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US20110104669 |
METHOD TO PREDICT IRIS COLOR
The invention comprises a method to predict iris color of a human from a nucleic acid/protein sample comprising assaying for one or more polymorphisms in the region 5′ proximal of the OCA2 gene u...
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US20120009125 |
APOE4 AND APOJ BIOMARKER-BASED PREVENTION AND TREATMENT OF DEMENTIA
Methods, kits, screens, assays, treatments and treatment regimes for treating a patient at risk for or suffering from dementia, and particularly Alzheimer's dementia which are based upon...
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US20120088681 |
METHODS AND KITS USED IN CLASSIFYING ADRENOCORTICAL CARCINOMA
The invention encompasses methods and kits used to detect biomarkers that may be used to predict disease outcome in adrenocortical carcinoma patients.
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US20110105411 |
Disease-Associated Proteins
Disclosed are methods and compositions for early diagnosis, monitoring and treatment of an ocular disorder. In particular, the invention relates to a novel protein, that is differentially...
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US20110027184 |
PROTEIN C PATHWAY ASSOCIATED POLYMORPHISMS AS RESPONSE PREDICTORS TO ACTIVATED PROTEIN C OR PROTEIN C-LIKE COMPOUND ADMINISTRATION
The invention provides methods, nucleic acids, compositions and kits for predicting a subject's response to treatment with activated protein C or protein C like compound to identify subjects having...
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US20100298151 |
EXOSOME-ASSOCIATED MICRORNA AS A DIAGNOSTIC MARKER
The presently disclosed subject matter provides methods of diagnosis of cancer or adverse pregnancy outcomes in a subject by measuring amounts of one or more microRNAs present in cancer-derived...
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US20100330567 |
DNA MARKERS FOR MANAGEMENT OF CANCER
A method is provided for assessing allelic losses and hypermethylation of genes in CpG tumor promotor region on specific chromosomal regions in cancer patients, including melanoma, neuroblastoma...
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US20110059851 |
SHOC2 Mutations Causing Noonan-Like Syndrome With Loose Anagen Hair
The present invention is directed to methods of diagnosing Noonan-like syndrome with loose anagen hair comprising detecting a mutation in SHOC2 gene. One specific diagnostic mutation disclosed is...
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US20110223616 |
HuR-Associated Biomarkers
The present invention relates to methods of identifying gene targets, including methods of using ribonucleoprotein (RNP) immunoprecipitation-microarrays to identify cancer gene targets, such as...
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US20110251087 |
PROGNOSTIC AND DIAGNOSTIC METHOD FOR CANCER THERAPY
The present invention relates to methods for the diagnosis and prognosis of aggressive forms of cancer using a combination of gene expression signatures.
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US20120094284 |
Prediction of Early Virological Response in HCV Treatment
The present invention is based on the discovery of associations that exist between single nucleotide polymorphisms (SNPs) on chromosome 19 and virological outcomes in a diverse population of...
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US20110195512 |
NOVEL PROTEIN CAPABLE OF BINDING TO HYALURONIC ACID, AND METHOD FOR MEASUREMENT OF HYALURONIC ACID USING THE SAME
The present invention relates to a polynucleotide encoding a protein comprising an amino acid sequence shown in SEQ ID NO: 2, wherein the protein encoded by the polynucleotide has a hyaluronic acid...
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US20110105467 |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF PSYCHOTIC DISORDERS THROUGH THE IDENTIFICATION OF THE SULT4A1-1 HAPLOTYPE
Methods and compositions relate to genetic markers of psychotic disorders, e.g., schizophrenia (SZ), are provided. For example, in certain aspects methods for determinations of a SULT4A1-1...
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US20100297067 |
METHYLATION MARKERS FOR PROSTATE CANCER AND METHODS OF USE
The present invention provides methods for identifying prostate cancer by detecting nucleic acid methylation of one or more genes in one or more samples. The invention further relates to DNA...
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US20110059074 |
Knowledge-Based Proliferation Signatures and Methods of Use
The present invention provides methods and compositions for predicting patient responses to cancer treatment using a proliferation gene signature. These methods can comprise measuring in a...
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US20110045476 |
INFLAMMATORY BOWEL DISEASE PROGNOSTICS
The methods and systems of the present invention are useful in the diagnosis of inflammatory bowel disease (IBD) and in the prognosis of IBD progression and disease complications. With the present...
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US20110195074 |
Ephrin Type-A Receptor 7 Protein
The present invention provides methods and compositions for treatment, screening, diagnosis and prognosis of bladder cancer, breast cancer, colorectal cancer, gastric cancer, head and neck cancer,...
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US20120058913 |
METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-16b
The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon...
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US20100303895 |
FIXED DRUG RATIOS FOR TREATMENT OF HEMATOPOIETIC CANCERS AND PROLIFERATIVE DISORDERS
Provided herein are methods for treating cancer by administering a pharmaceutical composition comprising a fixed, non-antagonistic molar ratio of cytarabine and an anthracycline. Such methods are...
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US20100310574 |
METHODS AND COMPOSITIONS FOR THE TREATMENT AND DIAGNOSIS OF STATIN-INDUCED MYOPATHY
The invention provides compositions and kits containing an atrogin-1 inhibitor compound useful for the treatment of a statin-mediated myopathy. Kits for the diagnosis of a statin-mediated myopathy...
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US20120015830 |
MICRORNA PROFILES FOR EVALUATING MULTIPLE SCLEROSIS
The present invention provides methods, systems, and kits for evaluating multiple sclerosis (MS) in a patient. Particularly, the invention provides convenient miRNA-based tests for evaluating a...
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US20110027173 |
EPHRIN TYPE-A RECEPTOR 10 PROTEIN
The present invention provides methods and compositions for treatment, screening, diagnosis and prognosis of bladder cancer, breast cancer, colorectal cancer, head and neck cancer, kidney cancer,...
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US20120064548 |
NOVEL GENES, COMPOSITIONS, KITS, AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION AND THERAPY OF CERVICAL CANCER
The invention relates to newly discovered nucleic acid molecules and proteins associated with cervical cancer including pre-malignant conditions such as dysplasia. Compositions, kits, and methods...
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US20110003708 |
BIOMARKERS FOR THE PREDICTION OF RENAL INJURY
The present invention relates to means and methods for predicting the onset of renal injury based on measuring the expression of polynucleotides and proteins, particularly on measuring the...
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US20110091878 |
DAIRY CATTLE BREEDING FOR IMPROVED MILK PRODUCTION TRAITS IN CATTLE
Nucleic acid molecules comprising a SNP site at position 1296 of bovine uterine milk protein (UTMP) coding sequence (SEQ ID NO: 1), which SNP indicates a desirable productive life in a dairy...
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US20110236370 |
Genetic Alterations on Chromosomes 21q, 6q and 15q and Methods of Use Thereof for the Diagnosis and Treatment of Type I Diabetes
Compositions and methods for the detection and treatment of T1D are provided.
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US20110046005 |
METHOD AND NUCLEIC ACIDS FOR THE ANALYSIS OF COLON CELL PROLIFERATIVE DISORDERS
Provided are methods and nucleic acids for detecting, differentiating or distinguishing between colon cell proliferative disorders by analysis of one or more of the genes Versican, TPEF,...
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US20110313276 |
NON-INVASIVE IN VITRO METHOD FOR QUANTIFYING LIVER LESIONS
An in-vitro non-invasive method for quantifying the lesions of the liver of the patient with metabolic steatosis addressing a diagnostic target, i.e. fibrosis, steatosis and/or steato-hepatitis...
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US20110165148 |
NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 162P1E6 USEFUL IN TREATMENT AND DETECTION OF CANCER
A novel gene (designated 162P1E6) and its encoded protein, and variants thereof, are described wherein 162P1E6 exhibits tissue specific expression in normal adult tissue, and is aberrantly...
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US20120070902 |
METHOD FOR ANALYSIS OF SUGAR CHAINS BY MASS SPECTROMETRY
Provided is a highly accurate means for analyzing a sugar chain contained in a biological sample by MALDI-TOF MS or such a mass spectrometry method. In the present invention, it was found to be...
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US20110256580 |
LC-MFR-MS-Based Method and Apparatus for Screening a New Drug Candidate
The present invention relates to a method for screening a new drug candidate using a liquid chromatography/microfluidic device/mass spectrometry system, and to a liquid chromatography/microfluidic...
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US20110183019 |
METHODS OF SCREENING FOR AND TREATING AUTISM SPECTRUM DISORDERS AND COMPOSITIONS FOR SAME
Disclosed are methods of screening for an autism spectrum disorder, compositions that inhibit the release of molecules that disrupt the blood-brain barrier, compositions for treating autism...
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US20110104697 |
METHODS AND COMPOSITIONS FOR DIAGNOSING AND MONITORING TRANSPLANT REJECTION
Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described....
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US20110269141 |
TARGET PROTEIN AND TARGET GENE FOR DRUG DISCOVERY, AND SCREENING METHOD
The problems of the present invention are to provide target proteins and target genes for bioactive substances such as drugs, and means that enable the development of novel bioactive substances...
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US20110009469 |
COMPOSITIONS AND METHODS OF TREATING NEOPLASIA
The present invention provides compositions and methods featuring microRNA polynucleotides for the diagnosis, treatment or prevention of neoplasia.
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US20110027797 |
Method for the Diagnosis of Higher- and Lower-Grade Astrocytoma Using Biomarkers and Diagnostic Kit Thereof
Disclosed is a method of diagnosing the presence of higher grade astrocytoma/glioblastoma (GBM) or lower-grade grade astrocytoma (DA or AA) in a human subject using secreted or plasma membrane...
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US20120004119 |
GENE EXPRESSION MARKERS OF ONCOLYTIC VIRUS SENSITIVITY
A method of predicting an efficacy of an oncolytic virus treatment for a tumor comprises calculating a single-gene predictor score for each of a plurality of genes; calculating a predictor score...
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US20110143948 |
MOLECULAR SIGNATURES AND BIOMARKERS ASSOCIATED WITH MELANOMA AND METHODS OF USE THEREOF
Described herein are methods for evaluating the risk of melanoma in subjects. The methods involve detecting and quantifying one or more biomarkers associated with melanoma in a biological sample...
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US20110033849 |
OVINE IDENTIFICATION METHOD
The invention relates to method for identifying an ovine with a genotype indicative of one or more altered performance traits, the method including the step of detecting, in a sample derived from...
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US20110039344 |
METHOD AND TESTING A SUBJECT THOUGHT TO BE PREDISPOSED TO LUNG CANCER
The present invention concerns a method of testing a human thought to be predisposed to having lung cancer which comprises the step of analyzing a biological sample from said human for detecting...
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US20110111393 |
PNA Probes, Mixtures, Methods And Kits Pertaining To The Determination Of Mycoplasma and related Mollicutes
This invention is related to PNA probes, probe sets, mixtures, methods and kits pertaining to the determination of Mycoplasma and related Mollicutes.
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US20120122087 |
5-Hydroxymethylcytosine as a biomarker for early detection, treatment and prognostic monitoring of cancer
The present invention is related to the use of 5-hydroxymethylcytosine or a biomolecule having general structure of 5-hydroxymethycytosine as a biomarker for the detection, treatment monitoring,...
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US20110097710 |
Methods for detecting atrial fibrillation and related conditions
Methods for detecting disorders associated with atrial fibrillation, and, thus, at risk for stroke and/or heart failure) in a subject based on a monitoring plasma levels of apelin are provided....
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US20110027813 |
Compositions for Binding to Assay Substrata and Methods of Using
Compositions and methods for binding to assay substrata in a stable and protective manner, thereby enhancing assay performance, are provided. The compositions comprise lyotropic materials (for...
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US20110053281 |
Genetic variants on CHR 11Q and 6Q as markers for prostate and colorectal cancer predisposition
It has been discovered that certain polymorphic markers on chromosome 6 and chromosome 11 are indicative of a susceptibility to prostate cancer and colon cancer. The invention describes diagnostic...
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US20110082187 |
MARKERS AND METHODS RELATING TO THE ASSESSMENT OF ALZHEIMER'S DISEASE
Use of clusterin as a biomarker of Alzheimer's disease (AD), particularly methods and compositions for detection of clusterin in a biological sample and assessment of in vivo pathology, disease...
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US20110047643 |
DRY BEAN LINE 08550815
The invention provides seed and plants of the bean line designated 08550815. The invention thus relates to the plants, seeds and tissue cultures of bean line 08550815, and to methods for producing...
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US20110135575 |
METALLOPROTEIN MRI CONTRAST AGENTS AND RELATED METHODS
The present invention generally relates to Magnetic Resonance Imaging (MRI) analysis of the location, presence, and/or quantity of a particular molecule or material. In some embodiments, the...
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US20110059089 |
Protein Markers for Cardiovascular Events
The present invention relates to a method for predicting the risk of a subject developing a cardiovascular event comprising detecting at least one biomarker in (a sample of) the cardiovascular...
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US20110159602 |
ANALYSIS OF VI SACCHARIDES
Salmonella typhi Vi saccharide can be assayed in two new ways. First, its proton NMR spectrum can be used, with comparison to an internal Standard permitting quantitative analysis. Second, anion...
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