|
Match
|
Document |
Document Title |
|
|
US20100297632 |
UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER
The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocyte cell of said mammal, and the deduction...
|
|
|
US20110045475 |
UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER
The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocytic cell of said mammal, and the...
|
|
|
US20110065609 |
Methods and Kits for the Diagnosis of Rheumatoid Arthritis
The present invention relates to the identification and use of proteins with clinical relevance to rheumatoid arthritis (RA). In particular, the invention provides the identity of marker proteins...
|
|
|
US20110065649 |
USE OF MULTIVALENT SYNTHETIC LIGANDS OF SURFACE NUCLEOLIN FOR TREATING CANCER OR INFLAMMATION
A method for treating disorders involving deregulation of cell proliferation and/or angiogenesis comprising the administration of an effective amount of a multivalent synthetic compound comprising...
|
|
|
US20110136146 |
BIOASSAY FOR POLYQ PROTEIN
The present invention relates to bioassays for mutated polyQ protein associated with disease and their use as diagnostic tools, for monitoring disease progression or for monitoring the efficacy of...
|
|
|
US20110269149 |
METHOD FOR QUANTIFICATION OF BODY INTERNAL CONCENTRATION OF PROTEIN-BASED DRUG
It is an object of the invention to provide a method for rapid and accurate quantification of a sample in the human body of a patient. The invention relates to a method for quantification of the...
|
|
|
US20110177127 |
Brucella Abortus Proteins and Methods of Use Thereof
Compositions and methods for the diagnosis and prevention of B. abortus infection are provided.
|
|
|
US20120003209 |
METHODS AND KITS USED IN IDENTIFYING GLIOBLASTOMA
The invention encompasses methods and kits used in the identification of invasive glioblastoma based upon the expression of Akt1, Akt2, and Akt3. The methods and kits also allow prediction of...
|
|
|
US20110008765 |
USE OF THREE-DIMENSIONAL MICROFABRICATED TISSUE ENGINEERED SYSTEMS FOR PHARMACOLOGIC APPLICATIONS
The present invention generally relates to a combination of the fields of tissue engineering, drug discovery and drug development. It more specifically provides new methods and materials for...
|
|
|
US20110212464 |
PACAP AS A MARKER FOR CANCER
The present invention relates to a method aiding in the assessment of cancer. It discloses the use of the proapoptotic caspase adaptor protein (=PACAP) as a universal marker of different types of...
|
|
|
US20110046002 |
Seven Gene Breast Cancer Predictor
The invention provides a molecular marker set that can be used for prognosis of breast cancer in a patient using histologically normal tissue. The invention also provides methods for evaluating...
|
|
|
US20100297108 |
METHOD OF PROVIDING PATIENT SPECIFIC IMMUNE RESPONSE IN AMYLOIDOSES AND PROTEIN AGGREGATION DISORDERS
A novel treatment of Alzheimer's disease and other disorders involving protein misfolding or aggregation is provided by enhancing or sustaining an antibody response against predominantly directed...
|
|
|
US20120028268 |
METHOD OF PREDICTING ACUTE APPENDICITIS
Embodiments of the invention provide method and devices for predicting the likelihood of acute appendicitis without invasive exploratory medical procedures. Several protein biomarkers: leucine-rich...
|
|
|
US20110224088 |
Biomarkers for subtypes of cervical cancer
The present invention relates to biomarkers for chemoradioresistant subtypes of cervical cancer. In particular the present invention relates to a method for predicting a predisposition to a...
|
|
|
US20110014225 |
CROSS-REACTIVE DETERMINANTS AND METHODS FOR THEIR IDENTIFICATION
Compositions and methods for determining immunologically cross-reactive molecules comprising a cross-reactive antigenic determinant are provided, in particular for determining proteins comprising...
|
|
|
US20110039276 |
IDENTIFYING ORGAN DAMAGE
The present invention provides methods for identifying whether or not a patient has, or is at risk of developing drug induced organ damage and methods of treating patients having drug induced organ...
|
|
|
US20110212465 |
ARMET AS A MARKER FOR CANCER
Disclosed is a method aiding in the assessment of cancer. More specifically disclosed is the use of the arginine-rich metastasized in early tumors protein (=ARMET) as a universal marker of...
|
|
|
US20120108523 |
DISEASE-ASSOCIATED PROTEIN
Disclosed are methods and compositions for early diagnosis, monitoring and treatment of retinal dystrophy, age-related macular degeneration, Bardet-Biedel syndrome, Bassen-kornzweig syndrome, best...
|
|
|
US20110045482 |
SCREENING METHODS FOR IDENTIFYING TARGET ANTIFUNGAL GENES AND COMPOUNDS BY DETECTING CELL SURFACE GLYCOPROTEINS
The present invention relates to an assay method that can be used for high-throughput detection of cell surface glycoproteins. Specifically, the secretion of a chimeric glycoprotein reporter...
|
|
|
US20110171661 |
METHOD FOR DIAGNOSIS OF POST-OPERATIVE RECURRENCE IN PATIENTS WITH HEPATOCELLULAR CARCINOMA
Provided are a method of diagnosing the recurrence or possibility of recurrence of hepatocellular carcinoma after hepatocellular carcinoma surgery and a method of screening a drug for preventing...
|
|
|
US20110020837 |
Method for isolating or identifying a target protein interacting with a lipid in a cell
The invention is in the field of molecular biology and cell biology. It provides tools and methods for studying the interaction of proteins and lipids in vivo as well as in vitro. The invention...
|
|
|
US20110318730 |
MICROPATTERNED CO-CULTURE SYSTEMS AS INFECTIOUS DISEASE ANALYSIS PLATFORMS
Cell cultures are provided that include a population of micropatterened hepatocytes and one or more non-parenchymal cell populations, where the hepatocytes are infected with a virus or parasite and...
|
|
|
US20120122123 |
DETECTION OF ANTHRAX PATHOGENICITY FACTORS
One major problem in diagnosis methods presently available for anthrax is that these methods require several days to produce a result. The only existing treatment for anthrax requires...
|
|
|
US20110028344 |
BIOMARKERS FOR ENDOMETRIAL DISEASE
This patent application discloses and describes a list of proteins that are found to be differentially expressed between normal endometrial epithelial cells and early stage cancerous endometrial...
|
|
|
US20120083518 |
Cancer Treatment Targeting BRCA1-IRIS
Patients identified as candidates at risk of developing aggressive cancer, including metastatic cancer, are determined based on the expression of BRCA1-IRIS. In one advantageous form, the...
|
|
|
US20120108447 |
METHODS OF PREDICTING CLINICAL OUTCOME IN MALIGNANT MELANOMA
Malignant melanoma is the most aggressive type of skin cancer and currently accounts for more than 160.000 new cancer cases worldwide every year. Incidence of malignant melanoma is rapidly...
|
|
|
US20120115161 |
COMPOSITIONS AND METHODS FOR DEMONSTRATING SECRETORY IMMUNE SYSTEM REGULATION OF STEROID HORMONE RESPONSIVE CANCER CELL GROWTH
Serum-containing and serum-free immunoglobulin inhibitors of steroid hormone responsive cancer cell growth are disclosed, along with their methods of production. Also disclosed are defined cell...
|
|
|
US20120053079 |
METHODS AND COMPOSITIONS FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER
The present invention relates to methods and compositions for diagnosing and treating cancer, such as breast cancer and skin cancer.
|
|
|
US20110280901 |
Diagnosis and treatment of Trypanosoma cruzi infection and chagas disease
Provided herein are vaccine compositions for control of Trypanosoma cruzi infection and Chagas disease. The compositions comprise plasmids encoding o GPI-anchored genes ASP-2, TcG-1, TcG2 and TcG4...
|
|
|
US20120040379 |
METHODS FOR DIFFERENTIATING PLASMA- DERIVED PROTEIN FROM RECOMBINANT PROTEIN IN A SAMPLE
The present invention relates, in general, to methods for detecting and quantitating plasma-derived protein and recombinant protein in a sample based on the difference in protein glycosylation,...
|
|
|
US20120094289 |
MATERIALS AND METHODS FOR DETERMINING CANCER RISK
This document relates to materials and methods involved in assessing inflammatory bowel disease patients at risk for developing cancer. For example, materials and methods for monitoring colorectal...
|
|
|
US20120020974 |
OPTIMIZING ERYTHROPOIETIN THERAPY
The methods described herein can be used to identify ex ante which hemodialysis patients are likely to develop EPO resistance and therefore will require additional rHu EPO, and to provide...
|
|
|
US20110206615 |
PROBE REAGENT FOR MEASURING OXIDATIVE STRESS
The present invention relates to fluorescent or luminescent probe reagents for measuring oxidative stress in a cell or an organism. Examples of the probe reagents include: a fluorescent or...
|
|
|
US20120115173 |
BIOMARKERS FOR MOTOR NEURON DISEASE
The invention provides methods of determining a diagnosis or prognosis of motor neuron disease in a mammal comprising determining the expression level of one or more proteins or polypeptides of the...
|
|
|
US20120028271 |
Methods and Kit for Detecting Breast Cancer
The present inventions relates to kits and methods for diagnosing and monitoring breast cancer. An increase in the level or activity of proteins of the ubiquitin/proteasome pathway, and ancillary...
|
|
|
US20110165146 |
METHODS OF DIAGNOSING ALZHEIMER'S DISEASE
Methods and compositions relating to Alzheimer's disease are provided. Specifically, proteins that are differentially expressed in the Alzheimer's disease state relative to their expression in the...
|
|
|
US20110159514 |
BIOMARKER FOR OSTEOARTHRITIS AND/OR OTHER AGEING-RELATED DISEASES, AND USE THEREOF
The invention relates to the identification of a biomarker whose abundance in biological sample is changed in subjects with osteoarthritis and/or other ageing-related diseases. The biomarker has...
|
|
|
US20110183341 |
Use of 14-3-3-Proteins in Treatment and Prevention of Neurodegeneration
The present disclosure is directed to methods for treatment and prevention of disease states characterized by a decreased 14-3-3 polypeptide expression or activity. In one embodiment, the present...
|
|
|
US20110124010 |
DIAGNOSTIC METHOD
A method of detecting the presence, or monitoring the severity of a condition characterised by the presence of fragments of a marker protein in the brain of a patient. The method comprises: (i)...
|
|
|
US20120004133 |
METHOD FOR THE DIAGNOSIS OF AGE-ASSOCIATED VASCULAR DISORDERS
Methods for determining if a subject has or is susceptible to having an age-associated vascular disorder are disclosed. The method includes determining if the subject exhibits altered expression of...
|
|
|
US20120040884 |
Methods and Reagents for Treatment and Diagnosis of Vascular Disorders and Age-Related Macular Degeneration
Disclosed are screening methods for determining a human subject's propensity to develop a vascular disorder and/or age-related macular degeneration (AMD), therapeutic or prophylactic compounds for...
|
|
|
US20100317040 |
METHODS AND KITS FOR DIAGNOSING CANCER
A method of diagnosing oral cancer or oral pharyngeal cancer in a subject in need thereof is provided. The method comprising determining a level or activity of at least one marker in a saliva...
|
|
|
US20100317041 |
NEURAL PROTEINS AS BIOMARKERS FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS
The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree...
|
|
|
US20110207627 |
EX VIVO THERAPEUTICS SCREENING OF LIVING BONE MARROW CELLS FOR MULTIPLE MYELOMA
Methods of selecting a treatment for a patient with multiple myeloma are provided. Prior to commencing a treatment regime, bone marrow aspirates are isolated from a patient and incubated with one...
|
|
|
US20110244486 |
METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF DIABETES
Methods, assays and compositions for the diagnosis and treatment of diabetes, in which the glutamate transporters and/or receptors expressed in pancreatic islet cells are used as therapeutic...
|
|
|
US20110003707 |
Highly Sensitive Biomarker Panels
Cardiovascular disease, e.g., congestive heart failure, is often first diagnosed after the onset of clinical symptoms, eliminating potential for early intervention. The invention provides a...
|
|
|
US20110200620 |
B7-H1 AND METHODS OF DIAGNOSIS, PROGNOSIS, AND TREATMENT OF CANCER
The invention features methods of diagnosis by assessing B7-H1 expression in a tissue from a subject that has, or is suspected of having, cancer, methods of treatment with agents that interfere...
|
|
|
US20110287958 |
Method for Using Gene Expression to Determine Colorectal Tumor Stage
The invention relates to methods of determining a colorectal tumor stage in a patient by gene expression analysis. The method comprises assaying the level of at least one RNA transcript, or its...
|
|
|
US20110230372 |
GENE EXPRESSION CLASSIFIERS FOR RELAPSE FREE SURVIVAL AND MINIMAL RESIDUAL DISEASE IMPROVE RISK CLASSIFICATION AND OUTCOME PREDICTION IN PEDIATRIC B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA
The present invention relates to the identification of genetic markers patients with leukemia, especially including acute lymphoblastic leukemia (ALL) at high risk for relapse, especially high risk...
|
|
|
US20110021635 |
RBM3 AS A MARKER FOR BREAST CANCER PROGNOSIS
The present invention provides means, such as a method, for determining whether a prognosis for a mammalian subject having a breast cancer is better than a reference prognosis. The method comprises...
|