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US20090220971 |
Treatment Response in Generalized Social Phobia
This invention generally pertains to the field of psychiatry. In particular, this invention relates to, inter alia, the discovery that a subject's serotonin transporter gene promoter polymorphism... |
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US20070238095 |
Detection of Influenza A Virus
The invention provides methods to detect influenza A in biological samples using real-time PCR. Primers and probes for the detection of influenza A are provided by the invention. Articles of... |
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US20080124718 |
METHODS OF DIAGNOSING, PREDICTING THERAPEUTIC EFFICACY AND SCREENING FOR NEW THERAPEUTIC AGENTS FOR LEUKEMIA
The invention discloses methods for leukemia diagnosis and determining the effectiveness of certain therapies. The methods of the present invention also encompass a way to predict a subject's... |
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US20080038727 |
MicroRNA and Messenger RNA Detection on Arrays
The present teachings provide methods for reverse transcribing, and detecting, a plurality of small nucleic acids such as micro RNAs, from the same reaction mixture as a plurality of messenger... |
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US20090170712 |
Using Oligonucleotide Microarrays to Analyze Genomic Differences for the Prediction of Heterosis
A novel method for prediction of the degree of heterotic phenotypes in plants is disclosed. Structural variation analyses of the genome are used to predict the degree of a heterotic phenotype in... |
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US20100311054 |
Compositions and Methods for the Detection of Human T Cell Receptor Variable Family Gene Expression
Compositions and methods for the assessment of T cell receptor variable subunits. The present invention provides nucleotide sequences for the evaluation of the expression of TCRV families. These... |
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US20100028869 |
METHOD TO ASSESS SUSCEPTIBILITY TO ANDROGENIC ALOPECIA
The present invention relates to a method to assess the susceptibility to androgenetic alopecia comprising detecting the presence of polymorphisms in the EDA2R gene. |
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US20070218459 |
Diagnostic System For Otolaryngologic Pathogens And Use Thereof
The present invention relates to a method of detecting the presence of an otolaryngologic pathogen in a biological sample, and a sensor device, sensor chip, and nucleic acid probes useful for... |
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US20060014191 |
Analog probe complexes
The present invention relates to the detection of target sequences. The present description discloses compositions and methods involving analog nucleic acids, such as PNA and L-DNA, for the... |
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US20100266680 |
Treatment of Cancer Using TLR3 Agonists
The present invention relates generally to the fields of genetics and medicine. More specifically, the present invention relates to improved methods of treating cancers using a TLR3 agonist, by... |
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US20100330557 |
GENOMIC COORDINATE SYSTEM
A method of sample analysis is provided. In certain embodiments, the method comprises: a) site-specifically labeling a test genome with at least two different labels to produce a labeled genome... |
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US20100215641 |
SCREENING METHOD FOR COMPOUNDS THAT REDUCE ER STRESS
The present invention relates to a cell comprising an Endoplasmic Reticulum (ER) stress element operably linked to a reporter element and an exogenous gene encoding a protein that induces ER... |
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US20100017909 |
Nitrate transport components
This invention relates to isolated nucleic acid fragments encoding high affinity nitrate transport components. The invention also relates to the construction of recombinant DNA constructs encoding... |
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US20070231304 |
PROGNOSTIC FACTORS FOR ANTI-HYPERPROLIFERATIVE DISEASE GENE THERAPY
The present invention relates to the identification of various prognostic factors that predict response in patients with hyperproliferative disease such as cancer to gene therapy, and their use in... |
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US20090280486 |
Oligonucleotides for Detecting Nucleic Acids of Pathogen Causing Sexually Transmitted Diseases
The present invention relates to oligonucleotides hybridizable with nucleic acids of pathogens causing sexually transmitted diseases, kits comprising them, and processes for amplifying and... |
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US20070254288 |
Diagnostic methods for pain sensitivity and chronicity and for tetrahydrobiopterin-related disorders
Disclosed herein are methods for determining whether a subject possesses altered pain sensitivity an altered risk of developing acute or chronic pain, or diagnosing a tetrahydrobiopterin... |
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US20100081648 |
Methods for Characterizing and Treating Cognitive Impairment In Aging and Disease
This invention provides methods for identifying genes associated with cognitive impairment and for identifying compounds useful in the treatment of cognitive impairment. The methods can in... |
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US20090258789 |
METHODS OF DETERMINING THE PROGNOSIS OF AN ADENOCARCINOMA
Methods are disclosed for determining the prognosis of a subject with an adenocarcinoma in an organ, such as the lung. The methods can include quantitating expression of a plurality of cytokines... |
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US20090298061 |
Diagnostic Methods for the Prediction of Therapeutic Success, Recurrence Free and Overall Survival in Cancer Therapy
Described are 12 human genes which are differentially expressed in neoplastic tissues of patients responding well to treatment as compared to patients not responding well as determined by overall... |
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US20100136553 |
Prognosis prediction for melanoma cancer
The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically,... |
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US20050202416 |
Mouse hepatitis virus detection
The present invention relates to the identification of a nucleotide sequence that is conserved in the genome of the Mouse Hepatitis Virus (MHV) and to the design and construction of synthetic... |
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US20060008450 |
Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure
The invention provides isolated stem cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple tissue types. Also... |
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US20070003937 |
Increasing hybridization efficiencies
Aspects of the disclosure are generally directed to probes and probe compositions for detecting or quantifying a target. One aspect provides a method for selectively hybridizing a probe to a... |
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US20090105184 |
POSITRON EMISSION TOMOGRAPHY PROBES FOR IMAGING IMMUNE ACTIVATION AND SELECTED CANCERS
Compounds for use as PET probes and methods for synthesizing and using these, comprising [18F]D-FAC and other cytosine and adenosine analogs. |
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US20070015187 |
METHODS FOR RNA PROFILING
The present teachings provide methods, compositions, and kits for detecting micro RNAs (miRNAs). In some embodiments, the miRNAs are quantified from formalin-fixed paraffin-embedded tissue samples... |
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US20080305474 |
Method and Apparatus for Using SLC2A10 Genetic Polymorphisms for Determining Peripheral Vascular Disease in Patients with Type-2 Diabetes
Recent data indicate that a loss-of-function mutation of the SLC2A10 gene causes arterial tortuosity syndrome (ATS) via upregulation of the TGF-β pathway in the arterial wall, a mechanism possibly... |
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US20100179310 |
GENETIC ANALYSIS OF CELLS
Some aspects relate to methods for genetic analysis of selected cells from within a heterogeneous population of cells. The population of cells first can be partitioned. Selected cells are... |
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US20090170079 |
Regulation of RUNX1 for Treatment of Pain
Methods are provides for identifying candidate agents for use in inhibiting expression of certain receptors and ion channels in nociceptors. Also provided are methods for identifying candidates... |
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US20090029368 |
Method for determining the cell culture history of a cell unit labelled with more than one type of tag
The present invention relates in one aspect to a method for determining the cell culture history of a cell unit labelled with more than one type of tag comprising the steps of: (a) measuring one... |
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US20100196887 |
COMPOSITIONS AND METHODS FOR MULTIPLEX ANALYSIS OF POLYNUCLEOTIDES
Provided herein are compositions and methods for the multiplex analysis and/or detection of polynucleotides having one or more distinguishable target sequences. The methods employ signal-quencher... |
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US20090098141 |
IL-1 gene cluster, insulin resistance and coronary artery disease associated polymorphisms and haplotypes and methods of using same
The invention provides methods and compositions relating to identification and use of genetic information from the IL-1 gene cluster—including the structure and organization of novel IL-1-like... |
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US20100281555 |
METHOD FOR MARKING BIO-INFORMATION INTO GENOME OF ORGANISM AND ORGANISM MARKED WITH THE BIO-INFORMATION
Disclosed herein is a method for marking bio-information into the genome of an organism, an organism marked with inherent bio-information by the method and a method for reading the... |
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US20100167305 |
Methods of Detecting Mutations Associated With Ataxia-Ocular Apraxia 2 (AOA2)
Methods of identifying polymorphisms associated with ataxia-ocular apraxia 2 (AOA2), are described. The polymorphisms associated with AOA2 include specific mutations in the senataxin (SETX) gene.... |
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US20060218669 |
Sialylation of glycoproteins in plants
The presence of sialic acids (SAs) at the non-reducing terminal of various glycoconjugates plays important roles in the function and half-life of glycoproteins in mammals and many species of... |
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US20090012371 |
GENETIC MARKERS OF SCHIZOPHRENIA
The invention includes method of determining if a subject has a genetic predisposition to clinically diagnosed schizophrenia (SZ), schizotypal personality disorder (SPD), and/or schizoaffective... |
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US20100291569 |
ASSAY FOR PREDICTION OF RESPONSE TO MET ANTAGONISTS
A method for classifying cancer patients as likely to have lower response to MET receptor antagonist therapy comprises assessment of the presence or absence of a single nucleotide polymorphism in... |
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US20090208952 |
UTILITY OF RET MUTANT IN DIAGNOSIS AND TREATMENT OF MELANOMA
The invention relates to a method of detecting a RET mutant in a melanoma cell. Also disclosed is a method of modulating the activity of a RET mutant in a melanoma cell with an agent that... |
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US20080299540 |
Hormone responsive tissue culture system and uses thereof
The invention provides tissue culture system for primary cells (e.g. normal mammalian primary epithelial progenitors). This system includes: a) a serum-free, chemically defined cell culture media;... |
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US20080318217 |
Identification of Gene Associated with Reading Disability and Uses Therefor
The present invention relates to identification of a human gene, DCDC2 (MIM: 605755), associated with susceptibility for developing reading disability (RD), which is useful in identifying or... |
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US20100216713 |
NOVEL COMPOSITIONS AND METHODS IN CANCER ASSOCIATED WITH ALTERED EXPRESSION OF PRLR
The present invention relates to novel sequences for use in diagnosis and treatment of carcinomas, especially breast cancers. In addition, the present invention describes the use of novel... |
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US20050042614 |
Methods to treat diabetes and related conditions based on polymorphisms in the tcf-1 gene
This invention relates to the use of the novel association between the 483 A>G single nucleotide polymorphism of the TCF1 gene and the clinical response to glycemic control agents, such as DPPIV... |
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US20080182249 |
Expression systems for mammalian and mycobacterial desaturases
Expression system for components of a desaturase complex is provided. The system includes expression of a desaturase and an oxidoreductase. The system may be used for expression of mycobacterial... |
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US20090111877 |
Methods for Enhancing the Quality of Life of a Senior Animal
Methods for enhancing the quality of life of a senior or super senior animal by feeding the animal a composition comprising at least one omega-3 polyunsaturated fatty acid and various combinations... |
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US20090023151 |
Method For The Labeling And Detection Of Small Polynucleotides
Methods and kits for use in isolating, labeling or detecting a small polynucleotide of interest from a sample. The method entails hybridizing the small polynucleotide to a capture probe,... |
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US20100190179 |
Lateral Flow Methods and Devices for Detection of Nucleic Acid Binding Proteins
Methods and devices are provided for detecting the presence or absence of nucleic acid binding proteins, such as NMP22, and other proteins, in bodily fluids. |
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US20100279296 |
ENHANCED FC RECEPTOR-MEDIATED TUMOR NECROSIS FACTOR SUPERFAMILY MRNA EXPRESSION IN PERIPHERAL BLOOD LEUKOCYTES IN PATIENTS WITH RHEUMATOID ARTHRITIS
A method for predicting patient responsiveness to rheumatoid arthritis treatments involving altering expression of tumor necrosis factor superfamily (“TNFSF”)-2, TNFSF-8, or TNFSF-15 is disclosed.... |
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US20050118584 |
Detection board
There are provided a) a detection board having numerous wells on a surface thereof, b) a detection set including the detection board and an element serving as well sealing means, and c) a method... |
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US20070059687 |
Process for evaluating phagocytotic function and use thereof
A digested phagocyte prepared by contacting in vitro a phagocyte with a foreign microorganism and isolating the phagocyte so contacted; a process for producing the same; and a process and a kit in... |
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US20070092875 |
Map2k6 as modifier of branching morphogenesis and methods of use
Human MAP2K6 genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for... |
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US20100080780 |
PLURIPOTENT AUTOLOGOUS STEM CELLS FROM ORAL MUCOSA AND METHODS OF USE
The present invention provides a new readily accessible source of adult somatic stem cells from the gastrointestinal tract in general and oral mucosa in particular, methods for isolating... |