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US20100304978 Methods and compositions for identifying a fetal cell  
The present invention provides methods and compositions for specifically identifying a fetal cell. An initial screening of approximately 400 candidate genes by digital PCR in different fetal and...
US20110020800 Characterization of BBK07 antigen of Borrelia burgdorferi and methods of use  
In this application is described the characterization Borrelia burgdorferi lipoprotein BBK07, an in vivo expressed and surface-exposed immunogen. BBK07 expression in the infected hose can be...
US20060166219 NTRK1 genetic markers associated with progression of Alzheimer's disease  
Haplotypes in the NTRK1 gene associated with progression of Alzheimer's Disease are disclosed. Compositions and methods for detecting these NTRK1 haplotypes are disclosed.
US20050255492 CHRNA9 genetic markers associated with progression of Alzheimer's disease  
Haplotypes in the CHRNA9 gene associated with progression of Alzheimer's Disease are disclosed. Compositions and methods for detecting these CHRNA9 haplotypes are disclosed.
US20050250122 APOA4 genetic markers associated with progression of Alzheimer's disease  
Haplotypes in the APOA4 gene associated with progression of Alzheimer's Disease are disclosed. Compositions and methods for detecting these APOA4 haplotypes are disclosed.
US20050250121 NTRK2 genetic markers associated with progression of Alzheimer's disease  
Haplotypes in the NTRK2 gene associated with progression of Alzheimer's Disease are disclosed. Compositions and methods for detecting these NTRK2 haplotypes are disclosed.
US20100166783 METHOD  
Gene expression profiles, microarrays comprising nucleic acid sequences representing gene expression profiles, and new diagnostic kits and methods are provided. The gene expression profiles,...
US20090264779 PREDICTING RISK OF MAJOR ADVERSE CARDIAC EVENTS  
Measurement of circulating ST2 and natriuretic peptide (e.g., NT-proBNP) concentrations is useful for the prognostic evaluation of subjects, in particular for the prediction of adverse clinical...
US20110092446 COMPOSITIONS AND METHODS FOR TREATMENT OF TRAUMA  
The present invention features the use of a complement inhibitor, e.g., a compstatin analog for treating an individual who has suffered a severe injury. In some embodiments, the complement...
US20060141460 Assays for fprl-1 ligands  
Assays for screening for compounds that act as agonists, antagonists, or inverse agonists of CKβ8-1 at the FPRL-1 receptor.
US20070077555 Adsorption system for the removal of viruses and viral components from fluids, in particular blood and blood plasma  
The present invention relates to an adsorption system for the removal of viruses and viral components, in particular hepatitis C viruses, from physiological fluids, in particular whole blood or...
US20070134690 Diagnosis of systemic onset juvenile idiopathic arthritis through blood leukocyte microarray analysis  
The present invention includes compositions, systems and methods for the early detection and consistent determination of systemic onset juvenile idiopathic arthritis (SoJIA) using microarrays.
US20100203530 Systems for genome selection  
Systems, methods, compositions and apparatus relating to genome selection are disclosed.
US20100062444 TLE3 AS A MARKER FOR CHEMOTHERAPY  
Methods of using TLE3 as a marker for predicting the likelihood that a patient's cancer will respond to chemotherapy. Methods of using TLE3 as a marker for selecting a chemotherapy for a cancer.
US20100166880 Method for treatment and diagnosis of glutamate dehydrogenase disorders  
Methods and compositions for diagnosis and treatment of neurodegenerative disorders are disclosed. The methods and compositions apply the discovery of the correlation between an hGDH2 gene...
US20050112649 Sensitive and self-calibrating multi-test system the detection and identification of enterohemorrhagic escherichia coli (EHEC)  
We propose a novel high sensitivity multi-test detection and identification system for EHEC. The integrated testing system uses, in a single run, multiple molecular signatures and receptor...
US20090215053 Vitro Method for the Prognosis of Progression of a Cancer and of the Outcome in a Patient and Means for Performing Said Method  
The present invention relates to the prognosis of the outcome of a cancer in a patient, which prognosis is based on the quantification of one or several biological markers that are indicative of...
US20110064721 CATHEPSIN-D NEUROPROTECTION  
Provided herein are methods and compositions for promoting neuroprotection in a subject and for treating a neural disorder associated with protein aggregation comprising administering to the...
US20050196773 Predicting upper aerodigestive tract cancer  
Cancer screening models based on analysis of mass spectroscopy data can be used to predict upper aerodigestive tract cancer, including lung and head and neck cancers. Models can be generated by...
US20060177821 Association of the h2 haplotype of the p2y12 receptor with an increased risk for thrombosis and peripheral arterial disease  
The invention relates to an in vitro method for determining the risk of developing thrombosis in a subject, and to an in vitro method for determining sensitivity of a subject toward a...
US20100190172 GENETIC POLYMORPHISMS ASSOCIATED WITH CARDIOVASCULAR DISORDERS AND DRUG RESPONSE, METHODS OF DETECTION AND USES THEREOF  
The present invention is based on the discovery of genetic polymorphisms that are associated with cardiovascular disorders, particularly acute coronary events such as myocardial infarction and...
US20110059447 METHOD FOR THE DETECTION OF GENE TRANSCRIPTS IN BLOOD AND USES THEREOF  
The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and...
US20110008780 METHOD FOR THE DETECTION OF GENE TRANSCRIPTS IN BLOOD AND USES THEREOF  
The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and...
US20110003298 METHOD FOR THE DETECTION OF GENE TRANSCRIPTS IN BLOOD AND USES THEREOF  
The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and...
US20110003297 METHOD FOR THE DETECTION OF GENE TRANSCRIPTS IN BLOOD AND USES THEREOF  
The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and...
US20110003296 Method for the detection of gene transcripts in blood and uses thereof  
The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and...
US20110033858 siRNA DETECTION METHOD  
PolydG is added to the terminal overhangs of an siRNA. Next, a primer containing a polydC sequence added with a tag sequence is annealed and cDNA is synthesized by a reverse transcription...
US20090311684 ENHANCED FC RECEPTOR-MEDIATED TUMOR NECROSIS FACTOR SUPERFAMILY AND CHEMOKINE MRNA EXPRESSION IN PERIPHERAL BLOOD LEUKOCYTES IN PATIENTS WITH RHEUMATOID ARTHRITIS  
A method for predicting patient responsiveness to rheumatoid arthritis treatments involving altering expression of TNFSF-3, TNFSF-4, TNFSF-7, TNFSF-11, or TNFSF-14 is disclosed. A method for...
US20070042368 Detection and monitoring of lung cancer  
Compositions and methods for the diagnosis of lung cancer are disclosed. Such methods are useful to detect early tumors or provide adequate stage/grade information or tumor specificity....
US20090035279 GENETIC VARIANTS ON CHR 15Q24 AS MARKERS FOR USE IN DIAGNOSIS, PROGNOSIS AND TREATMENT OF EXFOLIATION SYNDROME AND GLAUCOMA  
The present invention relates to methods of diagnosing a susceptibility to an ocular disorder, including glaucoma and exfoliation syndrome. The invention provides methods of diagnosing an...
US20090325911 Use of Androgens for the Treatment of Parkinson's Disease  
The invention generally provides therapeutic and prophylactic methods relating to the use of androgens for the treatment of Parkinson's disease or other neurodegenerative diseases. In addition,...
US20080020387 BIOMARKER-OPTIMIZED ADHD TREATMENT  
Methods of predicting patient responsiveness to treatment of attention-deficit/hyperactivity disorder (ADHD) with selective norepinephrine reuptake inhibitors; identifying individuals requiring a...
US20100254991 Use of Cytokine Expression to Predict Skin Inflammation; Methods of Treatment  
Provided are methods for diagnosing the propensity of a subject to develop skin inflammation, in particular, psoriasis. Also provided are methods of treatment with antagonists of IL-17, IL-19,...
US20090104620 Simplified Method of Determining Predisposition to Scoliosis  
The present invention relates to novel genetic markers associated with scoliosis, risk of developing scoliosis and risk of scoliosis curve progression, and simplified methods and materials for...
US20090130673 Methods for detecting and differentiating mycobacterium genus and mycobacterium avium complex in a sample or culture  
The present invention relates to compositions and methods for detecting Mycobacterium genus (Mycobacterium sp.) bacteria (e.g., M. tuberculosis) and M. avium complex (MAC; M. avium, M....
US20060210974 Compositions and methods for preventing, treating and diagnosing diabetes  
The invention provides methods and compositions for preventing, treating and diagnosing diabetes.
US20110065105 Novel transcription factor-based biosensor  
The present invention provides for a system comprising a BmoR transcription factor, a σ54-RNA polymerase, and a pBMO promoter operatively linked to a reporter gene, wherein the pBMO promoter is...
US20100016938 DIAGNOSING, MONITORING AND TREATING INFLAMMATION  
The present invention provides methods and compositions for treating chronic inflammatory disease in a subject and associated pharmaceutical compositions, medical devices and systems.
US20090035284 DERIVATION OF NEURAL STEM CELLS FROM EMBRYONIC STEM CELLS AND METHODS OF USE THEREOF  
Provided is a method for the derivation of neural stem cells (NSCs) from embryonic stem cells (ESCs) and the use of the NSCs for treatment of various neural disorders. The NSCs that are derived...
US20050095592 Identification of ovarian cancer tumor markers and therapeutic targets  
The present disclosure provides methods for classifying ovarian tumors into BRCA1-type, BRCA2-type or non-BRCA-type tumor types by measuring expression levels of a plurality of disclosed ovarian...
US20100062424 Assessment of Infectious Bacteria  
Disclosed herein are methods for determining whether an opportunistic bacterium is infectious.
US20100330066 Methods for Use with Baff Antagonists  
BAFF plays a central role in acquired immunity. The disclosure identifies BAFF-responsive genes that are substantially upregulated by administration of BAFF and substantially downregulated by...
US20070141585 Altered gene expression profiles in stable versus acute childhood asthma  
Differences in gene expression in control and asthma patients to profile, differentiate, evaluate, etc. patients with exacerbated asthma and stable asthma.
US20090264507 METHOD OF DIAGNOSING GUM DISEASE-WOUND HEALING USING SINGLE NUCLEOTIDE POLYMORPHISM PROFILES  
The present invention provides methods for diagnosing and providing a prognosis for wound healing in a patient by characterizing and analyzing the single nucleotide polymorphism (SNP) of a wound...
US20080268430 Methods and Kits Pertaining to the Detection, Identification and Quantification of Bacteria and Yeast in Wine, Beer and Juices  
The invention concerns new analytical methods for detecting and identifying qualitatively and quantitatively germ contaminations, e.g. bacterial and yeast contaminations usings specific DNA...
US20100048687 USE OF PHOSPHATASE INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES  
Provided are novel a target and drugs in the treatment of neurological disorders related to amyloid beta pathology/amyloidosis. More specifically, the use of phosphatase inhibitors for the...
US20090131348 MICRORNAS DIFFERENTIALLY EXPRESSED IN PANCREATIC DISEASES AND USES THEREOF  
The present invention concerns methods and compositions for identifying a miRNA profile for a particular condition, such as pancreatic disease, and using the profile in assessing the condition of...
US20090035768 Method of Determining Predisposition to Scoliosis and Uses Thereof  
The present invention relates to novel genetic markers associated with scoliosis, risk of developing scoliosis and risk of scoliosis curve progression, and methods and materials for determining...
US20110010785 PRODUCTS AND THEIR USE FOR THE DIAGNOSIS, PREVENTION AND/OR CARE OF HUMAN AND/OR ANIMAL PATHOLOGIES CHARACTERISED BY THE ANOMALOUS DEPOSITION OF B-AMYLOID AND/OR AMYLOID-LIKE SUBSTANCE IN HUMAN AND/OR ANIMAL ORGANS AND TISSUES, AND SCREENING METHOD FOR DETERMINING THE RISK OF SUCH PATHOLOGIES  
The patent refers to a screening method carried out on biological material isolated from human and/or animal organisms for determining the risk of human and/or animal pathologies expressing an...
US20050208544 Diagnostic tests for the detection of peripheral neuropathy  
The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect human peripheral neuropathy...