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US20120220610 INHIBITIONS OF GLUTAMINASE C  
The present invention relates to a method of reducing the production of glutamate from glutamine by glutaminase C in a cell or tissue. The method involves inhibiting glutaminase C activity in the...
US20110172288 Compositions and Methods for the Identification, Assessment, Prevention and Therapy of Thymic Lymphoma or Hamartomatous Tumours  
The subject matter relates to newly discovered nucleic acid molecules and proteins associated with thymic lymphoma and hamartomatous tumors. Compositions and methods for detecting, characterizing,...
US20120309697 METHODS OF DIAGNOSING AND PROGNOSING COLONIC POLYPS  
Methods of diagnosing or prognosing a disease or condition associated with increased or over expression of macrophage inhibitory cytokine-1 (MIC-1) are disclosed. The methods typically involve...
US20130172253 METHOD OF DIAGNOSING AND TREATING OXIDATIVE STRESS-IMPAIRED WOUND HEALING  
The method of diagnosing and treating oxidative stress-impaired wound healing allows a practitioner to identify a subject at risk of having impaired wound healing by identifying the sensitivity of...
US20110082091 Method for Preclinical Testing of Immunomodulatory Drugs  
The invention teaches a method for testing a prospective or known immunomodulatory drug for T-cell activation, comprising the step of contacting in-vitro a peripheral blood mononuclear cell (PBMC)...
US20120178089 MATERIALS AND METHODS FOR THE IDENTIFICATION OF DRUG-RESISTANT CANCERS AND TREATMENT OF SAME  
Disclosed herein are diagnostic methods for identifying cancer and predicting drug resistance. The assays involve the detection of NEK2 gene expression alone or in combination with other genes or...
US20110183340 Phenotype-Genotype Relationship in Age-Related Macular Degeneration  
Age-Related Macular Degeneration (AMD) cases possessing the LOC387715 (rs 10490924) variant have a higher risk of neovascular AMD. Individuals with AMD who are homozygous for both variants might be...
US20110129861 MEASUREMENT OF ANTI-CCP AND SERUM AMYLOID A METHOD TO ASSESS RHEUMATOID ARTHRITIS  
The present invention relates to a method aiding in the assessment of rheumatoid arthritis. The method especially is used in assessing the absence or presence of rheumatoid arthritis in vitro. It...
US20130034867 METHODS FOR ISOTOPICALLY LABELING BIOMOLECULES USING MAMMALIAN CELL-FREE EXTRACTS  
Methods for producing an isotope-labeled mammalian, including a human, biomolecule, such as polypeptides and proteins, in a cell-free protein synthesis system. A biomolecule standard is produced...
US20120225433 Gene Expression Markers for Breast Cancer Prognosis  
The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
US20110312532 Gene Expression Markers for Breast Cancer Prognosis  
The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
US20140141449 Autoantibody Biomarkers for IGA Nephropathy  
Aspects of the present invention include methods for diagnosing and monitoring IgAN in a subject. In practicing one aspect of the subject methods, a sample from a subject is analyzed for the...
US20140030745 ASSAY KIT AND ANALYSIS METHOD  
An assay kit for reacting with an analyte includes a plurality of reaction vessels and a plurality of micro beads. Each of the reaction vessels contains a filter membrane with a plurality of pores,...
US20130172298 Okadaella Gastrococcus and Cancer  
The present invention provides compositions, methods of manufacture, process and uses for diagnosing, preventing, inhibiting, and treating the development and proliferation of diseases and...
US20110318264 METHODS AND COMPOSITIONS FOR DIAGNOSIS AND TREATMENT OF CANCER  
The present invention relates to the identification of nucleic acid and amino acid sequences that are characteristic of colorectal, in particular colonic, and gastric tumor tissues and colorectal,...
US20100035275 DIAGNOSIS AND RISK ASSESSMENT OF PANCREATIC DIABETES USING MR-PROADM  
The invention relates to a method for diagnosis and/or risk assessment of pancreatic diabetes, in particular of diabetic sequelae, wherein a determination of the marker mid-regional...
US20140057796 Method for the Diagnosis, Prognosis and Treatment of Breast Cancer Metastasis  
The present invention relates to a method for the diagnosis or the prognosis of metastasis in breast cancer which comprises determining if the c-MAF gene is amplified in a primary tumor sample....
US20120052516 METHOD FOR DIAGNOSING A HEMOGLOBIN-RELATED DISORDER  
The invention relates to a method for diagnosing, staging and/or monitoring a hemoglobin-related disorder such as β-thalassemia or a treatment against said hemoglobin-related disorder in a subject ...
US20130065782 Renal Cell Carcinoma Biomarkers and Uses Thereof  
The subject disclosure concerns methods for evaluation of renal cell carcinoma (RCC). Such methods include a method of determining of a diagnosis of the individual as having or not having RCC;...
US20140235479 SIGNATURES AND PCDETERMINANTS ASSOCIATED WITH PROSTATE CANCER AND METHODS OF USE THEREOF  
The present invention provides methods of detecting cancer using biomarkers.
US20110144198 BREAST CANCER PROGNOSTICS  
The present invention provides new methods, uses and means for breast cancer prognostics. The provided method for establishing a prognosis for a mammalian subject having a breast cancer, comprises...
US20130031646 MODEL SYSTEM OF ACANTHAMOEBA KERATITIS SYNDROME AND METHOD FOR SELECTING A TREATMENT THEREOF  
Methods for generating a feline model for ocular complications arising from amoeba infection are described. The invention further relates to screening methods for therapeutics for the treatment of...
US20110059857 MARKERS OF ACUTE KIDNEY FAILURE  
The present invention relates to the method of determining the risk of acute kidney injury comprising determining the amount of a marker selected from VCAN, NRP1, CCL2, CCL19, COL3A1, GZMM or any...
US20110135658 VHZ FOR DIAGNOSIS AND TREATMENT OF CANCERS  
We provide VHZ for use in a method of treatment, prophylaxis or alleviation of a cancer in an individual selected from the group consisting of: colon cancer, lung cancer, squamous cell carcinoma...
US20110201517 AUTOANTIGEN BIOMARKERS FOR EARLY DIAGNOSIS OF LUNG ADENOCARCINOMA  
Provided herein are novel panels of biomarkers for the detection and diagnosis of lung adenocarcinoma, and methods and kits for detecting these biomarkers in samples of individuals suspected of...
US20110256559 Method for Detecting Soluble Amyloid Precursor Protein (APP) Alpha and/or Soluble APP Beta  
The present invention relates to a method for detection or quantification of sAPPα and/or sAPPβ in a sample and their use for diagnosing and/or monitoring a neurodegenerative disease in a subject i...
US20140141986 CIRCULATING BIOMARKERS  
Biomarkers can be assessed for diagnostic, therapy-related or prognostic methods to identify phenotypes, such as a condition or disease, or the stage or progression of a disease. Circulating...
US20120283192 METHOD OF TREATING CONDITIONS ASSOCIATED WITH AIRWAY TISSUE REMODELING  
The invention provides a method for improving airway conductance in a subject in need thereof, the method comprising administering to the subject an effective amount of one or more of tumstatin; a...
US20140093530 MALARIA VACCINES  
The present invention relates to a synthetic antigenic sequence which represents a combination of epitope-containing sequences from the highly polymorphic block 2 repeat region of K1-type...
US20120128642 POTENCY MARKERS  
Methods for identifying trichogenic dermal cells, including dermal papilla cells and dermal sheath cells, capable of inducing hair follicle formation when injected into skin are provided....
US20130261059 Compositions and Methods for the Diagnosis and Treatment of Primary Insulin-Like Growth Factor Deficiency (PIGFD) and Idiopathic Short Stature (ISS)  
Compositions and methods for identifying patients at increased risk for PIGFD and ISS are disclosed.
US20130230855 Monocyte-derived Nucleic Acids and Related Compositions and Methods  
Nucleic acids encoding various monocyte-derived proteins and related compositions, including purified proteins and specific antibodies are described. Methods of using such composition are also...
US20110245104 Method for screening the sensitizing properties of chemical compounds  
A method is provided for screening the sensitizing properties of chemical compounds. The method is based on keratinocytes or cells that share important hallmarks of these cells, but other...
US20110152357 Micro-RNA-Based Compositions and Methods for the Diagnosis, Prognosis and Treatment of Multiple Myeloma  
Methods for assessing a pathological condition in a subject includes measuring an expression profile of one or more markers where a difference is indicative of multiple myeloma (MM) or a...
US20110318370 CXCL4L1 AS A BIOMARKER OF PANCREATIC CANCER  
The invention relates to the use of CXCL4L1 as a biomarker of pancreatic cancer in a patient. More particularly, the invention relates to a method for detecting a pancreatic cancer and/or...
US20130017192 Diagnosis and Treatment of Autoantibody-Mediated Heart Disease  
Provided herein are, inter alia, methods of diagnosing and treating autoimmune cardiomyopathy in subjects, based upon the detection of IgG4 autoantibodies to cardiac troponin I (cTnI).
US20120003228 METHODS FOR PREDICTING AUTOIMMUNE DISEASE RISK  
The invention relates to means and methods for determining whether a subject is at high or low risk of autoimmune disease progression by determining the CD8 or CD4 cell subtype of the subject....
US20110086360 METHOD FOR DETECTION OF IDIOPATHIC INTERSTITIAL PNEUMONIA  
The present invention provides a method for detecting idiopathic interstitial pneumonia, which comprises measuring the expression level of a periostin gene or the amount of a periostin protein in a...
US20140141980 Stratifying and annotating a clinical practice guideline  
Personalized medicine involves the use of a patient's molecular markers to guide treatment regimens for the patient. The scientific literature provides multiple examples of correlations between...
US20130171662 ASSAY  
This disclosure relates to a diagnostic/prognostic assay for prostate cancer and including kits used in said assay.
US20140080136 COMPOSITIONS, KITS, AND METHODS FOR DETECTING AND ANALYZING VESICLES  
Provided are compositions, kits, and methods for detecting a vesicle comprising a membrane permeable marker that is converted into a detectable marker inside the vesicle.
US20120322048 Materials and Methods for Assessing and Mapping Microbes and Microbial Biofilms on Wounds  
The subject invention provides point-of-care assays for assessing the topographical distribution of microbial biofilm and/or specific microorganisms in wounds.
US20100330586 METHOD FOR IDENTIFYING COMPOUNDS FOR TREATMENT OF PAIN  
Methods and products for the attenuation or treatment of pain and the reduction of nociception are described. The methods and products are based on the modulation of CNS intracellular chloride...
US20130116166 BIOMARKERS FOR IDIOPATHIC PULMONARY FIBROSIS  
Biomarkers, kits, and diagnostic and treatment methods for idiopathic pulmonary fibrosis are provided.
US20120244548 Methods Of Determining Skeletal Maturity  
The present invention provides methods to determine skeletal maturity.
US20130236919 METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING MOOD DISORDERS  
The present invention relates to methods of diagnosing, prognosing or treating diseases or disorders in which elevated or reduced levels of Aβ protein, including Aβ1-42 are prevalent. In p...
US20140066360 METHODS FOR USING SEMAPHORIN POLYPEPTIDES  
The present invention provides uses and methods of using a sema3E polypeptide and a sema3e polynucleotide encoding a sema3E polypeptide. The methods include decreasing airway remodeling in a...
US20120020954 METHODS OF PREDICTING CLINICAL COURSE AND TREATING MULTIPLE SCLEROSIS  
Provided are methods and kits for classifying a subject as being more likely to have benign multiple sclerosis (BMS) or as being more likely to have typical relapsing remitting multiple sclerosis...
US20130296408 MEDULLOBLASTOMA GENES AS TARGETS FOR DIAGNOSIS AND THERAPEUTICS  
Medulloblastoma (MB) is the most common malignant brain tumor of children. To identify the genetic alterations in this tumor type, we searched for copy number alterations using high density...
US20130202577 DIAGNOSTIC AND PROGNOSTIC ASSAY FOR BREAST CANCER  
The invention relates to the finding that T cell protein tyrosine phosphatase (TCPTP) has a tumour suppressor function. In one particular application, the invention provides a method of diagnosis...