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US20090028866 |
USE OF CCR9, CCL25/TECK, AND NITEGRIN alpha4 IN DIAGNOSIS AND TREATMENT OF MELANOMA METASTASIS IN THE SMALL INTESTINE
The invention relates to methods for determining whether a melanoma will metastasize or has metastasized to the small intestine in a subject by detecting or quantifying the expression of the CCR9,... |
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US20060240463 |
Markers associated with the therapeutic efficacy of glatiramer acetate
The present invention is directed to methods and kits based, at least in part, on the identification of allele-specific responsiveness or non-responsiveness to glatiramer acetate for the treatment... |
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US20070271634 |
Preventing stress-induced apoptosis in plants
The invention relates to methods of identifying nucleic acids that modulate apoptosis in plants, particularly apoptosis induced by an abiotic or biotic stress, as well as to transgenic plants and... |
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US20090186345 |
Instrument and method for nucleic acid isolation
According to the present invention, purified nucleic acids are isolated without the complete removal of components of a washing reagent. Also, nucleic acids are isolated in an elution reagent by... |
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US20100112587 |
TRANSCRIPTOMIC BIOMARKERS FOR INDIVIDUAL RISK ASSESSMENT IN NEW ONSET HEART FAILURE
A novel transcriptomic biomarker for prognosis in heart failure has a direct clinical application in prediction of prognosis in new onset heart failure, heart disease, heart disorders and... |
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US20100129491 |
Tryptophan transporter gene and use thereof
The present invention relates to a tryptophan transporter gene and to uses of the gene. The invention relates in particular to a brewer's yeast which can control the tryptophan assimilation... |
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US20070219155 |
TREATING TRINUCLEOTIDE REPEAT CONDITIONS
This document provides methods and materials related to treating trinucleotide repeat conditions. For example, methods and materials for treating a trinucleotide repeat condition as well as... |
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US20100190650 |
TRANSCRIPTOMIC BIOMARKER OF MYOCARDITIS
Molecular signatures that function as very sensitive diagnostic biomarker for myocarditis, heart disease and disorders thereof, are identified. |
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US20080299077 |
ISOLATION AND GROWTH OF STEM CELLS FROM HEMANGIOMAS
The present invention describes stem cells and progenitor cells derived from hemangiomas, including testing of angiogenic inhibitors using these cells. The invention as described is useful in... |
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US20050208539 |
Quantitative amplification and detection of small numbers of target polynucleotides
Devices, assemblies, systems and methods described herein enable detection of as few as a single copy of a target nucleic acid molecule. Polynucleotides copied from a single or a small number of... |
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US20080045485 |
Methods of diagnosing synovial disease in a mammal by detecting bacterial DNA in synovial tissues from dogs with inflammatory knee arthritis and degenerative anterior cruciate ligament rupture
Method of diagnosing persistent, chronic synovitis and progressive joint degradation in the joint of a mammal. The method including providing a test sample comprising synovial fluid, cell or... |
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US20080124723 |
COMBINED THERMAL DEVICES FOR THERMAL CYCLING
The invention relates to systems and methods including a combination of thermal generating device technologies to achieve more efficiency and accuracy in PCR temperature cycling of nucleic samples... |
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US20080293830 |
Method For Activating Efferent Sympathetic Nerves Innervating Adipose Tissues To Improve Obesity And Symptoms Associated Therewith
A method for activating an efferent sympathetic nerve innervating an adipose tissue and improving obesity-associated symptoms is provided, comprising stimulating an afferent vagal nerve from the... |
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US20070099857 |
Methods and means for inhibiting fever
Microsomal prostaglandin E synthase-1 (m PGES-1) catalyses the terminal step in the synthesis of prostaglandin E2 (PGE2) in the brain. In the absence of mPGES-1, animals do not develop... |
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US20100305038 |
DIAGNOSTIC OF IMMUNE GRAFT TOLERANCE USING TMTC3 GENE EXPRESSION LEVELS
The present invention concerns a method for the in vitro diagnosis or prognosis of a graft tolerant or graft non-tolerant phenotype, comprising: determining from a grafted subject biological... |
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US20070009931 |
Negative correlation between IRP-2 and Transferrin receptor expression as a diagnostic of Alzheimer's disease
A method of diagnosing Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) is disclosed which was identified by the fact that an increased level of iron regulating protein-2 (IRP-2) was... |
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US20060292693 |
Monoclonal antibody with the capability of neutralizing enterovirus type 71 infection
The present invention provides a monoclonal antibody capable of neutralizing EV71 infection. |
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US20090311700 |
Methods for Breast Cancer Prognosis
The present invention relates to methods, kits and systems for the prognosis of the disease outcome of breast cancer in untreated breast cancer patients. More specific, the present invention... |
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US20100003257 |
Diagnosis of nasopharyngeal carcinoma and suppression of nasopharyngeal carcinoma invasion
A diagnostic method for NPC based on the activation level of the Gα12 signaling pathway in a subject. Also disclosed is a method of inhibiting NPC invasion by suppressing the Gα12 signaling... |
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US20090028860 |
Use of IL-17 Expression to Predict Skin Inflammation; Methods of Treatment
Provided are methods for diagnosing the propensity of a subject to develop skin inflammation, in particular, psoriasis. Also provided are methods of treatment with antagonists of IL-17 and/or IL-23. |
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US20060025363 |
Use of antisense oligonucleotides for the treatment of degenerative skin conditions
A pharmaceutical or cosmetic composition for topical application containing one or more oligonucleotides which are capable of hybridizing with a mRNA or a gene sequence which codes for a... |
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US20080124730 |
Modified siRNA Constructs for Detecting RISCs
The present teachings provide novel methods, compositions, and kits for detecting siRNA-containing RISCs. In some embodiments, modified siRNA constructs are employed that contain an anti-sense... |
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US20050255506 |
NOS-2 and glaucoma
Methods of diagnosis of the presence or absence of an NOS-2-associated increased risk of glaucoma, or of a NOS-2-associated decreased risk of glaucoma, are described, in which a sample is tested... |
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US20090275018 |
Detection of hepatotoxic cyanobacteria
The present invention relates to methods and kits for the detection of toxic cyanobacteria, in particular of hepatotoxin-producing cyanobacteria. |
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US20050014173 |
Parkinson's disease markers
Nucleic acids and polypeptides are provided that are associated with PD. Methods and articles of manufacture for screening individuals for susceptibility to PD, including susceptibility to a... |
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US20070277251 |
Diagnosis and Prediction of Parkinson's Disease
The present invention provides an in vitro method for diagnosis or prediction of Parkinson's disease in a subject, the method comprising testing for a mutation of a mitochondrial DNA polymerase... |
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US20110027779 |
POLYNUCLEOTIDE PRIMERS
A polynucleotide comprising at least the final six nucleotides of one of the following primer sequences, or a sequence complementary thereto: SEQ. ID NOS. 3 to 16, 18, 20 to 33, 35 or 37 to 39. A... |
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US20070003575 |
Viral and viral associated MiRNAs and uses thereof
Described herein are novel polynucleotides associated with viral infections. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis,... |
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US20090005337 |
Pde11a Mutations in Adrenal Disease
The invention provides previously uncharacterized variants of PDE11A that are correlated with a newly discovered form of Cushing Syndrome that presents at a young age. The invention also provides... |
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US20060134624 |
Polymerase-based protocols for the introductions of deletions and insertions
The invention relates to primers, libraries of primer, kits and methods for site-specific in vitro mutagenesis comprising: (a) cloning a parental polynucleotide into a vector comprising a cloning... |
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US20080193507 |
Wound Healing Profile
The present invention relates to compositions and methods for tissue regeneration, particularly for treating skin lesions such as wounds. In one aspect, the invention provides wound healing... |
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US20080044403 |
Immune Markers Used for Diagnosis and Therapy in Connection With Transplant Reactions
The invention relates to immune markers for detecting inflammations, immune reactions, and particularly transplant tolerance or transplant reactions, a method for detecting transplant reactions or... |
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US20070072181 |
Combination therapy for treating alphavirus infection and liver fibrosis
The present invention provides methods for treating alphavirus infections; methods of treating hepatitis C virus (HCV) infections; methods of treating West Nile virus infection; methods of... |
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US20090215765 |
Neuroprotective compounds for treating optic neuropathies
Neuroprotective compounds for treating optic neuropathies and screening methods for identifying neuroprotective compounds. |
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US20080248000 |
Stem Cells, Method For Their Purification, Identification, and Use
Herein is described a new population of circulating CD14+cells, with a low density surface expression of CD34 and endowed with stem capacity, a method for their purification and identification,... |
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US20070031886 |
Detecting recessive diseases in inbred populations
Techniques of using statistical analysis of genetic data to determine likely markers for a recessive genetic disease or trait. One embodiment of these techniques includes the steps of obtaining... |
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US20060178325 |
Modulation of growth hormone receptor expression and insulin-like growth factor expression
Compounds, compositions and methods are provided for modulating the expression of growth hormone receptor and/or insulin like growth factor-I (IGF-I). The compositions comprise oligonucleotides,... |
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US20090209580 |
ANTITUMOR AGENT FOR THYROID CANCER
The objective of the present invention is to provide a pharmaceutical composition and a therapeutic method that are specifically effective against at least one disease selected from multiple... |
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US20070212715 |
BACTERIA DETECTION DEVICE, BACTERIA DETECTION METHOD AND BACTERIA DETECTION KIT
The present invention provides a bacteria detection device, bacteria detection method and bacteria detection kit enabling rapid and accurate determination of bacteria present in a test sample, and... |
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US20110027788 |
REAGENT AND KIT FOR CLASSIFYING AND COUNTING LEUKOCYTES, THE PREPARATION THEREOF, AND PROCESS FOR CLASSIFYING AND COUNTING LEUKOCYTES
A reagent for classifying and counting leukocytes containing (1) a cyanine fluorescent dye; and (2) a glycoside compound; a reagent kit containing the reagent for classifying and counting... |
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US20100291563 |
ASSESSING TISSUE REJECTION
This document relates to methods and materials involved in assessing tissue rejection (e.g., organ rejection) in mammals. For example, methods and materials involved in detecting tissue rejection... |
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US20090233942 |
Genetic markers associated with response to antidepressants
Markers of the ACE, ATP5C3, BCL2L1, CYP2C9, DRD3, FOS, DTNBP1, GABRG3, GRIA4, LAMA4, MAPK1, NPY1R, OPRD1, OPRM1, PER3, PLCB1, PSMD1, ABI1, LOC402382, and NCALD genes, and their association with... |
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US20070117095 |
Diagnostic method for neonatal or infantile epilepsy syndromes
A method for the diagnosis of a neonatal or infantile epilepsy syndrome as BFNIS in a patient comprising testing for the presence of an alteration in the SCN2A gene, including in a regulatory... |
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US20100092954 |
Method for Determining the Genetic Basis for Physiological Changes in Organisms
The present invention provides a method for discovering the basis of changes in the observable properties of organisms by subjecting an organism to selection. Individual organisms with observable... |
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US20090220973 |
OBESITY AND BODY FAT DISTRIBUTION
Described are methods for predicting and diagnosing genetically-based obesity and body fat distribution, and for identifying compounds for the treatment and prevention of obesity. |
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US20090162855 |
Identification of Genetic Variants Associated with Increased Severity of Pulmonary Disease
A method of determining a genetic component contributing to the severity of a pulmonary disease in a patient comprises determining the presence or absence of one or more single nucleotide... |
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US20100112568 |
METHODS AND KITS FOR DIAGNOSIS OF MULTIPLE SCLEROSIS IN PROBABLE MULTIPLE SCLEROSIS SUBJECTS
Provided are methods and kits for determining the probability of a subject diagnosed with probable multiple sclerosis to develop definite diagnosis of multiple sclerosis by determining the... |
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US20070026402 |
Genetic marker of response to atypical antipsychotics and antidepressants methods for use thereof
The invention provides methods of identifying candidate psychiatric patients, or patients with movement disorder, for treatment with receptor site or increases density of D2 dopamine receptors.... |
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US20090209551 |
ESSENTIAL TREMOR DIAGNOSTIC AND TREATMENT
The invention relates to an in vitro method for diagnosing essential tremor wherein a mutation of dopamine D3 receptor gene or protein is sought. The invention further relates to the use of a... |
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US20100291029 |
METHODS OF USING IL-21
An allelic variation in the IL-21 receptor can result in reduced IFN-γ production in individuals and can require administration of different doses of IL-21 to achieve therapeutic effects seen... |