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US20110076702 |
RECOMBINANT 12-KDA PROTEIN USEFUL FOR THE DETECTION OF RESPIRATORY ALLERGIES
The present invention discloses the detection of an important 12K-Da protein having cross-reactivity amongst different prevalent allergenic grasses and fungi can be useful for detection of...
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US20060257958 |
Magnetically-assisted test strip cartridge and method for using same
The present invention provides a small (business card-sized) disposable mesofluidic or microfluidic plastic cartridge containing several straight microchannels potentially filled with culture...
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US20110059858 |
NEW BIOMARKER FOR DIAGNOSIS, PREDICTION AND/OR PROGNOSIS OF SEPSIS AND USES THEREOF
The present invention provides kits and methods for the diagnosis, prognosis and prediction of sepsis in a subject using the expression level of the TREML-1 biomarker as an indication of the...
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US20120034604 |
USE OF BASIC PROLIN-RICH LACRIMAL GENE PRODUCTS, SUCH AS OPIORPHIN, AS A BIOMARKER
The present invention relates to the use of Basic Prolin-rich Lacrimal protein (BPLP) gene products, such as Opiorphin, for establishing a prognosis, a diagnosis or the monitoring of a pathological...
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US20080118911 |
Test Device for the In-Vitro Diagnosis of Multi-Analyte Tests and Use Thereof
The present invention generally relates to the diagnosis of diseases and in particular novel methods and devices for an improved use of markers that are associated with diseases to be diagnosed....
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US20110065135 |
LIPOSOME COMPOSITION, ITS PRODUCTION PROCESS, AND METHOD FOR ANALYZING ANALYTE USING THE SAME
A liposome composition capable of including a chemical substance such as an electrochemiluminescent substance in an internal aqueous phase of the liposome at a higher concentration, and a...
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US20080160545 |
Pro-GRP as a surrogate marker to predict and monitor response to Bcl-2 inhibitor therapy
A method for classifying cancer patients as eligible to receive cancer therapy with a Bcl-2 inhibitor comprising determination of the presence or absence in a patient tissue sample of levels of...
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US20080102451 |
Companion diagnostic assays for endothelin receptor antagonists
Methods for identifying cancer patients eligible to receive endothelin receptor antagonist therapy and for monitoring patient response to endothelin receptor antagonist therapy comprise assessment...
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US20060240480 |
Use of GFAP for identification of intracerebral hemorrhage
The present invention relates to the use of glial fibrillary acidic protein (GFAP) as a diagnostic marker for intracerebral hemorrhage. The invention especially relates to methods for the early...
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US20050186647 |
Methods for identifying or monitoring a patient with increased risk of cardiovascular calcification
The present invention includes novel methods of using a calcification risk index (CRI) for identifying or monitoring a patient with increased risk of cardiovascular calcification and/or mortality,...
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US20070141655 |
Multi symptom medical test to diagnose causes of vaginitis
The present invention provides methods and apparatuses for a multi symptom test system. The multi symptom test apparatus having a plurality of zones for testing a plurality of conditions comprises...
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US20120094308 |
KIT AND METHOD FOR THE PREMORTEM IN VITRO DETECTION OF ALZHEIMER'S DISEASE
Kit and method for the pre mortem in vitro detection of Alzheimer's disease The invention relates to a detection kit for Alzheimer's disease based on the vitro identification of the presence of...
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US20110306070 |
MAGNETIC BEADS FOR REDUCING LEUKOCYTE INTERFERENCE IN IMMUNOASSAYS
Methods and devices for reducing interference from leukocytes in an analyte immunoassay are provided. In one embodiment, a method is provided comprising the steps of amending a biological sample...
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US20110275536 |
BIOMARKER FOR DIAGNOSIS, PREDICTION AND/OR PROGNOSIS OF ACUTE HEART FAILURE AND USES THEREOF
The application discloses Quiescin Q6 as a new biomarker for acute heart failure; methods for predicting, diagnosing and/or prognosticating acute heart failure based on measuring said biomarker;...
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US20090317844 |
DIAGNOSTIC TEST FOR HEPATOCELLULAR CARCINOMA
A diagnostic test for hepatocellular carcinoma is based on increases in the concentration of two biochemical markers in a biological sample, alpha-1-acid glycoprotein (AAG) or isoforms thereof and...
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US20070184507 |
Methods for predicting outcome in traumatic brain injury
The invention describes methods for predicting outcome for patients suffering from traumatic brain injury (TBI) by evaluating levels of markers commonly associated with cellular damage in bodily...
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US20120034632 |
TWO-PHASE OPTICAL ASSAYS FOR ANALYTES OF NO INTRINSIC OPITCAL CONTRAST
Methods and kits for performing a two-phase optical assay for one or more than one analyte without intrinsic optical contrast in a sample are disclosed. The method requires use of a functionalized...
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US20120076774 |
DETECTION AND/OR TREATMENT OF DISEASES ASSOCIATED WITH AUTOANTIBODIES
The present invention provides a method for detecting autoantibodies to osteoprotegerin (OPG). The method comprises the step of providing a biological sample from a subject with, or at risk of...
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US20050158812 |
Kits and methods for autoantibody detection
An immunoassay method and test kit for detecting autoantibody in a patient sample, such as autoantibodies that interferes with the complexation of intrinsic factor with vitamin B12. A labeled...
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US20080241864 |
EIA for monitoring legionella pneumophila presence in water samples
A qualitative and quantitative EIA for detecting L. pneumophila in water samples is disclosed. Critical to the disclosed levels of sensitivity of these EIA's is the use of antigen-specific...
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US20110256147 |
DIAGNOSTIC AND TREATMENT METHODS FOR CANCER BASED ON IMMUNE INHIBITORS
Methods of diagnosis and treatment of malignant tumors, in particular ovarian tumors, using GD3 and GD3 inhibitors. Also provided are methods of modulating the immune system of a mammal by the...
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US20100047831 |
DIAGNOSIS OF ANTHRAX INFECTION BY DETECTION OF CAPSULAR ANTIGEN IN URINE
The present invention provides methods useful for diagnosis of anthrax by detection of capsular polypeptide in serum, urine, or other biological samples.
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US20090068692 |
MARKER FOR PROLONGED RUPTURE OF MEMBRANES
The present invention relates to amniotic fluid specific polypeptide and a method for detecting rupture of the amniotic membranes. In particular the invention provides a marker for prolonged...
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US20110015087 |
DETECTION OF ENDOMETRIAL SECRETION MARKERS FOR ASSESSMENT OF ENDOMETRIOSIS
The present invention refers to a group of biomarkers and to non-invasive in vitro methods for the diagnosis or prognosis of endometriosis, as well as to a kit to perform said methods.
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US20060105411 |
Method of detecting early pregnancy at high accuracy by measuring hCG and hyperglycosylated hCG concentrations equally
The present invention relates to methods for analyzing concentrations of hyperglycosylated hCG (H-hCG) and hCG equally in blood, serum or urine samples, preferably urine samples, from female...
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US20100172833 |
METHODS AND COMPOSITIONS FOR DIAGNOSING HEPATOCELLULAR CARCINOMA
Methods for the diagnosis of hepatocellular carcinoma (HCC) are set forth. Improved assay methods and scanning methods are included that employ non-cell-associated and cell-associated HCC related...
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US20050239150 |
Method for diagnosing sepsis by determining anti-asialogangliside antibodies
The invention relates to a method for the early detection and detection, the progression prognosis and the evaluation of the degree of severity, and the treatment-accompanying progression...
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US20110245342 |
3,5,3'-TRIIODOTHYRONINE SULFATE AS THYROMIMETIC AGENT AND PHARMACEUTICAL FORMULATIONS THEREOF
The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of...
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US20060275852 |
Assays based on liquid flow over arrays
Cassette (50) performs assays, e.g. multiplexed protein biomarker assays. Wide, bubble-free, slow flows are produced from liquids stored on cassette (50), flowing over wide array (20) of ligand...
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US20100159491 |
H-FABP AS EARLY PREDICTOR OF MYOCARDIAL INFARCTION
The present invention relates to a method for diagnosing myocardial infarction in a subject who suffers from acute coronary syndrome and has a cardiac troponin level which is detectable but lower...
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US20090123415 |
DIAGNOSIS, TREATMENT, AND PREVENTION OF VASCULAR DISORDERS USING IL-1 AUTOANTIBODIES
Methods of detecting individuals at risk for atherosclerosis and related vascular diseases involving the detection of IL-1α autoantibodies, as well as therapeutic methods to prevent or treat ...
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US20050214883 |
Novel alanine transaminase enzyme and methods of use
A novel alanine transaminase gene (ALT2) is isolated from human tissue. ALT2 specific polynucleotides, polypeptides, and antibodies are described. ALT2 is expressed predominately in liver, kidney,...
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US20100323377 |
BIOCHEMICAL MARKERS FOR CVD RISK ASSESSMENT
A method of bioassay for the quantification of peptide fragments comprising a neo-epitope formed by cleavage of a protein of an atherosclerotic plaque such as lumican, versican, perlecan, decorin,...
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US20060199235 |
Compositions and method for accurate early pregnancy diagnosis
The invention provides improved assays for detection of pregnancy. In the assays, pregnancy associated glycoproteins are analyzed in conjunction with progesterone analysis. The techniques of the...
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US20120009608 |
BIOMARKER FOR THE MONITORING AND PROGNOSIS OF CHRONIC MYELOPROLIFERATIVE DISORDERS
The invention provides a method for monitoring the progression of a myeloproliferative disease, particularly Polycythemia Vera (PV) and Essential Thrombocythemia (ET), or the response to...
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US20090187084 |
Flexible Carbohydrate-Bearing Polymer
A sensor for the detection or measurement of a carbohydrate analyte in fluid comprises components of a competitive binding assay the readout of which is a detectable or measurable optical signal...
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US20050260695 |
Methods, compositions, devices, and kits for detecting mastitis
The present invention includes compositions, kits and methods useful for the detection of mastitis in an animal. These agents and methods are primarily directed to a method of detecting the...
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US20090239247 |
MN and Hypoxia
The MN/CA IX protein is identified herein as a hypoxia marker. The MN/CA9 gene promoter is characterized, and the location of the HIF-1 binding site within the MN/CA9 promoter is identified....
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US20080108095 |
Microchip and Method for Detecting Molecules and Molecular Interactions
A microchip with flow-through inlet (104) and outlet (106) channels and test channels (108). The test channels (108) are in fluid communication with the inlet (104) and outlet (106) channels,...
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US20110318765 |
METHOD FOR PRE-TREATING SAMPLE CONTAINING GLYCATED HEMOGLOBIN
There are provided a pre-treatment technique for a glycated hemoglobin-containing sample, which is a simple and convenient treatment, is free from problems in storage stability and environmental...
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US20080003599 |
Biological Microchip for Multiple Parallel Immunoassay of Compounds and Immunoassay Metods Using Said Microchip
The present invention relates to biochemistry, medicine, and molecular biology, in particular to analytical biochemistry and immunochemical assay, and is concerned with a biological microchip for...
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US20110269159 |
REAGENTS FOR REDUCING LEUKOCYTE INTERFERENCE IN IMMUNOASSAYS
Methods and devices for reducing interference from leukocytes in an analyte immunoassay are provided. In one embodiment, a method is provided comprising the steps of amending a biological sample...
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US20100190192 |
METHOD OF DIAGNOSING PRE-ECLAMPSIA
The present invention relates to a marker for the development of pre-eclampsia. In particular the invention provides a marker for the development of pre-eclampsia, which marker consists of a...
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US20070184506 |
IMMUNOLOGICAL TEST ELEMENT WITH IMPROVED CONTROL ZONE
The invention concerns a test element for carrying out an immunological sandwich test for determining an analyte from a liquid sample containing a reagent zone or conjugate zone which contains a...
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US20050170446 |
Sandwich assay and kit
A sandwich assay method for detecting the presence of a target molecule in a sample comprising a complex biological fluid is provided. The assay comprises providing a first affinity ligand with...
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US20120064001 |
Anti-VEGF Antibody Compositions and Methods
Disclosed are human antibodies that specifically inhibit VEGF binding to only one (VEGFR2) of the two primary VEGF receptors. The antibodies effectively inhibit angiogenesis and induce tumor...
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US20060246526 |
Microfluidic affinity assays with improved performance
Method for measuring the signal from a label in a labeled measuring reagent that has been specifically adsorbed to its affinity counterpart in a zone of a porous nanolitre (nl) bed that is present...
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US20050130246 |
Detecting human anti-therapeutic antibodies
The invention provides a method for detecting the presence of anti-therapeutic antibody antibodies in a patient being treated with a therapeutic antibody. In one aspect of the invention, the...
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US20060240488 |
Detection of an immune response to GDF-8 modulating agents
This disclosure provides methods for the detection of antibodies to a GDF-8 modulating agent such as, e.g., MYO-029, in a biological sample. Methods to detect an immune response to a GDF-8...
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US20120009211 |
BIMER OR AN OLIGOMER OF A DIMER, TRIMER, QUADROMER OR PENTAMER OF RECOMBINANT FUSION PROTEINS
The invention relates to oligomers of a dimer, trimer, quatromer or pentamer of recombinant fusion proteins. Said oligomers are characterized in that the recombinant fusion proteins have at least...
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