|
Match
|
Document |
Document Title |
|
|
US20100130527 |
INDIVIDUALIZED CANCER TREATMENT
Methods to formulate treatments for individual cancer patients by assessing genomic and/or phenotypic differences between cancer and normal tissues and integrating the results to identify... |
|
|
US20110008795 |
MARKER FOR DETECTION OF IL-17-PRODUCING HELPER T-CELL, AND METHOD FOR DETECTION OF IL-17-PRODUCING HELPER T-CELL
Disclosed is a polynucleotide marker or a protein marker for use in the specific detection of an IL-17-producing helper T-cell (a Th17 cell). Also disclosed is a method for detecting a Th17 cell,... |
|
|
US20110014603 |
TARGETS FOR USE IN DIAGNOSIS, PROGNOSIS AND THERAPY OF CANCER
Provided herein are targets that can be used for the diagnosis, prognosis and therapy of a variety of cancers. |
|
|
US20070281303 |
DNA STORAGE AND DISPLAY VESSEL AND METHOD
A storage display vessel for biological material, including a block of, for example, glass or plastic, having at least one transparent area, and a void defining a storage area in the transparent... |
|
|
US20110212459 |
NOVEL PRESENILIN ASSOCIATED MEMBRANE PROTEIN (PAMP) AND USES THEREOF
Presenilin Associated Membrane Protein (PAMP), and nucleic acids encoding this protein, are provided. PAMP and PAMP nucleic acids provide diagnostic and therapeutic tools for evaluating and... |
|
|
US20110065114 |
STEROIDOGENESIS MODIFIED CELLS AND METHODS FOR SCREENING FOR ENDOCRINE DISRUPTING CHEMICALS
An isolated steroidogenesis modified cell comprising one or more steroid biosynthesis knock down nucleic acid operatively linked to a promoter, wherein the steroid biosynthesis knock down nucleic... |
|
|
US20110033477 |
METHOD FOR DIAGNOSING AND TREATING CHRONIC PSYCHIATRIC ILLNESSES AND MARKERS AND TARGETS FOR SUCH METHODS
The invention relates to the use of special conformers of the DISC1 protein as a marker or target for chronic psychiatric illnesses, particularly schizophrenia, bipolar disorder, or depression. |
|
|
US20100311683 |
CYTIDINE ANALOGS FOR TREATMENT OF MYELODYSPLASTIC SYNDROMES
The present invention provides methods of treating a patient having a higher risk myelodysplastic syndrome, which comprises administering to a patient having a higher risk myelodysplastic syndrome... |
|
|
US20090203539 |
Avian Sex Identification Oligonucleotides
This invention relates to a number of bird sex-identification oligonucleotides and their use in determining the sex of birds in various families. |
|
|
US20100329982 |
PARTICLES WITH INDUCIBLE CHANGE OF SHAPE
The invention relates to particles which exhibit a stimulable shape change and allow control of their uptake in active cells. The particles can be used as carrier systems for bioactive molecules... |
|
|
US20110071215 |
COMPOSITIONS AND METHODS FOR DIAGNOSIS, PROGNOSIS AND TREATMENT OF MESOTHELIOMA
Described herein are compositions and methods for the diagnosis and treatment of mesothelioma patients and the prognosis of mesothelioma patients after surgical operation. Specifically the... |
|
|
US20110111418 |
USE OF IRON-RELATED PATHWAYS AND GENES FOR TREATMENT AND DIAGNOSIS OF PARKINSON'S DISEASE
A collection of genetic variants having susceptability to, or protection from, Parkinson's Disease is provided. The variants are useful in method of diagnosing, prognosing, and treating... |
|
|
US20110091886 |
METHOD OF DISTINGUISHING INFLAMMATORY PATHOGEN CAUSING ACUTE RESPIRATORY INFECTION
Disclosed is a method of distinguishing an inflammatory pathogen causing acute respiratory infection wherein the pathogen to be distinguished is a pathogen residing in the respiratory tract, which... |
|
|
US20110003295 |
Method of profiling gene expression in a subject undergoing a treatment
The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and... |
|
|
US20110003291 |
METHOD FOR STUDYING V(D)J COMBINATORY DIVERSITY
The invention relates to a method for analysing the diversity of the catalogue of T and/or B lymphocytes in an individual, based on the amplification, from a sample, of genomic DNA fragments by... |
|
|
US20100035251 |
BioMarkers for the Progression of Alzheimer's Disease
The genetic polymorphism LRRK2 (leucine-rich repeat kinase 2)-T1602S is significantly associated with conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD), with the patients... |
|
|
US20110081648 |
Methods for diagnosing peripheral neuropathy
Genes whose expression is correlated with the presence of CIDP or vasculitic neuropathy are disclosed. Probes and sets of nucleic acids and proteins specific for these genes are described, as are... |
|
|
US20110010780 |
KCNN3 AS DIAGNOSTIC AND THERAPEUTIC TARGET FOR NEURODEGENERATIVE DISEASES
The present invention discloses a dysregulation of the KCNN3 gene and the protein products thereof in Alzheimer's disease patients and individuals being at risk of developing Alzheimer's disease.... |
|
|
US20110059852 |
COMPOSITIONS AND METHODS FOR TREATING HAEMATOLOGICAL PROLIFERATIVE DISORDERS OF MEYLOID ORIGIN
The disclosure relates to methods and compositions effective in the diagnosis, prognosis and treatment of human hematopoietic cancers. In particular, the disclosure provides tumor-associated genes... |
|
|
US20110009478 |
THERANOSTIC POLYCATION BEACONS COMPRISING OLIGOETHYLENEAMINE REPEATING UNITS AND LANTHANIDE CHELATES
The present invention relates to vehicles for delivering macromolecules into cells. More particularly, embodiments of the invention relate to compounds and methods for binding and compacting... |
|
|
US20090176206 |
Toll-like receptor 2 (tlr-2) haplotypes predict outcome of patients
The invention provides methods and kits for obtaining a prognosis for a subject having or at risk of developing an inflammatory condition and or a gram positive infection. The method generally... |
|
|
US20110053170 |
Interleukin-33 (IL-33) for the Diagnosis and Prognosis of Cardiovascular Disease
The present invention includes methods for the use of interleukin-33 (IL-33) in the diagnosis of cardiovascular conditions including acute coronary syndrome (ACS), myocardial infarction, and/or... |
|
|
US20100331206 |
COMPOSITIONS AND METHODS FOR EARLY PREGNANCY DIAGNOSIS
Pregnancy-associated glycoproteins (PAGs) are structurally related to the pepsins, thought to be restricted to the hoofed (ungulate) mammals and characterized by being expressed specifically in... |
|
|
US20110041195 |
Organisms homozygous for targeted modification
Disclosed herein are homozygously modified organisms and methods of making and using these organisms. |
|
|
US20110091869 |
METHOD FOR CULTURE OF STEM CELL
The present invention enables efficient suspension culture of stem cells in a serum-free medium by comprising a step for quickly forming a homogenous aggregate of stem cells, and provides a method... |
|
|
US20080193922 |
Methods and Compositions for Inferring Eye Color and Hair Color
Methods for inferring eye color or eye shade of an individual from a nucleic acid sample of the individual by detecting the nucleotide occurrence of an eye color related single nucleotide... |
|
|
US20060177847 |
Markers for metabolic syndrome obesity and insulin resistance
Correlations between polymorphisms and metabolic syndrome, obesity, treatment-emergent weight gain and insulin resistance are provided. Methods of diagnosing and treating metabolic syndrome,... |
|
|
US20110027234 |
METHODS FOR IDENTIFICATION AND SELECTION OF HUMAN EMBRYONIC STEM CELL DERIVED CELLS
A nucleic acid construct is disclosed, the nucleic acid comprising a polynucleotide comprising a nucleic acid sequence encoding a detectable expression product, the nucleic acid sequence being... |
|
|
US20110014601 |
Targeted Chromosomal Mutagenesis Using Zinc Finger Nucleases
The present invention provides for a method or methods of targeted genetic recombination or mutagenesis in a host cell or organism, and compositions useful for carrying out the method. The... |
|
|
US20080299125 |
Genetic basis of treatment response in depression patients
The invention provides a collection of polymorphic sites associated with response to treatment by an SSRI or placebo in depression patients. The polymorphic sites and others in linkage... |
|
|
US20110059011 |
DIAGNOSIS AND TREATMENT OF DISEASED AND DAMAGED TISSUE
The present invention relates to the diagnosis and treatment of leukemia and cardiovascular disease, as well as the detection of diseased and damaged tissue. More particularly, the present... |
|
|
US20110092428 |
DETECTING AND CONTROLLING ABNORMAL HEMATOPOIESIS
A method of detecting abnormal hematopoiesis in a subject based on abnormal expression of ZFP36L2, a method of controlling hematopoiesis in a subject altering the level or activity of ZFP36L2... |
|
|
US20090186347 |
Markers for metabolic syndrome
Correlations between polymorphisms and metabolic syndrome, insulin resistance, obesity, high blood pressure, dyslipidemia, diabetes and/or myocardial infarction are provided. Methods of diagnosing... |
|
|
US20090298082 |
BIOMARKER PANELS FOR PREDICTING PROSTATE CANCER OUTCOMES
This document provides methods and materials related to assessing male mammals (e.g., humans) with prostate cancer. For example, methods and materials for predicting (1) which patients, at the... |
|
|
US20110053850 |
DOC1 COMPOSITIONS AND METHODS FOR TREATING CANCER
A purified DOC1 polypeptide comprising a fragment of SEQ ID NO: 1 is provided, wherein the DOC1 polypeptide is not the full-length DOC1 polypeptide sequence. A method of inhibiting angiogenesis in... |
|
|
US20100330571 |
METHOD OF MEASURING ADAPTIVE IMMUNITY
A method of measuring immunocompetence is described. This method provides a means for assessing the effects of diseases or conditions that compromise the immune system and of therapies aimed to... |
|
|
US20110020802 |
NUCLEIC ACIDS, METHODS AND KITS FOR THE DIAGNOSIS OF DYT6 PRIMARY TORSION DYSTONIA
The invention relates generally to the THAP1 gene and mutations in this gene, as well as the THAP1 protein and mutations in this protein, that are associated with dystonia. The invention relates... |
|
|
US20100311067 |
DETECTION OF MATERNAL ALCOHOL EXPOSURE
The present invention provides methods, compositions, and systems for detecting in utero alcohol exposure by detecting expression level changes in certain biomarkers (e.g., in placental tissue).... |
|
|
US20110111419 |
Copy Number Variations Predictive of Risk of Schizophrenia
The present invention relates to genomic copy number variations as risk factors for schizophrenia. The invention provides methods and kits for risk management of schizophrenia, by assessing such... |
|
|
US20110009288 |
METHODS AND REAGENTS FOR THE EARLY DETECTION OF MELANOMA
An assay for identifying early stage malignant melanocyte in biopsy tissues is provided by determining whether differential expression of a particular gene indicative of melanoma exceed a cut-off... |
|
|
US20060105357 |
Tissue sensor and uses thereof
Described are assemblies for screening a compound for bioactivity, the assemblies comprising a tissue and a sensor. A change in a biological parameter is measured by the sensor, such that a change... |
|
|
US20100298304 |
DIAGNOSIS AND TREATMENT OF AUTISM SPECTRUM DISORDERS
The invention relates to methods for diagnosis and treatment of autism spectrum disorders, particularly for autism spectrum disorders characterized by increased head size (circumference) and... |
|
|
US20100317003 |
NOVEL COMPOSITIONS AND METHODS IN CANCER WITH ALTERED EXPRESSION OF KCNJ9
The present invention relates to novel sequences for use in diagnosis and treatment of carcinomas, especially breast cancers. In addition, the present invention describes the use of novel... |
|
|
US20110200564 |
DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE (AD)
Disclosed herein are novel methods, assays and systems for detecting an increased risk for Alzheimer's disease (AD) in a subject by identifying at least one nuclei acid polymorphism described... |
|
|
US20110065086 |
Methods of producing homogeneous plastic-adherent aptamer-magnetic bead-fluorophore and other sandwich assays
Methods are described for assembly of DNA aptamer-magnetic bead (“MB”) conjugate plus aptamer-quantum dot (“QD”) aptamer-fluorescent nanoparticle or other aptamer-fluorophore,... |
|
|
US20050239066 |
Support for ligand immobilization
A support for ligand immobilization coated with a polyanion which has been activated beforehand. |
|
|
US20100323366 |
Methods of Selecting a Dopaminergic Neuron Proliferative Progenitor Cells Using LRP4/CORIN Markers
In neuron transplantation therapy, in terms of safety, it is preferable to use a cell population consisting only of a desired type of cells, and to use postmitotic neurons in consideration to... |
|
|
US20100249065 |
Biomarkers for Assessing Peripheral Neuropathy Response to Cancer Treatment
The present invention provides methods for identifying patients at increased risk of developing an adverse neurological event in response to a cancer treatment. Methods also include modifying the... |
|
|
US20090305233 |
Methods and Reagents for Polynucleotide Assembly
The present invention provides methods, compositions, and kits for polynucleotide assembly. |
|
|
US20100311666 |
COSMETIC USE OF A PROTEIN BELONGING TO THE RIBONUCLEASE FAMILY
The present invention relates to the use, in cosmetics and in therapeutics, of at least one antimicrobial protein belonging to the ribonuclease family, ribonuclease 7, or of polypeptides derived... |