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US20090011518 Device and Method for Detection of Fluorescence Labelled Biological Components  
A sample acquiring device for detection of biological components in a liquid sample is provided comprising a measurement cavity for receiving a liquid sample, wherein the measurement cavity has a...
US20080167198 Filter based detection system  
The present invention provides an apparatus and a method for detecting an analyte in a liquid sample with reduced complexity and response time without sacrificing multiplexing capabilities or...
US20110065807 PH SENSITIVE BIODEGRADABLE POLYMERIC PARTICLES FOR DRUG DELIVERY  
The present invention generally relates to polymers and particles, such as nanoparticles. The particles and polymers generally include one or more buffering components. Additionally, the particles...
US20070238185 Oxide Layers on Silicon Substrates for Effective Confocal Laser Microscopy  
Methods of performing confocal laser microscopy on a polymer array disposed on a silicon wafer substrate, the method comprising the steps of providing a silicon wafer substrate having a top side...
US20110020946 CONVERSION OF JUST-CONTINUOUS METALLIC FILMS TO LARGE PARTICULATE SUBSTRATES FOR METAL-ENHANCED FLUORESCENCE  
The present invention relates to a method of producing silver films having large nanoparticles caused by cracking during anaerobic annealing to provide surfaces that exhibit increased metal...
US20080095669 Apparatus for and method of measuring bio-chips using uniform total internal reflection illumination  
Disclosed herein is an apparatus for and method of measuring bio-chips, which can implement an illumination method of a novel type that illuminates a bio sample (which may be also referred to as a...
US20150004715 Encapsulated Fluorescent Metal Nanoparticles as Indicators for Radiation  
Encapsulated fluorescent metal nanoparticles for radiation detection comprising metal ions in an aqueous solution encapsulated in a nanocapsule, wherein the metal ions form atoms when exposed to...
US20130323857 NEW IRIDIUM-BASED COMPLEXES FOR ECL  
Novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, for example in electrochemiluminescence based detection of an analyte.
US20070287186 Use of Two-Photon Excited Fluorescence in Assays of Clinical Chemistry Analytes  
The invention relates to an in vitro diagnostic method for quantification of a clinical chemistry analyte from a clinical sample wherein the clinical chemistry analyte undergoes a chemical...
US20050009199 Method of measuring number of molecules or molecular density of a sample fixed on a substrate surface  
The method of measuring the number of molecules or the molecular density of a sample according to the present invention includes the steps of: a) labeling each of the molecules with a preset...
US20140099630 QUANTITATIVE DETERMINATION METHOD FOR TARGET PARTICLES, PHOTOMETRIC ANALYSIS DEVICE, AND COMPUTER PROGRAM FOR PHOTOMETRIC ANALYSIS  
The method of the present invention includes: preparing a sample solution containing the target particles and luminescent probes to be bound to the target particles, and binding these in the...
US20120329171 DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT  
The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid.
US20110177609 DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT  
The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid.
US20150192506 APPARATUS, SYSTEM, AND METHOD FOR COLLECTING A TARGET MATERIAL  
This disclosure is directed to an apparatus, system and method for retrieving target material from a suspension. A system includes a processing vessel, such as an Eppendorf tube, a syringe or a...
US20100003765 METHODS AND SYSTEMS FOR MITIGATING OXYGEN ENHANCED DAMAGE IN REAL-TIME ANALYTICAL OPERATIONS  
Methods and systems for performing analytical reactions under reduced or non-oxygen conditions, where such reactions are potentially subject to damaging effects of oxygen, including particularly...
US20150177145 DEVICE AND ASSOCIATED METHODS FOR PERFORMING LUMINESCENCE AND FLUORESCENCE MEASUREMENTS OF A SAMPLE  
Apparatuses and methods of optically analyzing fluid within a pipette are described herein. In an embodiment, an optical reader subassembly includes a pipette having a tip, the pipette configured...
US20090130772 Apparatus and method for collecting data on light-emitting reactions  
The invention concerns an apparatus and a method for collecting data on a set of light-emitting molecular reactions. The apparatus comprises a holder for a reaction vessel comprising a plurality...
US20100255488 FRET-LABELED COMPOUNDS AND USES THEREFOR  
FRET-labeled compounds are provided for use in analytical reactions. In certain embodiments, FRET-labeled nucleotide analogs are used in place of naturally occurring nucleoside triphosphates or...
US20140127717 HYDROXAMATE SUBSTITUTED AZAINDOLINE-CYANINE DYES AND BIOCONJUGATES OF THE SAME  
Hydroxamate substituted azaindoline cyanine dyes, conjugates thereof and methods of using the same are provided. The subject cyanine dyes include an azaindoline ring having a hydroxamate...
US20110195516 WIRE GRID SUBSTRATE STRUCTURE AND METHOD FOR MANUFACTURING SUCH A SUBSTRATE  
The present invention relates to a multi-layered substrate structure comprising at least one carrier layer (11), a first layer (12), said carrier layer and first layer being in contact with each...
US20100291703 BIOSENSOR  
A biosensor applicable to an environment suitable for biosensing is provided, which is a solid-state element for performing detections in an aqueous environment. The biosensor at least includes a...
US20120214194 PROCESS FOR SYNTHESIZING EPICCONONE ANALOGS  
The present invention relates to a process for the total synthesis of epicocconone analogs of formula (I): The invention also relates to novel epicocconone analogs.
US20090137059 Inorganic Polymers and Use of Inorganic Polymers for Detecting Nitroaromatic Compounds  
A method for detecting an analyze that may be present in ambient air, bound to a surface or as part of complex aqueous media that includes providing a metallole-containing polymer or copolymer,...
US20080176263 Materials and Methods for Efficient and Accurate Detection of Analytes  
The present invention provides diagnostic methods and devices that can be used to assay a medium, such as tissue in vivo or a sample in vitro (e.g. biological sample or environmental sample), in...
US20080160548 Microoptical Detection System and Method for Determination of Temperature-Dependent Parameters of Analytes  
The invention relates to a microoptical detection system and a method for detecting analytes by means of time-resolved luminescence. This serves for determination of temperature-dependent...
US20110175982 METHOD OF FLUORESCENT NANOSCOPY  
An analysis of an object dyed with fluorescent coloring agents carried out with the aid of a fluorescent microscope which is modified for improved resolving power and called a nanoscope. The...
US20130102087 DEVICE, SYSTEM AND METHOD FOR RAPID DETERMINATION OF A MEDICAL CONDITION  
Provided is a system and method for determination of a medical condition, the system including a disposable cartridge adapted to receive a volume of a body fluid, the cartridge comprising a...
US20110059462 AUTOMATED PARTICULATE CONCENTRATION SYSTEM  
An automated system for concentrating potentially harmful substances from various water types or other non-viscous liquids to facilitate detection of those substances is disclosed herein. The...
US20070254372 Method and device for the detection of molecular interactions  
The invention relates to devices and methods for the detection of specific interactions between probe and target molecules. In particular, the invention relates to methods for the qualitative...
US20050233469 Activity-based probes for protein tyrosine phosphatases  
Provided are compounds capable of covalently binding to a protein tyrosine phosphatase (PTP). The compounds comprise Formula A: Also provided are compositions comprising one of the above compounds...
US20070269901 BIOLOGICAL AND CHEMICAL MICROCAVITY RESONANT SENSORS AND METHODS OF DETECTING MOLECULES  
Resonant sensors and methods of detecting specific molecules with enhanced sensitivity. Optical energy is introduced into a microcavity, such as a silica toroid-shaped microcavity. The microcavity...
US20130316334 TRANSFORMATION OF MATERIAL INTO AN OPTICALLY MODULATING STATE VIA LASER RADIATION  
A method for the transformation of material (e.g. plastic material) into an optically modulating state via laser radiation is described. The optically modulating state may be a state in which...
US20090317917 Biosensor and Method for Detecting Analytes  
The present invention concerns in general a biosensor in the form of a microchip for the optical detection of analytes and a method using this biosensor. In particular the invention concerns...
US20140256057 CHEMICAL SENSOR, BIOMOLECULE DETECTION APPARATUS, AND BIOMOLECULE DETECTION METHOD  
[Object] To provide a chemical sensor, a biomolecule detection apparatus, and a biomolecule detection method capable of detecting a biomolecule with high accuracy. [Solving Means] A chemical...
US20120309103 METHOD FOR MEASURING LUMINESCENCE AT A LUMINESCENCE DETECTION WORKSTATION  
A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a...
US20110151576 METHOD TO ASSESS MULTIPHASE FLUID COMPOSITIONS  
A method for the assessment of a multiphase (aqueous and organic) sample phase, the method comprising adding at least one detection molecule to the multiphase sample; detecting a signal emitted...
US20100178664 OPTICAL MEASUREMENT METHOD FOR DETERMINING THE PH OF A MEDIUM USING AGELADINE A AS A FLUORESCENT PH INDICATOR  
An optical measurement method for determining a pH of a medium includes adding a fluorescent pH indicator to the medium. The pH indicator is based on naturally-obtained or synthesized ageladine A....
US20090215189 Sensor of species including toxins and chemical warfare agents  
The present invention generally relates to emissive materials, devices, and related methods. In some cases, the present invention provides sensors and methods for the determination of analytes,...
US20090068757 APPARATUS, PROCESS AND KIT FOR DETECTING ANALYTES IN A SAMPLE  
The invention relates to an apparatus (100) for detecting analytes (26) in a sample comprising—a base carrier (10); —a multitude of sensor carriers (18) which are arranged on the base carrier (10)...
US20110306146 Parallel Screening Supercritical Fluid Chromatography  
The invention provides an apparatus for supercritical fluid chromatography. The apparatus comprises a binary pump; an autosampler; a sampling valve; a first and second port switching valve; a...
US20110059441 METHOF OF PRODUCING BIOACTIVE PAPER  
The present disclosure relates to methods for attaching bioactive agents to paper products by contacting the paper with a solution comprising colloidal support particles where said colloidal...
US20110223105 NEW 5-AMINOLEVULINIC ACID PRODRUGS FOR USE IN PHOTODYNAMIC THERAPY AND PHOTODYNAMIC DIAGNOSIS  
There is provided a compound of Formula and salts thereof wherein R1 is an imine or an alkylated imine, said imine or alkylated imine comprising a linear or branched alkyl group of length C1 to...
US20100291547 FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS  
The present disclosure is directed to fluorogenic schiff base-forming dyes capable of detecting analytes containing aldehyde and ketone groups. The dyes contain nucleophilic hydrazinyl appendages...
US20100248386 SEMICONDUCTOR PHOSPHOR NANOPARTICLE ASSEMBLY, PRODUCING METHOD THEREOF AND SINGLE MOLECULE OBSERVATION METHOD BY USE THEREOF  
The present invention provide a semiconductor phosphor nanoparticle assembly which exhibits no variation in emission wavelength and emission intensity for every particle and is capable of...
US20080261239 DETECTING MOLECULAR INTERACTIONS  
The present disclosure features a variety of compositions, kits, and methods that are useful for, inter alia, detecting and/or analyzing an interaction between two molecules, a target molecule and...
US20140106462 MICROFLUIDIC SYSTEM FOR HIGH-THROUGHPUT, DROPLET-BASED SINGLE MOLECULE ANALYSIS WITH LOW REAGENT CONSUMPTION  
A microfluidic device for a confocal fluorescence detection system has an input channel defined by a body of the microfluidic device, a sample concentration section defined by the body of the...
US20140086844 LUMINESCENT COMPOUNDS  
Dyes and photoluminescent compounds based on polymethine dyes that contain at least one alkyl-phosphonate or substituted alkyl-phosphonate group, including the synthetic precursors, methods of...
US20110045993 MICROFLUIDIC DEVICE FOR ASSESSING OBJECT/TEST MATERIAL INTERACTIONS  
An object/test material interaction microti iridic device comprising a sample inlet adapted to receive a fluid sample comprising a plurality of objects, an outlet adapted to output the fluid...
US20150243695 IMAGING SYSTEMS WITH ACTIVATION MECHANISMS  
An imaging system may be used to image a fluid sample containing particles. The imaging system may include a fluid channel that receives the fluid sample and a reactive agent that selectively...
US20150079694 MEASURING CASSETTE AND MEASURING DEVICE FOR THE DETECTION OF TARGET MOLECULES IN A LIQUID SAMPLE BY MEASUREMENT OF FLUORESCENCE EMISSION AFTER EXCITATION IN AN EVANESCENT FIELD  
An interchangeable disposable measuring cassette for insertion into a measuring apparatus for detecting target molecules in a liquid sample by measuring fluorescence emission has a flow...