Match Document Document Title
US20120315638 Moisture-Activated Self-Heating Analysis Device  
Provided are disposable, moisture-activated, self-heating cartridges useful for, e.g., isothermal nucleic acid amplification, incubation, and thermal actuation, and visual fluorescent detection of...
US20110306097 Multiwell plate and lid  
The present invention relates to a multiwell plate for amplification and a lid with a foil for sealing the multiwell plate, wherein two positions of said lid on said plate exist, one position for...
US20110132760 Nucleic Acid Marker Ladder for Estimating Mass  
The invention relates to a nucleic acid marker ladder which is a restriction endonuclease digest, wherein a nucleic acid restriction endonuclease digest is a collection of nucleic acid fragments...
US20110118131 METHODS AND MATERIALS FOR TARGETED MUTAGENESIS  
The present disclosure relates to methods and materials for mutagenesis, including for the generation of novel or improved proteins and libraries or arrays of mutant proteins or nucleic acids...
US20110306503 TEMPLATE-DEPENDENT NUCLEIC ACID POLYMERIZATION USING OLIGONUCLEOTIDE TRIPHOSPHATES BUILDING BLOCKS  
A novel use of a template-dependent polymerase. The novel use is effected by employing the template-dependent polymerase for incorporating at least one oligonucleotide triphosphate onto a nascent...
US20110217712 EMULSION CHEMISTRY FOR ENCAPSULATED DROPLETS  
System, including methods, apparatus, compositions, and kits, for making and using a stabilized emulsion. A method of generating a stabilized emulsion is provided. In the method, an aqueous phase...
US20110033842 Skin Sampling Kit Which Stores Nucleic Acids In Stable Status, Genetic Test Methods By Using The Kit And Their Practical Application  
The present invention relates to a new skin gene card for genetic test, a method for acquiring DNA and RNA and performing various genetic tests using the same, and practical applications thereof....
US20110104693 QUANTITATIVE NUCLEASE PROTECTION SEQUENCING (qNPS)  
The present invention provides a new approach, quantitative Nuclease Protection Sequencing (qNPS™), for addressing several challenges that face sequencing and which provides improvements for...
US20120058516 SEALING MULTIWELL PLATES  
The present invention relates to a heat sealable member comprising a sheet of heat sealable material to a multiwell plate, wherein the sheet is mounted in a frame, and wherein said frame is sized...
US20130143205 HIGHLY SENSITIVE METHOD FOR DETECTION OF VIRAL HIV DNA REMAINING AFTER ANTIRETROVIRAL THERAPY OF AIDS PATIENTS  
Methods for detecting polynucleotides, especially the DNA replicated from samples obtained from subjects infected with pathogenic viruses such as human immunodefiency virus, by detecting...
US20110027774 HIGHLY SENSITIVE METHOD FOR DETECTION OF VIRAL HIV DNA REMAINING AFTER ANTIRETROVIRAL THERAPY OF AIDS PATIENTS  
Methods for detecting polynucleotides, especially the DNA replicated from samples obtained from subjects infected with pathogenic viruses such as human immunodefiency virus, by detecting...
US20110039304 Methods to Generate Oligonucleotide Pools and Enrich Target Nucleic Acid Sequences  
Methods and compositions for generating oligonucleotide pools are provided. Methods and compositions for enriching target nucleic acid sequences are also provided.
US20120227120 HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM  
Provided are hydrolases, including lipases, saturases, palmitases and/or stearatases, and polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides....
US20110277046 HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM  
Provided are hydrolases, including lipases, saturases, palmitases and/or stearatases, and polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides....
US20100316991 HUMAN PARAINFLUENZA VIRUS TYPE 3 EXPRESSING THE ENHANCED GREEN FLUORESCENT PROTEIN FOR USE IN HIGH-THROUGHPUT ANTIVIRAL ASSAYS  
Disclosed herein is a recombinant human parainfluenza virus expressing the enhanced green fluorescent protein. Methods of making and methods of using a recombinant human parainfluenza virus...
US20130065244 METHOD FOR PRODUCING cAMP USING CHIMERIC OLFACTORY RECEPTOR  
A method for producing cAMP using a chimeric olfactory receptor. The method includes a step of preparing a reaction system comprising a first layer, a lipid bilayer membrane, and a second layer,...
US20150218609 EMULSION SYSTEMS AND EMULSION-BASED AMPLIFICATION OF NUCLEIC ACID  
Methods for efficient and high throughput emulsion-based nucleic amplification are provided. In some aspects, emulsion mixtures are provided that require extremely low input energy (e.g., the...
US20130274135 COMPOSITIONS OF TOEHOLD PRIMER DUPLEXES AND METHODS OF USE  
Provided herein are primers and primer systems having improved specificity and kinetics over existing primers, and methods of use thereof.
US20140308673 METHODS FOR NUCLEIC ACID MANIPULATION  
A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing...
US20140234910 METHODS FOR NUCLEIC ACID MANIPULATION  
A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing...
US20140178941 METHODS FOR NUCLEIC ACID MANIPULATION  
A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing...
US20130330776 METHODS FOR NUCLEIC ACID MANIPULATION  
A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing...
US20130330775 METHODS FOR NUCLEIC ACID MANIPULATION  
A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing...
US20130323792 METHODS FOR NUCLEIC ACID MANIPULATION  
A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing...
US20130143274 METHODS FOR NUCLEIC ACID MANIPULATION  
A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing...
US20130143273 METHODS FOR NUCLEIC ACID MANIPULATION  
A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing...
US20130137146 METHODS FOR NUCLEIC ACID MANIPULATION  
A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing...
US20130137145 METHODS FOR NUCLEIC ACID MANIPULATION  
A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing...
US20110086353 Identification of MicroRNAs (miRNAs) in Fecal Samples as Biomarkers for Gastroenterological Cancers  
A simple, rapid, inexpensive, and promising commercial biomarker assay method for multiple diseases is described herein. The present invention detects miRNA-based biomarkers in human stool...
US20130164789 System and Methods for Making and Processing Emulsions  
An automated template bead preparation system is provided and includes a membrane-based emulsion generation subsystems, a thermal plate and subsystem, and a continuous centrifugation emulsion...
US20140065112 COMPOSITIONS AND METHODS FOR MESENCHYMAL/STROMAL STEM CELL REJUVENATION AND TISSUE REPAIR BY ENHANCED CO-EXPRESSION OF TELOMERASE AND MYOCARDIN  
A major risk factor for ischemic heart disease is advanced age. In adult bone marrow and other tissues, the number and function of stem cells decline with aging. Telomerase reverse transcriptase...
US20120077730 Method for in Vitro Molecular Evolution of Protein Function  
The invention provides a method for generating a polynucleotide sequence or population of sequences from parent polynucleotide sequences, the method comprising the steps of (a) providing a...
US20120058478 MULTIMERS OF S. SOLFATARICUS SINGLE-STRANDED DNA-BINDING PROTEIN AND METHODS OF USE THEREOF  
The invention provides multimers of S. solfataricus ssDNA binding protein that bind single stranded DNA. The multimers are robust and stable reagents for use in PCR and other techniques for...
US20130183670 METHOD FOR PRODUCING NUCLEIC ACID PROBES  
The present disclosure provides nucleic acid probes, as well as kits that include such probes. Methods for producing and using (for example in chromosomal in situ hybridization) the probes are...
US20150132804 Instruments And Method Relating To Thermal Cycling  
The present invention relates to a device for thermal cycling of biological samples, a heat sink used in such a device and a method. The heat sink comprises a base plate designed to fit in a good...
US20110195459 Methods of Making Libraries of Nucleic Acids Using Porous Particles  
The invention provides particle compositions having applications in nucleic acid analysis. Nucleic acid polymer particles of the invention allow polynucleotides to be attached throughout their...
US20060252069 PCR FOR MRSA SCCMEC TYPING  
A multiplex PCR assay for the detection, identification and classification of SCCmec types and sub-types of Staphylococcal aureus has been described.
US20130072390 Methods for Synthesizing Pools of Probes  
Compositions, methods and kits are disclosed for synthesizing and amplifying pools of probes using precursor oligonucleotides. In some aspects the precursor is amplified and nicking enzymes are...
US20140030761 METHOD OF CLONING NUCLEIC ACID  
The present disclosure provides methods for producing expression constructs comprising linking a plurality of unlinked nucleic acids, including nucleic acid encoding a marker protein.
US20130143745 COMPOSITIONS AND METHODS FOR IDENTIFYING THE ESSENTIAL GENOME OF AN ORGANISM  
Compositions and methods are provided for the rapid and highly accurate identification of the entire essential genome of any organism under a given selection condition at a resolution of a few...
US20140186894 ISOLATED DNA POLYMERASES, KITS AND APPLICATIONS THEREOF  
Isolated DNA polymerase and the mutant DNA polymerases thereof are provided. The DNA polymerases have good thermostability.
US20120122699 Methods and Oligonucleotide Designs for Insertion of Multiple Adaptors Employing Selective Methylation  
Aspects described and claimed herein provide methods to insert multiple DNA adaptors into a population of circular target DNAs at defined positions and orientations with respect to one another....
US20110046094 METHODS AND COMPOSITIONS FOR IDENTIFYING AND TREATING LUPUS  
A unique set of genetic variations associated with lupus are provided. Also provided are methods for detecting such genetic variations and for assessing risk of developing lupus as well as for...
US20100304442 METHODS, COMPOSITIONS AND KITS FOR THE IMPROVED DETECTION OF SMALL RNA MOLECULES  
The present invention provides compositions, methods and kits for use in the detection of small RNA sequences, which allow for rapid and robust amplification and detection. The methods provide...
US20140113294 DIRECT NUCLEIC ACID AMPLIFICATION KIT, REAGENT AND METHOD  
The present invention relates to compositions, methods and kits which can be used to amplify nucleic acids with the advantage of decreasing user time and possible contamination. The dried reagent...
US20140356870 METHOD FOR TRANSCRIPTIONAL AMPLIFICATION OF NUCLEIC ACIDS COMBINING STEPS OF DIFFERENT TEMPERATURES  
A method of transcriptional amplification includes: (a) obtaining a mixture by combining (i) a biological sample comprising nucleic acids, (ii) amplification primers, (iii) amplification reagents...
US20110020824 METHODS AND COMPOSITIONS FOR QUANTITATIVE AMPLIFICATION AND DETECTION OVER A WIDE DYNAMIC RANGE  
Disclosed are compositions and methods for making differentiable amplicon species at unequal ratios using a single amplification system in a single vessel. The number of differentiable amplicons...
US20110097722 Cold Shock Protein Compositions and Methods and Kits for the Use Thereof  
The present invention provides cold shock protein-containing compositions for improved DNA synthesis reactions with improved reactivity, methods for synthesizing DNA using such compositions, kits...
US20140328931 NUCLEIC ACID PARTICLES, METHODS AND USE THEREOF  
The present invention provides, among other things, a particle which includes a core comprised of self-assembled one or more nucleic acid molecules, the core being characterized by an ability to...
US20120122159 PCR-BASED METHOD OF SYNTHESIZING A NUCLEIC ACID MOLECULE  
There is provided a method of synthesizing a nucleic acid molecule and in one aspect, the method comprises assembling a full length template nucleic acid molecule by PCR in a PCR reaction mixture...