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US20130202577 DIAGNOSTIC AND PROGNOSTIC ASSAY FOR BREAST CANCER  
The invention relates to the finding that T cell protein tyrosine phosphatase (TCPTP) has a tumour suppressor function. In one particular application, the invention provides a method of diagnosis...
US20110136745 METHOD OF SELECTING SOYBEANS WITH ENHANCED BIOACTIVITY AND COMPOSITIONS FOR REDUCING CANCER CELL VIABILITY  
The invention provides a method that uses enzyme-treatment of whole soybeans or partially defatted soybeans to select soybeans with improved bioactivity or bioactivities. The invention further...
US20130190251 METHOD FOR PREDICTING THE RESPONSIVENESS TO CHEMOTHERAPY  
The present invention concerns a method for predicting the responsiveness of an individual suffering from leukemia to a chemotherapeutic drug. In particular, this method comprises determining the...
US20120231090 MOLECULAR BIOMARKER SET FOR EARLY DETECTION OF OVARIAN CANCER  
Embodiments of the present invention concern methods and compositions related to detection of ovarian cancer, including detection of the stage of ovarian cancer, in some cases. In particular, the...
US20100304401 YS68 GENE INVOLVED IN PRIMITIVE HEMATOPOIESIS  
A novel gene, dubbed “YS68”, involved in primitive hematopoiesis was successfully isolated from cDNA derived from mouse yolk sacs. In addition, a human gene corresponding to this gene was suc...
US20110129819 DIAGNOSIS OF HEREDITARY SPASTIC PARAPLEGIAS (HSP) BY INDENTIFICATION OF A MUTATION IN THE KIAA1840 GENE OR PROTEIN  
The invention relates to an ex vivo method of diagnosing or predicting an hereditary spastic paraplegias (HSP), in a subject, which method comprises detecting a mutation in the KIAA1840 gene or...
US20110302674 Methods and Compositions for the Improvement of Plant Tolerance to Environmental Stresses  
The invention provides methods, polynucleotides and polypeptides useful for producing or selecting plants with increased tolerance to at least one environmental stress selected from drought, cold,...
US20110002949 VACCINE FOR THE TREATMENT OF ALZHEIMER'S DISEASE  
The invention provides a method for the treatment of a patient having a more severe form of Alzheimer's disease (AD), where the severe form of AD is characterized by pathogenic deposits of amyloid...
US20120142632 DIAGNOSTIC AND PROGNOSTIC ASSAY  
The present disclosure relates generally to the field of diagnostic and prognostic assays for diseases and conditions of the systemic vasculature. The present disclosure teaches an assay for...
US20120034599 SCREENING SYSTEMS UTILIZING RTP801  
RTP801 represents a unique gene target for hypoxia-inducible factor-1 (HIF-1). Down-regulation of the mTOR pathway activity by hypoxia requires de novo mRNA synthesis and correlates with increased...
US20120121505 THERAPEUTIC COMPOSITIONS AND METHODS  
The present application provides novel binding proteins, including human binding proteins that specifically bind to the human ErbB2.
US20110097710 Methods for detecting atrial fibrillation and related conditions  
Methods for detecting disorders associated with atrial fibrillation, and, thus, at risk for stroke and/or heart failure) in a subject based on a monitoring plasma levels of apelin are provided....
US20130040308 COMPOSITIONS AND METHODS FOR CHARACTERIZING A MYOPATHY  
The invention provides compositions, methods, and kits diagnosing, monitoring, and otherwise characterizing a myopathy and for detecting the presence of autoantibodies in a biological sample.
US20100297152 METHODS OF DIAGNOSIS OF PROSTATE CANCER, COMPOSITIONS AND METHODS OF SCREENING FOR MODULATORS OF PROSTATE CANCER  
Described herein are genes whose expression are up-regulated or down-regulated in prostate cancer. Also described are such genes whose expression is further up-regulated or down-regulated in...
US20120071335 Method for Identification, Selection and Analysis of Tumour Cells  
The present invention relates to a method for the diagnosis of tumoural conditions and/or of the corresponding state of advance, wherein a specimen of an organic fluid taken from the patient and...
US20110059473 PROTEINS WITH PTERIDINE GLYCOSYLTRANSFERASE ACTIVITY AND ANALYSIS METHOD USING THE SAME  
The present invention relates to proteins with pteridine glycosyltransferase activity and an analysis method using the same. Since the proteins glycate tetrahydrobiopterin selectively through an...
US20120058498 Compositions and Methods for Characterizing Arthritic Conditions  
The present invention relates to autoantibodies against 14-3-3 proteins or circulating immune complexes thereof and the detection of such for the diagnosis and prognosis of an arthritic condition.
US20120202209 CELL IMAGING METHOD FOR VIEWING MICRORNA BIOGENESIS IN THE CELLS  
The present invention relates to a method for viewing the biogenesis of at least one microRNA, preferably a microRNA group, in a living cell, characterised in that said method includes the...
US20120004254 G PROTEIN-COUPLED RECEPTOR ANTAGONIST AND ITS USE FOR PREVENTING AND TREATING ALZHEIMER'S DISEASE  
The invention discloses methods for screening a reagent for treating or preventing Alzheimer's disease or related neurological pathology. A method according to the invention includes the steps of:...
US20120178111 METHODS AND COMPOSITIONS FOR THE DETECTION OF LUNG CANCERS  
A method of screening for, diagnosing or detecting lung cancer in a subject, the method comprising: a) determining a level of a biomarker or a plurality of biomarkers in a sample from the subject,...
US20130115589 Pharmaceutical Composition for Treatment and Prevention of Herpes Virus Infections  
An object of the present invention is to find a protein expressed in a variety of cells and functioning as a receptor for herpesvirus and provide a preventive or remedy for herpesvirus infections...
US20100297631 Compositions and Methods For Detecting Histamine Related Disorders  
The present invention generally relates to methods and compositions (e.g., assay kit) for the diagnosis of histamine related disorders. The invention also relates to a novel molecular target of...
US20110212470 BIOMARKERS FOR RHEUMATOID ARTHRITIS  
The present invention relates to the diagnosis of autoimmune disorders, more specifically to the diagnosis of rheumatoid disorders, chronic autoimmune arthritis and even more specifically to the...
US20110044999 IL-32 MODULATORS  
The present invention relates to methods of screening for modulators of interleukin 32 (IL-32), to modulators of IL-32 and to their use.
US20120164666 Glycoprotein Vesicles and Their Methods of Use  
Provided are methods of collecting, detecting and altering cells and molecular entities using glycoprotein micelles and vesicles. Glycoprotein vesicles comprising a glycoprotein micelle, at least a...
US20110275542 SIGNATURES AND DETERMINANTS FOR DISTINGUISHING BETWEEN A BACTERIAL AND VIRAL INFECTION AND METHODS OF USE THEREOF  
The present invention provides methods of detecting infection using biomarkers.
US20110294123 METHODS FOR DIAGNOSING OR TREATING PROSTATE CANCER  
The present invention provides methods for detecting and/or diagnosing cancer through the determination of the expression level of the STC2 gene. The gene was discovered to discriminate cancer...
US20140080754 DIAGNOSTIC METHOD FOR BACTERIAL MENINGITIS  
It has been demonstrated that the level of HBP increases in individuals that have bacterial meningitis. Accordingly, the level of HBP in an individual can be used to determine whether or not an...
US20100105571 Protein Signature/Markers for the Detection of Adenocarcinoma  
The present invention provides a method for determining the presence of pancreatic adenocarcinoma in an individual and/or for determining the survival time of an individual afflicted with...
US20120009581 Gene Expression Profiling for Predicting the Survivability of Prostate Cancer Subjects  
A method is provided in various embodiments for determining a profile data set for predicting the survivability of a subject with prostate cancer based on a sample from the subject, wherein the...
US20110294136 BIOMARKER FOR DIAGNOSING PANCREATIC CANCER  
The invention relates to a method for diagnosing pancreatic cancer (PaCa) or the precursor diseases and/or concomitant diseases thereof, in particular pancreatic ductal adenocarcinoma (PDAC),...
US20140134165 Identification of Tumor-Associated Markers for Diagnosis and Therapy  
The present technology relates to genetic products the expression of which is associated with cancer diseases. The present technology also relates to the therapy and diagnosis of diseases in which...
US20110200597 SIGNAL PATHWAY ALTERATIONS AND DRUG TARGET ELEVATIONS IN PRIMARY METACHRONOUS METASTATIC COLORECTAL CANCER COMPARED TO NON-METASTATIC DISEASE  
The present invention relates to the identification and diagnostic use of biomarkers in primary colorectal cancer tumors whose activation level are predictive of the likelihood of the onset of...
US20130059751 GENE FAMILY (LBFL313) ASSOCIATED WITH PANCREATIC CANCER  
The invention relates generally to the changes in gene expression in human pancreatic adenocarcinoma. The invention relates specifically to a human gene family which is differentially expressed in...
US20120028252 HUMAN MENA ISOFORMS SERVE AS MARKERS OF EPITHELIAL TO MESENCHYMAL TRANSITION AND SENSITIVITY TO EGFR INHIBITION IN HUMAN CANCER CELLS  
The present invention discloses a method for discriminating between sensitive and resistant tumours to a treatment with EGFR inhibitor drugs comprising: in vitro testing whether tumour material...
US20120269825 METHODS OF MODULATING THE OX40 RECEPTOR TO TREAT CANCER  
Numerous disease states, such as human allergic, autoimmune, and autoimmune diseases, and cancer, may be treated by targeting OX40/OX40L. OX40L inhibits the generation of Tr1 cells from naïve and ...
US20100173788 BIOMARKERS FOR BREAST CANCER  
The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying breast cancer status in a patient. In particular, the biomarkers of this invention...
US20100086937 METHOD TO DETECT TREPONEMA PALLIDUM IMMUNOLOGICAL MARKERS FOR THE DIAGNOSIS OF SYPHILIS  
This invention discloses using SPR technology to qualitatively detect the presence of Treponema pallidum immunological markers in a serum sample, which can be used for the diagnosis of syphilis. It...
US20140072981 CYSTEINE HYDRAZIDE NICOTINAMIDE FOR GLYCOMICS AND GLYCOPROTEOMICS USES  
A cysteine hydrazide nicotinamide (Cyhn) reagent designed for the enrichment of bacterial glycoproteins is provided. Methods for purification of free oligosaccharides and their analysis are also...
US20110021367 DIAGNOSIS AND MONITORING OF MYCOBACTERIUM TUBERCULOSIS INFECTION  
Disclosed are methods for detecting protein complexes of sigma factors and interacting proteins in a sample containing Mycobacterium tuberculosis. Such methods are useful for the diagnosis and/or...
US20120058488 WIRELESS BASED MARINE PATHOGENS DETECTION SYSTEM  
Embodiments of the present Invention provide antibody functionalized high electron mobility transistor (HEMT) devices for marine or freshwater pathogen sensing. In one embodiment, the marine...
US20110082187 MARKERS AND METHODS RELATING TO THE ASSESSMENT OF ALZHEIMER'S DISEASE  
Use of clusterin as a biomarker of Alzheimer's disease (AD), particularly methods and compositions for detection of clusterin in a biological sample and assessment of in vivo pathology, disease...
US20130331281 MOLECULAR MARKERS FOR PROGNOSTICALLY PREDICTING PROSTATE CANCER, METHOD AND KIT THEREOF  
The present application provides a method for predicting clinical prognosis for a human subject diagnosed with prostate cancer, comprising: detecting an expression level of a marker gene selected...
US20110275086 NEGATIVE CORRELATION BETWEEN IRP-2 AND TRANSFERRIN RECEPTOR EXPRESSION AS A DIAGNOSTIC OF ALZHEIMER'S DISEASE  
A method of diagnosing Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) is disclosed which was identified by the fact that an increased level of iron regulating protein-2 (IRP-2) was...
US20120178095 CARDIOMYOCYTE DIFFERENTIATION  
This invention provides a method for testing a factor for cardiogenicity which comprises differentiating human embryonic stem (hES) cells to cardiomyocytes in the presence and absence of the factor...
US20050282179 Biomarkers for interferon-alpha response in hepatitis C virus infected patients  
The present invention relates to the identification of prognostic markers useful in determining the response of hepatitis c virus (HCV) infected patients to interferon alpha (IFN-α) treatment. The ...
US20110014185 METHODS INVOLVING GRAF POLYPEPTIDES  
The invention relates to a method of identifying a modulator of clathrin-independent endocytosis, said method comprising (i) providing a GRAF protein, said GRAF protein comprising a GAP domain;(ii)...
US20120184713 Compositions and Methods for Modulation of Bone Density and Biomineralization  
Compositions and methods for modulating FAM20C kinase action and identifying therapeutic agents for the same are disclosed.
US20110274703 DETECTION AND TREATMENT OF NON-DERMAL FIBROSIS  
The invention relates to methods for the diagnosis, prognosis, and treatment of non-dermal fibrosis, including lung (or pulmonary) fibrosis.
US20130065887 Treatment of Cancer with Dopamine Receptor Antagonists  
Described are methods of treating a cancer comprising administering to a subject in need thereof an effective amount of a dopamine receptor (DR) antagonist. The DR antagonist may be a phenothiazine...