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US20080153084 |
Obesity Markers And Uses Thereof
The present invention relates to a method for identification of a nucleotide substitution in the gene encoding for the neuromedin- or quantifying its levels of mRNA, to allow the determination of... |
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US20070196849 |
Double-ligation Method for Haplotype and Large-scale Polymorphism Detection
The present teachings provide methods, compositions, and kits for querying the identity of a target polynucleotide strand comprising. In some embodiments, the present teachings provide a method... |
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US20110020826 |
METHODS FOR ASSESSING EFFICACY OF CHEMOTHERAPEUTIC AGENTS
Methods are provided for accurately predicting efficacy of chemotherapeutic agents. Methods of the invention increase the positive predictive value of chemosensitivity assays by assessing both the... |
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US20100047803 |
BIOMARKERS FOR ACETAMINOPHEN TOXICITY
Materials and methods for evaluating cellular responses to acetaminophen and assessing susceptibility to liver damage. |
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US20060177824 |
Salmonella detection identification
A nucleic acid specific for use in detecting and differentiating Salmonella from other bacteria comprises at least 10 contiguous nucleotides and is capable of selectively hybridizing to at least a... |
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US20110071047 |
PROMOTER DETECTION AND ANALYSIS
An array-based method for promoter detection and analysis is provided. Promoter sequence candidates are analyzed simultaneously in one reaction vial utilizing a plurality of vectors, each... |
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US20110067123 |
MAO-B ELEVATION AS AN EARLY PARKINSON'S DISEASE BIOMARKER
This invention pertains to development of a new animal model for Parkinson's Disease (PD) and to the discovery that elevated monoamine oxygenase B (MOA-B) expression and/or activity is a strong... |
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US20100209917 |
POLYMORPHIC LENGTH OF FOXE1 ALANINE STRETCH AND GENETIC SUSCEPTIBILITY TO THYROID DYSGENESIS
The present invention concerns a method for diagnosis an increased likelihood of developing a thyroid dysgenesis (TD) for an individual, wherein said method comprises determining the length of the... |
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US20110004411 |
METHOD FOR ADJUSTING RESULTS OF A POLYMERASE CHAIN REACTION (PCR) INSTRUMENT
Methods of managing results of a real-time polymerase chain reaction (PCR) instrument and software associated with such methods are described herein. One disclosed method, among others, comprises... |
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US20080131881 |
Markers For Brain Damage
Methods to identify markers for brain damage using fresh brain tissue and methods and compositions for detecting these markers are disclosed. |
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US20100304390 |
METHODS FOR DETECTING GENE DYSREGULATIONS
Described herein are methods, compositions and kits directed to the detection of gene dysregulations such as those arising from gene fusions and/or chromosomal abnormalities, e.g. translocations,... |
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US20080064028 |
Quantitative Pcr Method of Detecting Specific Plant Genus in Food or Food Ingredient
Provided is a method of quantifying a specific plant genus in a food or a food ingredient by a PCR method, comprising: (i) preparing a sample for correction where a sample derived from the... |
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US20060063162 |
Biological marker for inflammation
The present disclosure provides methods and compositions for the diagnosis and treatment of inflammation, in particular, vascular pathologies. One aspect provides an array capable of detecting the... |
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US20070059745 |
Blood assessment of injury
Methods of injury assessment in an individual include the steps of determining a pattern of expression exhibited by blood cells obtained from an individual and comparing the pattern of expression... |
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US20100285047 |
THERAPEUTICS AND DIAGNOSTICS FOR GROUP A STREPTOCOCCI
Immunogenic compositions and vaccines are described comprising GAS Markers. Methods for detecting GAS diseases in a subject are also described comprising measuring GAS markers in a sample from the... |
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US20070009927 |
Methods and compositions for prenatal diagnosis of mental retardation
Methods and compositions for the diagnosis of mental retardation are provided. |
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US20090028831 |
STEM CELL REGULATOR, COMPOSITIONS AND METHODS OF USE
The disclosure provides methods and compositions comprising Slit2 agonists and antagonists useful for modulating hematopoietic stem cell (HSC) proliferation and growth. In some aspects, the... |
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US20100071078 |
RSPONDINS AS MODULATORS OF ANGIOGENESIS AND VASCULOGENESIS
The present invention relates to the use of Rspondins, particularly Rspondin2 (Rspo2) or Rspondin3 (Rspo3) or Rspondin nucleic acids, or regulators or effectors or modulators of Rspondin, e.g.... |
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US20050032102 |
Mapping genomic rearrangements
Methods and kits for monitoring genomic changes in an organism are provided. The complexity of a genomic sample is reduced in a reproducible manner and hybridized to an array of probes that are... |
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US20100227908 |
DIAGNOSTIC, PROGNOSTIC AND TREATMENT METHODS
The present invention relates generally to diagnostic and prognostic protocols for schizophrenia and its manifestations including sub-threshold phenotypes and states thereof. Profiling and... |
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US20050170400 |
Method for identifying bead location information
Location information of carriers such as beads arranged inside a capillary represented by a probe array is detected accurately, and an identification method for various materials is developed... |
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US20110033844 |
USE OF LYSOSOMAL CARBOXYPEPTIDASE C (PRCP) AS A THERAPEUTIC OR DIAGNOSTIC TARGET
The invention provides a human PRCP which is associated with the cardiovascular diseases, hematological diseases, neurological diseases and cancer. The invention also provides assays for the... |
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US20080317741 |
Biomarkers For Anti-Nogo-A Antibody Treatment in Spinal Cord Injury
This disclosure of this invention confirms, at the level of gene expression, the injured spinal cord and motor cortex as the primary sites of action of the anti-Nogo-A antibody treatment applied... |
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US20090178152 |
Use of the Ornithine Transcarbamylase (OTC), as a Marker for Diagnosing Brain Damages
The present invention pertains to the domain of brain diseases, and provides novel markers and methods for diagnosing a brain alteration in an individual, especially in patients suffering from... |
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US20090163764 |
METHODS OF DETERMINING HUMAN EGG COMPETENCY
The inventors have discovered inter alia, that when the chromosome complement of a first polar body (PB-I) is normal, it alone is in more than 80% of cases sufficient to predict that an embryo... |
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US20100223678 |
protein isoforms of the pif-family and uses thereof
A method for screening for or diagnosis or prognosis of a neurological disorder associated with de-regulated glutamate signalling in a subject, for determining the stage or severity of such a... |
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US20080199855 |
Identification And Characterization Of A Subset of Glioblastomas Sensitive To Treatment With Imatinib
The present invention relates to methods for in vitro diagnosing a cell proliferative disease in a mammal, for predicting the behaviour of a mammal having a cell proliferative disease in response... |
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US20110065104 |
REAL-TIME ASSAYS OF NEURO-HUMORAL FACTORS TO ASSESS CARDIOVASCULAR STRESS
The present invention relates to rapid assays for neuro-humoral factors modulated in response to cardiovascular stress and integration of data obtained from such assays to provide profiles of... |
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US20070218493 |
Diagnostic marker for interferon responsiveness in multiple sclerosis
Disclosed is a method of determining interferon responsiveness in a patient suffering from multiple sclerosis. The method comprises determining an amount of a XAF-1 gene expression level in a... |
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US20100047775 |
Method of identifying individuals at risk of perioperative myocardial injury, major adverse cardiac events, cognitive decline, arrhythmias, depression or bleeding
The present invention relates to methods of identifying individuals at risk of perioperative myocardial injury, major adverse cardiac events, cognitive decline, arrhythmias, depression and bleeding. |
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US20100088778 |
Methods of Treatment, and Diagnosis of Epilepsy by Detecting Mutations in the SCN1A Gene
A method for the diagnosis of an epilepsy syndrome, including SMEI or an SMEI-related syndrome, in a patient comprising testing for an alteration in the SCN1A gene in a sample obtained from the... |
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US20090233300 |
Markers for Diagnosis of Pulmonary Inflammation and Methods Related Thereto
The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel... |
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US20090246769 |
MOLECULAR DIAGNOSIS OF OVARIAN CANCERS
A molecular diagnosis system of ovarian cancers encompasses a detection device configured to obtain a detected value of an expression amount of an apolipoprotein A1 gene in ovarian tissue as a... |
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US20080102467 |
METHODS TO IDENTIFY PATIENTS AT RISK OF DEVELOPING ADVERSE EVENTS DURING TREATMENT WITH ANTIDEPRESSANT MEDICATION
The invention provides a method of screening patients to identify those patients more likely to exhibit an increased risk of treatment-emergent suicidal ideation comprising: (a) obtaining a sample... |
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US20080008993 |
Use Of A Type III Restriction Enzyme To Isolate Identification Tags Comprising More Than 25 Nucleotides
The type III restriction enzyme EcoP15I is used to isolate from cDNA of an expressed gene a tag comprising more than 25 nucleotides and capable of identifying the expressed gene, wherein the 3′... |
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US20060286090 |
Mediators of epithelial adhesion and their role in cancer and skin disorders
Perp is shown to mediate stratified epithelial development in vivo. Perp localizes specifically to desmosomes, adhesion junctions important for tissue integrity. In some embodiments of the... |
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US20090035329 |
DIAGNOSTIC AND TREATMENT METHODS FOR CHARACTERIZING BACTERIAL MICROBIOTA IN SKIN CONDITIONS
The present invention relates to methods for characterization of bacterial skin microbiota to provide diagnostic, therapeutic, and preventive measures for alleviating skin conditions. In certain... |
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US20070077554 |
Homologous viral internal controls for use in RT-PCR assays of enteric viruses
Homologous viral internal controls have been developed for use in RT-PCR assays of a number for viruses. Two of these internal controls, such as for HAV and Norwalk virus, are cloned on a single... |
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US20100028881 |
EXTRACELLULAR AND MEMBRANE-ASSOCIATED PROSTATE CANCER MARKERS
This document relates to methods and materials involved in identifying, assessing, and monitoring prostate cancer in male mammals. For example, this document provides arrays for detecting... |
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US20110061118 |
VECTORS AND METHODS FOR GENERATING VECTOR-FREE INDUCED PLURIPOTENT STEM (IPS) CELLS USING SITE-SPECIFIC RECOMBINATION
The present invention relates to a DNA molecule comprising: (a) a first DNA sequence comprising: (aa) a coding sequence giving rise upon transcription to a factor that contributes to the... |
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US20080187512 |
Treatment for spinal muscular atrophy
Compositions for treatment of spinal muscular atrophy (SMA) and methods for use thereof to treat SMA and other conditions of SMN-deficiency; novel drug development targets for SMA therapies, and... |
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US20100159453 |
GENES INVOLVED IN INTESTINAL INFLAMMATORY DISEASES AND USE THEREOF
The invention concerns genes involved in inflammatory and/or immune diseases and some cancers, in particular intestinal cryptogenic inflammatory diseases, and proteins coded by said genes. The... |
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US20100184050 |
DIAGNOSIS AND TREATMENT OF INFLAMMATORY BOWEL DISEASE IN THE PUERTO RICAN POPULATION
This invention provides methods of diagnosis and treatment of inflammatory bowel disease. In one embodiment, the invention provides methods of diagnosing and/or predicting susceptibility for... |
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US20090263793 |
NOVEL METHOD FOR DIAGNOSING OF MYCOBACTERIUM Tuberculosis
The present invention relates to a method and a kit for detecting Mycobacterium tuberculosis (MTB) or Nontuberculous mycobacteria (NTM) of patients. The present invention also relates to primers... |
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US20090110639 |
PREDICTING VACCINE EFFICACY
The present invention provides methods for evaluating a vaccine, combinations of tests and reaction mixtures that can be used as part of such methods, and collections of results comprising results... |
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US20110076272 |
THERAPEUTIC METHODS AND COMPOSITIONS
Disclosed herein are methods for modulating the environment of a tumor, by inhibiting the activity of the extracellular enzyme lysyl oxidase-like 2 (LOXL2). The methods disclosed herein are... |
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US20100285045 |
Novel Neurotrophic Factor Protein and Uses Thereof
The present invention discloses a novel neurotrophic factor protein, MANF2 and a genetic sequence encoding the same. The molecule will be useful in the development of a range of therapeutics and... |
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US20100293665 |
Plants With Increased Yield (KO NUE)
This invention relates generally to transformed plant cells and plants or parts thereof comprising an inactivated or down-regulated gene resulting an increased yield, in particular an increased... |
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US20100167300 |
MICROENVIRONMENT NICHE ASSAY FOR CiPS SCREENING
The present invention provides three-dimensional microenvironment niches prepared from biomaterial compositions that supports growth and self renewal of stem cells. The invention also provides... |
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US20100261188 |
NON-INVASIVE PRENATAL GENETIC SCREEN
The present invention provides methods and kits useful for genetic testing or screening of fetuses using nucleic acid samples isolated from cervical mucus samples of fetus hosts. |