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US20110245104 Method for screening the sensitizing properties of chemical compounds  
A method is provided for screening the sensitizing properties of chemical compounds. The method is based on keratinocytes or cells that share important hallmarks of these cells, but other...
US20110152357 Micro-RNA-Based Compositions and Methods for the Diagnosis, Prognosis and Treatment of Multiple Myeloma  
Methods for assessing a pathological condition in a subject includes measuring an expression profile of one or more markers where a difference is indicative of multiple myeloma (MM) or a...
US20110318370 CXCL4L1 AS A BIOMARKER OF PANCREATIC CANCER  
The invention relates to the use of CXCL4L1 as a biomarker of pancreatic cancer in a patient. More particularly, the invention relates to a method for detecting a pancreatic cancer and/or...
US20130017192 Diagnosis and Treatment of Autoantibody-Mediated Heart Disease  
Provided herein are, inter alia, methods of diagnosing and treating autoimmune cardiomyopathy in subjects, based upon the detection of IgG4 autoantibodies to cardiac troponin I (cTnI).
US20120003228 METHODS FOR PREDICTING AUTOIMMUNE DISEASE RISK  
The invention relates to means and methods for determining whether a subject is at high or low risk of autoimmune disease progression by determining the CD8 or CD4 cell subtype of the subject....
US20110086360 METHOD FOR DETECTION OF IDIOPATHIC INTERSTITIAL PNEUMONIA  
The present invention provides a method for detecting idiopathic interstitial pneumonia, which comprises measuring the expression level of a periostin gene or the amount of a periostin protein in a...
US20140141980 Stratifying and annotating a clinical practice guideline  
Personalized medicine involves the use of a patient's molecular markers to guide treatment regimens for the patient. The scientific literature provides multiple examples of correlations between...
US20130171662 ASSAY  
This disclosure relates to a diagnostic/prognostic assay for prostate cancer and including kits used in said assay.
US20140080136 COMPOSITIONS, KITS, AND METHODS FOR DETECTING AND ANALYZING VESICLES  
Provided are compositions, kits, and methods for detecting a vesicle comprising a membrane permeable marker that is converted into a detectable marker inside the vesicle.
US20120322048 Materials and Methods for Assessing and Mapping Microbes and Microbial Biofilms on Wounds  
The subject invention provides point-of-care assays for assessing the topographical distribution of microbial biofilm and/or specific microorganisms in wounds.
US20100330586 METHOD FOR IDENTIFYING COMPOUNDS FOR TREATMENT OF PAIN  
Methods and products for the attenuation or treatment of pain and the reduction of nociception are described. The methods and products are based on the modulation of CNS intracellular chloride...
US20130116166 BIOMARKERS FOR IDIOPATHIC PULMONARY FIBROSIS  
Biomarkers, kits, and diagnostic and treatment methods for idiopathic pulmonary fibrosis are provided.
US20120244548 Methods Of Determining Skeletal Maturity  
The present invention provides methods to determine skeletal maturity.
US20130236919 METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING MOOD DISORDERS  
The present invention relates to methods of diagnosing, prognosing or treating diseases or disorders in which elevated or reduced levels of Aβ protein, including Aβ1-42 are prevalent. In p...
US20140066360 METHODS FOR USING SEMAPHORIN POLYPEPTIDES  
The present invention provides uses and methods of using a sema3E polypeptide and a sema3e polynucleotide encoding a sema3E polypeptide. The methods include decreasing airway remodeling in a...
US20120020954 METHODS OF PREDICTING CLINICAL COURSE AND TREATING MULTIPLE SCLEROSIS  
Provided are methods and kits for classifying a subject as being more likely to have benign multiple sclerosis (BMS) or as being more likely to have typical relapsing remitting multiple sclerosis...
US20130296408 MEDULLOBLASTOMA GENES AS TARGETS FOR DIAGNOSIS AND THERAPEUTICS  
Medulloblastoma (MB) is the most common malignant brain tumor of children. To identify the genetic alterations in this tumor type, we searched for copy number alterations using high density...
US20130202577 DIAGNOSTIC AND PROGNOSTIC ASSAY FOR BREAST CANCER  
The invention relates to the finding that T cell protein tyrosine phosphatase (TCPTP) has a tumour suppressor function. In one particular application, the invention provides a method of diagnosis...
US20110136745 METHOD OF SELECTING SOYBEANS WITH ENHANCED BIOACTIVITY AND COMPOSITIONS FOR REDUCING CANCER CELL VIABILITY  
The invention provides a method that uses enzyme-treatment of whole soybeans or partially defatted soybeans to select soybeans with improved bioactivity or bioactivities. The invention further...
US20130190251 METHOD FOR PREDICTING THE RESPONSIVENESS TO CHEMOTHERAPY  
The present invention concerns a method for predicting the responsiveness of an individual suffering from leukemia to a chemotherapeutic drug. In particular, this method comprises determining the...
US20140242604 ULTRA-FAST PATHOGEN TOXIN DETECTION ASSAY BASED ON MICROWAVE-ACCELERATED METAL-ENHANCED FLUORESCENCE  
The present invention provides for a system and method to detect low levels of the anthrax protective antigen (PA) exotoxin in biological fluids, wherein the system uses a metal-enhanced...
US20120231090 MOLECULAR BIOMARKER SET FOR EARLY DETECTION OF OVARIAN CANCER  
Embodiments of the present invention concern methods and compositions related to detection of ovarian cancer, including detection of the stage of ovarian cancer, in some cases. In particular, the...
US20100304401 YS68 GENE INVOLVED IN PRIMITIVE HEMATOPOIESIS  
A novel gene, dubbed “YS68”, involved in primitive hematopoiesis was successfully isolated from cDNA derived from mouse yolk sacs. In addition, a human gene corresponding to this gene was suc...
US20110129819 DIAGNOSIS OF HEREDITARY SPASTIC PARAPLEGIAS (HSP) BY INDENTIFICATION OF A MUTATION IN THE KIAA1840 GENE OR PROTEIN  
The invention relates to an ex vivo method of diagnosing or predicting an hereditary spastic paraplegias (HSP), in a subject, which method comprises detecting a mutation in the KIAA1840 gene or...
US20110302674 Methods and Compositions for the Improvement of Plant Tolerance to Environmental Stresses  
The invention provides methods, polynucleotides and polypeptides useful for producing or selecting plants with increased tolerance to at least one environmental stress selected from drought, cold,...
US20110002949 VACCINE FOR THE TREATMENT OF ALZHEIMER'S DISEASE  
The invention provides a method for the treatment of a patient having a more severe form of Alzheimer's disease (AD), where the severe form of AD is characterized by pathogenic deposits of amyloid...
US20120142632 DIAGNOSTIC AND PROGNOSTIC ASSAY  
The present disclosure relates generally to the field of diagnostic and prognostic assays for diseases and conditions of the systemic vasculature. The present disclosure teaches an assay for...
US20120034599 SCREENING SYSTEMS UTILIZING RTP801  
RTP801 represents a unique gene target for hypoxia-inducible factor-1 (HIF-1). Down-regulation of the mTOR pathway activity by hypoxia requires de novo mRNA synthesis and correlates with increased...
US20120121505 THERAPEUTIC COMPOSITIONS AND METHODS  
The present application provides novel binding proteins, including human binding proteins that specifically bind to the human ErbB2.
US20110097710 Methods for detecting atrial fibrillation and related conditions  
Methods for detecting disorders associated with atrial fibrillation, and, thus, at risk for stroke and/or heart failure) in a subject based on a monitoring plasma levels of apelin are provided....
US20130040308 COMPOSITIONS AND METHODS FOR CHARACTERIZING A MYOPATHY  
The invention provides compositions, methods, and kits diagnosing, monitoring, and otherwise characterizing a myopathy and for detecting the presence of autoantibodies in a biological sample.
US20100297152 METHODS OF DIAGNOSIS OF PROSTATE CANCER, COMPOSITIONS AND METHODS OF SCREENING FOR MODULATORS OF PROSTATE CANCER  
Described herein are genes whose expression are up-regulated or down-regulated in prostate cancer. Also described are such genes whose expression is further up-regulated or down-regulated in...
US20120071335 Method for Identification, Selection and Analysis of Tumour Cells  
The present invention relates to a method for the diagnosis of tumoural conditions and/or of the corresponding state of advance, wherein a specimen of an organic fluid taken from the patient and...
US20110059473 PROTEINS WITH PTERIDINE GLYCOSYLTRANSFERASE ACTIVITY AND ANALYSIS METHOD USING THE SAME  
The present invention relates to proteins with pteridine glycosyltransferase activity and an analysis method using the same. Since the proteins glycate tetrahydrobiopterin selectively through an...
US20120058498 Compositions and Methods for Characterizing Arthritic Conditions  
The present invention relates to autoantibodies against 14-3-3 proteins or circulating immune complexes thereof and the detection of such for the diagnosis and prognosis of an arthritic condition.
US20120202209 CELL IMAGING METHOD FOR VIEWING MICRORNA BIOGENESIS IN THE CELLS  
The present invention relates to a method for viewing the biogenesis of at least one microRNA, preferably a microRNA group, in a living cell, characterised in that said method includes the...
US20120004254 G PROTEIN-COUPLED RECEPTOR ANTAGONIST AND ITS USE FOR PREVENTING AND TREATING ALZHEIMER'S DISEASE  
The invention discloses methods for screening a reagent for treating or preventing Alzheimer's disease or related neurological pathology. A method according to the invention includes the steps of:...
US20120178111 METHODS AND COMPOSITIONS FOR THE DETECTION OF LUNG CANCERS  
A method of screening for, diagnosing or detecting lung cancer in a subject, the method comprising: a) determining a level of a biomarker or a plurality of biomarkers in a sample from the subject,...
US20130115589 Pharmaceutical Composition for Treatment and Prevention of Herpes Virus Infections  
An object of the present invention is to find a protein expressed in a variety of cells and functioning as a receptor for herpesvirus and provide a preventive or remedy for herpesvirus infections...
US20100297631 Compositions and Methods For Detecting Histamine Related Disorders  
The present invention generally relates to methods and compositions (e.g., assay kit) for the diagnosis of histamine related disorders. The invention also relates to a novel molecular target of...
US20110212470 BIOMARKERS FOR RHEUMATOID ARTHRITIS  
The present invention relates to the diagnosis of autoimmune disorders, more specifically to the diagnosis of rheumatoid disorders, chronic autoimmune arthritis and even more specifically to the...
US20110044999 IL-32 MODULATORS  
The present invention relates to methods of screening for modulators of interleukin 32 (IL-32), to modulators of IL-32 and to their use.
US20120164666 Glycoprotein Vesicles and Their Methods of Use  
Provided are methods of collecting, detecting and altering cells and molecular entities using glycoprotein micelles and vesicles. Glycoprotein vesicles comprising a glycoprotein micelle, at least a...
US20110275542 SIGNATURES AND DETERMINANTS FOR DISTINGUISHING BETWEEN A BACTERIAL AND VIRAL INFECTION AND METHODS OF USE THEREOF  
The present invention provides methods of detecting infection using biomarkers.
US20110294123 METHODS FOR DIAGNOSING OR TREATING PROSTATE CANCER  
The present invention provides methods for detecting and/or diagnosing cancer through the determination of the expression level of the STC2 gene. The gene was discovered to discriminate cancer...
US20140080754 DIAGNOSTIC METHOD FOR BACTERIAL MENINGITIS  
It has been demonstrated that the level of HBP increases in individuals that have bacterial meningitis. Accordingly, the level of HBP in an individual can be used to determine whether or not an...
US20100105571 Protein Signature/Markers for the Detection of Adenocarcinoma  
The present invention provides a method for determining the presence of pancreatic adenocarcinoma in an individual and/or for determining the survival time of an individual afflicted with...
US20120009581 Gene Expression Profiling for Predicting the Survivability of Prostate Cancer Subjects  
A method is provided in various embodiments for determining a profile data set for predicting the survivability of a subject with prostate cancer based on a sample from the subject, wherein the...
US20110294136 BIOMARKER FOR DIAGNOSING PANCREATIC CANCER  
The invention relates to a method for diagnosing pancreatic cancer (PaCa) or the precursor diseases and/or concomitant diseases thereof, in particular pancreatic ductal adenocarcinoma (PDAC),...
US20140134165 Identification of Tumor-Associated Markers for Diagnosis and Therapy  
The present technology relates to genetic products the expression of which is associated with cancer diseases. The present technology also relates to the therapy and diagnosis of diseases in which...