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US20130012471 MEANS AND METHODS FOR PRODUCING ARTIFICIAL CAPSULAR POLYSACCHARIDES OF NEISSERIA MENINGITIDIS  
The invention provides for an in vitro method for producing capsular polysaccharides of Neisseria meningitidis. The invention also provides capsular polysaccharides obtainable by the methods...
US20110033896 METHOD FOR MANUFACTURING AN AQUEOUS GLUCOSE SOLUTION FROM PLANTS OF THE TRITICEAE SPECIES  
The present invention relates to a method for manufacturing an aqueous glucose solution from the starch components of Triticeae grains, for example from rye, triticale or in particular wheat...
US20120263648 RNA NANOPARTICLES AND NANOTUBES  
The instant invention provides polyvalent RNA nanoparticles comprising RNA motifs as building blocks that can form RNA nanotubes. The polyvalent RNA nanoparticles are suitable for therapeutic or...
US20140287461 METHOD FOR PRODUCING SUGAR LIQUID  
A method of producing a sugar liquid using a cellulose-containing biomass as a raw material includes (a) hydrolyzing a cellulose-containing biomass to produce an aqueous sugar solution and (b)...
US20140220638 ALGAL MUTANTS HAVING A LOCKED-IN HIGH LIGHT ACCLIMATED PHENOTYPE  
Mutant photosynthetic microorganisms having reduced chlorophyll and increased photosynthetic efficiency are provided. The mutants have a locked in high light-acclimated phenotype, in which many of...
US20130059332 METHOD FOR THE PRODUCTION OF AN AQUEOUS GLUCOSE SOLUTION  
The present invention relates to a process for the production of an aqueous glucose solution from maize or maize kernels. The invention also relates to a glucose solution obtainable by this...
US20100016250 TOLL-LIKE RECEPTOR 9 AGONISTS  
The present invention provides TLR9 agonists comprising, as an active ingredient, a compound represented by formula (I): (wherein a represents 0 or 1; n represents an integer of 0 to 2; m...
US20140193388 Modified Phosphatases  
The invention relates to phosphatases and more in specific to (genetically) modified phosphatases, pharmaceutical compositions comprising (genetically) modified phosphatases and the use of...
US20140356912 CELL-BASED PRODUCTION OF NONULOSONATES  
The present invention relates to the the cell-based production of bacterial nonulosonates and their biosynthetic precursors. Specifically, the present invention provides recombinant cells for the...
US20110229931 Engineering intracellular sialylation pathways  
Methods for manipulating carbohydrate processing pathways in cells of interest are provided. Methods are directed at manipulating multiple pathways involved with the sialylation reaction by using...
US20150183838 BIOMASS PRODUCTIVITY REGULATOR  
The disclosure generally relates to methods and materials for modulating cell productivity. In particular, the present disclosure provides polynucleotides and polypeptides that when overexpressed...
US20110300582 Corynebacteria Strain Having Enhanced 5'-Xanthosine Monophosphate Productivity and a Method of Producing 5'-Xanthosine Monophosphate Using the Same  
Disclosed is a novel microorganism which has a malate dehydrogenase activity higher than that of a wild-type. Also, a recombinant vector which has the structure shown in the cleavage map of FIG....
US20060240535 Carbonyl reductase from lactococcus lactis  
Compositions and methods of using a carbonyl reductase from Lactococcus lactis (LLCR or LL-CR) are provided. One aspect provides an isolated polypeptide from Lactococcus lactis, wherein the...
US20090162892 Fermentative production of fine chemicals  
The invention relates to a process for the production of at least one microbial metabolite having at least 3 carbon atoms or at least 2 carbon atoms and at least 1 nitrogen atom by means of...
US20100159523 Coryneform Bacteria Which Produce Chemical Compounds I  
The invention relates to coryneform bacteria which have, in addition to at least one copy, present at the natural site (locus), of an open reading frame (ORF), gene or allele which codes for the...
US20130078229 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER  
The present invention is directed toward the delivery of toxic agents to pathogenic cells, particularly cancer cells. In some embodiments, the toxic agent is a human ribonuclease or similar agent...
US20120142061 Recombinant Colwellia Psychrerythraea Alkaline Phosphatase and Uses Thereof  
A heat labile alkaline phosphatase enzyme and methods of using the same and kits including the same are disclosed. Specifically, a nucleotide sequence of, peptide sequence of, methods of using,...
US20090226571 Fermentative Production of Non-Volatile Microbial Metabolism Products in Solid Form  
The present invention relates to a method for the production of at least one nonvolatile microbial metabolite in solid form by sugar-based microbial fermentation, in which process a microorganism...
US20130065270 Non-Recombinant Saccharomyces Strains that Grow on Xylose  
The present invention relates to methods for producing Saccharomyces strains that are capable of growth on xylose as a sole carbon source at a desired growth rate, (such as at least one generation...
US20050176110 Process for chromatographic separation of nucleosides  
The invention relates to a process for chromatographic separation and purification of natural and synthetic nucleosides, deoxynucleosides and corresponding bases by using cross-linked xylose...
US20050042736 High molar succinate yield bacteria by increasing the intracellular NADH availability  
The invention relates to increasing the yield of succinate in bacteria by increasing the intracellular availability of cofactors such as NADH.
US20100255544 CORYNEFORM BACTERIA WHICH PRODUCE CHEMICAL COMPOUNDS II  
The invention relates to coryneform bacteria which, instead of the singular copy of an open reading frame (ORF), gene or allele naturally present at the particular desired site (locus), have at...
US20150232502 Novel Neisseria gonorrhoeae therapeutic based on CMP-nonulosonate sugars  
N. gonorrhoeae has become resistant to almost every conventional antibiotic. Described herein is the use of CMP-nonulosonate analogues to counter gonococcal complement evasion. The nonulosonate...
US20070212759 Production Of 2'-Deoxynucleosides And 2'-Deoxynucleoside Precursors From 2-Dehydro-3-Deoxy-D-Gluconate  
This invention relates to a process for preparing 2′-deoxynucleoside compounds or 2′-deoxynucleoside precursors using 2-dehydro-3-deoxy-D-gluconic acid (usually abbreviated as KDG) or its salts as...
US20090288219 Method of Production of Recombinant Sucrose Synthase, Use Thereof in the Manufacture of Kits for Determination of Sucrose, Production of Adpglucose and Production of Transgenic Plants Whose Leaves and Storage Organs Accumulate High Contents of Adpglucose and Starch  
Method of production of recombinant sucrose synthase, use thereof in the manufacture of kits for determination of sucrose, production of ADPglucose and production of transgenic plants whose leaves...
US20130245102 NOVEL DNA TEMPLATES FOR SMALL RNA PRODUCTION IN MAMMALIAN CELLS  
This disclosure describes unique single stranded DNA templates having a characteristic sequence and secondary structure. The DNA templates disclosed herein are useful for making small RNA...
US20080241888 Method for Producing Purine Nucleosides and Nucleotides by Fermentation Using Bacterium Belonging to the Genus Bacillus or Escherichia  
Methods for producing purine nucleosides, and purine nucleotides, such as inosine and 5′-inosinic acid are provided which include using a bacterium belonging to the genus Bacillus or to the genus...
US20060263859 Method for preparing 3'-amino-2',3'-dideoxyguanosine  
Disclosed therein is a method for preparing the 3′-amino-2′,3′-dideoxyguanosine, comprising the steps of: (a) treating 3′-amino-3′-deoxythymidine and 2,6-diaminopurine with a pyrimidine nucleoside...
US20080254509 NUCLEOTIDYL TRANSFERASES WITH ENHANCED NUCLEOTIDE TRIPHOSPHATE FLEXIBILITY  
The present invention provides mutant Rm1A enzymes possessing an increased purine/pyrimidine bias in nucleotide triphosphate substrate specificity as compared to a corresponding non-mutated Rm1A...
US20100196964 METHOD FOR THE PRODUCTION OF AN AQUEOUS GLUCOSE SOLUTION  
The present invention relates to a process for the production of an aqueous glucose solution from maize or maize kernels. The invention also relates to a glucose solution obtainable by this...
US20090075342 Metabolic profile directed aptamer medicinal chemistry  
The present invention provides materials and methods for enhancing aptamers. More specifically, the materials and methods of the present invention are directed toward the modification of aptamers...
US20080299606 Fermentative Production of Organic Compounds  
A process for the fermentative production of at least one organic compound having at least 3 C atoms or having at least 2 C atoms and at least one 1 N atom, comprising the following steps: a1)...
US20080318278 Ammonia-Specific 5'-Xmp Aminase Mutant  
Disclosed herein are ammonia-specific 5′-XMP aminase mutants and a method for preparing the same. A mutation is introduced into the active site of glutamine-dependent catalysis in 5′-XMP aminase....
US20090269812 METHOD OF PRODUCING CHEMICAL PRODUCT AND CONTINUOUS FERMENTATION APPARATUS  
The invention provides a method of producing a chemical product through continuous fermentation which includes filtering a culture of a microorganism or cultured cells with a separation membrane...
US20070065922 Biocatalytic synthesis of aminodeoxy purine N9-beta-D-nucleosides containing 3-amino-3-deoxy-beta-D-ribofuranose, 3-amino-2,3-dideoxy-beta-D-ribofuranose, and 2-amino-2-deoxy-beta-D-ribofuranose as sugar moieties  
Purine N9-β-D-nucleosides containing 3-amino-3-deoxy-β-D-ribofaranose, 3-amino-2,3-dideoxy-β-D-ribofuranose, and 2-amino-2-deoxy-β-D-ribofuranose as sugar moieties are synthesized by biocatalytic...
US20110207179 PROCESS FOR PRODUCING CMP-N-ACETYLNEURAMINIC ACID  
The present invention is directed to a process for producing CMP-N-acetylneuraminic acid (CMP-NeuAc), characterized in that the process includes adding yeast cells, N-acetylglucosamine-6-phosphate...
US20080299620 Escherichia Strain Capable of Converting Xmp to Gmp and Maintaining the Inactivated State of Gene(s) Associated with Gmp Degradation and Methods of Using the Same  
Provided are mutant strains derived from Escherichia sp. GPU1114 (Accession No. KCCM-10536), having cumulative inactivation of deoD, aphA, appA, and hprt genes, and methods of using the same.
US20100330616 NOVEL ENDORIBONUCLEASE  
A polypeptide having a novel endoribonuclease activity; a nucleic acid encoding the polypeptide; recombinant DNA having the nucleic acid therein; a transformant transformed with the recombinant...
US20080213754 Method of Amplifying Atp and Use Thereof  
The ATP amplification method of the present invention is a method for amplifying and detecting a very trace amount of exogenous ATP by allowing a fusion protein (PPK-ADK) of a polyphosphate kinase...
US20090018327 SUGAR CHAIN CONTAINING 4-POSITION HALOGENATED GALACTOSE AND APPLICATION THEREOF  
The present invention is directed to, for example, an oligosaccharide having at an end thereof a 4-position halogenated galactose residue represented by formula (I): (wherein X represents a...
US20110287488 NOVEL N-ACETYLGLUCOSAMINE-2-EPIMERASE AND METHOD FOR PRODUCING CMP-NEURAMINIC ACID USING THE SAME  
The present invention relates to a novel N-acetylglucosamine-2-epimerase and a method for preparing CMP-N-acetylneuraminic acid, more specifically, relates to a N-acetylglucosamine-2-epimerase...
US20090069239 Use of Iridoptin to Induce Toxicity in Insects  
Improved methods and compounds to control insects, involving a biological control method to induce toxicity in targeted insects using iridoptin. The present invention induces high levels of...
US20090226919 METHOD FOR CONSTRUCTING AN OPERON CONTAINING TRANSLATIONALLY COUPLED GENES  
The present invention provides a method for constructing recombinant translationally coupled operons, a method for producing useful metabolites using the bacterium containing the coupled operons,...
US20060240529 Process for the preparation of fludarabine phosphate from 2-fluoroadenine and fludarabine phosphate salts with amines or ammonia  
The invention provides a process for the preparation of fludarabine phosphate from 2-fluoroadenine and 9-β-D-arabinofuranosyl-uracil using Enterobacter aerogenes (EBA). 2-Fluoroadenine is reacted...
US20100279356 PRODUCTION OF SIALYLATED N-GLYCANS IN LOWER EUKARYOTES  
The present invention relates to eukaryotic host cells which have been modified to produce sialylated glycoproteins by the heterologous expression of a set of glycosyltransferases, including...
US20150140561 COMPOUND FOR SEQUENCING BY SYNTHESIS  
The present invention provides deoxynucleoside tri- or tetraphosphate comprising a 3′ nitrate and a detectable label covalently bound to the oxygen atom of an oxymethyl or oxyallyl or oxypropargyl...
US20100279355 BETA 1,3-N-ACETYL-D-GALACTOSAMINE TRANSFERASE PROTEIN, NUCLEIC ACID ENCODING THE SAME AND METHOD OF EXAMINING CANCERATION USING THE SAME  
The N-acetyl-D-galactosamine transferase protein of the present invention is characterized by transferring N-acetyl-D-galactosamine to N-acetyl-D-glucosamine with β1,3 linkage, and it preferably...
US20150225758 GENETICALLY MODIFIED CELLS AND METHODS FOR MAKING ACTIVATED SUGAR-NUCLEOTIDES  
This disclosure generally relates to genetically engineered cells and methods of making and using such genetically engineered cells. Generally, the genetically engineered cells exhibit an increase...
US20130004979 GLYCOSYLTRANSFERASE REVERSIBILITY FOR SUGAR NUCLEOTIDE SYNTHESIS AND MICROSCALE SCANNING  
The present invention generally relates to materials and methods for exploiting glycosyltransferase reversibility for nucleotide diphosphate (NDP) sugar synthesis. The present invention provides...
US20090148559 Process for the production of compositions containing ribonucleotides and their use as flavouring agents  
The present invention describes a process to produce a composition containing 5′-ribonucleotides wherein a microorganism is subjected to autolysis under conditions at which a substantial part of...

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