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US20100190174 |
ADAM12, A NOVEL MARKER FOR ABNORMAL CELL FUNCTION
The present invention provides a method, an assay and a kit for providing an indication of abnormal cell function. It was surprisingly found that the change in the serum ADAM12 concentration in... |
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US20090148843 |
Means and Methods for the Prediction of Joint Destruction
The present invention relates to a method of diagnosing and/or predicting joint destruction, early joint destruction and/or accelerated joint destruction in particular, in rheumatoid arthritis,... |
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US20100086501 |
Determining Age Ranges of Skin Samples
The present invention provides methods for characterizing a skin sample of a subject as belonging to an age range by analyzing nucleic acid or protein molecules obtained from the subject. The... |
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US20080305118 |
Treatment Of Type 1 Diabetes With Inhibitors Of Macrophage Migration Inhibitory Factor
Methods of treating a mammal having type 1 diabetes or a risk for type 1 diabetes are provided. The methods comprise administering to the mammal a pharmaceutical composition comprising an agent... |
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US20090047215 |
MN/CA IX and Breast Cancer Therapy
Herein disclosed are methods that are predictive of resistance to endocrine therapy in an estrogen receptor-positive (ER-positive) breast cancer patient. An exemplary method comprises detecting... |
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US20060015954 |
GPR54 knock-out mammals and screening methods using them
The present invention relates to novel functions of a known receptor. In particular, the invention relates to the use of a galanin-like receptor and/or ligands thereof in the manipulation of the... |
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US20050069885 |
Modulating urea degradation in wine yeast
The invention provides yeast strains transformed to reduce nitrogen catabolite repression of a gene encoding a urea degrading enzymatic activity expressed by the yeast strain under fermenting... |
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US20050100901 |
Vaccine for treating nicotine addiction
The present invention provides active or passive forms of immunotherapy against the metabolites of nicotine. For example, there is provided a vaccine comprising a metabolite of nicotine, and in... |
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US20050112626 |
Making and using microclonal uncloned cDNA libraries
A method is described for the preparation, characterization and utilization of temporally ordered panels of cDNA libraries from human microclones. Each microclone undergoing morphogenetic... |
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US20090013431 |
Stress tolerant cotton plants
The invention relates to the use of cotton parp2 gene or cDNA sequences to obtain stress tolerant cotton plants. Various cotton parp2 sequences are also provided. |
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US20060088821 |
Construction and use of catalogued nucleic acid libraries that contain advantageously adjusted representations of defined components
A process for constructing a catalogued nucleic acid library in which the proportional representation of the constituents is adjusted to advantage through the use of disclosed technologies for... |
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US20060141473 |
Erk7 and erk8, novel diagnostic markers for cancer
The present invention is directed in part to the discovery of a novel signal transduction pathway that regulates estrogen responsiveness. Human extracellular signal-regulated kinase 8 (ERK8) has... |
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US20070031450 |
Stabilizers for veterinary vaccines
A formulation for a animal vaccines is provided. The vaccine formulation contains a stabilizer component and a viral immunogen. The stabilizer component includes a substantially TSE/BSE-safe... |
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US20070224622 |
Plant chimeric binding polypeptides for universal molecular recognition
Libraries of nucleic acids encoding chimeric binding polypeptides based on plant scaffold polypeptide sequences. Also described are methods for generating the libraries. |
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US20060078919 |
Diagnostic test kit and methods of diagnosis and treatment of helicobacter SPP. associated infections
The present diagnostic test kit and methods of diagnosis and treatment of Helicobacter spp. associated infections provides accurate diagnosis and treatment for Helicobacter spp. related infections... |
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US20100216129 |
GENETIC LOCI ASSOCIATED WITH FUSARIUM SOLANI TOLERANCE IN SOYBEAN
The invention relates to methods and compositions for identifying soybean plants that are tolerant, have improved tolerance or are susceptible to Fusarium solani infection (the causative agent of... |
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US20050043227 |
Use of hypoxia inducible factor 2alpha for curing neonatal respiratory distress syndrome and as a target for the treatment of pulmonary hypertension
The current invention relates to the field of hypoxia-induced disorders and more specifically to the use of hypoxia inducible factor 2aα as a target in a method for the screening for molecules... |
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US20100159457 |
SYSTEM AND METHOD FOR PRESENTING DNA BINDING SPECIFICITIES USING SPECIFICITY LANDSCAPES
A system and method for analyzing DNA binding specificities is provided. The potential binding motifs are compared to a plurality of DNA sequences. The DNA sequences are plotted within a... |
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US20050079502 |
Transplant rejection suppressor
The present invention relates to a transplant rejection suppressor, as well as foods, drinks, nutriments and pharmaceuticals containing the same. Further, the present application relates to a... |
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US20090081662 |
Homogeneous Luminescence Bioassay
This invention relates to a homogenous bioassay for use in measurement of biological activity, its modulation or analyte concentration of a sample, said bioassay comprising a first group... |
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US20090156467 |
Thymic stromal lymphpoietin promoter and use therefor
A promoter comprising the isolated promoter region of the human Thymic Stromal Lymphopoietin (TSLP) gene and functional portions of the promoter region having TSLP promoter activity. The promoters... |
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US20100267040 |
MN/CA IX and Cancer Prognosis
Herein disclosed are methods that are prognostic for neoplastic/preneoplastic disease in a subject vertebrate, wherein said disease is associated with a tissue that normally expresses MN, but... |
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US20100168231 |
TARGET ENZYME FOR THE TREATMENT OF ACNE
The use of an enzyme as a research tool for acne, by identifying a compound for the treatment of acne and/or any disorder associated with cutaneous hyperseborrhoea. |
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US20090123931 |
IDENTIFICATION OF TISSUE FOR DEBRIDEMENT
Provided are methods of determining whether a cell in a tissue site is viable or nonviable. Also provided are methods of debriding tissue from a tissue site. Further provided are kits comprising a... |
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US20090226420 |
Methods of Determining the Risk of Developing Coronary Artery Disease
The invention relates to predicting, or aiding in predicting, which individuals are at risk of developing coronary artery disease. The invention provides a method for identifying an individual who... |
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US20050053932 |
Novel stress-associated genetic products from ashbya gossypii
The present invention relates to novel polynucleotides from Ashbya gossypii; to oligonucleotides hybridizing therewith; to expression cassettes and vectors which comprise these polynucleotides; to... |
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US20080317733 |
Cosmeceutical Compositions and Methods with Biologically Active Ingredients
Cosmeceutical formulations are personalized to address an individual's nutrient deficiencies and genetic predispositions for premature aging of the skin. Growth factors and high doses of... |
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US20100221735 |
DIAGNOSTIC TEST FOR PARKINSON'S DISEASE
The present invention relates to molecular markers for detection, prognosis and follow up of Parkinson's disease (PD), wherein said molecular markers are one or more genes with altered expression... |
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US20060292553 |
Method for study of the genetic and functional variability of HIV and kit for using it
A method of analyzing a sample possibly containing an HIV virus, including a) extracting viral RNA in a biological sample that possibly contains an HIV virus; b) reverse transcription of the RNA... |
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US20100203526 |
MECP2E1 gene
The invention is a novel MECP2E1 splice variant and its corresponding polypeptide. The invention also includes methods of using these nucleic acid sequences and proteins in medical diagnosis and... |
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US20110059443 |
FLUORESCENT GFP VARIANT DISPLAYING HIGHLY INCREASED FLUORESCENCE INTENSITY WITHOUT A SPECTRAL SHIFT
The present invention relates to a nucleic acid molecule encoding a polypeptide having a fluorescence emission activity with a maximum emission at 505 to 515 nm, wherein said nucleic acid molecule... |
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US20060003311 |
In vitro screening of cellular events using 3d cell culture systems
The present invention relates to in vitro cell culture conditions wherein transfected cells containing promoter-reporter constructs are cultivated in a 3D tissue-like environment. The referred 3D... |
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US20080159999 |
Compositions and methods for identifying, isolating and enriching germline-like stem cells from amniotic fluid
The present invention is directed to pluripotent embryonic stem cells derived from amniotic fluid and the methods for isolating, expanding and differentiating these cells, and their therapeutic... |
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US20070059751 |
Nucleic acid isolation method
In a nucleic acid isolation method for a solid biological sample, since two or more kinds of instruments are used for biological sample disruption and nucleic acid isolation, the operations are... |
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US20100266548 |
LPS-Responsive CHS1/Beige-Like Anchor Gene and Therapeutic Applications Thereof
The present invention relates to a novel LPS-responsive and Beige-like Anchor gene (lrba), variants of the lrba gene, fragments of the lrba gene, and polypeptides encoded thereby. The subject... |
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US20070259825 |
Transgenic Mammals and Cell Lines for the Identification of Glutamate Transporter Modulators
The invention includes a transgenic, non-human mammal useful for identifying candidate compounds for treating neurological and/or psychiatric disorders. Incorporated into the genome of the... |
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US20080293072 |
METHOD FOR ENUMERATION OF MAMMALIAN MICRONUCLEATED ERYTHROCYTE POPULATIONS, WHILE DISTINGUISHING PLATELETS AND/OR PLATELET-ASSOCIATED AGGREGATES
A method for the enumeration of micronucleated erythrocyte populations while distinguishing platelet and platelet-associated aggregates involves the use of a first fluorescent labeled antibody... |
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US20050227275 |
Nucleic acid detection system
The present application discloses a system for detecting target nucleic acid comprising: a container comprising a nucleic acid amplification mix comprising a primer labeled with different haptens... |
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US20100249210 |
METHODS AND COMPOSITIONS RELATED TO DLK-1 AND THE P38 MAPK PATHWAY IN NERVE REGENERATION
Disclosed are compositions and methods for treating neurodegenerative disease. |
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US20060160085 |
Novel buffer formulations for isolating purifying and recovering long-chain and short-chain nucleic acids
The invention relates to novel formulations of buffers used for isolating, purifying and recovering long-chain and short-chain nucleic acids. The areas of application of the inventive method... |
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US20070031835 |
Diagnosis of advanced cancer
The present invention relates generally to a method of diagnosing, predicting or monitoring the development or progress of advanced cancer and, in particular, to a method of diagnosing, predicting... |
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US20090233840 |
Modified Dynorphin Expression in Animals and Identification of Compounds for Treatment of Obesity and Diabetes
The present invention provides novel transgenic animal models of reduced dynorphin expression in humans that are useful for identifying compounds that are antagonists, inverse agonists, agonists... |
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US20090215064 |
QUANTITATIVE ASSESSMENT OF INDIVIDUAL CANCER SUSCEPTIBILITY BY MEASURING DNA DAMAGE-INDUCED MRNA IN WHOLE BLOOD
Heparinized human whole blood from patients with invasive breast cancer, with (multiple primary) and without (single primary) a second primary cancer, and from unaffected controls was stimulated... |
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US20070122825 |
Method to predict the response to lithium treatment
The disclosure provides methods and compositions useful for identifying a subject's predisposition to lithium treatment. |
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US20100003679 |
ASSESSMENT OF CELLULAR COMPOSITION AND FRACTIONAL VIABILITY AND USES THEREOF
A method of assessing cellular composition and fractional viability that can be predictive of post-transplant cell potency and transplantation outcome, comprises identifying cellular composition... |
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US20070270504 |
Identification of Therapeutic Agents Using Genetic Fingerprinting
Methods for identifying compounds having similar biological activity based on similarity in genetic expression profile in cells contacted with one or more of said compounds, along with... |
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US20050048550 |
EphA2 T-cell epitope agonists and uses therefor
EphA2 T-cell epitope agonists are provided herein. The agonists include peptides corresponding to specific fragments of human EphA2 protein containing one or more T-cell epitopes, and conservative... |
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US20090312251 |
Methods of regulating differentiation in mammals
Mechanisms regulating cell proliferation stop and differentiation initiation during the development stage of mammalian embryo, and the proteins involved therein, are presented. Differentiation... |
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US20090053701 |
Detectable nucleic acid tag
Provided herein are nucleic acid tags that are linked to, or capable of linking to, a protein of interest. In particular, the nucleic acid tags are oligonucleotides comprising a reporter function... |
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US20060014165 |
Methods of diagnosis and treatment for asthma and other respiratory diseases based on haplotype association
Methods for diagnosis of asthma or a susceptibility to asthma based on detection of at-risk haplotypes associated with MAP3K9 are disclosed. Also methods for treatment of asthma or a... |