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US20070207486 |
ANGIOGENESIS PATHWAY GENE POLYMORPHISMS FOR THERAPY SELECTION
A method for determining whether a patient in need thereof will respond to anti-VEGF antibody based chemotherapy by screening a suitable cell or tissue sample isolated from the patient for at... |
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US20060084090 |
Modulation of interaction between Nod1 and Gram-negative bacteria by Nod1 response to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island (cagPAI)
A method for identifying a compound that modulates the interaction between Nod1 and a Gram-negative bacteria comprising contacting a Nod1 expressing cell with a cagPAI-positive H. pylori in the... |
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US20100203522 |
METHOD TO PREDICT OR DIAGNOSE A GASTROINTESTINAL DISORDER OR DISEASE
The disclosure provides methods and compositions useful for identifying a subject's predisposition to a gastrointestinal disease or disorder. |
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US20050176039 |
Macrophage migration inhibitory factor (MIF) as marker for urological inflammatory disease
The present invention relates to the association between detecting and quantifying the presence of macrophage migration inhibitory factor (MIF) in urine, bladder and prostate tissues for the... |
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US20060246464 |
Method of isolating, labeling and profiling small RNAs
Disclosed herein is a method of selectively labeling non-messenger RNA molecules by isolating total RNA from a tissue or cell, dissolving the isolated RNA, blocking the 3′ end of the RNA and... |
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US20090030082 |
SYNTHETIC LIGANDS SELECTIVE FOR LXRbeta OVER LXRalpha, IDENTIFICATION AND METHODS OF USE THEREOF
LXR nuclear receptor agonists have been previously shown to increase cholesterol efflux, raise plasma HDL cholesterol, stimulate cholesterol excretion, and reduce atherosclerotic lesions. However,... |
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US20050176945 |
Cloning and characterization of slc26a7 and slc26a9 anion exchangers
Isolated nucleic acids encoding SLC26A7 and SLC26A9 anion transporter polypeptides, recombinantly expressed SLC26A7 and SLC26A9 anion transporter polypeptides, heterologous expression systems for... |
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US20100279298 |
Methods and Compositions For Detecting Autoimmune Disorders
The invention provides methods and compositions useful for detecting autoimmune disorders. |
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US20100267033 |
Methods and Compositions For Detecting Autoimmune Disorders
The invention provides methods and compositions useful for detecting autoimmune disorders. |
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US20090203006 |
BIOLOGICAL MARKERS OF CHRONIC WOUND TISSUE AND METHODS OF USING FOR CRITERIA IN SURGICAL DEBRIDEMENT
The present invention relates to methods for identifying tissue sites in a chronic wound that are suitable for debridement and whether debridement procedure has been successful using particular... |
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US20080025997 |
Cysteine-rich region of respiratory syncytial virus and methods of use therefor
The invention features methods and compositions featuring an RSV Glycoprotein fragment for modulating an immune response in a subject. |
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US20080014586 |
IDENTIFICATION OF A RECEPTOR CONTROLLING MIGRATION AND METASTASIS OF SKIN CANCER CELLS
The invention relates generally to genes expressed in skin cancer cells, particularly melanoma tumor cells, and their role in migration and metastasis. Methods for identifying melanoma cells are... |
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US20070259367 |
METHOD TO DIAGNOSE AND INCREASE FERTILITY OF MAMMALIAN SEMEN USING DNASE AS A DIAGNOSTIC MARKER AND THERAPEUTIC AGENT
A method and a corresponding composition of matter for diagnosing or increasing the fertility of semen is described. The method involves measuring DNase activity in a semen sample, wherein greater... |
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US20100151470 |
METHODS AND COMPOSITIONS FOR LOCATING SNP HETEROZYGOSITY FOR ALLELE SPECIFIC DIAGNOSIS AND THERAPY
The present invention provides methods for the rapid and cost effective identification of the presence of a disease-associated mutation and a particular SNP in the same allele of a gene without... |
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US20100041036 |
GENOMIC MORSE CODE
The present invention relates to a method of detection of the presence of at least one domain of interest on a macromolecule to test, wherein said method comprises the following steps: a)... |
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US20100003691 |
Genetic Markers Associated with Degenerative Disc Disease and Uses Thereof
The present invention relates to novel genetic markers associated with degenerative disc disease (DDD), risk of developing DDD and risk of DDD progression, and methods and materials for... |
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US20070141597 |
Biomimetic Biodetector of Toxins, Viruses, Bacteria, and Biological Factors
A method for detecting a target agent in an environment is disclosed. The method includes preparing a biomimetic ligand, the ligand providing a site at which the target agent will bind. The method... |
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US20100255117 |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
The instant invention provides methods and compositions for the treatment of cancer. |
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US20090155796 |
MARKER FOR CANCER PROGNOSIS AND METHODS RELATED THERETO
The present invention is related to the novel discovery that HIF-2α, but not HIF-1α, selectively regulates adenosine A2A receptor in endothelial cells, thereby revealing a unique and hitherto... |
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US20080213751 |
ILCS BASED PATTERN RECOGNITION OF SEPSIS
The present invention refers to a method for recognizing and/or characterizing cellular activity patterns, in particular for diagnostic purposes and/or for tracking the therapy of diseases. Blood... |
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US20060172304 |
Method for modulating epithelial stem cell lineage
The present invention relates to methods of modulating epithelial stem cell lineage by regulating the expression of Lef1 or a BMP inhibitor and/or the stability of β-catenin or the expression of a... |
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US20090081647 |
Detection of a genetic predisposition to cancers and non-cancerous pathologies in mammals
Methods are provided for the detection of susceptibility to cancer and non-cancerous pathologies in a mammal. Diagnostic kits are also provided. |
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US20100248219 |
Compositions for use in identification of influenza viruses
The present invention provides oligonucleotide primers, compositions, and kits containing the same for rapid identification of viruses which are members of the influenza virus family by... |
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US20100173320 |
Methods for Detecting Nucleic Acids Indicative of Cancer
The invention provides methods for screening tissue or body fluid samples for nucleic acid indicia of cancer or precancer. |
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US20060078886 |
Business methods for modulating angiogenesis
The present invention relates business methods comprising the steps of commercializing a tRNA synthetase fragment or a multi-unit complex comprising a tRNA synthetase fragment for modulating an... |
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US20100292339 |
Genetic Polymorphisms Predictive of Nutritional Requirements for Choline in Subjects
Methods of predicting susceptibility of a subject to develop one or more choline deficiency-associated health effects are provided, comprising determining a genotype of the subject with respect to... |
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US20080118913 |
Genetic manipulation of brain serotonin using the pet-1 transcriptional control region
Serotonin neurons modulate most homeostatic Central Nervous System (CNS) functions while influencing the expression of behavioral traits such as mood, aggression and anxiety. Serotonin neuron... |
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US20100092444 |
PLATELET RICH PLASMA FORMULATIONS FOR CARDIAC TREATMENTS
Compositions for platelet rich plasma (PRP) are provided. Generally, these compositions comprise a higher concentration of platelets and white blood cells than whole blood. The concentrations of... |
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US20050032062 |
Methods for the assessment and prognosis of sarcoidosis
This invention identifies genes and the mRNA and polypeptide expression products of these genes which can be used as biomarkers to provide diagnostic and prognostic information in patients with... |
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US20100197767 |
NUCLEIC ACID CONSTRUCT SYSTEMS CAPABLE OF DAIGNOSING OR TREATING A CELL STATE
Nucleic acid construct systems are disclosed capable of diagnosing and treating a cell state (e.g. disease state). Methods of diagnosing and treating disease states using the nucleic acid... |
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US20090214514 |
GUS3 NEUROPEPTIDES FOR REGULATING HYPOTHALAMIC FUNCTION
The present invention relates to use of GUS3 neuropeptides or functional variants in a medicament. The invention furthermore relates to specific medical uses of such neuropeptides, for regulating... |
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US20100021438 |
KIDNEY DERIVED STEM CELLS AND METHODS FOR THEIR ISOLATION, DIFFERENTIATION AND USE
The invention relates generally to methods for isolation and culture of kidney stem cells, cells isolated by the methods, and therapeutic uses for those cells. |
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US20090291432 |
Genetic profiles associated with the 957C>T polymorphism in the DRD2 gene
The present invention relates to a method for profiling an individual or group of individuals with respect to a neurological, psychiatric or psychological condition, phenotype or state, including... |
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US20050013808 |
Nitroreductase enzymes
Improved nitroreductase enzymes, particularly for use as prodrug converting enzymes are provided. In particular, single and double mutants of the E. coli NFSB nitroreductase, having improved... |
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US20100173313 |
BIOMARKERS OF INFLAMMATION
Methods for the detection of DP2 receptors in biological samples is disclosed. The induction and detection of DP2 receptors expressed on activated human neutrophils is presented. Also presented... |
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US20100203512 |
METHOD FOR RENAL DISEASE DIAGNOSIS AND PROGNOSIS USING ANNEXIN A1 AND RAB23 AS MARKERS
Use of Annexin A1 or Rab23 as a biomarker for diagnosing kidney disease or assessing efficacy of kidney disease treatment. |
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US20100041023 |
Inactivated FCV vaccines
The present invention relates to improved inactivated feline calicivirus (FCV) vaccines. The invention also provides a process for producing stabilized inactivated FCV, and the use of such... |
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US20090093424 |
Markers for melanoma
A method of diagnosing melanoma and/or monitoring melanoma progression, in particular for determining whether the melanoma is likely to have metastatic capabilities, in a subject includes the... |
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US20070072222 |
FABP4 as biomarker for toxic effect
The present invention relates to FABP4 as a marker for determining at least one toxic effect of a compound of interest and methods for determining same. |
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US20100183521 |
METHODS OF DETECTING AND TREATING COLON DISORDERS
The subject invention pertains to a method of detecting colon disorders including inflammatory bowel disease, such as Crohn's disease and ulcerative colitis, based on underexpression of... |
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US20080293661 |
METHOD FOR TREATING CHRONIC LYMPHOID LEUKEMIA
Embodiments of the invention relates to the treatment of chronic lymphoid leukemia. The invention provides treatment, diagnostic, and drug discovery strategies for chronic lymphoid leukemia.... |
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US20090298838 |
Method for Determination of Effective Dose of Methotrexate
Problems: Provided are a test method of determining an effective dose of methotrexate in each patient and a method for treatment of rheumatoid arthritis. Means to Solve the Problems: There is... |
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US20110020790 |
USE OF REGULATORY SEQUENCES FOR SPECIFIC, TRANSIENT EXPRESSION IN NEURONAL DETERMINED CELLS
The present invention relates to the use of regulatory sequences for mediating specific, early transient expression in proliferative neuronal determined cells. Furthermore, the uses of recombinant... |
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US20110016547 |
USE OF REGULATORY SEQUENCES FOR SPECIFIC, TRANSIENT EXPRESSION IN NEURONAL DETERMINED CELLS
The present invention relates to the use of regulatory sequences for mediating specific, early transient expression in proliverative neuronal determined cells. Furthermore, the uses of recombinant... |
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US20050095240 |
NaCT as a target for lifespan expansion and weight reduction
The present invention provides the identification and characterization of a novel transmembrane transporter, a Na+-coupled citrate transporter (“NaCT”). Isolated polynucleotides encoding the... |
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US20070172828 |
Genetic algorithms for optimization of genomics-based medical diagnostic tests
In a genetic optimization method, the genes of a chromosome population are computationally genetically evolved. The evolving includes evolving a number of expressed genes in each chromosome and... |
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US20050142561 |
Intracellular signaling pathways in diabetic subjects
The present invention provides for methods of identifying subjects with a predisposition towards, or the existing condition of, type II diabetes. The methods involve examination of at least three... |
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US20100129408 |
KLEBSIELLA PNEUMONIAE ATTENUATED VIRULENCE MUTANT AND METHOD OF PRODUCTION
The present invention relates to a Klebsiella pneumoniae gene-deleted mutant and its producing methods. The main objective of this invention is to construct a Klebsiella pneumoniae tonB deletion... |
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US20090215036 |
Genetic Alterations Useful For The Response Prediction of Malignant Neoplasia to Taxane-Based Medical Treatments
The invention provides novel compositions, methods and uses, for the diagnosis, prognosis, prediction, prevention and aid in treatment of malignant neoplasia such as breast cancer, ovarian cancer,... |
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US20090226914 |
METHODS AND PRODUCTS TO TARGET, CAPTURE AND CHARACTERIZE STEM CELLS
A method for identifying cancer stem cells, comprises reacting a plurality of cells comprising cancer stem cells with an anti-nucleolin agent to bind the anti-nucleolin agent to the cancer stem... |