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US20100209413 |
SERPINE1 POLYMORPHISMS ARE PREDICTIVE OF RESPONSE TO ACTIVATED PROTEIN C ADMINISTRATION AND RISK OF DEATH
Methods, oligonucleotides arrays etc. for treating inflammatory conditions and of predicting subject outcome based on polymorphisms in SERPINE1 and/or PROC, alone or in combination, wherein the... |
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US20060068428 |
Identification of genetic markers associated with parkinson disease
The present invention provides methods and compositions for screening a subject for Parkinson disease, for increased risk of developing Parkinson disease and/or for an earlier or later age of... |
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US20100029576 |
Diazoxide for the treatment of Friedreich's Ataxia
A pharmaceutical preparation treats Friedreich's ataxia and treats or prevents pathologies related thereto. In particular, the pharaceutical preparation concerns the use of diazoxide or... |
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US20110021369 |
SINGLE CELL BASED REPORTER ASSAY TO MONITOR GENE EXPRESSION PATTERNS WITH HIGH SPATIO-TEMPORAL RESOLUTION
The invention relates to a double-stranded polynucleotide comprising on its positive strand considered from its 5′ end to its 3′ end, (i) a promoter of a gene of interest or several promoters of... |
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US20110055964 |
Method for Generating Hypermutable Plants
Blockade of mismatch repair in a plant can lead to hypermutation and a new genotype and/or phenotype. One approach used to generate hypermutable plants is through the expression of dominant... |
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US20100330044 |
MESP1 AS A MASTER REGULATOR OF MULTIPOTENT CARDIOVASCULAR PROGENITOR SPECIFICATION AND USES THEREOF
A method for differentiating or promoting or inducing differentiation of stem cells into pluripotent cardiovascular progenitors (MCPs) by transiently inducing the expression of a single gene,... |
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US20100322926 |
METHODS OF USING CADHERIN 11 (CDH11) ANTAGONISTS
The present invention provides novel methods of inhibiting or preventing epithelial-mesenchymal transition (EMT) or endothelial-mesenchymal transition (EnMT), such as EMT or EnMT, associated with... |
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US20100311068 |
ASSAY
The invention relates to process for in vitro prediction of a potentially allergenic substance wherein monocytes and/or macrophages and/or myelomonocytic cell lines are cultivated in the presence... |
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US20100310533 |
METHODS OF USING IL-21 FOR ADOPTIVE IMMUNOTHERAPY AND IDENTIFICATION OF TUMOR ANTIGENS
Methods for preparing ex vivo T cell cultures using IL-21 compositions for use in adoptive immunotherapy are described. Addition of IL-21 to cultures of non-terminally differentiated T cells... |
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US20100317011 |
Proteins having serine/threonine kinase domains, corresponding nucleic acid molecules, and their use
The invention relates to the molecule referred to as ALK-1, and its role as a type I receptor for members of the TGF-β family. The molecule has a role in the phosphorylation of Smad-5 and Smad1,... |
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US20070059720 |
RNA expression profile predicting response to tamoxifen in breast cancer patients
The present invention regards predicting a response to a therapy using RNA expression profiling. In particular, a resistance to a chemotherapy, such as tamoxifen, is predicted by comparing... |
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US20070105123 |
IRE-1alpha substrates
IRE-1α substrates useful for identifying agonists and antagonists of IRE-1α RNase activity. |
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US20090042194 |
Predicting a response to risperidone
The invention relates generally to the relative effect of specific genetic polymorphisms in predicting the clinical outcome of risperidone therapy in patients suffering from a psychiatric disease... |
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US20050037374 |
Combined nanotechnology and sensor technologies for simultaneous diagnosis and treatment
Systems and methods for diagnosing and/or treating conditions, diseases, or disorders. The present invention uses nanoparticle-based assemblies, which comprise a nanoparticle; a surrogate marker;... |
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US20050201937 |
Temporal or spatial characterization of biosynthetic events in living organisms by isotopic fingerprinting under conditions of imposed isotopic gradients
The invention provides methods useful for establishing timing or spatial location of a biosynthetic event in a living organism, without disrupting the event of interest and without disrupting the... |
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US20100331197 |
SYSTEM AND METHOD FOR THE CLONAL CULTURE OF EPITHELIAL CELLS AND APPLICATIONS THEREOF
The invention relates to means and methods for evaluating and using the specific properties of a particular epithelial cell present in a biological sample. Accordingly, the invention relates to a... |
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US20110028453 |
Treating Negative Symptoms of Schizophrenia Associated with Defective Neuregulin 1
Use of a compound that is a serotonin transporter inhibitor, a selective norepinephrine reuptake inhibitor, or a 5-HT1A agonist for alleviating negative symptoms in a schizophrenia patient who... |
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US20110033847 |
Methods for the characterization of microorganisms on solid or semi-solid media
The present invention relates to methods and systems for scanning, detecting, and monitoring microorganisms on solid or semi-solid media using intrinsic fluorescence (IF) measurements. The methods... |
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US20110086925 |
Method and System to Detect, Diagnose, and Monitor the Progression of Alzheimer's Disease
Various embodiments provide methods for the detection, the diagnosis, and/or the progression monitoring of Alzheimer's disease by observing the epigenetic markers in leukocytes. Methods for... |
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US20110059103 |
FUTURE CARDIAC EVENT BIOMARKERS
The present invention relates to the identification of chemokine biomarkers predictive of future acute coronary syndromes including unstable angina pectoris (UAP). The present invention also... |
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US20110190156 |
MOLECULAR SIGNATURES FOR DIAGNOSING SCLERODERMA
The present invention features methods for classifying, determining severity, and predicting clinical endpoints of scleroderma based upon the expression of selected biomarker genes. |
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US20060040252 |
Prognostic tests for development of dermal stretch marks and implications for the preventive treatment thereof
Various methods of assessing the regenerative potential of dermal tissue in a patient may be determined and methods to determine the potential development of stretch marks in a patient are... |
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US20080275728 |
Method for Personalized Diet Design for Females of Asian Origin
The present invention provides methods for personalized diet design for females of Asian origin, wherein females who are homozygous for the PLIN 11482A are advised to avoid diets high in fat and... |
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US20100010056 |
TREATMENT FOR NICOTINE-INDUCED LUNG DISEASE USING PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONISTS
This invention provides pertains to the discovery that that nicotine interrupts molecular signaling between endodermal and mesodermal cells of the lung alveolus. Treatment of the lung with... |
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US20060024705 |
Molecular analysis of hair follicles for disease
Methods are provided for the analysis of gene expression utilizing RNA from hair follicles. Methods are also provided for evaluation of the biological activity of a candidate substance, genetic... |
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US20080050740 |
Nutritional and Exercise Plan Based On A Person's Individual Genetic APO E Genotype
A nutritional plan based on a person's individual genetic APO E genotype, which has been shown to be the number one gene affecting diet, cholesterol, heart disease, vascular dementia, Alzheimer's... |
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US20070015172 |
Expression profiles for microbial infection
The invention provides methods for identifying markers of microbial infection, diagnosing microbial infections, and identifying the specific pathogen(s) involved in a microbial infection based on... |
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US20050112653 |
Genetic archival identity card
The invention is a device for preserving genetic material for subsequent analysis. The genetic material is encapsulated into a plastic card (the device) by a process that preserves the integrity... |
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US20050118622 |
Methods for predicting development of insulin resistance
Methods of predicting a subject's likelihood of developing insulin resistance comprise determining in a subject the identity of the nucleotide present at position 100 of SEQ ID NO 1, wherein the... |
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US20110008346 |
BIOMARKERS FOR CARDIOVASCULAR DISEASE
The present invention relates to a method of diagnosis or prognosis of cardiovascular disease in a subject, said method comprising the steps of detecting the presence of activated endothelial... |
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US20060062859 |
Composition and method to optimize and customize nutritional supplement formulations by measuring genetic and metabolomic contributing factors to disease diagnosis, stratification, prognosis, metabolism, and therapeutic outcomes
The present invention relates to a composition and custom business model and methods to measure genetic and metabolomic contributing factors affecting disease diagnosis, stratification, and... |
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US20110059113 |
GAB2 AMPLIFICATION IN MELANOMA
Provided herein are methods of detecting or inhibiting melanoma growth based on Gab2 protein expression. Gab2 protein was found to be either amplified and/or overexpressed in melanoma. Gab2... |
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US20100311609 |
Methylation Profile of Neuroinflammatory Demyelinating Diseases
The present invention relates to compositions and methods for diagnosing neuroinflammatory demyelinating diseases, including but not limited to, multiple sclerosis. In particular, the present... |
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US20050136444 |
Treating neuropathic pain with neuropeptide FF receptor 2 agonists
The invention described below relates to the discovery of the neuropeptide FF receptor subtype that mediates acute nociception and chronic neuropathic pain, compounds that selectively interact... |
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US20100310568 |
NINJURIN-1 MODULATION AND USES THEREOF
Methods, uses, agents and compositions useful for the prevention, treatment and/or diagnosis of neuroinflammatory conditions such as multiple sclerosis and spinal cord injury based on the... |
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US20100305103 |
GENES DIFFERENTIALLY EXPRESSED IN BIPOLAR DISORDER AND/OR SCHIZOPHRENIA
This invention provides molecular markers that are prognostic and/or diagnostic for a psychiatric disorder. In particular, genes are identified whose expression is altered in schizophrenia and/or... |
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US20110038830 |
COSMETIC USE OF PLAKOGLOBIN-TYPE PROTEINS
The present invention relates to the use, in particular cosmetic and/or therapeutic use, of plakoglobin, of polypeptides derived from this protein or of analogs thereof, of a nucleic sequence... |
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US20110003697 |
PLANT MYB TRANSCRIPTION FACTOR HOMOLOGS
This invention relates to an isolated nucleic acid fragment encoding a Myb-related transcription factor. The invention also relates to the construction of a chimeric gene encoding all or a portion... |
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US20100298280 |
Compounds for the Modulation of Huntingtin Aggregation, Methods and Means for Identifying Such Compounds
The present invention relates to tetranortriterpenoid compounds and pharmaceutical compositions thereof, which are provided for use in the treatment, diagnosis and/or prevention of trinucleotide... |
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US20110053163 |
Biomarker
The invention relates to a process for in vitro prediction of a potentially allergenic substance wherein monocytes and/or macrophages and/or myelomonocytic cell lines are cultivated in the... |
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US20100297622 |
Method for high-throughput gene expression profile analysis
The present invention embraces a method for high-throughput gene profiling with high specificity and sensitivity. With this system, >1000 mRNA species can be co-amplified using gene-specific... |
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US20070238105 |
High resolution chromosomal mapping
The present invention generally relates to spatial and structural genomic analysis compositions, which can be used for the mapping of chromosomes and structural analyses of chromosomal... |
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US20060228728 |
Genetic basis of Alzheimer's disease and diagnosis and treatment thereof
A collection of polymorphic sites having resistance or susceptibility to Alzheimer's disease is provided. The sites are useful in methods of diagnosing and treating Alzheimer's disease and related... |
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US20110104668 |
NUCLEIC ACID LIGANDS AGAINST INFECTIOUS PRIONS
The invention generally relates to nucleic acid ligands that specifically bind to infectious prions, and methods of diagnosing a transmissible spongiform encephalopathy disease in a subject. In... |
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US20100075316 |
METHOD FOR IDENTIFYING ALTERED VITAMIN D METABOLISM
A method is provided for identifying an individual as having altered vitamin D metabolism comprising analyzing a biological sample from the individual for the presence of CYP24 SNPs and/or... |
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US20110041193 |
NON-HUMAN MAMMAL MODEL OF EPILEPSY
The present invention provides a genuine epilepsy model animal as an improvement over conventional epilepsy model animals which are socalled seizures model animals mainly causing seizure attacks... |
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US20110081654 |
TRANSCRIPTIONAL PROFILING OF STEM CELLS AND THEIR MULTILINEAGE DIFFERENTIATION
The present invention concerns methods of screening cells for differentiation or de-differentiation, and/or for status as a pluripotent or multipotent (e.g., “stem”) cell, by detecting the... |
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US20110067124 |
DETECTION AND TREATMENT OF DRUG ASSOCIATED ANGIOEDEMA
The present invention relates to an in vitro method of diagnosing a drug-associated angioedema or a predisposition thereto in a subject being suspected to having developed or of having a... |
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US20110002892 |
MODULAR APTAMAR-REGULATED RIBOZYMES
An extensible RNA-based framework for engineering ligand-controlled gene regulatory systems, called ribozyme switches, that exhibit tunable regulation, design modularity, and target specificity is... |
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US20110256548 |
METHOD FOR OBTAINING PANCREATIC PROGENITOR CELL USING NEPH3
The present invention provides markers that can selectively distinguish pancreatic progenitor cells. The present invention also provides methods for distinguishing pancreatic progenitor cells by... |