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US20100330559 FORENSIC IDENTIFICATION  
The invention provides allelic ladder mixtures and individual alleles suitable for use in such mixtures. The allelic ladder mixtures give improved identification and distinguishing capabilities,...
US20140030715 METHOD OF USING BOTH MIR-196A AND MIR-196B AS BIOMARKERS FOR DETECTING ORAL CANCER  
A method of using miR-196a and miR-196b as biomarkers for oral cancer detection is provided with the steps of analyzing a sample from each of a plurality of human beings in terms of miR-196a and...
US20110021370 SALIVARY PROTEIN BIOMARKERS FOR HUMAN ORAL CANCER  
The present invention relates to the identification of novel oral cancer and periodontal disease biomarkers. Further, the present invention provides novel methods of diagnosing and for providing a...
US20130295580 ORAL CANCER POINT OF CARE DIAGNOSTICS  
A point of care diagnostic test, device and disposables for determining a patient risk for oral cancer in the same visit that a sample is collected.
US20100297632 UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER  
The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocyte cell of said mammal, and the...
US20110312509 BIOMARKERS DOWNREGULATED IN PROSTATE CANCER  
Biomarkers are identified by analyzing gene expression data using support vector machines (SVM), recursive feature elimination (RFE) and/or linear ridge regression classifiers to rank genes...
US20110045475 UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER  
The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocytic cell of said mammal, and the...
US20110123990 Methods To Predict Clinical Outcome Of Cancer  
The present invention provides methods to determine the prognosis and appropriate treatment for patients diagnosed with cancer, based on the expression levels of one or more biomarkers. More...
US20110136129 ASSESSING ATYPICAL HYPERPLASIA PATIENTS FOR THE RISK OF DEVELOPING BREAST CANCER  
This document provides methods and materials involved in assessing the risk of developing breast cancer in patients with atypical hyperplasia. For example, methods and materials for using the...
US20100316629 Use of gene expression profiling to predict survival in cancer patient  
Gene expression profiling in multiple myeloma patients identifies genes that distinguish between patients with subsequent early death or long survival after treatment. Poor survival is linked to...
US20140017227 GENE SIGNATURES FOR USE WITH HEPATOCELLULAR CARCINOMA  
The present invention provides a method for predicting prognosis of hepatocellular carcinoma patients based on measurement of the relative level of expression of a combination of 15 immune genes...
US20120028264 METHOD FOR USING GENE EXPRESSION TO DETERMINE PROGNOSIS OF PROSTATE CANCER  
Molecular assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis...
US20110165582 MOLECULAR METHOD FOR DIAGNOSIS OF COLON CANCER  
Methods for diagnosing or detecting cancerous colon tissue. A panel of 17 specific marker genes are provided. The overexpression of some of these marker genes compared to their expression in...
US20110086805 IN VITRO METHOD FOR DIAGNOSING SKIN CANCER  
The present invention relates to an in vitro method for identifying an individual suffering from or having a predisposition to skin cancer, characterized in that it comprises the step of analysing...
US20110076274 MATERIALS AND METHODS RELATING TO A G-PROTEIN COUPLED RECEPTOR  
The present inventors demonstrate that the G-protein coupled receptor 55 (GPR55) is highly expressed in human aggressive breast cancer cells, and that the expression level may be correlated with...
US20140024811 CANCER DETECTION  
Provided are methods of detecting cancer or pre-cancerous conditions in patients comprising assaying a patient sample for an elevated level of target molecules representative of expression of...
US20110086796 METHODS FOR PREDICTING THE DEVELOPMENT AND RESOLUTION OF ACUTE RESPIRATORY DISTRESS SYNDROME  
The subject invention features methods for predicting whether a subject at risk of developing Acute Respiratory Distress Syndrome (ARDS) will develop ARDS by determining the amount of elafin...
US20110224088 Biomarkers for subtypes of cervical cancer  
The present invention relates to biomarkers for chemoradioresistant subtypes of cervical cancer. In particular the present invention relates to a method for predicting a predisposition to a...
US20100297014 METHOD OF DETECTING THE RISK OF CANCER USING GENETIC MARKERS  
An ex vivo method for the detection of the risk of cancer in a patient, comprising the step of: detecting the expression level of one or more gene sequences identified herein in Table 1, or the...
US20150037251 MAMMALIAN HOMOLOGUES OF FLOWER, THEIR USE IN CANCER DIAGNOSTICS, PREVENTION AND TREATMENT  
The invention relates inhibiting nucleic acids directed at mammalian homologues of the Drosophila fwe gene (Flower) and to antibodies against the respective proteins, and their use in diagnosing,...
US20110070268 Method  
Methods for characterisation of patients as responders or non-responders to therapy based on differential expression of one or more genes are provided. Gene expression profiles, microarrays...
US20110195848 GENE EXPRESSION AND BREAST CANCER  
This invention provides methods and reagents for determining breast cancer patient prognosis and/or diagnosis of tumor aggressiveness, disease-free survival times and reduced patient disease-free...
US20110300536 GENE MARKER AND METHOD FOR DETECTION OF ORAL CANCER  
A gene marker for the detection of oral cancer, comprising methylated CpG sites in target genes, is provided. The CpG sites in the target genes are selected from a group consisting of the...
US20110086349 Proliferation Signatures and Prognosis for Gastrointestinal Cancer  
This invention relates to methods and compositions for determining the prognosis of cancer in a patient, particularly for gastrointestinal cancer, such as gastric or colorectal cancer....
US20130109017 MULTIPLE MYELOMA PROGNOSIS AND TREATMENT  
Disclosed herein are diagnostic and prognostic methods for determining the overall survival, and therapeutic regimes, for multiple myeloma patients. The methods involve the detection of PTHR1 gene...
US20130344486 METHOD OF DIAGNOSING BREAST CARCINOMA  
The present invention relates to methods of diagnosing a breast carcinoma, determining the prognosis of a patient diagnosed with breast carcinoma and determining the efficacy of a treatment...
US20110143361 PREDICTIVE VALUE OF NUCLEAR EXCISION REPAIR GENES FOR CANCER SURVIVAL  
Patients who have their cancer surgically removed are at risk for recurrence, even though currently free of disease. Lung cancer patients with higher activity of a nuclear excision repair gene...
US20140141423 miRNAs Differentially Expressed in Lymph Nodes from Cancer Patients  
The present invention provides diagnostics and/or prognostic methods by identifying miRNAs that are differentially expressed or mis-regulated in various states of diseased, normal, cancerous,...
US20100297655 SOCS-1 GENE METHYLATION IN CANCER  
Methods are provided for identifying a cell exhibiting unregulated growth associated with methylation-silenced transcription of a suppressor of cytokine signaling (SOCS)/cytokine-inducible SH2...
US20110027184 PROTEIN C PATHWAY ASSOCIATED POLYMORPHISMS AS RESPONSE PREDICTORS TO ACTIVATED PROTEIN C OR PROTEIN C-LIKE COMPOUND ADMINISTRATION  
The invention provides methods, nucleic acids, compositions and kits for predicting a subject's response to treatment with activated protein C or protein C like compound to identify subjects...
US20110129844 Use of Activating Transcription Factor-2 (ATF2) for Detecting Skin Cancer  
The present invention is based on the discovery of the tumor suppressor role of activating transcription factor 2 (ATF2) in non-melanoma skin cancer development. Accordingly, the invention...
US20140256564 METHODS OF USING HUR-ASSOCIATED BIOMARKERS TO FACILITATE THE DIAGNOSIS OF, MONITORING THE DISEASE STATUS OF, AND THE PROGRESSION OF TREATMENT OF BREAST CANCERS  
The present invention relates to methods of identifying gene targets, including methods of using ribonucleoprotein (RNP) immunoprecipitation-microarrays to identify cancer gene targets, such as...
US20100297619 GENETIC PREDICTION OF SCHIZOPHRENIA SUSCEPTIBILITY  
Provided are methods of determining the likelihood that a patient will be diagnosed with schizophrenia.
US20110287957 METHODS AND KITS FOR DIAGNOSING COLORECTAL CANCER  
The invention pertains to a method for early detection and screening of colorectal cancer in human subjects based on RNA isolated from blood obtained from said subject. According to the invention,...
US20120053079 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER  
The present invention relates to methods and compositions for diagnosing and treating cancer, such as breast cancer and skin cancer.
US20150017640 Combinations of Molecular Markers in Prostate Cancer providing a Diagnostic Tool with Improved Sensitivity/Specificity  
The present invention relates to methods for in vitro establishing, or diagnosing, high grade or low grade prostate cancer in a sample, preferably from a readily obtainable sample such as an...
US20110171323 METHODS AND KITS TO PREDICT PROGNOSTIC AND THERAPEUTIC OUTCOME IN SMALL CELL LUNG CANCER  
Disclosed herein are methods used in the identification of cancer patients likely or unlikely to respond to systemic chemotherapy, methods of treating cancer patients based upon the...
US20150094224 METHODS FOR THE DIAGNOSIS OR PROGNOSIS OF BREAST CANCER  
Methods for detecting, diagnosing and monitoring an epithelial cancer in a patient are described comprising measuring in a sample from the patient Ep-ICD polypeptides and Ep-ICD polynucleotides....
US20120065147 USE OF THE GTPASE RAB27B TO DIAGNOSE AND TREAT POOR PROGNOSIS ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER  
The present invention relates to evaluating the prognosis of patients with estrogen receptor-positive breast cancer on the basis of Rab27B expression. The invention further relates to a kit...
US20110160080 Diagnosis of Melanoma and Solar Lentigo by Nucleic Acid Analysis  
The present invention provides methods for diagnosing melanoma and/or solar lentigo in a subject by analyzing nucleic acid molecules obtained from the subject. The present invention also provides...
US20100330580 METHOD FOR THE IN VITRO DIAGNOSIS OR PROGNOSIS OF TESTICULAR CANCER  
A method for in vitro diagnosis or prognosis of testicular cancer in a biological sample from a patient suspected of suffering from testicular cancer, having a step of detecting the presence or...
US20130023427 METHODS FOR ASSESSING GENOMIC INSTABILITIES IN TUMORS  
The invention generally relates to methods for assessing genomic instabilities in a tumor sample. The invention may further be used to predict grade, stage, and prognosis of cancer in a patient....
US20130130927 DETECTION AND QUANTIFICATION OF MICRORNAS IN THE CIRCULATION AND THE USE OF CIRCULATING MICRORNAS AS BIOMARKERS FOR CANCER  
The present invention relates to the identification of circulating miRNAs as biomarkers suitable for use in the diagnosis and prognosis of a number of cancers, in particular breast cancer. In...
US20130165331 CHROMOSOME COPY NUMBER GAIN AS A BIOMARKER OF UROTHELIAL CARCINOMA LETHALITY  
Diagnostic assays for medically classifying cancer patients are provided. The method comprises assessing a tissue sample of the patient for the presence of a copy number gain of chromosome regions...
US20120295807 CHROMOSOME COPY NUMBER GAIN AS A BIOMARKER OF UROTHELIAL CARCINOMA LETHALITY  
Diagnostic assays for medically classifying cancer patients are provided. The method comprises assessing a tissue sample of the patient for the presence of a copy number gain of chromosome regions...
US20150072883 Detection and quantification of microRNAs in the circulation and the use of circulating microRNAs as biomarkers in cancer  
The present invention relates to the identification of biomarkers suitable for use in the diagnosis and prognosis of a number of cancers. In addition, the invention relates to improved methods for...
US20120040353 Detection and quantification of microRNAs in the circulation and the use of circulating microRNAs as biomarkers in cancer  
The present invention relates to the identification of biomarkers suitable for use in the diagnosis and prognosis of a number of cancers. In addition, the invention relates to improved methods for...
US20100317726 SLCO1B3 GENOTYPE  
The invention relates methods of identifying and predicting inter-patient differences in prognostic prediction for survival in androgen independent prostate cancer. It further related to methods...
US20110275534 MicroRNA-Based Methods and Compositions for the Diagnosis, Prognosis and Treatment of Ovarian Cancer Using a Real-Time PCR Platform  
Methods and compositions for the diagnosis, prognosis and/or treatment of ovarian cancer are disclosed.
US20110097727 DNA MARKERS FOR MANAGEMENT OF CANCER  
A method is provided for assessing allelic losses and hypermethylation of genes in CpG tumor promotor region on specific chromosomal regions in cancer patients, including melanoma, neuroblastoma...