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US20100203513 |
MICRORNA AS BIOMARKER IN CANCER
The present invention relates to the discovery of certain microRNAs that correlate with certain information regarding cancer. The microRNAs of the invention are selected from the group consisting... |
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US20090042204 |
ACNE LESION BIOMARKERS AND MODULATORS THEREOF
The present invention relates to acne lesions biomarkers/genes expression products pattern and particularly inflammatory acne lesions biomarkers and their uses, modulators thereof and the use of... |
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US20100092958 |
Methods for Determining Collateral Artery Development in Coronary Artery Disease
The present invention relates to a method for determining collateral artery development in a human subject with coronary artery disease based upon the levels of expression of markers associated... |
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US20060211684 |
Use of alpha-2 adrenergic receptor agonists
The present invention provides a strategy to compensate for deficiency in the alpha-2C receptor by administering an agonist of different receptors; the alpha-2A and/or dopamine d2 receptors. These... |
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US20100216653 |
USE OF POLYMORPHISMS IN THE TMEM132D GENE IN THE PREDICTION AND TREATMENT OF ANXIETY DISORDERS
The present invention relates to methods, compositions, kits and reagents for the diagnosis and treatment of anxiety disorders. |
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US20100055700 |
ROLE OF IL-12, IL-23 AND IL-17 RECEPTORS IN INFLAMMATORY BOWEL DISEASE
This invention provides methods of diagnosing or predicting susceptibility or protection against Inflammatory Bowel Disease in an individual by determining the presence or absence of genetic... |
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US20060182761 |
Methionine salvage pathway in Bacillus
The present invention relates to pathways for the synthesis and recycling of methylthioribose (MTR), applications in the fight against plant and vertebrate pathogens (including parasites and their... |
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US20100151471 |
METHODS OF MONITORING CONDITIONS BY SEQUENCE ANALYSIS
There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer. Provided herein are methods for using DNA... |
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US20100120030 |
Extracellular serine protease
The present invention provides a DNA encoding a TADG-14 protein selected from the group consisting of: (a) isolated DNA which encodes a TADG-14 protein; (b) isolated DNA which hybridizes to... |
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US20100330564 |
NUCLEIC ACID DETECTION METHOD AND NUCLEIC ACID DETECTION KIT
In the present invention, an amplified DNA fragment having a first substance binding site to which a first substance is specifically bindable is prepared, which amplified DNA fragment amplified by... |
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US20070077557 |
Method for identifying type-1 interferon responsive ms patients by determining trail expression
This invention relates to a method for identifying MS patients susceptible to type I-Interferon (IFN), in particular IFN-β, and for monitoring IFN therapy in MS patients by determining TRAIL gene... |
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US20100279293 |
METHODS AND COMPOSITIONS FOR IDENTIFYING INCREASED RISK OF DEVELOPING FRAGILE X-ASSOCIATED DISORDERS
The present invention provides compositions and methods of identifying a subject as having an increased risk of developing fragile X-associated tremor and ataxia syndrome (FXTAS) or identifying a... |
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US20050130165 |
Polymorphism of soati useful for identifying risk of developing alzheimer's disease
Based on the unexpected association of a SOAT1 gene polymorphism with reduced genetic risk for a neurodegenerative disease, in particular Alzheimer's disease, the present invention provides a... |
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US20090226459 |
ROLE OF FGF-19 IN CANCER DIAGNOSIS AND TREATMENT
The present invention relates, in part, to the discovery that human FGF19 is amplified in a number of cancers, including liver and esophageal cancers, and that this amplification correlates with... |
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US20060084094 |
Conjugates for use in hepatocyte free uptake assays
The present invention provides methods of identifying oligomeric compounds, such as siRNA and double-stranded RNA compounds, having bioactivity in vivo, and kits. |
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US20060099591 |
Diagnosis of chronic rejection
Methods are disclosed for, early diagnosing chronic rejection (CR) in a transplanted subject, monitoring CR in a transplanted subject at risk of developing CR, preventing, inhibiting, reducing or... |
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US20100129815 |
IDENTIFICATION OF CARDIAC SPECIFIC MYOSIN LIGHT CHAIN KINASE
The subject invention pertains to the association of a MLCK homologue with cardiac tissue and methods of identifying candidate compounds that can modulate the activity of this MLCK homologue and... |
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US20050233365 |
Method for producing plasmid DNA on a manufacturing scale
A method for producing plasmid DNA on a manufacturing scale uses Escherichia coli K-12 strain JM108. The process results in high yield and homogeneity of plasmid DNA. |
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US20090176238 |
Cynomolgus Toll-Like Receptor 3
Isolated polynucleotides encoding Cynomolgus monkey Toll-Like Receptor 3 (cynoTLR3), polypeptides obtainable from expression of these polynucleotides, recombinant cells, methods and uses of these... |
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US20100098638 |
RIP140 Regulation of Diabetes
Inhibition of RIP140 increases glucose transport. Compounds that inhibit RIP140 expression or activity are useful for treating disorders associated with aberrant glucose transport (e.g.,... |
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US20050287547 |
Embryonic stem cell markers and uses thereof
The present invention provides methods and reagents for identification, separation and characterization of embryonic stem cells using markers previously recognized as germ cell specific. One... |
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US20080159994 |
METHODS FOR EMBRYONIC STEM CELL CULTURE
The invention relates to a method of cell culture comprising providing a pluripotent ES cell encapsulated within a support matrix to form a support matrix structure, maintaining the encapsulated... |
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US20080206343 |
Hepatocytes and Chondrocytes from Adherent Placental StemCells; And CD34+ ,CD45- Placental Stem Cell-Enriched Cell Populations
Provided herein are methods and compositions for the production of hepatocytes from placenta stem cells. Further provided herein is the use of such hepatocytes in the treatment of, and... |
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US20070007512 |
Bio-inorganic conjugates
A method for producing a bio-inorganic conjugate is provided comprising supplying a plurality of inorganic particles that are axially anisotropic; and positioning biomolecules intermediate the... |
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US20080160522 |
Primer for Detecting Food Poisoning and Method for Rapid Detection of Food Born Pathogene
The present invention relates to a primer of detecting a food-borne pathogen, and to a method of detection for food poisoning. In particular, the invention relates to a PCR primer which is... |
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US20060204992 |
Method for determining hair cycle markers
The invention relates to a method for determining hair cycle markers in vitro, test kits and biochips which are used to determine hair cycle markers and to the use of proteins, mRNA molecules,... |
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US20110091900 |
METHOD FOR DETERMINING DNA COPY NUMBER BY COMPETITIVE PCR
The present invention relates to a method for determining the number of copies of DNA at a specific locus. The method comprises the step of co-amplifying a DNA sample of an exploratory species... |
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US20100273713 |
Diagnosis and Treatment of Congenital Heart Defects Using NELL1
The present invention provides diagnostic methods for detecting congenital heart defects, or increased risk thereof, based on the Nell1 gene, RNA and protein. The methods include obtaining a... |
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US20110111394 |
CTGF AS A BIOMARKER, THERAPEUTIC AND DIAGNOSTIC TARGET
The invention provides CTGF which is associated with the cardiovascular diseases and hematological diseases. The invention also provides assays for the identification of compounds useful in the... |
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US20100235933 |
Kaspp (lrrk2) gene, its production and use for the detection and treatment of neurodegenerative disorders
The present invention refers to a newly discovered gene named KASPP for Kinase Associated with Parkinsonism with Pleiomorphic Pathology or alternatively named LRRK2 for Leucine-Rich Repeat Kinase... |
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US20110059438 |
Method of Preparing DNA Fragments and Applications Thereof
A method of preparing DNA fragments, which entails at least the following steps of: a) preparing double-stranded DNA fragments from a sample of nucleic acids to be analyzed,b) ligating the ends of... |
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US20090136921 |
Association of Breast Cancer DNA Methylation Profiles with Hormone Receptor Status and Response to Tamoxifen
Particular embodiments provide novel and clinically useful DNA methylation predictors of hormone receptor status, and predictors of response to endocrine (e.g., hormonal) and non-endocrine breast... |
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US20050069936 |
Diagnostic markers of depression treatment and methods of use thereof
The present invention relates to methods for the diagnosis and evaluation of depression treatment. In particular, patient test samples are analyzed for the presence and amount of members of a... |
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US20050124008 |
Homogeneous competition assays
Homogeneous assays wherein an unlabeled analyte is detected by displacing a more weakly binding tracer from a binding partner are described. The tracer has signal generating properties which... |
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US20070101447 |
Diagnostic tests for the detection of motor neuropathy
The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to diagnose distal hereditary motor neuropathy... |
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US20090220453 |
ENHANCING STEM CELL MOBILIZATION
This invention relates to methods and compositions for enhancing hematopoietic stem cell mobilization by inhibiting early growth response-1 (egr1) activity. |
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US20100035239 |
Compositions for use in identification of bacteria
The present invention provides oligonucleotide primers and compositions and kits containing the same for rapid identification of bacteria by amplification of a segment of bacterial nucleic acid... |
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US20100022440 |
VH4 Codon Signature For Multiple Sclerosis
The present invention provides for the diagnosis and prediction of multiple sclerosis (MS) in subject utilizing a unique a codon signature in VH4 expressing B cells that has now been associated... |
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US20090233286 |
Methods of diagnosis and prognosis of pancreatic cancer
Disclosed herein are methods of diagnosing pancreatic cancer in a subject. Also provided are methods of monitoring the efficacy of a therapeutic treatment of pancreatic cancer as well as methods... |
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US20090011406 |
Method of Judging Fatigue
A method of judging fatigue, which comprises judging fatigue by using, as an index, a value obtained by quantitatively analyzing an adenine nucleotide in a sample to be measured. |
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US20090081648 |
Detection and analysis of influenza virus
An assay comprising more than one primer pair and more than one detection probe, a low copy number synthetic amplicon corresponding to each of the primer pairs. The assay can detect and... |
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US20100029559 |
Method for achieving desired glial growth factor 2 plasma levels
The present invention relates to administering glial growth factor 2 (GGF2) to a patient in need thereof, to achieve serum levels of GGF2 within a desired therapeutic window determined based on... |
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US20050202494 |
Catalases
The invention relates to catalases and to polynucleotides encoding the catalases. In addition methods of designing new catalases and method of use thereof are also provided. The catalases have... |
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US20100162422 |
Novel therapeutic and diagnostic products and methods
The present invention relates to the use of p11 as a drug target as well as a tool for the diagnosis, treatment and development of p11/5-HT receptor related disorders. The invention further... |
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US20050277140 |
Biomarkers of chronic pelvic pain syndrome
The present invention provides biomarkers of chronic pelvic pain syndrome for use in diagnosis, drug screening, therapy monitoring, research and therapeutic applications. In particular, the... |
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US20080003222 |
Inhibitors for L1 and Adam10 for the Treatment of Carcinomas
Described is a pharmaceutical composition comprising a compound(s) interfering with the biological activity of L1 and/or ADAM10 or their expression. Also described is the use of said compound(s)... |
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US20070053890 |
Canine embryonic stem cells
The invention relates to canine embryonic stem cells, methods of cultivation and propagation of the cells, and production of differentiated cells. The embryonic stem cells may be obtained by... |
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US20090005296 |
Ammonium/Ammonia Transporter
The present invention relates to methods and means for ammonia and/or ammonium transport in a variety of organisms, including mammals, yeast and plants. In particular, the present invention is... |
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US20070141066 |
Method for Diagnosing, Prognosing and Treating Glioma
The invention provides generally a method of monitoring, diagnosing, prognosing and treating glioma. Specifically, the invention provides for three (3) prognostic subclasses of glioma, which are... |
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US20100183520 |
NETRIN-1 AS A BIOMARKER OF INJURY AND DISEASE
Detection and diagnosis of injury and/or disease in a subject can be key to preventing irreversible damage and death. Methods of aiding detection and assessment of a disease or condition in a... |