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US20110002904 |
SYNOVIAL VILLI FOR USE WITH TISSUE ENGINEERING
Synovial villi derived explants and related surgical tools used to repair or prevent damage to injured or diseased tissue, including connective tissue. The tools including a harvesting tool for...
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US20110281338 |
NITRATE-REMOVING BIOREACTOR, METHOD FOR FORMING NITRATE-REMOVING BIOFILM, AND NITRATE-REMOVING METHOD
Disclosed is a bioreactor which is capable of efficiently removing nitrate ions. A nitrate-removing bioreactor (1) comprises a reaction container (2) and an introduction part (3) for introducing a...
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US20120029074 |
CONTROLLING TRANSGENE EXPRESSION ACROSS THE SKIN
The invention relates to the use of a skin permeating compound such as phloretin for controlling transgene expression under control of the Pseudomonas putida DOT-T1E-derived bacterial repressor...
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US20130029371 |
DISK DIFFUSION ASSAY FOR ORITAVANCIN
The present invention is directed to a disk diffusion assay for determining susceptibility of bacteria to a glycopeptide antibiotic. The assay includes improvements over conventional assays due to...
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US20100310586 |
IDIOTYPIC VACCINE
The invention concerns the use of recombinant clonotypic immunoglobulins (Ig) as a vaccine in the treatment of HCV-related and non HCV-related lymphoproliferations, in particular the use of...
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US20110117131 |
Production of OspA for Lyme Disease Control
The present invention relates, generally, to the production of one or more OspA proteins in plant cells. Heterologous DNA comprising genes encoding one or more desired OspA protein(s) are...
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US20130116343 |
Salivary Protein Markers for Detection of Breast Cancer
A method of diagnosing a patient's risk of breast cancer comprises measuring in a saliva sample from the patient a concentration of at least a first protein marker, wherein the first protein marker...
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US20110171654 |
Allelic ladder loci
Disclosed are rare short tandem repeat (STR) alleles within the D10S1248 and D12S391 loci in humans. Provided are representative allelic ladders for each locus, methods and assays using these...
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US20120204287 |
VIRAL BASED TRANSIENT-EXPRESSION VECTOR SYSTEM THAT ALLOWS MULTIPLE APPLICATIONS
Disclosed herein are viral vectors suitable for transfection into woody trees for purposes of delivering and expressing beneficial genes. Specifically exemplified herein are vectors for...
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US20120115154 |
REFERENCE MARKERS FOR BIOLOGICAL SAMPLES
DNA oligomers comprising sequences that are absent from the genome of one or more organisms of interest are used as reference markers (RMs). The RMs are added to biological samples to “tag” and sub...
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US20130005005 |
Modified Lipids Produced from Oil-Bearing Microbial Biomass and Oils
Chemically modified lipids and methods for their preparation are provided.
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US20120028879 |
HIGHLY SENSITIVE DETECTION METHOD FOR HIGHLY VIRULENT ORAL CAVITY BACTERIA
Provided is a method that involves the detection of protein antigen (PA) and/or collagen-binding protein (CBP) of oral cavity bacteria in a sample, and in which oral cavity bacteria that exacerbate...
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US20130096052 |
PROCALCITONIN FOR THE DIAGNOSIS OF BACTERIAL INFECTIONS AND GUIDANCE OF ANTIBIOTIC TREATMENT IN PATIENTS WITH NON-SPECIFIC COMPLAINTS
The present invention relates to the determination of the level of marker peptides in a sample derived from a bodily fluid of a subject presenting with non-specific complaints.
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US20110033879 |
DIRECT ASSAY OF CHOLESTEROL IN SKIN REMOVED BY TAPE STRIPPING
Skin cholesterol is measured by applying an adhesive tape onto a selected area of the skin to adhere the tape to the selected skin area and stripping the tape off the selected skin area to obtain a...
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US20120276145 |
EXTRACELLULAR MATRIX PROTEINS FROM HAEMOPHILUS INFLUENZAE BIOFILMS: TARGETS FOR THERAPEUTIC OR DIAGNOSTIC USE
A method of identifying a biofilm that includes non-typeable Haemophilus influenza (NTHi) including a step of screening a sample for the presence of one or more biofilm-specific proteins that are...
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US20110059445 |
MUCOSAL GENE SIGNATURES
Infliximab (IFX) is an effective treatment for Crohn's disease (CD) and ulcerative colitis (UC) not responding to standard therapy. Thirty percent to forty percent of patients however do not...
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US20120021470 |
Chimeric PUFA Polyketide Synthase Systems and Uses Thereof
Disclosed are chimeric polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) proteins and chimeric PUFA PKS systems, including chimeric PUFA PKS proteins and systems derived from...
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US20120315638 |
Moisture-Activated Self-Heating Analysis Device
Provided are disposable, moisture-activated, self-heating cartridges useful for, e.g., isothermal nucleic acid amplification, incubation, and thermal actuation, and visual fluorescent detection of...
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US20110171315 |
Oral recombinant helicobacter pylori vaccine and preparing method thereof
The invention relates to a recombinant protein used for immunoprophylaxis of human Helicobacter pylori infection and a degradable slow-releasing microsphere-encapsulated oral vaccine preparation...
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US20110305777 |
DIMERIC IAP ANTAGONISTS
Smac mimetics that inhibit IAPs.
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US20120021497 |
HYDRODYNAMIC EXTRACTION OF OILS FROM PHOTOSYNTHETIC CULTURES
The presently described invention relates to the method of extraction of oils from photosynthetic cultures using hydrodynamic cavitation technology for the production of biofuels or other products....
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US20130052673 |
USE OF ENZYME EMULSION THICKNESS TO AFFECT CALIBRATION CODE FACTORS IN TEST STRIP MANUFACTURING
The invention provides a method of controlling the slope, intercept and bias for a batch of test strips by increasing or decreasing the enzyme pad height of the strips. The invention provides an...
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US20130005608 |
YEAST SCREENS FOR TREATMENT OF HUMAN DISEASE
Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are provided...
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US20110300533 |
Yeast Screens for Treatment of Human Disease
Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are provided...
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US20110206765 |
Non-Typeable Haemophilus Influenzae Vaccines and Their Uses
Provided are non-typeable Haemophilus influenzae vaccines useful for the treatment of chronic obstructive pulmonary disease and asthma in a patient. In certain aspects, the vaccine is a...
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US20110104669 |
METHOD TO PREDICT IRIS COLOR
The invention comprises a method to predict iris color of a human from a nucleic acid/protein sample comprising assaying for one or more polymorphisms in the region 5′ proximal of the OCA2 gene u...
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US20110034347 |
Signatures Associated with Rejection or Recurrence of Cancer
Methods and tools for assessing the prognosis for patients following treatment of primary tumors are provided. The methods involve identifying immune-related genetic markers whose differential...
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US20100311041 |
PCR DIAGNOSTICS OF DERMATOPHYTES AND OTHER PATHOGENIC FUNGI
Dermatophytes which belong to one of the three genera Epidermophyton, Trichophyton and Microsporum are the main cause of fungal infections of skin, hair and nails. Traditional diagnostic procedures...
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US20120094292 |
FORENSIC IDENTIFICATION
The invention provides allelic ladder mixtures and individual alleles suitable for use in such mixtures. The allelic ladder mixtures give improved identification and distinguishing capabilities,...
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US20110269128 |
FORENSIC IDENTIFICATION
The invention provides allelic ladder mixtures and individual alleles suitable for use in such mixtures. The allelic ladder mixtures give improved identification and distinguishing capabilities,...
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US20100330559 |
FORENSIC IDENTIFICATION
The invention provides allelic ladder mixtures and individual alleles suitable for use in such mixtures. The allelic ladder mixtures give improved identification and distinguishing capabilities,...
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US20110045477 |
HUMAN SKIN EXPLANT CULTURE SYSTEM AND USE THEREFOR
The present invention features a human skin explant culture system and uses thereof.
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US20120263752 |
Herpes Simplex Virus Vaccines
The present invention is directed to Herpes simplex-2 viruses that may be used in vaccines to immunize patients against genital herpes.
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US20110263487 |
Plant Production and Delivery System for Recombinant Proteins as Protein-Flour or Protein-Oil Compositions
The present invention relates to a plant flour material comprising a ground, dried plant material, wherein the plant material contains a recombinant protein comprises a bactericidal or an...
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US20120225454 |
SYNTHETIC OPERON
The present invention relates to synthetic operons. In particular, the present invention relates to a synthetic operon for integration into a bacterial chromosome of a bacterium comprising a...
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US20120149594 |
BIOMARKERS FOR PREDICTION OF BREAST CANCER
The invention provides gene expression profiles (GEPs), protein expression profiles (PEPs) as well as gene/protein expression profiles (GPEPs) and methods for using them to identify those patients...
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US20110021370 |
SALIVARY PROTEIN BIOMARKERS FOR HUMAN ORAL CANCER
The present invention relates to the identification of novel oral cancer and periodontal disease biomarkers. Further, the present invention provides novel methods of diagnosing and for providing a...
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US20130065310 |
USE OF ENDOGENOUS PROMOTERS TO EXPRESS HETEROLOGOUS PROTEINS
The present invention provides methods for using endogenous transcriptional control systems to regulate the expression of heterologous protein(s). In particular, targeted genome editing is used to...
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US20130079296 |
METHOD FOR ASSAYING LOWER RESPIRATORY TRACT INFECTION OR INFLAMMATION
The present invention relates to a reliable method of prediction of lower respiratory tract infection or inflammation in humans, wherein the level of pancreatic stone protein/regenerating protein...
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US20120231453 |
Brownian Microbarcodes for Bioassays
An encoded microparticle carrying a spatial code is provided; and a set of encoded microparticles are provided with distinguishable spatial codes, wherein the codes comply with a pre-determined...
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US20130058891 |
Kexin-Derived Vaccines to Prevent or Treat Fungal Infections
A vaccine is disclosed that promotes CD4+ T cell-independent host defense mechanisms to defend against infection by fungi such as Pneumocystis spp. The vaccine may be used to prevent or to treat...
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US20110027811 |
ASSAY SYSTEM FOR THE ASSESSMENT OF ONCOGENICITY, TUMOR PROGRESSION, AND TREATMENT EFFICACY
Systems and kits are provided which are capable of determining the oncogenicity of a cancer, tumor progression, and effectiveness of a cancer treatment. Such systems and kits utilize assays to...
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US20120028261 |
PROTEIN BIOMARKERS FOR SOFT TISSUE DISEASE DIAGNOSIS AND AS THERAPEUTIC TARGETS FOR ORAL CARE INTERVENTION
Methods for identifying compounds useful for treating diseases or conditions of the oral cavity are described herein.
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US20110207177 |
SUGAR PRODUCTION PROCESS AND ETHANOL PRODUCTION PROCESS
The present invention provides a pretreatment method which enables the promotion of the enzymatic glycosylation of lignocellulose under relatively mild conditions by using a tree bark as a raw...
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US20130085268 |
MEANS FOR THE TRANSIENT PRODUCTION IN PLANTS OF RECOMBINANT PROTEINS THAT CAN BE USED IN PARTICULAR IN PROPHYLAXIS AND IN THERAPEUTICS
The invention provides a composition for the inoculation in a plant of agrobacteria transfected by expression vectors, in order to produce in said plant a protein of interest or a derivative of...
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US20110212162 |
LYMPHATIC ZIP CODES IN TUMORS AND PRE-MALIGNANT LESIONS
Disclosed herein are compositions and methods for and involving selectively targeting tumor lymphatics.
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US20120204276 |
METHODS RELATED TO A MUTATION IN COMPLEMENT FACTOR H-RELATED PROTEIN 5 IN PATIENTS WITH GLOMERULONEPHRITIS
The invention relates to methods of regulating complement. In particular, the inventors have identified a relationship between a particular gene, CFHR5, and irregularities in complement regulation....
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US20100313307 |
PROTEIN PRODUCTION AND STORAGE IN PLANTS
A transgenic dicotyledonous plant having a deficiency of one or more plant seed storage proteins, further having a transgenic polynucleotide construct comprising an open reading frame operably...
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US20130059328 |
PRODUCTION OF ENTERITIS EVOKING CAUSAL FACTOR BY HIGHLY PATHOGENIC ORAL BACTERIA AND HIGH SENSITIVITY DETECTION METHOD THEREFOR
Disclosed is the construction of a system capable of quickly and easily identifying patients having a risk for worsening inflammatory digestive tract disease by identifying a causal factor for the...
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US20130071842 |
Hypermethylation Biomarkers for Detection of Head and Neck Squamous Cell Cancer
Differentially methylated oral squamous cell carcinoma (OSCC) biomarkers, identified in-vitro and validated in well-characterized surgical specimens, have shown poor clinical correlation in cohorts...
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