|
Match
|
Document |
Document Title |
|
|
US20100323361 |
METHODS, SYSTEMS AND KITS FOR DETECTING PROTEIN-NUCLEIC ACID INTERACTIONS
Methods, systems and kits for detecting protein-nucleic acid interactions, in particular, detecting the genomic location to near-base pair resolution at which a particular protein (e.g.,... |
|
|
US20120028264 |
METHOD FOR USING GENE EXPRESSION TO DETERMINE PROGNOSIS OF PROSTATE CANCER
Molecular assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis... |
|
|
US20120135402 |
GENE SEQUENCE VARIANCES IN GENES RELATED TO FOLATE METABOLISM HAVING UTILITY IN DETERMINING THE TREATMENT OF DISEASE
The present disclosure describes the use of genetic variance information for folate transport or metabolism genes or pyrimidine transport or metabolism genes in the selection of effective methods... |
|
|
US20130210024 |
COMBINATION TREATMENT OF CANCER
The present technology relates to a method of treating cancer by sensitizing human tumours to DNA damaging therapies through activating FBXO32 expression. Transactivation of FBXO32 through the... |
|
|
US20120214677 |
LUCIFERASE BIOSENSOR
A modified beetle luciferase protein which is an environmentally sensitive reporter protein is provided. |
|
|
US20110287963 |
SYSTEM USEFUL FOR REPORTING PROTEIN-PROTEIN INTERACTIONS IN THE BACTERIAL PERIPLASM
One aspect of the present invention relates to a reporter system for detection of protein-protein interactions in the periplasm of a prokaryotic host cell. The reporter system includes a first... |
|
|
US20110250609 |
Methods For The Detection, Analysis And Isolation Of Nascent Proteins
This invention relates to non-radioactive markers that facilitate the detection and analysis of nascent proteins translated within cellular or cell-free translation systems. Nascent proteins... |
|
|
US20120171693 |
Methods for Generating Novel Stabilized Proteins
The disclosure provides methods for identifying and producing stabilized chimeric proteins. |
|
|
US20120040367 |
CONSTRUCT SYSTEM AND USES THEREFOR
The present invention discloses construct systems and methods for comparing different iso-accepting codons according to their preference for translating RNA transcripts into proteins in cell or... |
|
|
US20120171694 |
PREDICTIVE MARKERS AND BIOMARKER PANELS FOR OVARIAN CANCER
Methods are provided for predicting the presence, subtype and stage of ovarian cancer, as well as for assessing the therapeutic efficacy of a cancer treatment and determining whether a subject... |
|
|
US20110281750 |
Identifying High Risk Clinically Isolated Syndrome Patients
Disclosed herein are methods and kits for identifying clinically isolated syndrome (CIS) patients at high risk of developing multiple sclerosis (MS). |
|
|
US20110287957 |
METHODS AND KITS FOR DIAGNOSING COLORECTAL CANCER
The invention pertains to a method for early detection and screening of colorectal cancer in human subjects based on RNA isolated from blood obtained from said subject. According to the invention,... |
|
|
US20100323358 |
Use of KIR genes for predicting response to therapy
The present invention relates to the use of at least one Killer cell immunoglobulin-like receptor gene for the identification of subjects likely to respond to tumour necrosis factor-based therapy.... |
|
|
US20110183858 |
GRADING OF BREAST CANCER
Methods and compositions for the identification of breast cancer grade signatures are provided. The signature profiles are identified based upon multiple sampling of reference breast tissue... |
|
|
US20150211073 |
MRNA-BASED GENE EXPRESSION FOR PERSONALIZING PATIENT CANCER THERAPY WITH AN MDM2 ANTAGONIST
Use of at least an MDM2 gene panel, preferably a four gene MDM2 gene panel, as a biomarker for predicting the response to a MDM2 antagonist. |
|
|
US20110230372 |
GENE EXPRESSION CLASSIFIERS FOR RELAPSE FREE SURVIVAL AND MINIMAL RESIDUAL DISEASE IMPROVE RISK CLASSIFICATION AND OUTCOME PREDICTION IN PEDIATRIC B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA
The present invention relates to the identification of genetic markers patients with leukemia, especially including acute lymphoblastic leukemia (ALL) at high risk for relapse, especially high... |
|
|
US20150218636 |
Mutations In Calmodulin Genes
The present invention relates to an isolated polynucleotide encoding at least a part of calmodulin and an isolated polypeptide comprising at least a part of a calmodulin protein, wherein the... |
|
|
US20120148559 |
COMPOSITIONS AND METHOD FOR DEIMMUNIZATION OF PROTEINS
The invention provides deimmunized mutant proteins having reduced immunogenicity while exhibiting substantially the same or greater biological activity as the proteins of interst from which they... |
|
|
US20120040848 |
MOLECULAR SIGNATURE OF LIVER TUMOR GRADE AND USE TO EVALUATE PROGNOSIS AND THERAPEUTIC REGIMEN
The present invention concerns a method to determine the gene expression profile on a sample previously obtained from a patient diagnosed for a liver tumor, comprising assaying the expression of a... |
|
|
US20110183862 |
MOLECULAR SIGNATURE OF LIVER TUMOR GRADE AND USE TO EVALUATE PROGNOSIS AND THERAPEUTIC REGIMEN
The present invention concerns a method to determine the gene expression profile on a sample previously obtained from a patient diagnosed for a liver tumor, comprising assaying the expression of a... |
|
|
US20100297639 |
QUANTITATIVE/SEMI-QUANTITATIVE MEASUREMENT OF EPOR ON CANCER CELLS
The present invention provides for assays useful in predicting whether a cancer patient risks suffering erythropoietin-induced tumor progression if treated with erythropoietin. More specifically,... |
|
|
US20110104693 |
QUANTITATIVE NUCLEASE PROTECTION SEQUENCING (qNPS)
The present invention provides a new approach, quantitative Nuclease Protection Sequencing (qNPS™), for addressing several challenges that face sequencing and which provides improvements for... |
|
|
US20110091502 |
HUMAN PARVOVIRUS: HUMINK PARVOVIRUS
Provided herein are sequences of the genomes and encoded proteins of a new human parvovirus, Humink parvovirus, and variants thereof. Also provided are methods of detecting the Humink parvovirus... |
|
|
US20100310574 |
METHODS AND COMPOSITIONS FOR THE TREATMENT AND DIAGNOSIS OF STATIN-INDUCED MYOPATHY
The invention provides compositions and kits containing an atrogin-1 inhibitor compound useful for the treatment of a statin-mediated myopathy. Kits for the diagnosis of a statin-mediated myopathy... |
|
|
US20110150774 |
SCREENING FOR MODULATORS OF CES1 AND/OR CES3 FOR THE TREATMENT OF ACNE, OF SEBORRHOEIC DERMATITIS OR OF HYPERSEBORRHOEA
An in vitro or in vivo method for screening for candidate compounds for the preventive or curative treatment of acne, of seborrhoeic dermatitis or of skin disorders associated with... |
|
|
US20120225425 |
Cathepsin E as a Marker of Colon Cancer
Elevated levels of cathepsin E (catE) are demonstrated to be diagnostic of intestinal forms of cancer, such as colorectal cancer. Elevated levels of cathepsin E (catE, monomeric forms) are... |
|
|
US20110044960 |
MEDICAMENT, DENTAL MATERIAL, AND METHOD OF SCREENING
The present invention provides a novel and creative dental materials for treatment of pulpitis and/or enhancement of dentinogenesis. The dental materials of the present invention contain at least... |
|
|
US20120122113 |
Signature Of Secreted Protein Isoforms Specific To Ovarian Cancer
The present invention relates to the identification of secreted protein isoforms specific in ovarian cancer and methods for diagnosis or prognosis of ovarian cancer in a subject by detecting the... |
|
|
US20140234287 |
SUMOYLATION OF SERCA2a AND CARDIOVASCULAR DISEASE
Methods for treating cardiovascular disease, and in particular heart failure, are provided comprising administering a therapeutically effective amount of a modulator of SERCA2a post-translation... |
|
|
US20110262920 |
METHODS FOR PREDICTING SURVIVAL IN CANCER PATIENTS
A method for survival prediction in cancer patients is provided. In one embodiment, the survival prediction is determined by the presence or absence of KRAS gene region deletion and/or loss of... |
|
|
US20130305413 |
Pericarp tissue preferred regulatory region and method of using same
A Zea mays regulatory region is shown, which provides improved seed preferred, and particularly pericarp preferred expression in plants. Methods of use are also shown in preferentially expressing... |
|
|
US20150148248 |
MMP2 AS A PREDICTIVE BIOMARKER OF RESPONSE TO ANTIANGIOGENIC THERAPY AND SURVIVAL AFTER THERAPY IN CANCER PATIENTS
The present invention relates to the use of matrix metalloproteinase-2 (MMP2) as a predictive biomarker of response to antiangiogenic therapy and survival after antiangiogenic therapy in cancer... |
|
|
US20150093373 |
TREATMENT OF PULMONARY VASCULAR REMODELING WITH NEPRILYSIN
The present invention relates to agonists of Neprilysin and their use in preventing and treating pulmonary vascular remodeling. Also described are diagnostic and screening applications stemming... |
|
|
US20120121573 |
Treatment of Pulmonary Vascular Remodeling With Neprilysin
The present invention relates to agonists of Neprilysin and their use in preventing and treating pulmonary vascular remodeling. Also described are diagnostic and screening applications stemming... |
|
|
US20140249150 |
ACTIVATORS OF PYRUVATE KINASE M2 AND METHODS OF TREATING DISEASE
The invention described herein features methods, compositions, and kits that utilize activators of pyruvate kinase M2 (PKM2) for the treatment or amelioration of disorders related to PKM2 function... |
|
|
US20110212847 |
COMPOSITIONS AND METHODS RELATING TO MONITORING ALCOHOL CONSUMPTION AND ALCOHOL ABUSE
Methods and compositions according to embodiments of the present invention are provided that specifically and sensitively detect alcohol consumption and whether alcohol consumption is moderate or... |
|
|
US20110072539 |
Compositions and Methods for Modulating Pigment Production in Plants
This invention relates to polynucleotides encoding novel transcription factors and to the encoded transcription factors, that are capable of regulating anthocyanin production in plants. The... |
|
|
US20110189669 |
METHODS OF AIDING IN THE DIAGNOSIS OF PROSTATE CANCER
The current invention provides a method for aiding in the assessment of prostate cancer (including metastatic prostate cancer) and/or benign prostate hyperplasia in a patient, wherein the method... |
|
|
US20110097715 |
METHOD FOR PURIFYING OR DETECTING A TARGET PROTEIN
A method for purifying or detecting a target protein present in a solution, includes, before carrying out the actual detection or purification step, a step of contacting the solution with an... |
|
|
US20100322949 |
METHODS FOR DIAGNOSING AND TREATING ASTROCYTOMAS
The invention relates to the identification of astrocytoma markers, astrocytoma stem cells and markers of such stem cells, and diagnostic, prognostic and therapeutic methods based on an... |
|
|
US20100330575 |
MOLECULAR DIAGNOSTICS REAGENTS AND METHODS
The present invention relates to automated devices and methods for the extraction of nucleic acids from cells, the amplification of segments of nucleic acid and the detection of nucleic acids, all... |
|
|
US20110183337 |
Method and Kit for Use in the Differentiation of IBD and IBS and Further Distinction Between Disease Types of IBD
A quantification of the expression levels of a number of specific genes and their corresponding proteins can be utilized in accurately determining, using samples from faeces or blood, whether the... |
|
|
US20100129797 |
USE OF GENETIC MODIFICATIONS IN HUMAN GENE CHK1 WHICH CODES FOR CHECKPOINT KINASE 1
The invention relates to an in vitro method for predicting disease risks, progression of diseases, drug risks, success of treatment and for finding drug targets by looking for one or more genetic... |
|
|
US20110067147 |
Development of Very Early Flowering and Normal Fruiting Plum With Fertile Seeds
To produce early flowering genotypes, plum (Prunus domestica) was transformed with the poplar (Populus trichocarpa) Flowering Locus T1 (PtFT1) gene. Ectopic expression of 35S::PtFT1 Induced early... |
|
|
US20110059449 |
METHODS AND COMPOSITIONS FOR DIAGNOSING AND MONITORING TRANSPLANT REJECTION
Methods of diagnosing or monitoring transplant rejection or cytomegalovirus infection in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the... |
|
|
US20120171688 |
Gene Expression Markers for Colorectal Cancer Prognosis
A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their... |
|
|
US20110251086 |
NEUROBLASTOMA PROGNOSTIC MULTIGENE EXPRESSION SIGNATURE
The current invention relates to new tools and methods enabling neuroblastoma patient stratification into prognostic favorable or unfavorable groups. The invention is based on the re-analysis of... |
|
|
US20050164208 |
Storage of genetic information
Methods for the long-term storage of hereditary information such as DNA are described herein. In some instances, lyophilized DNA and sugar is introduced into a hermetically sealed vial. Kits for... |
|
|
US20120077203 |
REPORTER GENE CONSTRUCT, ASSAY KIT AND DETECTION METHOD
According to one embodiment, there is provided a reporter gene construct. The reporter gene construct comprises a transcriptional regulatory sequence and a reporter gene that is functionally bound... |
|
|
US20120213761 |
USE OF GSTP1
The invention discloses the use of glutathione S-transferase P1 (GSTP1) for the prevention or treatment of cardiomyopathies or ischemic heart diseases and for the diagnosis thereof. |