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US20110287053 Recombinant Foot and Mouth Disease Vaccine  
A foot and mouth disease virus (FMDV) vaccine and method for producing same is described wherein the N terminal portion of the FMDV polyprotein, encoding the four structural proteins, 1A, 1B, 1C,...
US20140010885 SELF-ASSEMBLING NANOPARTICLE DRUG DELIVERY SYSTEM  
A self-assembling nanoparticle drug delivery system for the delivery of various bioactive agents including peptides, proteins, nucleic acids or synthetic chemical drugs is provided. The...
US20110136146 BIOASSAY FOR POLYQ PROTEIN  
The present invention relates to bioassays for mutated polyQ protein associated with disease and their use as diagnostic tools, for monitoring disease progression or for monitoring the efficacy of...
US20130059286 CRYOPRESERVATION OF UMBILICAL CORD TISSUE FOR CORD TISSUE-DERIVED STEM CELLS  
A method of preserving an umbilical cord is disclosed. The method comprises obtaining a segment of an umbilical cord; mincing the segment of the umbilical cord into cord tissue pieces; admixing the...
US20140272922 ORGAN/TISSUE DISSECTION BASIN SYSTEM  
A basin system is provided comprising a basin, a tissue supporting plate, a platform ring and a suspension rod, the basin system configured to permit a single clinician to effectively and...
US20140221621 SINGLE-CHAIN MULTIVALENT BINDING PROTEIN COMPOSITIONS AND METHODS  
Provided are protein, nucleic acid, and cellular libraries of single chain multivalent binding proteins (e.g., scDVD and scDVDFab molecules) and methods of using these of these libraries for the...
US20130237475 SYNTHETIC GENE FOR EXPRESSING SM-14 IN PICHIA PASTORIS, METHODS FOR PRODUCING AND PURIFYING SM-14 AND THE USE THEREOF AS A VACCINE AND DIAGNOSTIC MEDIUM  
The present invention pertains to the field of production of recombinant proteins, using a synthetic gene for increased expression of the protein in Pichia pastoris. More specifically, the...
US20140045193 METHIONINE METABOLITES PREDICT AGGRESSIVE CANCER PROGRESSION  
The invention relates to the use of enzymes and nanorods to detect cysteine level in a patient sample and relates to the use of the detected cysteine level to predict cancer recurrence in the...
US20120171757 CARTRIDGE AND SENSOR-DISPENSING INSTRUMENT  
A disposable cartridge adapted to be used with a sensor-dispensing instrument comprises a housing, test sensors, a mechanical mechanism and moveable seals. The housing forms at least one opening...
US20110183863 PROTEIN SCREENING METHODS  
The invention provides methods and compositions useful for identifying polypeptides with desired characteristics in vitro.
US20130150599 Production of DHA and Other LC-PUFAs in Plants  
The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase...
US20130315954 METHOD FOR IMPROVING THE PRODUCTION OF INFLUENZA VIRUSES AND VACCINE SEEDS  
The present invention relates to a method for improving the production of an influenza virus, and in particular influenza vaccine seeds, or a vaccine directed against an influenza virus,...
US20120315671 EXPRESSION MEDIA FOR PROTEINS IN YEAST SYSTEM  
The subject invention provides advantageous new media formulations, methods for their production, methods for cultivating cells using the media as well as compositions thereof and their use for...
US20130064828 Chimeric Vaccine for Haemophilus Influenzae-Induced Disease  
The invention described herein relates to a chimeric protein comprising the NTHi twitching pilus major subunit protein (PilA) presenting a portion of the NTHi OMP P5 protein. The invention provides...
US20110081357 Chimeric Vaccine for Haemophilus Influenzae-Induced Disease  
The invention described herein relates to a chimeric protein comprising the NTHi twitching pilus major subunit protein (PilA) presenting a portion of the NTHi OMP P5 protein. The invention provides...
US20110223240 COMPOUNDS FOR REVERSING AND INHIBITING PROTEIN AGGREGATION, AND METHODS FOR MAKING AND USING THEM  
The invention provides compositions for increasing the clearance of protein aggregates, and pharmaceutical compositions comprising them, and methods for making and using them, including methods for...
US20120142033 METHOD FOR EXTRACTION AND PURIFICATION OF RECOMBINANT PROTEINS FROM TRANSGENIC PLANTS  
Extraction and purification of recombinant proteins rendered difficult to extract from transgenic plants by using an extraction solution containing reducing agents and surfactants or an extraction...
US20120177675 Chimaeric Protein  
The present invention provides a chimaeric coronavirus S protein which is based on an S protein from a coronavirus strain with restricted tissue tropism, but which comprises at least part of the S2...
US20120244528 Susceptibility Genes for Age-Related Maculopathy (ARM) on Chromosome 10q26  
Allelic variations in the genes PLEKHA1 and LOC387715 are identified herein as risk factor for Age Related Maculopathy (ARM). A method is therefore provided for identifying a risk of development of...
US20130109085 Closed Photobioreactor System For Continued Daily In Situ Production Of Ethanol From Genetically Enhanced Photosynthetic Organisms With Means For Separation And Removal Of Ethanol  
The invention provides a device for growing genetically enhanced aquatic photoautotrophic organisms in a stable culture, causing the organisms to produce ethanol, and then separating, collecting,...
US20130109084 Closed Photobioreactor System For Continued Daily In Situ Production Of Ethanol From Genetically Enhanced Photosynthetic Organisms With Means For Separation And Removal Of Ethanol  
The invention provides a device for growing genetically enhanced aquatic photoautotrophic organisms in a stable culture, causing the organisms to produce ethanol, and then separating, collecting,...
US20140065710 METHODS TO CONTROL PROTEIN HETEROGENEITY  
The instant invention relates to the field of protein production, and in particular to compositions and processes for controlling and limiting the heterogeneity of proteins expressed in host cells.
US20110319472 METHODS OF PROGNOSTICATING AND TREATING EWING SARCOMA/PNET AND OTHER NEOPLASMS  
A method of distinguishing between Ewing sarcoma patients having a good prognosis relative to those having a poor prognosis by screening for specific genomic copy number alterations (CNA) isolated...
US20130052712 SURFACE IMMOBILIZATION OF VARIOUS FUNCTIONAL BIOMOLECULES USING MUSSEL ADHESIVE PROTEIN  
The present invention relates to technology of immobilizing or coating various functional bioactive substances on various surfaces without physical chemical treatment using mussel adhesive protein....
US20130116191 TRANSPORT PROTEIN WHICH IS USED TO INTRODUCE CHEMICAL COMPOUNDS INTO NERVE CELLS  
The invention relates to a transport protein which can be obtained by modifying the heavy chain of the neurotoxin formed by Clostridium botulinum. The protein binds specifically to nerve cells with...
US20110092949 IMMUNOISOLATION PATCH SYSTEM FOR CELLULAR TRANSPLANTATION  
An immunoisolation patch system, and particularly a patch system comprising multiple immunoisolation microcapsules, each encapsulating biological material such as cells for transplantation, which...
US20140273025 SYSTEM AND METHOD FOR DETERMINING RISK OF PRE-ECLAMPSIA BASED ON BIOCHEMICAL MARKER ANALYSIS  
A method for predicting risk of pre-eclampsia in a pregnant individual includes measuring one or more biochemical markers including an RBP4 biochemical marker in a blood sample obtained from the...
US20140255361 ESTROGEN-RECEPTOR BASED LIGAND SYSTEM FOR REGULATING PROTEIN STABILITY  
Disclosed herein are systems, methods and compositions for rapidly and reversibly destabilizing a target protein in vitro or in vivo, in the presence or absence of a cell-permeable, synthetic...
US20110081715 Single layer plastic test sample culture bottle  
A bottle for culturing a test sample, e.g., blood, includes a plastic vessel made from a single layer of plastic material. The bottle features a glass barrier coating applied to the bottle, such as...
US20110269149 METHOD FOR QUANTIFICATION OF BODY INTERNAL CONCENTRATION OF PROTEIN-BASED DRUG  
It is an object of the invention to provide a method for rapid and accurate quantification of a sample in the human body of a patient. The invention relates to a method for quantification of the...
US20140065670 Expression System  
A perfect palindrome operator sequence-based protein expression system is provided. The expression system comprises a promoter; and a perfect palindrome operator sequence, wherein the promoter is...
US20110213132 PRODUCTION OF NGF IN PLANT  
The invention relates to genetically modified plants capable of producing a human recombinant protein Nerve Growth Factor, either in the form of pre-pro-protein or in the mature form and parts and...
US20120264138 METHOD FOR DIAGNOSING AND MONITORING CARDIAC ISCHEMIA IN PATIENTS WITH ACUTE CHEST PAIN AND WITHOUT MYOCARDIAL INFARCTION  
The present disclosure relates to a method for diagnosing the ischemic state in a subject suffering from acute coronary syndrome who does not fulfilling the diagnostic criteria for a myocardial...
US20110105343 Systems Biology Approach Predicts Immunogenicity of Vaccines  
A major challenge in vaccinology is to prospectively determine vaccine efficacy. Disclosed herein are methods and compositions for identifying early expression “signatures” that predicted imm...
US20140273217 PRODRUG ACTIVATION IN CANCER CELLS USING MOLECULAR SWITCHES  
The present invention features a novel protein engineering strategy by combining the domains of two independent proteins into a molecular switch. The invention features polypeptides comprising a...
US20110135620 PRODRUG ACTIVATION IN CANCER CELLS USING MOLECULAR SWITCHES  
The present invention features a novel protein engineering strategy by combining the domains of two independent proteins into a molecular switch. The invention features polypeptides comprising a...
US20130295630 METHOD OF PRODUCING ETHANOL  
A method of producing ethanol wherein feedstock is broken down and mixed with yeast in a fermenting tank at an optimum predetermined temperature. An alcohol additive is added to the mixture in the...
US20120009610 ENDOSTATIN AS A MARKER OF HEART FAILURE  
Disclosed is a method for assessing heart failure in an individual including the steps of a) measuring in a sample obtained from the individual the concentration of the marker endostatin, of b)...
US20140073604 Ladder-Frame Polyether Conjugates  
Disclosed are compounds that are conjugates of ladder frame polyether compounds and biologically active compounds or research compounds, pharmaceutical formulations comprising the conjugates, and...
US20120077778 Ladder-Frame Polyether Conjugates  
Disclosed are compounds that are conjugates of ladder frame polyether compounds and biologically active compounds or research compounds, pharmaceutical formulations comprising the conjugates, and...
US20140134148 Brucella Abortus Proteins and Methods of Use Thereof  
Compositions and methods for the diagnosis and prevention of B. abortus infection are provided.
US20110177127 Brucella Abortus Proteins and Methods of Use Thereof  
Compositions and methods for the diagnosis and prevention of B. abortus infection are provided.
US20120128709 EXPRESSION OF RECOMBINANT PROTEINS  
The invention provides auto-inducible systems for expressing recombinant proteins of interest which take advantage of elements of quorum sensing (QS) systems of certain bacteria. These systems can...
US20140220018 BIOMARKERS FOR EPITHELIAL CANCER DIAGNOSIS AND TREATMENT  
Disclosed herein are methods for diagnosing the state of an epithelial tumor or tissue in a subject. Also disclosed are methods of diagnosing tumor initiation in an epithelial tissue of a subject....
US20120328591 METHODS FOR IMPROVING ORAL DELIVERY  
The invention provides a method of improving the oral delivery of a therapeutic agent, comprising the step of linking the therapeutic agent to a carrier protein comprising angiogenin, fusion...
US20140329792 SYNTHETIC CATALASE/SUPEROXIDE DISMUTASE MIMETICS AND METHODS FOR TREATING VIRAL INFECTIONS  
The invention provides for the treatment of disorders related to viral infection, using salen manganese compounds.
US20130089526 Methods for Using Synthetic Triterpenoids in the Treatment of Bone or Cartilage Diseases or Conditions  
The present invention features the use of a synthetic triterpenoid to induce gene expression and differentiation of stem or progenitor cells in the treatment of bone/cartilage diseases or conditions.
US20110236921 CELL SYSTEM  
The present invention relates to cellular systems for testing drug candidates and for evaluating the function of mitochondrial proteins. The invention is particularly useful for evaluating drug...
US20120129152 Diagnostic method for the prediction of the development of and control over the effectiveness of treatment of cardiovascular illnesses  
A diagnostic method for the prediction of the development and control of the effectiveness of the treatment of cardiovascular diseases, in which patient tissue samples are taken, microassay are...
US20120295256 WEIGHT MANAGEMENT GENETIC TEST SYSTEMS AND METHODS  
Disclosed herein is a nutritional genomic weight management algorithm running on a computer system, and more specifically, a nutritional genomic weight management algorithm where an analysis of a...