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US20100048680 |
Alpha-1-Antitrypsin Variants and Uses Thereof
The subject invention is directed to novel polynucleotides and polypeptides comprising SEQ ID NOs: 1 and 2. Also provided arc fragments these polypeptides. The polynucleotides and polypeptides... |
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US20080131441 |
Methods of Using FOXP3 Levels to Predict the Outcome of Organs Undergoing Acute Rejection
A method for assessing risk of losing a transplanted organ by a patient having an episode of acute rejection of the transplanted organ is described. The method includes obtaining from the patient... |
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US20060099600 |
Novel acetylcholine transporter
This invention provides novel acetylcholine transporters. The transporters are effective and useful targets to screen for modulators of cholinergic synaptic activity. Also provided are methods of... |
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US20100129826 |
Double stranded RNA receptor (dsRNA-R) and methods relating thereto
The present invention is directed to nucleic acid molecules and polypeptides encoding a dsRNA receptor (dsRNA-R). The dsRNA-R contains a THD, interacts with the MyD88 adapter protein, and may bind... |
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US20050053946 |
Method for analyzing activation pathways controlled by neurotransmitters
The invention pertains to a novel method for analyzing activation pathways controlled by neurotransmitters and to a micro-array for use in this method. In particular, the present method relates to... |
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US20070128594 |
Protein c polymorphisms
The invention provides methods and kits for obtaining a prognosis for a patient having or at risk of developing an inflammatory condition. The method generally comprises determining a protein C... |
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US20100203525 |
DETECTION OF GENE DUPLICATIONS
Methods of detecting a candidate genetic anomaly such as a candidate duplication in a genome are disclosed. The methods comprise quantifying fluorogenic assays for alleles of a genetic locus from... |
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US20070172845 |
Nucleic Acid Probes and Microarrays for Analysis of Polynucleotides
The invention provides a probe for detecting a target polynucleotide. The probe contains a region that base-pairs with a target polynucleotide to form a duplex and a RNA hairpin extension domain... |
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US20070003940 |
Nucleic acid probes for analysis of small RNAs and other polynucleotides
The invention provides a nucleic acid probe for detecting a polynucleotide. The probe contains a region that base-pairs with a polynucleotide to form a duplex and a Tm enhancement domain that... |
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US20060160087 |
Monitoring and treatment of amyotrophic lateral sclerosis
The invention provides methods of monitoring amyotrophic lateral sclerosis (ALS) disease development or progression and monitoring an ALS therapy in an individual by determining the presence or... |
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US20080038192 |
Diagnostic Methods Of Multiple Organ Amyloidosis
Described are methods of assessing whether a subject has or is at risk of having multiple organ amyloidosis (MOA) The method includes detecting a diagnostically predictive collection of biomarkers... |
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US20100221712 |
CELL-MEDIATED IMMUNE RESPONSE ASSAY AND KITS THEREFOR
The present invention provides methods and kits for measuring a cell-mediated immune (CMI) in a small volume of whole undiluted blood collected from a subject. In particular, the methods are for... |
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US20100159465 |
Screening of Abundantly Secreted Proteins and Their Use as Fusion Partners for the Production of Recombinant Proteins
The present invention relates techniques for identifying suitable secretion fusion partner (SFP) for hyper-secretory production of recombinant proteins. The SFPs can be obtained from secretome... |
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US20080317738 |
Mylks as Modifiers of Branching Morphogenesis and Methods of Use
Human MYLK genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for... |
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US20080213247 |
Mbms as Modifiers of Branching Morphogenesis and Methods of Use
Human MBM genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for... |
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US20070003927 |
Mapk7 as modifier of branching morphogenesis and methods of use
Human MAPK7 genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for... |
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US20060257870 |
Cdkl 1 as modifier of branching morphogenesis and methods of use
Human CDKL1 genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for... |
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US20100242134 |
METHODS AND POLYNUCLEOTIDES FOR IMPROVING PLANTS
The invention provides methods for producing a plant with altered tillering time, the methods comprising transformation of a plant with a genetic construct including a polynucleotide encoding of a... |
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US20050064422 |
Polypeptide quantitation
The invention relates to methods and materials useful for determining the actual amount of a selected polypeptide in a sample, by measuring the amount of a cleavage product released from the... |
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US20100037350 |
PLANTS WITH INCREASED YIELD
This invention relates generally to plant cells and/or plants with increased yield as compared to a corresponding non-transformed wild type plant cell by increasing or generating one or more... |
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US20110008376 |
IMMUNOGENIC COMPOSITIONS CAPABLE OF ACTIVATING T-CELLS
The invention provides means and methods for producing and/or selecting immunogenic compositions capable of activating a T-cell and/or a T-cell response, comprising providing said composition with... |
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US20080132417 |
Molecular Basis For The Identification Of Chemotherapy Resistance In Human Tumors And The Treatment Thereof
Provided are compositions and methods for determining whether a tumor in a subject is sensitive or resistant to a chemotherapeutic agent. Further provided are methods and compositions for... |
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US20070072178 |
Novel genetic markers for leukemias
The present invention is related to methods for detecting leukemia cells by determining the expression profile of a group of markers. In particular, the type or subtype of leukemia cells in a... |
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US20090068662 |
METHOD AND TEST KIT FOR THE SEPARATION, PURIFICATION AND RECYCLING OF LONG- AND SHORT-CHAIN NUCLEIC ACIDS
Long- and/or short-chain nucleic acids are separated, purified and recovered by binding the nucleic acid to a solid phase using a binding buffer, to obtain a bonded nucleic acid, and eluting of... |
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US20070037249 |
Molecules that block viral infectivity and methods of use thereof
Embodiments relate to the discovery that certain tripeptide amides and glycine amide can be used to inhibit viral infection, including human immunodeficiency virus (HIV) infection. More... |
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US20050181390 |
Methods of detecting Charcot-Marie Tooth disease type 2A
Methods are described for screening a subject for risk of Charcot-Marie-Tooth Disease Type 2A or for diagnosing Charcot-Marie-Tooth disease or a predisposition for developing Charcot-Marie-Tooth... |
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US20080172763 |
Nod-Factor Perception
The present invention provides a Nod-factor binding element, comprising one or more NFR polypeptides encoded by NFR genes, that are useful for providing non-nodulating plants with Nod-factor... |
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US20060141470 |
Chlamydia pneumoniae associated chronic intraocular disorders and treatment thereof
Infection by Chlamydia pneumoniae has been identified as a risk factor associated with the pathogenesis of certain chronic intraocular disorders, for example, age-related macular degeneration. The... |
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US20070160628 |
Stabilized virus-like particles and epitope display systems
A chimeric polypeptide is disclosed that comprises: i) a first portion that self-assembles into an organized, repetitive, supramolecular structure that contains at least about 9 subunits,... |
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US20070048737 |
Calcium phosphate ceramics and particles for in vivo and in vitro transfection
The invention relates to a method of modifying the surface of calcium phosphate ceramics and powders. The inventive method involves maturation in a culture medium, thereby causing epitaxial... |
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US20060019301 |
Methods of producing mutant polynucleotides
The present invention relates to methods of producing mutants of a polynucleotide and to mutant polynucleotides and artificial variants encoded by the mutant polynucleotides. |
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US20080200408 |
Deletion mutants of tetrodotoxin-resistant sodium channel alpha subunit
The present invention is directed to deletion mutants of a human sodium channel alpha subunit and methods and compositions for making and using the same. |
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US20080299579 |
NOVEL CANCER MARKER AND USE THEREOF
This invention provides a method for cancer diagnosis comprising measuring an endogenous antisense RNA whose relative expression to a sense RNA changes cancer-specifically in RNA-containing... |
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US20070065833 |
Method of detecting thyroid cancer
A method of detecting thyroid cancer in a subject includes obtaining a nucleic acid sample from a bodily sample of the subject and determining whether the nucleic acid sample contains at least one... |
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US20100197518 |
Methods for Diagnosing Ischemia
This invention provides methods and compositions for diagnosing ischemia, ischemia reference expression profiles, and methods for identifying compounds for treating or preventing ischemia. |
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US20100261182 |
PPM1E PROTEINS AND NUCLEIC ACIDS AS TARGETS FOR NEURODEGENERATIVE DISEASES
1. Use of (v) a gene coding for a protein phosphatase 1 E having SEQ ID NO:1 or SEQ ID NO:2, and/or(vi) a transcription product of the gene coding for a protein phosphatase 1 E having SEQ ID NO:1... |
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US20100113379 |
cAMP DEPENDENT INDUCTION OF AUTOPHAGY
The present invention relates to the induction of autophagy via mTOR independent pathways which modulated intracytosolic cAMP levels. In some embodiments, autophagy may be induced in a cell by... |
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US20070122802 |
Methods of diagnosing and treating diabetes and insulin resistance
The present invention provides compositions and methods for diagnosing and treating diabetes and insulin resistance. In particular, the invention provides methods of identifying modulators of the... |
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US20100113299 |
GENE AND GENE EXPRESSED PROTEIN TARGETS DEPICTING BIOMARKER PATTERNS AND SIGNATURE SETS BY TUMOR TYPE
Provided herein are methods and systems for identifying a therapeutic for an individual, such as a therapeutic not previously identified for treating the individual. The therapeutic can be... |
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US20060194212 |
Treatment of AIDS
The invention includes methods of treating HIV infection in a patient where the method includes administration of an antibody to TNF-alpha and an antibody to interferon-gamma to the patient and... |
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US20110059094 |
ANTITUMOR EFFECTS OF INSULIN-RESPONSIVE DNA BINDING PROTEIN-1 (IRDBP-1)
Methods of inhibiting growth of tumor cells with a nucleic acid encoding IRDBP-1 or the carboxyl segment thereof are disclosed. Also disclosed are methods for treating tumor with an antibody... |
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US20060127893 |
Modification of human variable domains
The present invention relates to a method for the optimization of isolated human immunoglobulin variable heavy (VH) and light (VL) constructs. |
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US20070015167 |
Method for detecting vesicoureteral reflux or interstitial cystitis
This invention provides a novel marker of vesicoureteral reflux or interstitial cystitis and a simple and non-invasive method for detecting vesicoureteral reflux or interstitial cystitis. This... |
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US20070134719 |
Method of controlling pharmacokinetics of immunomodulatory compounds
The present invention relates to a method of administering a-interferon into the intradermal compartment of a subject's skin, whereby absorption in the dermis produces improved systemic... |
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US20100004168 |
Use of Crystallin For The Modulation of Angiogenesis
The present invention features therapeutic and prophylactic compositions and methods for modulating a blood vessel by altering angiogenesis, vasculogenesis, blood vessel stabilization, regression,... |
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US20050019772 |
Method for detecting bacteria associated with parodontitis and tooth decay
The invention relates to the diagnosis of microorganisms, especially the detection of microorganisms which are associated with the disease known as parodontitis or tooth decay. The information... |
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US20070092889 |
Parkinson's disease-related disease compositions and methods
Compositions and methods for use in the therapeutic and preventative treatment, study, diagnosis and prognosis of PD-related disease are disclosed. Also provided are kits and reagents for... |
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US20090070892 |
PROMOTER, PROMOTER CONTROL ELEMENTS AND COMBINATIONS AND USES THEREOF
The present invention is directed to nitrogen responsive promoter sequences and promoter control elements, polynucleotide constructs comprising the nitrogen responsive promoters and control... |
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US20070020629 |
Devices for component removal during blood collection, and uses thereof
The invention relates to a device and method for collecting blood whereby certain target components are isolated or removed from the blood sample at the time of collecting the blood, as well as... |
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US20110021466 |
USE OF EPICATECHIN AND DERIVATIVES AND SALTS THEREOF FOR CARDIAC PROTECTION OF ISCHEMIC MYOCARDIUM AND TO AMELIORATE ADVERSE CARDIAC REMODELING
The disclosure provides a method of reducing infarct size in the heart following permanent ischemia or ischemia/reperfusion (IR) event or method for delaying, attenuating or preventing adverse... |