Match Document Document Title
US20120028879 HIGHLY SENSITIVE DETECTION METHOD FOR HIGHLY VIRULENT ORAL CAVITY BACTERIA  
Provided is a method that involves the detection of protein antigen (PA) and/or collagen-binding protein (CBP) of oral cavity bacteria in a sample, and in which oral cavity bacteria that...
US20130084581 Method of Identifying Transmembrane Protein-Interacting Compounds  
A method for screening compounds for their ability to interact with transmembrane proteins is provided. Also provided is a method for determining whether proteins such as transmembrane proteins...
US20100331192 SURFACE DISPLAY OF RECOMBINANT PROTEINS IN LOWER EUKARYOTES  
Methods for display of recombinant proteins or protein libraries on the surface of lower eukaryotes such as yeast and filamentous fungi are described. The methods are useful for screening...
US20110165597 METHOD FOR THE SCREENING OF CONSERVED SECRETED PROTEINS  
Conserved polypeptides from protozoan parasitic species which are secreted through the endoplasmic reticulum/Golgi dependent secretory pathway, their identification and their use.
US20110065661 PHARMACOPERONES FOR CORRECTING DISEASE STATES INVOLVING PROTEIN MISFOLDING  
This application relates to methods of identifying pharmacoperone agents that can restore function to a misfolded protein, such as a misfolded protein that causes disease. Also disclosed are...
US20110160081 FUNCTIONAL COMPLEMENTATION ASSAY FOR DEFINED GPCR OLIGOMERS  
The present invention is directed to, inter alia, a biological reagent that includes a complex having a first GPCR and a second GPCR linked to a G-protein, the linkage between the second GPCR and...
US20140106378 METHODS FOR DIAGNOSIS AND PROGNOSIS OF EPITHELIAL CANCERS  
The present invention is based on the discovery that three proteins, Cystatin B, Chaperonin 10, and Profilin are present in the urine of patients with bladder cancer, a cancer of epithelial...
US20110195431 HUMAN ORPHAN G PROTEIN-COUPLED RECEPTORS  
The invention disclosed in this patent document relates to transmembrane receptors, more particularly to endogenous, human orphan G protein-coupled receptors.
US20140302523 Small-Molecule Hydrophobic Tagging of Fusion Proteins and Induced Degradation of Same  
The present invention includes compounds that are useful in perturbing or disrupting the function of a transmembrane or intracellular protein, whereby binding of a compound to the transmembrane or...
US20120270230 MUTANT G-PROTEIN COUPLED RECEPTORS AND METHODS FOR SELECTING THEM  
The invention relates to mutant G-protein coupled receptors with increased conformational stability, and methods of use thereof. In some aspects, polynucleotides encoding the mutant G-protein...
US20130078644 Post-Translational Modifications Identified by Elemental Analysis  
Methods and kits for enzymes involved in post-translational modifications are provided. The methods employ elemental analysis, including ICP-MS. The methods allow for the convenient and accurate...
US20140147856 Intestinal Permeability Assay for Neurodegenerative Diseases  
A method of identifying a subject at risk of developing or having a neurodegenerative disorder is provided. The method includes obtaining a biological sample from the subject and assaying a level...
US20100333239 METHODS USING ACYL-COA BINDING PROTEINS TO ENHANCE LOW-TEMPERATURE TOLERANCE IN GENETICALLY MODIFIED PLANTS  
ACBP6 can be used to enhance low temperature tolerance in genetically modified plants. An acbp6 T-DNA insertional mutant that lacked ACBP6 mRNA and protein, displayed increased sensitivity to...
US20140113309 METHOD AND APPARATUS FOR ANALYZING PROTEIN-PROTEIN INTERACTION ON SINGLE-MOLECULE LEVEL WITHIN THE CELLULAR ENVIRONMENT  
A method of analyzing protein-protein interactions includes binding the first proteins to the substrate where the first proteins are tagged with the first markers which bind specifically to the...
US20140221241 Mass Dots: Nanoparticle Isotope Tags  
Compositions and methods are provided for the use of nanoparticles, which may be referred to herein as mass dots, as mass tags for probes such as antibodies, aptamers, nucleic acids, etc. in...
US20140068794 R2R1/2 In Diagnosis and Therapy  
The present invention stems from the finding that two genes designated R2R1 and R2R2, play important roles in tissue development and cancer biology. In particular, the inventors have discovered...
US20120276558 KITS FOR MULTIPARAMETRIC PHOSPHO ANALYSIS  
As disclosed herein, the present invention provides for kits and a composition for diagnosis, prognosis, drug discovery, drug development, and patient stratification. The kits can comprise a...
US20140221325 GLOMERULONEPHRITIS BIOMARKERS  
The present invention relates to methods of diagnosing glomerulonephritis (GN) in a patient, as well as methods of monitoring the progression of GN and/or methods of monitoring a treatment...
US20110165144 METHODS FOR TREATING RHEUMATOID ARTHRITIS  
Provided are methods of treating rheumatoid arthritis by inhibiting Neuromedin U signalling.
US20130011409 Compositions, Kits, and Methods for the Diagnosis, Prognosis, Monitoring, Treatment and Modulation of Post-Transplant Lymphoproliferative Disorders and Hypoxia Associated Angiogenesis Disorders Using Galectin-1  
The present invention is based, in part, on the discovery that galectin-1 (Gal1) plays a role in viral-associated PTLD, e.g., EBV-associated PTLD and hypoxia associated angiogenesis disorders....
US20150064713 METHODS, KITS AND MEANS FOR DETERMINING INTRACELLULAR INTERACTIONS  
Methods, kits and systems for determining whether a reaction occurs between a chimeric transmembrane receptor and an intracellular interaction partner thereof within a cell.
US20120159664 Transgenic Plants With Enhanced Agronomic Traits  
This invention provides recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. Also provided by this invention is...
US20110182881 SIGNATURE AND DETERMINANTS ASSOCIATED WITH METASTASIS AND METHODS OF USE THEREOF  
The present invention provides methods of detecting cancer using biomarkers.
US20110104261 REMOTE DETECTION OF SUBSTANCE DELIVERY TO CELLS  
The present invention provides for the development of endocytosis-sensitive probes, and a remote method for measuring cellular endocytosis. These probes are based on the reduced water permeability...
US20120227134 Plants with Increased Yield  
A method for producing a plant with increased yield as compared to a corresponding wild type plant whereby the method comprises at least the following step: increasing or generating in a plant or...
US20110053139 Detection of bioagents using a shear horizontal surface acoustic wave biosensor  
Viruses and other bioagents are of high medical and biodefense concern and their detection at concentrations well below the threshold necessary to cause health hazards continues to be a challenge...
US20110112177 Human G-Protein Coupled Receptor (HETGQ23)  
Human G-protein coupled receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed were...
US20110028383 Activated Forms Of Notch And Methods Based Thereon  
The present invention is directed to methods for detecting or measuring Notch activation by observing or measuring the appearance of Notch on the cell surface or by observing or measuring Notch...
US20130172205 MARKERS OF ACUTE KIDNEY FAILURE  
The present invention relates to the method of determining the risk of acute kidney injury comprising determining the amount of a marker selected from VCAN, NRP1, CCL2, CCL19, COL3A1, GZMM or any...
US20100279318 METHOD OF IDENTIFYING TRANSMEMBRANE PROTEIN-INTERACTING COMPOUNDS  
A method for screening compounds for their ability to interact with transmembrane proteins is provided. Also provided is a method for determining whether proteins such as transmembrane proteins...
US20130316366 EXPRESSION OF SECRETED AND CELL-SURFACE POLYPEPTIDES  
Some embodiments herein provide compositions and methods for expressing secreted and cell-surface-bound polypeptides in a single cell. In some embodiments, secreted and cell-surface polypeptide...
US20120164666 Glycoprotein Vesicles and Their Methods of Use  
Provided are methods of collecting, detecting and altering cells and molecular entities using glycoprotein micelles and vesicles. Glycoprotein vesicles comprising a glycoprotein micelle, at least...
US20100173788 BIOMARKERS FOR BREAST CANCER  
The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying breast cancer status in a patient. In particular, the biomarkers of this invention...
US20120003628 Methods for Diagnosing Pervasive Development Disorders, Dysautonomia and Other Neurological Conditions  
Methods for aiding in the diagnosis of disorders including, but not limited to, PDDs (Pervasive Development Disorders), Dysautonomic disorders, Parkinson's disease and SIDS (Sudden Infant Death...
US20110165087 TARGETED DELIVERY OF IMAGING PROBES FOR IN VIVO CELLULAR IMAGING  
The present invention relates to nitroxide imaging probes that are isotopically modified or unmodified. Such nitroxide imaging probes may be included in liposomes that encapsulate self-quenching...
US20110010780 KCNN3 AS DIAGNOSTIC AND THERAPEUTIC TARGET FOR NEURODEGENERATIVE DISEASES  
The present invention discloses a dysregulation of the KCNN3 gene and the protein products thereof in Alzheimer's disease patients and individuals being at risk of developing Alzheimer's disease....
US20130035258 LUMINESCENT TETRAPODS DOTS AND VARIOUS APPLICATIONS  
A tetrapod article and its uses are disclosed whereby such tetrapod article comprises an apex base nanomaterial and X leg base nanomaterial protruding from the apex, wherein X is an integer. In an...
US20120184485 USES OF CYSTATIN  
The present invention relates to uses of cystatins derived from nematodes and to a method of screening using such cystatin. The present invention also relates to methods of treatment and/or...
US20110003306 IDENTIFICATION OF ANTIBIOTIC RESISTANCE USING LABELLED ANTIBIOTICS  
Subject of the present invention is a method for detection of an antibiotic resistance in a micro-organism comprising the steps of exposing suspected micro-organism to a labelled (fluorescent)...
US20130095490 COMPOSITION FOR DIAGNOSIS OF LUNG CANCER AND DIAGNOSIS KIT OF LUNG CANCER  
Disclosed is as a biomarker useful in early diagnosis of lung cancer, at least one protein selected from the group including Quescin-sulfhydryl oxidase 1, Fibrillin-1, Isoform A of Lamin-A/C,...
US20150010903 Real Time Diagnostic Assays Using an Evanescence Biosensor  
The present invention relates to a method for the detection of a substance in an aqueous, physiological or chemical liquid using the evanescence field method, and to a diagnostic device for...
US20130052657 MEASUREMENT METHOD FOR PHYSIOLOGICALLY ACTIVE SUBSTANCE OF BIOLOGICAL ORIGIN, AND REAGENT KIT FOR MEASUREMENT  
Disclosed is a technique which simplifies the adjustment of a reagent which makes the proteins contained in limulus amoebocyte lysate (LAL) attach to the surface of microparticles dispersed in a...
US20130330278 MULTICOLORED pH-ACTIVATABLE FLUORESCENCE NANOPLATFORM  
The present invention relates to pH-tunable, highly activatable multicolored fluorescent nanoplatforms and methods of using the nanoplatforms in a variety of applications including, but not...
US20140057948 VIF AS A TARGET FOR HIV INHIBITION  
The present invention relates, e.g., to a method for inhibiting infectivity of a lentivirus (e.g., a lentivirus which expresses a Viral infectivity factor (Vif) protein), such as, e.g., SIV, SHIV...
US20130040850 SEROLOGY ASSAYS  
The invention provides methods and kits for measuring the ability of a test sample to inhibit the binding of a receptor expressed by a pathogen to a host cell ligand of the pathogen.
US20100183578 NITROPROTEIN BIOMARKERS FOR COPD  
Specific nitroprotein biomarkers may be used as prognostic and diagnostic tools for COPD. Identification of certain specific nitroprotein biomarkers allows the development of targeted therapies...
US20110177085 Bitter Taste Receptors  
The present invention relates to bitter-taste receptors and their role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or...
US20120115130 METHOD FOR DETECTING TARGET CELL  
A target cell detection method includes performing a test measurement on a dispersion to obtain a measurement result 1, the test measurement being an optical or electromagnetic measurement, and...
US20150132775 METHOD AND DEVICE FOR DETERMINING CONCENTRATION, CROSSTALK AND DISPLACEMENT FLUORESCENCE CROSS CORRELATION SPECTROSCOPY  
The present invention provides a FCCS method for determining the concentration and/or the diffusion coefficient of at least a first labeled species, a second labeled species and/or a complex...
US20110236884 MICROBUBBLES FOR AFFINITY SEPARATION  
The present invention relates to methods, compositions and kits for affinity isolation, affinity purification and affinity assay based on microbubbles coated with an affinity molecule....