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US20060063727 |
Tr4/tr2 response elements
Disclosed are compositions and methods related to TR2 and TR4. |
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US20090111116 |
Method for monitoring the efficacy of a mycobacterium avium subspecies paratuberculosis therapy
The present invention relates to Mycobacterium avium subspecies paratuberculosis (MAP) as the etiological agent of IBD, including ulcerative colitis and Crohn's disease, as well as Multiple... |
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US20090148458 |
COAGULATION FACTOR III POLYMORPHISMS ASSOCIATED WITH PREDICTION OF SUBJECT OUTCOME AND RESPONSE TO THERAPY
The invention provides methods and kits for obtaining a prognosis for a subject having or at risk of developing an inflammatory condition or hypertension. The method generally comprises... |
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US20080159983 |
Interleukin-15 antagonists for the treatment of anemia
The present invention relates to methods and compositions for the prevention and treatment of anemia. Anemia is characterized by a deficiency in red blood cells (RBCs) or hemoglobin, thereby... |
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US20050170383 |
Microarray hybridization assembly using a heat shrinkage bag for sealing the reaction region
A microarray hybridization assembly for conducting hybridization assay analysis is disclosed. The microarray assembly comprises a slide, a slide cover, and a spacer disposed between the slide and... |
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US20070172877 |
Methods for preventing cattle reproductive diseases
The present invention relates to methods for treating or preventing diseases or disorders in a pregnant cow and calf nursing a pregnant cow caused by infection by Bovine Viral Diarrhea Virus... |
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US20110086765 |
GENE EXPRESSION PROFILING OF PRIMARY BREAST CARCINOMAS USING ARRAYS OF CANDIDATE GENES
Method for molecular characterization of a carcinoma including: (i) detecting in tumor cells corresponding to breast tumor cells at least one polynucleotide selected from a first group determining... |
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US20100184040 |
COMPOSITIONS AND METHODS FOR DETERMINING LIKELIHOOD OF TWINNING
Collections of polynucleotides useful for estimating breeding value or detecting likelihood of twinning are disclosed. The polynucleotides are used to detect genomic sequences quantitatively... |
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US20070134652 |
Multiplexed quantitative detection of pathogens
The invention allows for the quantitative detection of a plurality of pathogens in a single sample. The method includes the amplification of a sample with a plurality of pathogen-specific primer... |
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US20110020814 |
METHODS AND COMPOSITIONS FOR SELECTION OF STEM CELLS
Described herein are methods and compositions for selection of pluripotent stem cells from a population of mammalian cells (e.g., human) undergoing a process that induces some cells within the... |
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US20100292170 |
METHODS FOR DIAGNOSING AND TREATING PELVIC PAIN DISORDERS VIA BETA-CATENIN
Methods for diagnosing a pelvic pain disorder that include analyzing samples for increased levels and/or nuclear accumulation of beta-catenin, which indicates presence of the pelvic pain disorder,... |
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US20100144903 |
METHODS OF DIAGNOSIS AND TREATMENT OF CROHN'S DISEASE
In one embodiment, this invention provides methods of diagnosing and/or predicting susceptibility to Crohn's Disease by determining the presence or absence of risk haplotypes in IL23R, IL17A,... |
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US20050106577 |
Cleavable solid phases for isolating nucleic acids
Solid phase materials for binding nucleic acids and methods of their use are disclosed. The materials feature a cleavable linker portion which can be cleaved to release bound nucleic acids. The... |
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US20090298711 |
VASOPRESSIN PATHWAY POLYMORPHISMS AS INDICATORS OF SUBJECT OUTCOME IN CRITICALLY ILL SUBJECTS
The invention provides methods, nucleic acids, compositions and kits for predicting a subject's response to treatment with one or more vasopressin receptor agonists to identify subjects having a... |
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US20110008769 |
DOPAMINERGIC NEURON PROGENITOR CELL MARKER 187A5
An object of the present invention is to provide a probe, a primer, a primer set and an antibody for use in the detection or selection of a dopaminergic neuron progenitor cell. The present... |
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US20090239225 |
PREDICTION AND DIAGNOSIS OF CANINE DEGENERATIVE MYELOPATHY
The present invention provides for methods of identifying a dog carrying a major genetic risk factor in the SOD1 gene for degenerative myelopathy, a potential model for human amyeotrophic lateral... |
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US20100209923 |
Probe for diagnosis of marfan syndrome and a method for screening using the probe
The purpose of this invention is to provide a probe for diagnosis of Marfan syndrome, which enables early diagnosis of Marfan syndrome, and to provide a method for screening using said probe. The... |
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US20090048194 |
Vagal Afferent Neurons as Targets for Treatment
A method of identifying a compound capable of reducing or preventing prolonged sensory neuron hyper-excitability comprising the steps of: (a) administering the compound to an experimental... |
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US20060263813 |
Methods of monitoring functional status of transplants using gene panels
Methods useful in monitoring the functional status of a transplant in a patient by detecting the expression levels of gene panels are described herein. Algorithms for analysis of the expression... |
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US20070269827 |
Predicting and Diagnosing Patients With Autoimmune Disease
The present invention provides methods for the prediction and diagnosis of autoimmune diseases including Systemic Lupus Erythematosus using a panel of single nucleotide polymorphisms (SNPs). |
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US20110065103 |
USE OF RNA FOR REPROGRAMMING SOMATIC CELLS
The present invention provides methods for de-differentiating somatic cells into stem-like cells without generating embryos or fetuses. More specifically, the present invention provides methods... |
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US20070178438 |
Apolipoprotein c-1 induced apoptosis
The present invention provides methods and compositions for identifying compounds which inhibit ApoCI and which are useful in the treatment or prevention of atherosclerosis, plaque rupture,... |
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US20100278800 |
Stem cell factor-like proteins and uses thereof
The invention relates to pharmaceutical compositions comprising gastrointestinal proliferative factor SCFA2, SCFA4 or SCFA4v polynucleotides and polypeptides. The invention further relates to the... |
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US20060160119 |
Genetic screening for improving treatment of patients diagnosed with depression
Disclosed is a method for screening patients to determine whether or not SSRI therapy is likely to alleviate symptoms of depression in those patients. The method provides a polymorphism at... |
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US20100297621 |
USE OF PRE-MRNA SPLICING IN PLATELET CELLS FOR THE DIAGNOSIS OF DISEASE
The invention relates to materials and procedures for identifying or using tissue factor (TF) pre-mRNA splicing, CIk 1 activity or TF-dependent coagulation in platelet cells for the diagnosis,... |
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US20100310450 |
METHOD OF DIAGNOSIS AND AGENTS USEFUL FOR SAME
The present invention relates generally to a method of screening for a neoplastic cell in a subject. More particularly, the present invention provides a method of screening for both viable... |
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US20100278866 |
BORRELIA DIAGNOSTICS AND SCREENING METHODS
Compositions and methods of detecting Borrelia proteins, nucleic acid sequences encoding these proteins, and subject antibodies to these proteins in a sample are disclosed. |
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US20090300794 |
Manipulation Of The Nitrogen Metabolism
The present invention relates to the manipulation of the nitrogen metabolism in photosynthetic active organisms, preferably in plants. In particular, the present invention relates to a process for... |
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US20100047807 |
GENETIC VARIANTS ASSOCIATED WITH PERIODIC LIMB MOVEMENTS AND RESTLESS LEGS SYNDROME
The present inventions discloses genetic markers and haplotypes that have been found to be associated with risk of Restless Legs Syndrome (RLS), Periodic Limb Movement Disorder (PLMD), and... |
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US20110046204 |
Human Zip1, Zinc and Citrate for Prostate Cancer Screening
The present invention provides methods of detecting prostate cancer employing biomarkers, including hZIP1, zinc and citrate. Also provided are antibodies to detect hZIP1 protein or peptides and an... |
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US20110086340 |
METHODS, DEVICES, KITS AND COMPOSITIONS FOR DETECTING ROUNDWORM
Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a mammalian sample are disclosed herein. The methods, devices, kits and compositions of the present... |
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US20080003603 |
HUMAN MELANOMA MUTATION
The present invention relates to the field of melanoma diagnosis and therapy. In particular, the present invention relates to c-kit activating mutations present in melanoma, and their use for... |
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US20080057583 |
Reverse Progeny Mapping
Provided is a method for mapping traits in organisms, in particular in plants. The method comprises a) providing a population of SDR-0 organisms, in particular plants, that each arise from one... |
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US20050142547 |
Diagnosis of vascular disease susceptibility using bacteriophage phi-cpn1 host chlamydia
Methods are provided for determining susceptibility of a patient to vascular disease according to presence of chlamydia infected with bacteriophage ΦCpn1, and compositions for use in such methods.... |
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US20110071031 |
COMPOSITIONS, METHODS, AND KITS FOR ISOLATING AND ANALYZING NUCLEIC ACIDS USING AN ANION EXCHANGE MATERIAL
The present disclosure relates to methods for isolating, amplifying, and/or analyzing nucleic acids in the presence of an anion exchange material by performing the isolation, amplification and/or... |
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US20060246439 |
Methods to predict cholesterol elevations during immunosuppressant therapy
This invention provides methods to predict the degree of elevation of serum cholesterol levels in patients treated with immunosuppressive medication. This invention also provides treatment... |
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US20100099101 |
METHODS FOR TREATING, DIAGNOSING, AND MONITORING LUPUS
Methods of identifying, diagnosing, and prognosing lupus, including certain subphenotypes of lupus, are provided, as well as methods of treating lupus, including certain subpopulations of... |
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US20070037164 |
Tumor necrosis factor alpha
The present disclosure describes the use of genetic variance information for genes involved in inflammatory or immunologic disease, disorder, or dysfunction. The variance information is indicative... |
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US20090148463 |
IVIG MODULATION OF CHEMOKINES FOR TREATMENT OF MULTIPLE SCLEROSIS, ALZHEIMER'S DISEASE, AND PARKINSON'S DISEASE
The present invention provides methods for providing a prognosis of treatment of diseases associated with inflammatory disease of the brain, including MS, e.g., relapsing-remitting multiple... |
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US20080317749 |
Use of Cytokine Expression to Predict Skin Inflammation; Methods of Treatment
Provided are methods for diagnosing the propensity of a subject to develop skin inflammation, in particular, psoriasis. Also provided are methods of treatment with antagonists of IL-17, IL-19,... |
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US20110008777 |
PD-1 MODULATION AND USES THEREOF
Reagents, kits, methods and uses thereof useful for the modulation of immune function, such as the identification of modulators of PD-1 activity, are described. Such reagents, kits, methods and... |
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US20100105046 |
METHODS OF DIAGNOSING CARDIOVASCULAR DISEASE
The invention relates to predicting which individuals are at risk of developing atherosclerotic vascular disease, and once having disease, which individuals are at risk of experiencing plaque... |
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US20060014195 |
Investigation of DNA samples
A method of investigating a DNA sample is provided involving taking at least two sub-samples from the sample, amplifying the sub-samples, analysing the sub-samples to obtain identity information... |
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US20100168211 |
HEREDITARY CATARACT STATUS IN CANINES BASED ON HSF4 GENE MARKER
The invention provides methods for assessing the Hereditary cataract (HC) status of a canine mammal, which methods comprise use of an HSF4 marker to assess the status. Preferred canine mammals are... |
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US20100221719 |
Probes for detecting protein nuclear transport and method for detecting and quantifying protein nuclear transport using the same
A convenient and highly accurate method for detecting protein nuclear transport induced by an endogenous or exogenous substance in local areas of living cells or animals is provided. The method... |
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US20110092572 |
MODULATION OF GROWTH HORMONE RECEPTOR EXPRESSION AND INSULIN-LIKE GROWTH FACTOR EXPRESSION
Compounds, compositions and methods are provided for modulating the expression of growth hormone receptor and/or insulin like growth factor-I (IGF-I). The compositions comprise oligonucleotides,... |
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US20100227330 |
METHODS FOR DIAGNOSING EPISODIC MOVEMENT DISORDERS AND RELATED CONDITIONS
The present invention provides compositions and methods for research, diagnostic, drug screening, and therapeutic applications related to paroxysmal dystonic choreoathetosis and related... |
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US20100273663 |
Methods and compositions related to arrhythmogenic right ventricular cardiomyopathy (ARVC)
This disclosure provides the identification of an eight base pair deletion in the 3′-untranslated region (UTR) of the striatin gene that is linked to arrhythmogenic right ventricular... |
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US20070020623 |
Method for determining homeostasis of the skin
Described herein are processes and devices useful for the identification of genes differentially expressed in skin. Preferably, the processes and devices are useful for the in vitro determination... |
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US20100047240 |
Metastasis specific splice variants of mena and uses thereof in diagnosis, prognosis and treatment of tumors
Methods and kits for diagnosis, prognosis and treatment of metastatic tumors are provided where the metastatic tumor is characterized by changes in expression of +++, ++ and/or 11a variants of Mena. |