...
US20120204276 METHODS RELATED TO A MUTATION IN COMPLEMENT FACTOR H-RELATED PROTEIN 5 IN PATIENTS WITH GLOMERULONEPHRITIS  
The invention relates to methods of regulating complement. In particular, the inventors have identified a relationship between a particular gene, CFHR5, and irregularities in complement...
US20120028835 SECERNIN-1 AS A MARKER FOR CANCER  
Disclosed is a method aiding in the assessment of cancer. It involves the use of the secernin-1 protein (SCRN1) as a universal marker of different cancer types. More specifically disclosed is a...
US20120046185 PANEL OF BIOMARKERS FOR OVARIAN CANCER  
The present invention provides a panel of protein-based biomarkers that are useful in diagnosing ovarian cancer in a subject. In particular, the panel of biomarkers of the invention are useful to...
US20150173685 TRIAGE SCORING SYSTEM  
The application discloses a method of determining the severity of symptoms in a patient comprising (i) producing a triage score, such as an early warning score (EWS) modified early warning score...
US20150023950 2,6-Diaminopyridine Compounds Suitable for Treating Diseases Associated with Amyloid or Amyloid-Like Proteins or for Treating or Preventing Ocular Diseases or Conditions Associated with a Pathological Abnormality/Change in the Tissue of the Visual System  
The present invention relates to 2,6-diaminopyridine compounds that can be employed in the treatment of a group of disorders and abnormalities associated with amyloid protein and of diseases or...
US20130066088 METHODS FOR OBTAINING HIGH-YIELDING OIL PALM PLANTS  
Methods are provided for obtaining a high-yielding oil palm plant, comprising determining the level of a protein in mesocarp tissue of a fruit of a parental oil palm plant, determining whether...
US20120214710 METHOD OF PREDICTING RESPONSE TO THALIDOMIDE IN MULTIPLE MYELOMA PATIENTS  
A method of predicting response to thalidomide, or thalidomide analogs, in an individual with cancer, especially cancers for which thalidomide has been implicated as a treatment, such as Multiple...
US20120045849 SYSTEM AND METHOD TO MEASURE DISSOCIATION CONSTANTS  
A system and method for determining the dissociation constant for a particular ligand is disclosed. In accordance with certain embodiments, the method creates a chemical denaturation curve of a...
US20140273239 AIR REMOVAL TEST STRIP  
An air removal test system for verifying adequate air removal during a sterilization cycle of a pre-vacuum type sterilizer includes specimen holder and a test strip. The test strip includes a...
US20140162891 METHODS AND MATERIALS FOR DETECTION, DIAGNOSIS AND MANAGEMENT OF OVARIAN CANCER  
The subject invention concerns methods using a panel of proteins to detect, diagnose, and monitor therapy during treatment of ovarian cancer in a female patient. The proteins were identified using...
US20140308676 CITRULLINATED PROTEINS: A POST-TRANSLATED MODIFICATION OF MYOCARDIAL PROTEINS AS MARKER OF PHYSIOLOGICAL AND PATHOLOGICAL DISEASE  
Disclosed herein are methods for diagnosing cardiovascular disease. The methods comprise detection of citrullinated proteins.
US20150099726 DRY POWDER INHALER  
This invention provides a dry powder inhaler comprising: a dry powder medicament comprising fluticasone propionate, salmeterol xinafoate and a lactose carrier; wherein, the delivered dose of...
US20140127731 Method And System For Detecting and Differentiating Cancer and Sepsis in Mammals Using Biomarkers  
The invention provides a method and system for developing and using diagnoses of cancer and sepsis in canine subjects using Thymidine kinase (TK), c-reactive protein (CRP), and C-type natriuretic...
US20140141415 NUCLEIC ACID ENCODING A SELF-ASSEMBLING SPLIT-FLUORESCENT PROTEIN SYSTEM  
The invention provides a protein labeling and detection system based on self-complementing fragments of fluorescent and chromophoric proteins. The system of the invention is exemplified with...
US20110250592 METHODS FOR DETERMINING A PATIENT'S SUSCEPTIBILITY OF CONTRACTING A NOSOCOMIAL INFECTION AND FOR ESTABLISHING A PROGNOSIS OF THE PROGRESSION OF SEPTIC SYNDROME  
A method for determining a patient's susceptibility of contracting a nosocomial infection that includes obtaining a biological sample from the patient and extracting biological material from the...
US20140294843 DIAGNOSIS AND TREATMENT OF COPD  
Provided is a method for diagnosing and/or staging COPD based on detection of one or more histone proteins. In some embodiments, the histone protein is an H3.3 protein comprising a...
US20150099664 PROTEIN BIOMARKERS AND THERAPEUTIC TARGETS FOR AUTOIMMUNE AND ALLOIMMUNE DISEASES  
A method for characterizing the risk a subject will develop an autoimmune and/or alloimmune disease following tissue transplant includes obtaining a biological sample from the subject, wherein the...
US20120019386 Wireless biosensor network for point of care preparedness for critical patients  
A biodegradable, bio-compatible material is described for use in wireless biosensors for point-of-care applications. The biosensor made from this biomaterial is capable of sensing environmental...
US20110059549 METHODS AND SYSTEMS FOR PRODUCING NANOLIPOPROTEIN PARTICLES  
Provided herein are methods and systems for the production of a nanolipoprotein particle (NLP) that includes a scaffold protein a membrane forming lipid and optionally a target protein. At least...
US20120207708 BIOMARKERS FOR CANCER-RELATED FATIGUE AND USE THEREOF  
Described herein is the identification of genes that are significantly up- or down-regulated in patients suffering from cancer-related fatigue (CRF), providing a means for the diagnosis and...
US20150247871 RISK ASSESSMENT FOR ANTIBIOTICS TREATMENT IN PATIENTS SUFFERING FROM PRIMARY NON-INFECTIOUS DISEASE BY DETERMINING THE LEVEL OF PROCALCITONIN  
A diagnostic method for the identification of a subject suffering from a primary non-infectious disease having an increased risk of an adverse outcome potentially being induced by the...
US20120322082 BIOMARKER FOR AMYOTROPHIC LATERAL SCLEROSIS AND DIAGNOSTIC KIT AND METHOD USED THEREOF  
A diagnostic marker for determining of a patient with amyotrophic lateral sclerosis (ALS), comprising an autoantibody against a human protein HMGB1 is described. A diagnostic kit for determining...
US20140322203 FORMULATIONS WITH REDUCED OXIDATION  
The invention provides formulations comprising a protein in combination with a compound that prevents oxidation of the protein. The invention also provides methods for making such formulations and...
US20140314778 FORMULATIONS WITH REDUCED OXIDATION  
The invention provides formulations comprising a protein in combination with a compound that prevents oxidation of the protein. The invention also provides methods for making such formulations and...
US20130072397 METHODS FOR THE DIAGNOSIS AND PROGNOSIS OF A TUMOR USING BCAT1 PROTEIN  
The present invention relates to methods for the diagnosis of a tumor, in particular a brain tumor, and for the estimation of a prognosis for patients afflicted with such tumor based on the...
US20130178388 Methods and Kits for the Diagnosis of Rheumatoid Arthritis  
The present invention relates to the identification and use of proteins with clinical relevance to rheumatoid arthritis (RA). In particular, the invention provides the identity of marker proteins...
US20110065609 Methods and Kits for the Diagnosis of Rheumatoid Arthritis  
The present invention relates to the identification and use of proteins with clinical relevance to rheumatoid arthritis (RA). In particular, the invention provides the identity of marker proteins...
US20130302909 ASSESSMENT OF IGF-1 LEVELS IN HIV-INFECTED SUBJECTS AND USES THEREOF  
Improved methods for determining normal IGF-1 levels in HIV infected subjects, based on a determination of the log of IGF-1 values obtained in blood-derived samples from a population of...
US20110143962 METHOD OF EVALUATING ORAL CANCER RISK IN HUMAN  
A method of providing a risk evaluation and diagnosis of human oral cancer, by examining at the presence in human saliva sample of a combination of particulate nucleic acids from bacteria, virus,...
US20110190243 DIAGNOSIS AND TREATMENT OF BACK PAIN  
The present invention relates to methods of diagnosing and/or treating lower back pain (LBP). In one embodiment, the invention relates to a system for diagnosis of a form of lower back pain in an...
US20110076778 SOLUBILIZATION OF PROTEINS IN REVERSE MICELLES BY EXTRACTION FROM A SOLID SUPPORT  
A general method for solubilizing proteins by direct extraction of an immobilized protein into a reverse micelle solution is disclosed. The reverse micelle protein solutions are amenable to...
US20140237630 SCREENING METHOD  
The present invention provides a method of screening a mammal for the onset or predisposition to the onset of a neuropsychiatric disorder. More particularly, the present invention provides a...
US20120107945 CHEMICAL REAGENT FOR MEASURING THE LEVEL OF HALOGEN AGENTS, IN PARTICULAR IN SWIMMING-POOL WATER AND ASSOCIATED MEASUREMENT METHOD  
The present invention relates to a chemical reagent for measuring the halogen-agent content, in particular in swimming pool water, and also to an associated measurement method, and such that the...
US20110189700 CYR61 AS A BIOMARKER FOR DIAGNOSIS AND PROGNOSIS OF CANCERS OF EPITHELIAL ORIGIN  
Urinary Cyr61 protein levels are up regulated in patients that have cancers of epithelial origin, i.e. breast cancer and ovarian cancer. Accordingly, the present invention is directed to methods...
US20110136146 BIOASSAY FOR POLYQ PROTEIN  
The present invention relates to bioassays for mutated polyQ protein associated with disease and their use as diagnostic tools, for monitoring disease progression or for monitoring the efficacy of...
US20130237475 SYNTHETIC GENE FOR EXPRESSING SM-14 IN PICHIA PASTORIS, METHODS FOR PRODUCING AND PURIFYING SM-14 AND THE USE THEREOF AS A VACCINE AND DIAGNOSTIC MEDIUM  
The present invention pertains to the field of production of recombinant proteins, using a synthetic gene for increased expression of the protein in Pichia pastoris. More specifically, the...