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US20090288218 |
USE OF NAP GENE TO MANIPULATE LEAF SENESCENCE IN PLANTS
The present invention discloses transgenic plants having an altered level of NAP protein compared to that of a non-transgenic plant, where the transgenic plants display an altered leaf senescence...
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US20090288181 |
Transgenic animals for analyzing CYP3A4 cytochrome P450 gene regulation
The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional...
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US20090286849 |
MODULATION OF INSULIN LIKE GROWTH FACTOR I RECEPTOR EXPRESSION
The present invention provides compositions and methods for modulating the expression of growth factor gene. In particular, this invention relates to compounds, particularly oligonucleotide...
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US20090286714 |
Novel molecules of the card-related protein family and uses thereof
Novel CARD-9, CARD-10, or CARD-11 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated CARD-9, CARD-10, or CARD-11 proteins, the invention further provides...
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US20090286691 |
Oligonucleotide for Detection of Bacteria Associated with Sepsis and Microarrays and Method for Detection of the Bacteria Using the Oligonucleotide
The present invention relates to oligonucleotides for detection of sepsis-causing bacteria and a detection method using the oligonucleotides, more particularly to a microarry comprising at least...
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US20090286689 |
METHODS FOR ANALYZING DIFFERENTIAL GENE EXPRESSION ASSOCIATED WITH MYELOPROLIFERATIVE DISORDERS (MPD) CANCER DISEASE
The present application relates to gene analysis and, in particular, to gene expression profiling for identifying molecular signature of cancer disease, in particular the G1 phase of the cell...
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US20090286255 |
METHODS FOR ASSESSING EFFICACY OF CHEMOTHERAPEUTIC AGENTS
Methods are provided for accurately predicting efficacy of chemotherapeutic agents. Methods of the invention increase the positive predictive value of chemosensitivity assays by assessing both the...
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US20090286254 |
GENE SILENCING
Methods are disclosed for screening for the occurrence of gene silencing (e.g., post transcriptional gene silencing) in an organism. Also provided are methods for isolating silencing agents so...
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US20090286253 |
GENETIC LOCI ASSOCIATED WITH SCLEROTINIA TOLERANCE IN SOYBEAN
The invention relates to methods and compositions for identifying soybean plants that are tolerant, have improved tolerance or are susceptible to Sclerotinia sp. infection (the causative agent of...
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US20090286252 |
NRIF3, NOVEL CO-ACTIVATOR FOR NUCLEAR HORMONE RECEPTORS
Nucleic acids encoding NRIF3 are described. Polypeptides having amino acid sequences of NRIF3 proteins are also provided. A method is also provided for isolating and cloning NRIF3 cDNA. NRIF3 is...
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US20090286251 |
Enzyme Reagents for Amplification of Polynucleotides in the Presence of Inhibitors
Compositions and methods are provided for amplifying polynucletoides from samples containing inhibitors that normally inhibit amplification using an enzyme blend containing a plurality of...
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US20090286250 |
INCORPORATING SOLUBLE SECURITY MARKERS INTO CYANOACRYLATE SOLUTIONS
Methods for authenticating an article with a cyanoacrylate solution comprising a water soluble security marker compound are described. The methods for producing a nucleophilic security...
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US20090286249 |
INACTIVATABLE TARGET CAPTURE OLIGOMERS FOR USE IN THE SELECTIVE HYBRIDIZATION AND CAPTURE OF TARGET NUCLEIC ACID SEQUENCES
The present invention provides compositions, kits and methods for the selective hybridization and capture of a specific target nucleic acid. The specific target nucleic acid may be present in a...
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US20090286248 |
Methods for Determining Drug Responsiveness
The invention provides a diagnostics assay for measuring the responsiveness to a drug by comparing the mRNA levels of a gene that responds to the drug, such as a steroid, to the MRNA levels of a...
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US20090286247 |
Novel nucleic acid base pair
A novel artificial nucleic acid base pair which is obtained by forming a selective base pair by introducing a group having steric hindrance (preferably a group having steric hindrance and static...
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US20090286246 |
Methods for Identifying Compounds that Affect Expression of Cancer-Related Protein Isoforms
Provided herein are methods for screening compounds for their ability to modulate the expression of certain isoforms of proteins that are associated with cancer, such as isoforms of proteins that...
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US20090286245 |
TWO SLOW-STEP POLYMERASE ENZYME SYSTEMS AND METHODS
Compositions, kits, methods and systems for nucleotide sequencing comprising producing polymerase reactions that exhibit two kinetically observable steps within an observable phase of the...
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US20090286244 |
Fluorescent Color Markers
The invention provides a yeast-enhanced red fluorescent protein. In an embodiment of the invention, the yeast-enhanced red fluorescent protein is monomeric and is expressible in Candida albicans ....
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US20090286243 |
Compositions and methods for spinocerebellar ataxia
Mutations in the KCNC3 (Kv3.3) voltage-gated potassium channel gene result in spinocerebellar ataxia.
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US20090286242 |
MicroRNA Expression Profiling and Uses Thereof
Provided are methods and reagents for obtaining microRNA expression profiles in selected cell populations or sub-populations, such as stem cell or progenitor cell populations, and using such...
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US20090286241 |
SYSTEM AND METHOD FOR DETECTING A GENE MUTATION
A system for detecting a gene mutation encompasses a spectrum generation mechanism configured to acquire an amplified product containing the specific site sandwiched by recognition sites of a...
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US20090286240 |
BIOMARKERS OVEREXPRESSED IN PROSTATE CANCER
Biomarkers are identified by analyzing gene expression data using support vector machines (SVM) to rank genes according to their ability to separate prostate cancer from normal tissue. Proteins...
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US20090286239 |
Method of Detecting Individual Encapsulated Influenza Viruses, Primer Set for the Detection and Kit for the Detection
The present invention provides a method of rapidly, simply and accurately detecting capsular serotype Haemophilus influenzae other than Haemophilus influenzae Type b, a primer set for detecting...
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US20090286238 |
Methods to Monitor, Diagnose and Identify Biomarkers for Psychotic Disorders
A stimulated or non-stimulated T-cell sample can be used to diagnose or monitor a psychotic disorder, to identify a biomarker, or as to test a considerate as a potential therapeutic agent.
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US20090286237 |
Diagnostic Kits and Methods for Oesophageal Abnormalities
The invention relates to kits and methods for aiding the diagnosis of Barrett's oesophagus or Barrett's associated dysplasia. Preferred is a method comprising assaying cells from the surface of a...
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US20090286236 |
Method for detecting cell proliferative disorders
The present invention relates to the detection of a cell proliferative disorder associated with alterations of microsatellite DNA in a sample. The microsatellite DNA can be contained within any of...
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US20090286235 |
Mdr1 Snp in Acute Rejection
The present invention concerns a method for the prediction of acute renal transplant rejection by detecting a polymorphism in exon 26 of the MDR1 gene, optionally in combination with polymorphisms...
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US20090286234 |
IL10 SNP ASSOCIATED WITH ACUTE REJECTION
The present invention concerns a method for the prediction of acute renal transplant rejection by detecting a poly-morphism in the promoter region of the IL 10 gene, optionally in combination with...
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US20090286233 |
Method for Diagnosing Diabetic Retinopathy by Single Nucleotide Polymorphism, DNA Fragment Thereof, and Primer Thereof
Disclosed is a method for diagnosing diabetic retinopathy by a single nucleotide polymorphism of VEGF and its receptor.
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US20090286222 |
Mixed Cell Diagnostic Systems For Detection Of Respiratory, Herpes And Enteric Viruses
The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other...
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US20090285960 |
WHEAT HAVING NEW STARCH AND METHOD FOR PRODUCING IT
The object of the present invention is to provide a wheat which accumulates a starch with a novel property by controlling the expression of the enzymes described in claims. The present invention...
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US20090285883 |
Identification of gastrointestinal, pancreatic and cancer stem cell markers and methods of use thereof
DCAMKL-1 has been identified as a biomarker for stem cells, as well as cancer stem cells. Methods of detecting the presence of at least one stem cell, methods of isolating stem cells, and methods...
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US20090285836 |
USE OF SALINOSPORAMIDE A TO INHIBIT METASTASIS
The present invention relates to methods and compositions for treating and evaluating metastatic conditions.
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US20090285832 |
METHODS FOR TREATING SUNITINIB-RESISTANT CARCINOMA AND RELATED BIOMARKERS
A method of determining whether a tumor will be non-responsive to sunitinib therapy including detecting whether IL-8 or MMP12 expression levels in the tumor are elevated as compared to a control,...
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US20090285820 |
Methods of Treating Degenerative Disorders With Rac 1B Inhibitor
The invention relates to compositions and methods for treating degenerative disorders. More particularly, the invention relates to methods of treating amyloïd beta peptide-related disorders,...
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US20090285806 |
Methods and compositions for improving recombinant protein production
Nucleic acid molecules modified to enhance recombinant protein expression, e.g., that of Aβ peptide binding antibodies, and/or to reduce or eliminate mis-spliced and/or intron read-through (IRT)...
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US20090285801 |
Calcium-Sensing Receptor 2 (CaR2) and Methods for Using
The current disclosure provide a novel human calcium sensing receptor named CaR2 and the nucleotide sequence that encodes the receptor. The disclosure further provides antibodies specific for CaR2....
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US20090285800 |
Aberrant expression of CKS1 and CKS2 and uses thereof
The present invention is drawn to providing a therapeutic strategy for prostate cancer. In this regard, the present invention demonstrates that elevated expression of Cks1 contributes to...
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US20090285796 |
MUTANT JAK3 KINASE IN HUMAN LEUKEMIA
In accordance with the invention, a novel activating mutation (alanine 572 to valine) in JAK3 kinase has been discovered in human acute myelogenous leukemia (AML). The mutant JAK3 kinase was...
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US20090285788 |
RANDOM RNAi LIBRARIES, METHODS OF GENERATING SAME, AND SCREENING METHODS UTILIZING SAME
This invention provides expression vectors for a ribonucleic acid (RNA) molecule comprising a double-stranded region of random sequence, sets and libraries of same, methods of generating same, and...
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US20090285758 |
IN VIVO SYSTEM TO MONITOR TISSUE RESPONSES IN BIRDS
Methods of evaluating the tissue response to an agent in birds are provided. Also disclosed are methods of monitoring exposure to agents in birds and methods of determining the efficacy of vaccines.
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US20090282496 |
Androgen Receptor Related Methods for Treating Bladder Cancer
Disclosed are compositions and methods for treating bladder cancer.
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US20090281353 |
Use of dimethyl disulfide for methionine production in microoragnisms
The present invention features improved processes and organisms for the production of methionine. The invention demonstrates that a ΔmetF organism or a ΔmetE AmetH organism, for example, mutants...
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US20090281167 |
COMPOSITIONS AND METHODS RELATED TO MIRNA MODULATION OF NEOVASCULARIZATION OR ANGIOGENESIS
The present invention concerns methods and compositions for diagnosing and/or treating vascular diseases including cancer, cardiac diseases, vascular diseases of the eye, and inflammatory diseases....
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US20090281166 |
Treatment of Cancer by Inhibition of HSP27
A cancer is evaluated for selection of appropriate therapy by evaluating a sample of cancerous tissue to determine an expression of level of phosphatase and tensin homologue deleted from chromosome...
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US20090281090 |
BIOMARKERS FOR THE PREDICTION OF RESPONSIVENESS TO CLOZAPINE TREATMENT
This invention provides methods to predict the likelihood of suicidal or self-destructive behaviour in a patient during treatment. The method employs the detection of a VNTR polymorphism in the...
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US20090281061 |
Impaired Alleles of Genes Involved in Metabolic Pathways and Methods for Detecting and Using the Same
The invention is directed to enzyme variants, responsiveness thereof to cofactors, and in vivo assays for testing the activity of enzyme variants as well as the responsiveness thereof to cofactors.
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US20090281026 |
Use of BiP or a Variant, Homologue, Derivative or Fragment Thereof in the Manufacture of a Medicament for the Prevention or Treatment of Bone Loss or Bone Resorption
The present invention relates to the use of BiP or a variant, homologue, derivative or fragment thereof in the manufacture of a medicament for the prevention or treatment of bone loss or bone...
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US20090280996 |
DELTA 17 DESATURASE AND ITS USE IN MAKING POLYUNSATURATED FATTY ACIDS
The present invention relates to Δ17 desaturases, which have the ability to convert ω-6 fatty acids into their ω-3 counterparts (i.e., conversion of arachidonic acid [20:4, ARA] to...
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US20090280995 |
METHOD OF DIAGNOSIS
Provided are methods, kits and arrays for use in determining whether a scar of interest is keloid or non-keloid in nature. These determine keloid or non-keloid nature based on comparison of gene...
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