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US20080213917 LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES  
The present invention provides a novel class of macrocyclic compounds as well as complexes formed between a metal (e.g., lanthanide) ion and the compounds of the invention. Preferred complexes...
US20100311184 AZO HETEROCYCLIC DYES AND THEIR BIOLOGICAL CONJUGATES  
Azo heterocyclic compounds that are substantially non-fluorescent or only weakly fluorescent useful as energy acceptors. The chemically reactive compounds possess utility for labeling a wide...
US20080038835 Reference Member for Fluorescence Measurements, and Method for the Production Thereof  
Disclosed is a reference member for fluorescence measurements, comprising a fluorescent layer (2) by means of which fluorescent radiation is emitted during optical irradiation and at least two...
US20110294225 Method for Detecting Optical Signals, Microfluidic Mixing Chip Having Light Emitting Compound and System Thereof  
A method for detecting optical signals, a microfluidic mixing chip having light emitting compound and a system thereof are provided. The microfluidic mixing system comprises the microfluidic...
US20070269382 Nanoparticles and Their Use for Multifunctional Bioimaging  
The present invention relates to fluorescent, radio-opaque and magnetic quantum nanoparticles, useful as multifunctional contrast agents or probes for in vivo bioimaging, and methods of their use....
US20120077279 Silica Nanoparticles Incorporating Chemiluminescent And Absorbing Active Molecules  
Nanoparticles incorporating absorbing materials, e.g., an absorber dye, which under appropriate conditions exhibit chemiluminescence. The nanoparticles can be mesoporous silica nanoparticles or...
US20080020483 Fluorescence Detecting Method  
The invention provides a fluorescence detecting method, comprising irradiating an excitation light in the UV range on a sample containing a nanoparticle fluorescent material having an emission...
US20130210158 QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS  
Quaternary nitrogen heterocyclic boronic acid-containing compounds are described, which are sensitive to glucose and fructose, as well as a variety of other physiologically important analytes,...
US20140045203 TEST ELEMENT FOR DETECTING AN ANALYTE IN A SAMPLE  
The invention relates to a test element for detecting at least one analyte in a sample, in particular for detecting at least one metabolite in a bodily fluid. The test element comprises at least...
US20070269821 LATERAL FLOW DEVICES  
An analytical test for an analyte comprises (a) a base, having a reaction area and a visualization area, (b) a capture species, on the base in the visualization area, comprising nucleic acid, and...
US20100184059 COMPOSITIONS  
A composition for carrying out a chemical or biochemical reaction, said composition being in a freeze-dried form and comprising (i) a set of reagents comprising at least some of the chemical or...
US20080220441 Advanced drug development and manufacturing  
X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the...
US20070212793 Fluorescent ion doped glass and method for using the fluorescent ion doped glass to enhance fluorescence imaging techniques  
A fluorescent ion doped glass (or other fluorescing material) and a method for using the fluorescent ion doped glass to enhance a fluorescence imaging technique are described herein. In one...
US20110014721 HYDROPHILIC CHEMILUMINESCENT ACRIDINIUM LABELING REAGENTS  
In accordance with the present invention, it has been discovered that introduction of hydrophilic sulfoalkyl substituents and/or hydrophilic linkers derived from homocysteic acid, cysteic acid,...
US20070026532 Method and system for detecting fluorescence from microarray disk  
In a fluorescence detection method: each of one or more biological specimens is irradiated with excitation light while a substrate disk is rotated, where the one or more biological specimens are...
US20100267010 Method and Apparatus for Real-Time Analysis of Chemical, Biological and Explosive Substances in the Air  
A device for real-time analysis of airborne chemical, biological and explosive substances has at least a gas analysis sensor, fluorescence/luminescence sensor and a sensor for determining the...
US20140038306 Methods, Systems, and Devices Relating to Open Microfluidic Channels  
The various embodiments described herein relate to fabricating and using open microfluidic networks according to methods, systems, and devices that can be used in applications ranging from...
US20140106984 FLOW PASSAGE DEVICE AND TESTING SYSTEM USING THE SAME  
A real time analysis in accordance with temperature change and highly sensitive detection are permitted. A flow passage device has a flow passage (1) and is able to heat a fluid in the flow...
US20100022021 NEW AZIDE SUBSTITUTED NAPHTHYLENE OR RYLENE IMIDE DERIVATIVES AND THEIR USE AS REAGENTS IN CLICK-REACTIONS  
Novel mono-azide substituted rylene-imide derivatives, their use in methods for the detection of analytes and reagents kits for the detection of analytes comprising said novel mono-azide...
US20080213915 SYSTEM AND METHOD FOR THE MEASUREMENT OF MULTIPLE FLUORESCENCE EMISSIONS IN A FLOW CYTOMETRY SYSTEM  
A system and method for the measurement of multiple fluorescence emissions in a flow cytometry system is disclosed where each excitation light source is modulated with a different frequency. A...
US20090176313 Fluorescent Compound and Labeling Agent Comprising the Same  
A novel fluorescent compound having a high light fastness, high fluorescence quantum yield and sharp absorption spectrum, which emits fluorescence having a wavelength in long wavelength region, as...
US20130071849 FRET-LABELED COMPOUNDS AND USES THEREFOR  
FRET-labeled compounds are provided for use in analytical reactions. In certain embodiments, FRET-labeled nucleotide analogs are used in place of naturally occurring nucleoside triphosphates or...
US20090087919 Method and Apparatus for Measuring Protein Post-Translational Modification  
The present invention includes a method for analyzing reactions. The method includes the steps of providing a solution of at least one acceptor chemical and at least one donor chemical. The donor...
US20090311799 Nucleic Acid Materials for Nonradiative Energy Transfer and Methods of Production and Use  
Nucleic acid materials for FRET-based luminescence and methods of making and using the nucleic acid materials are provided. The nucleic acid materials provide an innovative and synergistic...
US20100075859 SYSTEM AND METHOD FOR SOLUTION BASED MULTIPARAMETER ANALYSIS OF ANALYTES  
There is described a system for multiparameter analysis of analytes. The system comprises: 1) primary supports (1) with a largest dimension (3) of 500 μm or less suspended in use in a fluid...
US20080199875 UNSYMMETRICAL CYANINE DIMER COMPOUNDS AND THEIR APPLICATION  
Embodiments of the present invention provide methods and nucleic acid reporter molecules for the detection of nucleic acid in a sample. The nucleic acid reporter molecule comprises two...
US20120058050 LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES  
The present invention relates to a loaded particle comprising at least one fluorescent dye, and in particular, a fluorescent dye with a large Stokes shift. The invention further relates to a...
US20080044922 System and Method of Compensating for System Delay in Analyte Analyzation  
A system configured to determine information related to one or more gaseous analytes in a body of gas comprises a luminescable material, one or more emitters, one or more photosensitive detectors,...
US20100279420 BIOSENSORS, AND METHOD AND KITS FOR USING SAME  
A stabilised thylakoid membrane formulation comprising thylakoid membranes in a buffered solution and liposomes, wherein the formulation has a ratio of chlorophyll/liposomes of at least about...
US20080070234 Measuring Range Extension of Chromatographic Rapid Tests  
A method for the quantitative determination of an analyte in a sample is provided comprising: (a) providing an analyte-specific substance which is able to undergo a reaction which generates a...
US20140045209 Structures for Enhancement of Local Electric Field, Light Absorption, Light Radiation, Material Detection and Methods for Making and Using of the Same  
Microstructures and nanostructures (100) consisting of a substrate (110), an array of pillars (120) capped by metallic disc (130), metallic dots (clusters or granules) (140) disposed on the...
US20090041669 Light-Emitting Biomarker  
The invention concerns novel 1,2-dioxetane derivatives of general formula (I) as defined in the description, capable of emitting a detectable luminescent signal, their use in a method for...
US20130137128 METHOD OF ASSESSING CHEMICALS IN PRODUCED FLUIDS  
A method of monitoring water-soluble treatment chemicals in a fluid that is immiscible with water and which may or may not contain some aqueous fluid, the method using at least one reagent that...
US20120009615 DIPYRROMETHENE-BORON HYDROPHILIC FLUORESCENT COMPOUNDS  
Dipyrromethene-boron hydrophilic fluorescent compounds The invention concerns fluorescent and hydrophilic compounds meeting following formula (I): wherein: S1 is a group of formula —C≡C-L′-A where...
US20110217698 METHOD TO IMPROVE SINGLE MOLECULE ANALYSES  
The quality of information from single molecule analyses is improved by employing a method in which a single molecule reaction carried out within an optical confinement is monitored, the single...
US20070224659 Harmful Substance Evaluating Method and Harmful Substance Evaluation Kit  
A biological growth inhibition factor assay method includes: a first step of mixing a photosynthetic sample, with an aqueous solution sample to prepare a test measurement solution, letting the...
US20120135459 NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES  
The present invention relates to novel fluorinated 3,6-diaminoxanthene compounds derived from the basic structural formula (I) and to their uses as photostable fluorescent dyes, e.g. for...
US20110104815 CONJUGATED NANOPARTICLES AND THEIR USE IN DETECTION OF LATENT FINGERPRINTS  
Novel conjugates of nanoparticles are provided and have particular utility in the detection of latent fingerprints by their ability to bind to a fingerprint residue. The conjugate comprises a...
US20110003398 ASSAY DEVICE COMPRISING SERIAL REACTION ZONES  
An analysis device having at least one sample addition zone, at least one sink, and at least one flow path connecting the at least one sample addition zone and the at least one sink. The at least...
US20100022022 FLUOROGENIC HOMOGENEOUS BINDING ASSAY METHODS AND COMPOSITIONS  
Disclosed are binding substrate compositions, methods and kits useful for, among other things, detecting and/or characterizing binding interactions between molecules of interest.
US20070224695 Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use  
The present invention describes a bioconjugation strategy and compounds that are useful therein in which a fluorescent signal is produced when two molecular or supramolecular entities are linked...
US20050059158 Method of performing an assay, apparatus therefor, and a method of manufacturing and apparatus  
The invention relates to a method of performing a fluorescence assay. According to the invention a filter is integrated with at least one component chosen from i) a body comprising a well, wherein...
US20080227128 Resonance Energy Transfer System and Method  
The present invention relates to a novel BRET system. The BRET system can be used to identify modified recognition sites within a protein insert and to identify the compounds involved in...
US20140242717 METHOD AND APPARATUS FOR OPTICAL DETECTION OF BIO-CONTAMINANTS  
A method and apparatus for optical detection of residual soil on articles (such as medical instruments and equipment), after completion of a washing or a rinsing operation by a washer. A soil...
US20090258441 METHOD OF PROVIDING PARTICLES HAVING BIOLOGICAL-BINDING AREAS FOR BIOLOGICAL APPLICATIONS  
The present invention includes micro-sphere composition, methods of making binding assays. The present invention also includes a micro-sphere for binding biological molecules without pretreatment....
US20110059533 FLUORESCENCE DETECTION SYSTEM, METHOD, AND DEVICE FOR MEASURING BIOMOLECULES  
A fluorescence detection system for measuring biomolecules is disclosed, which includes a fluorescence detection device, a light source, a sample-loading unit, and an analysis-reading device. The...
US20100075434 Method for detecting target substance, and tag, DNA, vector, probe and detection kit for use therewith  
Provide is a method for detecting a target substance, which method can visualize the expression of the target substance at any time point while reducing influences on the functions of the target...
US20080085566 Emissive compositions with internal standard and related techniques  
The present invention provides materials, devices, and methods related to determination of an analyte. In some embodiments, an analyte may be determined by monitoring, for example, a change in an...
US20130102088 Fluorescent Sensor and Methods  
Binding an analyte can cause a change in fluorescence emission of a sensor. The change in fluorescence can be related to the amount of analyte present. The sensor can include a semiconductor...
US20090181463 DEVICE AND METHOD FOR CHEMICAL, BIOCHEMICAL, BIOLOGICAL AND PHYSICAL ANALYSIS, RE-ACTION, ASSAY AND MORE  
The invention is directed to a device and a method for carrying out experiments of chemical, biochemical, biological and physical analysis, reaction and assay employing a reaction unit, in a...