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US20080176257 |
Assay for Antibodies
The presence and quantity of an antibody of interest in a patient's bloodstream or other biological sample can serve as an important clinical or other analytical or diagnostic tool. ELISA methods,...
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US20080113395 |
Methods for Diagnosing Bi-Polar Disorder
The invention relates to the use of Reelin as a marker for diagnosing psychiatric conditions. The disclosed tools and techniques can facilitate the diagnosis of psychiatric disorders including...
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US20080113394 |
Methods for Diagnosing Major Depression
The invention relates to the use of Reelin as a marker for diagnosing psychiatric conditions. The disclosed tools and techniques can facilitate the diagnosis of psychiatric disorders including...
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US20080113393 |
Methods for Diagnosing Schizophrenia
The invention relates to the use of Reelin as a marker for diagnosing psychiatric conditions. The disclosed tools and techniques can facilitate the diagnosis of psychiatric disorders including...
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US20080113392 |
ASSAYS FOR CANCER PATIENT MONITORING BASED ON LEVELS OF ANALYTE COMPONENTS OF THE PLASMINOGEN ACTIVATOR SYSTEM IN BODY FLUID SAMPLES
The present invention describes clinically and medically important methods of examining, screening over time, and monitoring the outcome of a cancer patient who is undergoing treatment or therapy...
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US20080113341 |
FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION
The invention provides novel fluorinated resorufin compounds that are of use in a variety of assay formats. Also provided are methods of using the compounds and kits that include a compound of the...
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US20080108089 |
Methods for predicting pregnancy outcome in a subject by hCG assay
The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present...
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US20080104734 |
RECOMBINANT ANTIBODIES TO SCLEROTINIA ANTIGENS
The invention is directed to recombinant antibodies which bind to Sclerotinia sclerotiorum antigens and comprise a single chain variable fragment (scFv). The antigen may be selected from SSPG1d...
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US20080096821 |
Cytostatin II
The invention relates to cytostatin II growth modulatory polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the...
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US20080096218 |
Polynucleotide Encoding a Maize Herbicide Resistance Gene and Methods for Use
This invention relates to polynucleotide sequences encoding a gene that can confer resistance to at least one herbicide. It further relates to plants and seeds of plants carrying chimeric genes...
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US20080090262 |
METHOD TO SIMULTANEOUSLY DETECT DIFFERENT ANTIBODIES AND ANTIGENS IN CLINICAL ALIMENTARY AND ENVIRONMENTAL SAMPLES
Method to simultaneously detect different antibodies and antigens via immunoenzimatic tests and ELISA (Enzyme Linked ImmunoSorbent Assay) constituted by small absorbent cylinders, on which the...
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US20080090261 |
Method For The In Vitro Diagnosis Of The Exclusion Of Acute Coronary Syndromes
The present invention relates to a method for the in vitro diagnosis of the exclusion of acute coronary syndromes (ACS), consisting in associating the quantification of the concentration of at...
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US20080090251 |
Assays For Superantigens
The present invention provides a superantigen quality control assay, particularly for SEA-E120, comprising incubating a standard amount of a superantigen-containing test sample with a standard...
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US20080085878 |
SUPEROXIDE DISMUTASE-2 EXPRESSION AND MODULATION FOR GLAUCOMA DIAGNOSIS AND THERAPY
The present invention concerns a method for diagnosing or monitoring elevated intraocular pressure or glaucoma in a patient comprising providing a biological sample from the patient and measuring...
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US20080085526 |
CLINICAL DIAGNOSIS OF HEPATIC FIBROSIS USING A NOVEL PANEL OF HUMAN SERUM PROTEIN BIOMARKERS
The inventors have proposed a novel panel of human serum protein biomarkers for diagnosing hepatic fibrosis and cirrhosis. Presently there is no reliable non-invasive way of assessing liver...
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US20080085524 |
METHODS FOR DIAGNOSING IRRITABLE BOWEL SYNDROME
The present invention provides methods, systems, and code for accurately classifying whether a sample from an individual is associated with irritable bowel syndrome (IBS). In particular, the...
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US20080085244 |
Methods for identifying and using amyloid-inhibitory compounds
The present invention relates to identification of agents that pay a role in regulating brain amyloid-β (Aβ) levels in vivo. The invention provides compounds and methods of using such compounds...
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US20080081348 |
Detection and monitoring of liver damage
A method of detecting liver damage in a subject comprises measuring the level of caspase-3 generated cytokeratin-18 fragments in the bodily sample. The level of measuring the level of caspase-3...
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US20080081339 |
Tumor associated markers in the diagnosis of prostate cancer
The invention is directed to tumor associated markers (TAMs) that can be used diagnostically, especially in the diagnosis of prostate cancer and other markers (BPHMs) that can be used in the...
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US20080076140 |
Biomarkers of Alzheimer's Disease
A test for diagnosing Alzheimer's Disease comprises measuring levels of GSK-3 in cells or body fluid in a sample taken from a human subject. The test provides a relatively noninvasive method of...
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US20080070265 |
PEPTIDE-BASED IMMUNIZATION THERAPY FOR TREATMENT OF ATHEROSCLEROSIS
The present invention relates to a fragment of apolipoprotein B, for immunization for prophylactic or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases,...
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US20080069828 |
Methods, kits, and antibodies for detecting parathyroid hormone
The present invention relates to novel methods and compositions useful for detecting whole parathyroid hormone at a physiological level and parathyroid fragments in a mammalian sample. Such...
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US20080064733 |
Small Molecule Inhibition of Pdz-Domain Interaction
Novel compounds that have been found effective in inhibiting PDZ domain interactions, and particularly interactions of PDZ domains in MAGIs with the oncogenic (tumor suppressor) protein PTEN and...
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US20080064052 |
Crystal of a Receptor-Ligand Complex and methods of use
The invention relates to the three-dimensional structure of a crystal of an EphB4 receptor complexed with a ligand. The three-dimensional structure of a Receptor-Ligand Complex is disclosed. The...
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US20080064039 |
DOMINANT NEGATIVE LIGAND DRUG DISCOVERY SYSTEM
The present invention relates to novel methods of designing and optimizing polypeptide based ligands which are useful for altering and/or modulating cellular signaling cascades which have become...
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US20080064034 |
Multi-Cellular Test Systems
The invention relates to methods for testing substances using multicellular in vitro test systems, in particular systems that resemble organs, and to devices and kits for carrying out said methods.
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US20080057524 |
Neurotransmission disorders
There is disclosed a method for diagnosing neurotransmission or developmental disorders in a mammal comprising the step of detecting in a bodily fluid of said mammal autoantibodies to an epitope of...
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US20080057523 |
Detection of Protein Aggregates by Homologous Elisa
A method of detecting disease related protein aggregate in a sample comprises using a capture monoclonal antibody and detecting-monoclonal antibody. The capture monoclonal antibody and the...
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US20080051328 |
Novel Muscle Growth Regulator
A muscle growth regulating factor includes polynucleotide and polypeptide sequences, promoter sequences, constructs comprising the sequences, and compositions for regulating muscle growth and...
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US20080038761 |
COMPOSITIONS AND METHODS FOR DETECTING AND QUANTIFYING TOXIC SUBSTANCES IN DISEASE STATES
The present invention relates to compositions comprising synthetic aggregated peptides (SAPs). The present invention also relates to the use of these SAPs as standards in methods for quantifying...
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US20080038760 |
Method for Detecting Anti-Transglutaminase Antibodies
Methods for detecting anti-transglutaminase antibodies in a saliva sample containing the antibodies are disclosed. Saliva samples are pre-treated. The antibodies are subsequently detected in the...
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US20080038730 |
Diagnostic and Therapeutic Use of Kcnj6 for Alzheimer's Disease
The present invention discloses a dysregulation of the KCNJ6 gene and the protein products thereof in Alzheimer's disease patients. Based on this finding, the invention provides a method for...
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US20080038192 |
Diagnostic Methods Of Multiple Organ Amyloidosis
Described are methods of assessing whether a subject has or is at risk of having multiple organ amyloidosis (MOA) The method includes detecting a diagnostically predictive collection of biomarkers...
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US20080032927 |
TREATMENT OF DEVELOPMENT-RELATED DISORDERS
Disclosed are composition and methods for treating development-related disorders. Also disclosed are diagnosis methods, prognosis methods, and drug screening methods.
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US20080032319 |
METHOD FOR DIAGNOSING COLON CANCER
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US20080026413 |
COMPLEXES AND METHODS
The invention relates to a cell comprising an exogenous capture moiety on its cell surface, wherein said capture moiety is capable of supporting the attachment of an HLA molecule thereto. In...
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US20080026412 |
BETA-2 MICROGLOBULIN AS A BIOMARKER FOR PERIPHERAL ARTERY DISEASE
The present invention provides β2 microglobulin as a biomarker for qualifying or assessing peripheral artery disease in a subject.
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US20080014600 |
DIAGNOSIS OF MULTIPLE SCLEROSIS AND OTHER DEMYELINATING DISEASES
A method of diagnosing multiple sclerosis and other demyelinating diseases or predicting a predisposition to multiple sclerosis and other demyelinating diseases. The method utilizes detection of...
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US20080009023 |
Diagnostic Method For The Forecasting Of Transplanted Organ Loosing
It is described a diagnostic method which allows to establish the risks of rejection of a transplanted organ by measuring the pre-transplant concentration of Mig in the serum of a patient to be...
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US20080009005 |
Detection of cancer by elevated levels of BCL-2
The present invention relates to a method for the diagnosis, prognosis, and monitoring of cancer, such as early or late stage ovarian cancer, in a subject by detecting Bcl-2 in a biological sample...
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US20080003626 |
Assay for detection of antibodies to lysosomal enzymes
The present invention relates to methods for screening body fluids or tissues for antibodies, including neutralizing and isotype-specific antibodies, against lysosomal enzymes administered as part...
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US20080003625 |
Predicting Alzheimer's Disease
This document relates to methods and materials related to determining whether or not a mammal (e.g., a human) is susceptible to develop mild cognitive impairment or Alzheimer's disease.
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