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US20070161116 Differential analysis of cell surface proteins on closed membrane structures by labelling with dyes in the presence of an internal standard  
Disclosed are matched fluorescent reagents and a method for reproducibly labelling membrane components, such as those expressed on the cell surface, and subsequent differential analysis of the...
US20100197039 FLUORESCENT MATERIALS FOR HIGHLY SENSITIVE AND SELECTIVE SENSING OF AMINES AND NANOFIBRIL MATERIALS MADE THEREFROM  
A fluorescence sensory material with high sensitivity, selectivity, and photostability has been developed for vapor probing of organic amines. The sensory material is a...
US20080293154 Apparatus and method for detecting target  
The target detecting apparatus includes: a first container having a metal inside and containing a fluorescent particle which generates fluorescence on exposure to light and quenches the...
US20120178177 Biological Components Within the Cerebrospinal Fluid  
The invention provides novel methods for isolating, characterizing, comparing, and using biological components that are present in the cerebrospinal fluid. Such biological structures, called...
US20110046000 METHODS TO INCREASE THE PHOTOSTABILITY OF DYES  
The presently disclosed subject matter provides dyes having an improved photostability, biosensors comprising such dyes, and methods of use thereof, including methods for detecting target...
US20080118944 SEQUENTIAL ANALYSIS OF BIOLOGICAL SAMPLES  
Methods for probing multiple targets in a biological sample are provided. The methods include the steps of providing a biological sample containing multiple targets adhered to a solid support,...
US20050233468 Method of local rheological measurement by fluorescent microscopy and a new fluorescent probe for polyacrylamide polymer molecules  
The present invention is directed to a complex comprising of a polymer and a fluorescent probe, a method for its preparation and use thereof for measuring dynamics of single molecules in a...
US20110262906 MICROFLUIDIC MULTIPLEXED CELLULAR AND MOLECULAR ANALYSIS DEVICE AND METHOD  
A sequential flow analysis tool comprising a microti iridic device having a fluid path defined within a substrate between an input and an output is described. The device includes a capture chamber...
US20100075336 SYSTEM FOR PERFORMING MULTI-FORMATTED ASSAYS  
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations in which discrete aspects of the assay are performed on fluid samples contained in sample...
US20050037500 Method and apparatus for detecting a leak of external air into a plasma reactor  
A method (300) and a corresponding apparatus for detecting a leak of external air into a plasma reactor are proposed. The method includes: establishing (340) a plasma inside the reactor, the...
US20080044919 Analyte Detection Using Time-Resolved Photon Counting Fluorescence  
Samples are exposed to a fluorescent probe that binds to a known target analyte. Unbound probe is removed and the sample is exposed to a pulsed laser light of preferred wavelength, where the laser...
US20140342384 FLUORESCENT PROBE  
A compound represented by the formula (I) (R1 represents a substituent on the benzene ring; R2 represents a monovalent substituent; R3 and R4 represent hydrogen atom, or an alkyl group; R5 and R6...
US20140080225 METHODS AND DEVICES FOR XEROGEL BASED SENSORS  
Fluorescence based sensing systems and methods that exploit xerogels are provided. Embodiments of the invention encompass a sensing system that includes: an optical excitation source emitting over...
US20100167412 SENSOR SYSTEM FOR DETERMINING CONCENTRATION OF CHEMICAL AND BIOLOGICAL ANALYTES  
A sensor system for determining a concentration of chemical and biological analytes is disclosed, which comprises a disposable reagent-carrying pipette tip; a liquid handling unit to which the...
US20100216652 Low Level Fluorescence Detection at the Light Microscopic Level  
The present invention discloses methods of removing unwanted fluorescence from a sample by photobleaching said sample to enhance detection of proteins and fragments thereof, polynucleotides and...
US20130309725 Methods and Devices for In Situ Nucleic Acid Synthesis  
Disclosed are compositions, methods and devices for the in situ synthesis of nucleic acids. In an exemplary embodiment, a support-bound oligonucleotide is elongated by addition of one or more...
US20130034913 Method for Investigating a Specimen Containing Fluorescing Dyes with the Aid of a Microscope  
In order to investigate a specimen (30) with the aid of a microscope (20), dye particles (40, 42) in the specimen (30) are excited to fluoresce with the aid of a first illumination light beam...
US20130039858 NIR MATERIALS AND NANOMATERIALS FOR THERANOSTIC APPLICATIONS  
Novel fluorescent dye comprising metal oxide nanoparticles are prepared where the nanoparticles are as small as 3 nm or up to 7000 nm in diameter and where the dye is bound within the metal oxide...
US20120115241 SYSTEMS, DEVICES, AND METHODS FOR REMOTELY INTERROGATED CHEMOSENSOR ELECTRONICS  
Systems, devices and methods for remotely interrogating sensor electronics are described. In one embodiment, a system for detecting and localizing chemical analytes is described. This system...
US20090117664 LIQUID SENDING METHOD OF LIQUID IN SUBSTRATE CHANNEL AND LIQUID SENDING APPARATUS  
A liquid sending method includes the step of introducing either one fluid of a gas or an insulating liquid into a channel disposed on a substrate, thereby dividing a liquid flowing in the channel...
US20090181396 METHODS AND SYSTEMS FOR ANALYSIS OF FLUORESCENT REACTIONS WITH MODULATED EXCITATION  
Methods, systems and their components for monitoring fluorescent signals and particularly transient fluorescent signals from reaction mixtures of interest, which methods and systems employ...
US20080064752 Acid Addition Salts Of-5-Aminolevulinic Acid Or Its Derivatives  
The present invention provides an acid addition salt of 5-aminolevulinic acid (5-ALA) or of a 5-ALA derivative (e.g. a 5-ALA ester) with an acid which has a pKa of about 5 or less, preferably...
US20090220948 Methods and Device for Transmitting, Enclosing and Analysing Fluid Samples  
A microfluidic device for analysing a fluid sample comprises at least one sample transmission channel; at least one multi-functional channel; and at least one reactor module which provides a fluid...
US20080145856 Method and Apparatus for Detecting A Ligand in A Fluid  
In a method for detecting at least one ligand that is suspected to be contained in the fluid that is being tested, at least one marker that is suitable for binding to the ligand is placed in the...
US20130034912 CENTRIFUGAL FORCE-BASED MICROFLUIDIC DEVICE AVAILABLE FOR RELIABILITY VERIFICATION, AND ANALYZING METHOD USING THE SAME  
A centrifugal force-based microfluidic device for a multiplexed analysis and an analyzing method using the same are provided. The microfluidic device includes a platform and a microfluidic...
US20060194307 Cell measuring and sorting chip  
The present invention provides a cell sorting device using an inexpensive chip capable of being exchanged for each sample for cell sorting. The cell sorting device uses flow paths formed on the...
US20070081163 Method and apparatus for scanned beam microarray assay  
A system and method provides for chemical and/or biochemical analysis using a microarray interrogated by a resonantly scanned beam of light.
US20120058464 Assay Methods Using Array of Test Zones  
A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test...
US20110053278 SYSTEMS AND METHODS FOR ENHANCING FLUORESCENT DETECTION OF TARGET MOLECULES IN A TEST SAMPLE  
Systems and methods for enhancing fluorescent detection of target molecules in a test sample are for use with an irradiating device. First fluorophores are provided for absorption of EMF...
US20100081214 CHROMATOGRAPHIC ASSAY SYSTEM  
The present application discloses an analyte detection apparatus having at least one reservoir area and a wicking membrane, wherein a labeled specific binding partner is impregnated on the...
US20080312092 Photoinduced Signal Amplification Through Externally Sensitized Photofragmentation in Masked Photosensitizers  
A method of photochemically amplifying the chemical signal associated with unmasking a photosensitizer and releasing a radical leaving group when a photochemical chain reaction is initiated by a...
US20100173429 METHODS USING NOVEL CHEMILUMINESCENT LABELS  
Methods using chemiluminescent label compounds and chemiluminescent labeled conjugates are provided. The compounds comprise an acridan ring bearing an exocyclic ketene dithioacetal group and...
US20070243618 Device and method for non-invasive oxygen sensing of sealed packages  
The present invention provides a system, method and composition for detecting exposure of the contents of a container to one or more gases using a gas sensitive package sensor. The gas sensitive...
US20110244579 Valve Analytical System  
A lab on a valve analytical system includes a rotary sample preparation assembly having a stator and a rotor. The rotor includes a plurality of integral syringe pumps which can be aligned with...
US20090233377 MICROPARTICLE-PROTEIN COMPLEX, METHOD FOR PRODUCTION OF THE COMPLEX, SEMICONDUCTOR DEVICE, AND FLUORESCENT LABELING METHOD  
First, an ammonium acetate solution and an acetate solution of a metal such as Cd or Zn are mixed, so as to form an ammonium complex of the metal. Next, an apoferritin solution and thioacetic acid...
US20120142045 USE OF AN AMORPHOUS SILICON LAYER AND ANALYSIS METHODS  
A method of detecting substances or reactions of substances in a sample, comprising: (i) providing a layer (CS) based on hydrogenated or unhydrogenated amorphous silicon with attached probes, (ii)...
US20050037402 Device and process for direct quantitative in vitro determination of a substance that is contained in a sample  
This invention relates to a device and a process for direct quantitative in vitro determination of a substance that is contained in a sample. The device according to the invention comprises...
US20080044924 WATER QUALITY EVALUATION METHOD AND SUBSTRATE CONTACTING APPARATUS USED  
A water quality evaluation method capable of evaluating quality of water to be evaluated with high precision and a substrate contacting apparatus used in the water quality evaluation method are...
US20140206096 STABLE INDIUM-CONTAINING SEMICONDUCTOR NANOCRYSTALS  
Nanocrystals having an indium-based core and methods for making them and using them to construct core-shell nanocrystals are described. These core-shell nanocrystals are highly stable and provide...
US20110223110 STABLE INDIUM-CONTAINING SEMICONDUCTOR NANOCRYSTALS  
Nanocrystals having an indium-based core and methods for making them and using them to construct core-shell nanocrystals are described. These core-shell nanocrystals are highly stable and provide...
US20130224871 Novel Amine-Substituted Tricyclic Fluorescent Dyes  
The present invention relates to polycyclic compounds of the general formula (I) which are distinguished by an amine substituent NR6R7 on the central carbon atom of the chromophore, to processes...
US20110070659 SAMPLE PRESENTATION DEVICE  
The present invention relates to sample presentation devices useful in performing analytical measurements. These devices have been configured to enable various aspects of liquid handling such as:...
US20090130700 Device and Method for Determining the Concentration of a Substance  
The invention provides a method for determining a concentration of a substance in a compartment comprising exciting an endogenous compound, or a functional part, derivative, analogue or precursor...
US20090253118 LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES  
Provided herein are compounds or fluorogenic probes which can be used as reagents for measuring, detecting and/or screening ROS or RNS such as peroxynitrite or hypochlorite. Provided also herein...
US20120156794 METHOD FOR THE EXTRACTION AND DETECTION OF FAT-SOLUBLE COMPONENTS FROM BIOLOGICAL MATERIALS  
The invention relates to a method for analysis of fat-soluble components, in particular fat-soluble dyes, from biological materials, in particular foods and feeds, having facilitated extraction of...
US20140065720 OPTICAL EMISSION COLLECTION AND DETECTION DEVICE AND METHOD  
This invention generally relates to optical devices that can collect and detect signal emissions effectively while allowing the excitation light path and the sample flow path to coexist...
US20090017554 DETECTION AND MIXING IN A CONDUIT IN INTEGRATED BIOANALYSIS SYSTEMS  
Apparatuses and methods in which detection is integrated with various liquid processing and environmental control functions to create integrated bioanalysis systems are disclosed. Though the...
US20130004986 Use of luminescent Ir(III) and Ru(II) complexes  
The present invention relates to the use of luminescent Ir(III) and Ru(II) complexes and their application in electro-chemiluminescence and bio-labelling. The use refers to the labelling and...
US20100105149 FLUORESCENT DYE-LABELED GLUCOSE BIOPROBE, SYNTHESIS METHOD AND USAGE THEREOF  
The present invention relates to a fluorescent dye-labeled glucose analog, and a synthesis method and usage of the same, and more particularly, to novel glucose α and β anomers in which a...
US20110159605 Surface Grafted Conjugated Polymers  
A surface grafted conjugated polyelectrolyte (CPE) is formed by coupling a CPE by a coupling moiety to the surface of a substrate. The substrate can be of any shape and size, and for many uses of...