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US20060252036 |
Alteration of rab38 function to modulate mammalian pigmentation
The present invention relates to compositions and methods involving melanocytes. In particular, the present invention provides compositions and methods involving RAB38 and mutant RAB38, suitable... |
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US20100285971 |
Traceability of Cellular Cycle Anomalies Targeting Oncology and Neurodegeneration
The invention concerns a novel diagnostic and/or prognostic test for cancer. More particularly, the invention concerns the human LIV21 protein, its use as cancer diagnostic and prognostic markers.... |
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US20050250118 |
EPHX2 Genetic markers associated with galantamine
Haplotypes in the EPHX2 gene associated with cognitive response to galantamine treatment are disclosed. Compositions and methods for detecting and using these EPHX2 haplotypes in a variety of... |
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US20060257429 |
Vaccine for periodontal disease
The present invention relates to novel bacterial isolates identified by their 16S rRNA DNA, that cause periodontal disease in companion animals, and vaccines comprising such bacteria. Also... |
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US20070172840 |
Parallel microarray hybridization
A glass substrate with multiple identical microarrays is provided, for example, for the identification of genes via nucleic acid hybridization. The multiarray substrate permits the analysis, in... |
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US20080241824 |
Mutation Associated With Lacunar Strokes
The present invention relates to a method of identifying a subject predisposed to lacunar stroke. The method includes the step of identifying in the subject the presence of a thymine to cytosine... |
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US20090311677 |
Identification of contaminating bacteria in industrial ethanol fermentations
A method for determining the presence of a contaminating organism in a fermentation process includes initiating the fermentation process using a syngas and obtaining a first aliquot from the... |
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US20100034736 |
IDENTIFICATION OF CANCER STEM CELLS USING GENETIC MARKERS
The invention relates to the identification of markers for cancer stem cells. These markers can be used in a number of different ways, including diagnosis and therapy. In particular, the invention... |
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US20050221337 |
Microarrays and microspheres comprising oligosaccharides, complex carbohydrates or glycoproteins
One aspect of the present invention relates to an array, comprising a plurality of spots on a solid support, wherein each spot independently comprises a substrate attached to said solid support,... |
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US20090286244 |
Fluorescent Color Markers
The invention provides a yeast-enhanced red fluorescent protein. In an embodiment of the invention, the yeast-enhanced red fluorescent protein is monomeric and is expressible in Candida albicans.... |
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US20090170093 |
SELECTION MARKER SYSTEM AND METHOD FOR SCREENING A CHOLINE TOLERANT PLANT CELL
The present invention relates to a selection marker system for distinguishing genetically modified plant cells from wild-type plant cells comprising (a) a nucleic acid sequence coding for choline... |
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US20050069898 |
Lyophilized beads containing mannitol
Mannitol in certain weight percentages can be used to produce lyophilized beads of consistent size, consistent morphology, and reduced moisture content. These mannitol-containing lyophilized beads... |
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US20090196901 |
Tissue Engineering Methods and Compositions
The presently disclosed subject matter generally relates to methods and systems for facilitating the growth and differentiation of adipose-derived stem cells for laboratory and therapeutic... |
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US20100081130 |
Multifunctional particles providing cellular uptake and magnetic motor effect
Preparation of novel multifunctional particles and nanomaterials having a useful combination of magnetic and optical properties and biocompatibility. The internalization efficiencies in various in... |
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US20070117135 |
Method of inoculation for evaluating candidate therapies for prevention of acquisition of infectious diseases
A method of inoculating the vestibular region of the nares with virus, bacteria, fungus, or mold to ascertain whether acquisition and/or prevention of transmission of infection may occur. |
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US20100196896 |
METHOD AND A KIT FOR IDENTIFYING A HUMAN WHO HAS THE PREDISPOSITION FOR INCREASED CONSUMPTION OF CARBOHYDRATES AND METHOD FOR MANAGING THE NAMED HUMAN'S DIETARY INTAKE OF NUTRITIONAL ENERGY
A method and a kit for determining the human with genetic predisposition to increased consumption of carbohydrates and to develop metabolic, psychiatric or neurological disease or disorder, or... |
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US20100212038 |
TRANSGENIC FISH WITH TISSUE-SPECIFIC EXPRESSION
Disclosed are transgenic fish, and a method of making transgenic fish, which express transgenes in stable and predictable tissue- or developmentally-specific patterns. The transgenic fish contain... |
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US20100021894 |
Nanoparticle-Based Colorimetric Detection Of Cysteine
The invention provides methods to detect cysteine which employ oligonucleotide functionalized nanoparticles. |
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US20060134647 |
Method for elimination of false reactivities in immunoassay for Hepatitis A virus
An ancillary reducing reagent composition is used to significantly reduce and substantially eliminate the incidence of false positive results in an immunoassay for the detection of antibodies to... |
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US20090111095 |
NOVEL DIAGNOSTIC KIT FOR MALIGNANT MELANOMA
The object of the present invention is to find out another tumor marker which is useful for early diagnosis of melanoma, and provide a diagnostic kit and diagnostic method for malignant melanoma... |
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US20070299032 |
Method and Composition for Thickening Hair
The present invention provides a method for maintaining and promoting hair thickening by increasing the expression of keratinocyte growth factor (FGF-7) in hair follicle cells, and preferably... |
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US20050232918 |
Differentially expressed genes associated with obesity and type 2 diabetes
The present invention relates generally to a nucleic acid molecule which is expressed in at least the stomach, hypothalamus or liver identified using differential display techniques under... |
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US20100166710 |
Compositions and Methods for Inducing Neuronal Differentiation
The present invention provides compositions and methods for inducing neuronal cell differentiation. |
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US20090253133 |
ENHANCED T CELL RECEPTOR-MEDIATED TUMOR NECROSIS FACTOR SUPERFAMILY AND CHEMOKINE MRNA EXPRESSION IN PERIPHERAL BLOOD LEUKOCYTES IN PATIENTS WITH CROHN'S DISEASE
A method is disclosed for determining whether a human having Crohn's disease is likely to respond to a therapy targeting a TNFSF member or a cytokine by measuring the level of certain mRNAs in... |
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US20090176659 |
TRANSCRIPTIONAL ENGINEERING OF LACTOBACILLUS
The invention relates to global transcription machinery engineering to produce altered cells having improved phenotypes and methods for evaluating phenotypic diversity. |
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US20110086341 |
FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION
The invention provides novel fluorinated resorufin compounds that are of use in a variety of assay formats. Also provided are methods of using the compounds and kits that include a compound of the... |
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US20050118583 |
Novel genetic products of ashbya gossypii, associated with the mechanisms of signal transduction and especially with the improvement of vitamin b2 production
The invention relates to novel polynucleotides from Ashbya gossypii; to oligonucleotides hybridizing therewith; to expression cassettes and vectors which comprise these polynucleotides; to... |
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US20060041954 |
Genetic loci associated with fusarium solani tolerance in soybean
The invention relates to methods and compositions for identifying soybean plants that are tolerant, have improved tolerance or are susceptible to Fusarium solani infection (the causative agent of... |
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US20050048543 |
CHRNA2 genetic markers associated with galantamine response
Haplotypes in the CHRNA2 gene associated with cognitive response to galantamine treatment are disclosed. Compositions and methods for detecting and using these CHRNA2 haplotypes in a variety of... |
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US20100016364 |
METHOD OF PREDICTIVE DETERMINATION OF RESPONSIVENESS TO PHARMACOLOGICAL INTERVENTION
A diagnostic test for determining the efficacy of 5HT1 agonists in a human patient exhibiting symptoms of a cranial facial pain syndrome includes the steps of collecting a sample of saliva from... |
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US20090285758 |
IN VIVO SYSTEM TO MONITOR TISSUE RESPONSES IN BIRDS
Methods of evaluating the tissue response to an agent in birds are provided. Also disclosed are methods of monitoring exposure to agents in birds and methods of determining the efficacy of vaccines. |
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US20090197270 |
DIAGNOSTIC ASSAY FOR SPONGIFORM ENCEPHALOPATHIES
The invention provides a method of diagnosis of a spongiform encephalopathy in a diagnostic sample of a valid body tissue taken from a subject, which comprises detecting an increased proteolytic... |
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US20060003312 |
Circulating stem cells and uses related thereto
The disclosure provides, inter alia, methods for enhancing the contribution of circulating stem cells to a target tissue. Such methods may be useful for treating a variety of disorders. In a... |
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US20090220954 |
METHODS OF DIAGNOSING CARDIOVASCULAR DISEASE
Methods are disclosed for diagnosing increased risk of cardiovascular disease in a subject. |
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US20090317805 |
Proteolytic Markers as Diagnostic Biomarkers for Cancer, Organ Injury and Muscle Rehabilitation/Exercise Overtraining
The present invention identifies biomarkers that are diagnostic of nerve cell injury, organ injury, and/or neuronal disorders. Detection of different biomarkers of the invention are also... |
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US20070072185 |
Carbohydrate-binding modules of a new family
The present invention relates to non-catalytic carbohydrate-binding modules (CBM) belonging to a new family of CBM's. A CBM of the invention was found attached to a glycosyl hydrolase family 61... |
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US20060275761 |
Tryptophan hydroxylase assay
The present invention relates to methods of evaluation and detection of the expression of tryptophan hydroxylase (TPH) gene and induction of TPH by estrogen receptor-beta (ERβ) agonists, utilizing... |
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US20080085878 |
SUPEROXIDE DISMUTASE-2 EXPRESSION AND MODULATION FOR GLAUCOMA DIAGNOSIS AND THERAPY
The present invention concerns a method for diagnosing or monitoring elevated intraocular pressure or glaucoma in a patient comprising providing a biological sample from the patient and measuring... |
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US20070160545 |
Method for reducing ultraviolet light induced apoptosis
The present invention provides a method for enhancing resistance to the onset of skin damage caused by irradiation of the skin with ultraviolet light by inhibiting ultraviolet irradiation-induced... |
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US20100240673 |
EML4-ALK Fusion Gene
The present inventors found that a fusion gene present in some cancer patients is an oncogene. The present invention relates to a polypeptide as a novel fusion protein, a polynucleotide encoding... |
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US20110098188 |
BLOOD BIOMARKERS FOR PSYCHOSIS
A plurality of biomarkers determine the diagnosis of psychosis based on the expression levels in a sample such as blood. Subsets of biomarkers predict the diagnosis of delusion or hallucination.... |
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US20100136565 |
Compositions and Methods for Diagnosing Autism
Mutations located within the gene encoding the homeobox transcription factor, ENGRAILED 2 (EN2), have now been identified as molecular markers associated with susceptibility for autism and related... |
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US20090297573 |
Identifying and Modulating Molecular Pathways that Mediate Nervous System Plasticity
The present invention provides methods for identifying genes and pathways involved in plasticity. The invention applies some of these methods to identify genes that are differentially regulated in... |
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US20080045443 |
Compositions for Inhibiting plexin-A1-DAP12 interactions and Methods of Treating Inflammatory, Autoimmune or Bone Resorption Diseases Using the Same
Disclosed are compositions and methods of treating an inflammatory, autoimmune or bone resorption disease by inhibiting plexin-A1-DAP12 interaction, plexin-A1-Trem-2 interaction or DAP12-Trem-2... |
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US20100284999 |
CHARACTERIZATION OF THE CBIR1 ANTIGENIC RESPONSE FOR DIAGNOSIS AND TREATMENT OF CROHN'S DISEASE
This invention provides methods of diagnosing or predicting susceptibility to Crohn's Disease by determining the presence or absence of genetic variants. In one embodiment, the present invention... |
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US20060246446 |
Use of islet 1 as a marker for isolating or generating stem cells
The present invention provides in vitro methods of expansion and propagation of undifferentiated progenitor cells and more specifically undifferentiated progenitor cells containing Islet1, a... |
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US20090311707 |
O-GLYCANS AS DIAGNOSTIC MARKERS FOR INFLAMMATORY BOWEL DISEASE
The present invention provides diagnostic methods for inflammatory bowel disorders (e.g., Crohn's disease or ulcerative colitis) comprising assessing expression, structure and/or function of... |
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US20090311694 |
Splice variants of human IL-23 receptor (IL-23R) mRNA and use of a delta 9 isoform in predicting inflammatory bowel diseases
There is disclosed the cloning and identification of human IL-23R splice variants caused by alternative splicing of the IL-23R mRNA in human. Alternative mRNA forms occur through skipping one,... |
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US20090169535 |
TREATMENT OF EPILEPSY BY EXPRESSING ST3GAL-III
The present invention provides methods of diagnosing epilepsy in a mammal by detecting ST3 β-galactoside α-2,3-sialyltransferase 3 (ST3Gal-III) activity or by detecting for one or more mutations... |
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US20070259967 |
Methods of Diagnosis
Methods for determining whether an ADHD patient is suitable for treatment with a monoamine oxidase type B (MAO-B) inhibitor, and uses of MAO-B inhibitors in medicaments for treatment of ADHD.... |