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US20150152510 HIGH RESOLUTION MELTING ANALYSIS AS A PRESCREENING TOOL  
Compositions and methods for determining an increased likelihood of a response to a targeted treatment of a cancer disease including isolating genomic DNA from a patient sample, amplifying a...
US20140017682 HIGH RESOLUTION MELTING ANALYSIS AS A PRESCREENING TOOL  
Compositions and methods for determining an increased likelihood of a response to a targeted treatment of a cancer disease including isolating genomic DNA from a patient sample, amplifying a...
US20140274777 LIPID DROPLET PROTEIN MARKERS FOR ALGAL OIL ACCUMULATION  
The application relates to apparatuses, methods and kits for detecting and quantifying oil content in algal samples.
US20150225796 METHYLATION ANALYSIS ON SELF-SAMPLES AS TRIAGE TOOL FOR HPV-POSITIVE WOMEN  
The inventors now have developed a (molecular) diagnostic assay based on detection of alterations in markers MAL and hsa-mi R124, in particular promoter hypermethylation, to identify human...
US20140220564 TT1 AND TTG1 Control Seed Coat Color In Brassica  
Seed coat color is a very important trait in oilseed type Brassica crops. Identification of the genes controlling the seed coat color is essential to the manipulation of these genes to develop new...
US20110104669 METHOD TO PREDICT IRIS COLOR  
The invention comprises a method to predict iris color of a human from a nucleic acid/protein sample comprising assaying for one or more polymorphisms in the region 5′ proximal of the OCA2 gene up...
US20120094292 FORENSIC IDENTIFICATION  
The invention provides allelic ladder mixtures and individual alleles suitable for use in such mixtures. The allelic ladder mixtures give improved identification and distinguishing capabilities,...
US20110269128 FORENSIC IDENTIFICATION  
The invention provides allelic ladder mixtures and individual alleles suitable for use in such mixtures. The allelic ladder mixtures give improved identification and distinguishing capabilities,...
US20140178438 INDIVIDUALIZED VACCINES FOR CANCER  
The present invention relates to the provision of vaccines which are specific for a patient's tumor and are potentially useful for immunotherapy of the primary tumor as well as tumor metastases....
US20150110897 Sperm Protein as a Detection Biomarker of Early Stage Ovarian Cancer  
This disclosure provides a method for determining if a patient is likely to, or not likely to, experience ovarian cancer utilizing SP17 as a biomarker. It also provides methods and therapies to...
US20120231453 Brownian Microbarcodes for Bioassays  
An encoded microparticle carrying a spatial code is provided; and a set of encoded microparticles are provided with distinguishable spatial codes, wherein the codes comply with a pre-determined...
US20140066324 GENE EXPRESSION SIGNATURE IN SKIN PREDICTS RESPONSE TO MYCOPHENOLATE MOFETIL  
Described herein are methods and compositions for identifying patients with SSc or scleroderma who are responders to MMF treatment.
US20130071842 Hypermethylation Biomarkers for Detection of Head and Neck Squamous Cell Cancer  
Differentially methylated oral squamous cell carcinoma (OSCC) biomarkers, identified in-vitro and validated in well-characterized surgical specimens, have shown poor clinical correlation in...
US20130090257 PATHWAY ANALYSIS FOR PROVIDING PREDICTIVE INFORMATION  
A method for assigning ranking scores to pathways in a set of pathways for classifying patients is disclosed. The method comprises the steps of comparing biomolecular datasets from different...
US20120264720 IDENTIFICATION AND TREATMENT OF CANCER SUBSETS  
Methods of predicting whether or not a tumor will be responsive to IP6 treatment, methods of treating patients with cancer using IP6, methods of predicting the progression of a disease, and kits...
US20140302497 GENE CONTROLLING FRUIT COLOR PHENOTYPE IN PALM  
Methods, compositions, and kits for predicting and controlling fruit color in palm.
US20120114767 System and Method for Diagnosis and Treatment of Neuropsychiatric Disorders  
An assay for a GCH1 allele and associated genotype for the screening, prediction, diagnosis, prognosis, treatment and treatment response of psychiatric, neuropsychiatric, and neurological...
US20130189676 USE OF GENETIC MODIFICATIONS IN HUMAN GENE CHK1 WHICH CODES FOR CHECKPOINT KINASE 1  
The invention relates to an in vitro method for predicting disease risks, progression of diseases, drug risks, success of treatment and for finding drug targets by looking for one or more genetic...
US20130023440 Polynucleotides Associated With Age-Related Macular Degeneration and Methods for Evaluating Patient Risk  
The present invention provides for certain polynucleotide sequences that have been correlated to AMD. These polynucleotides are useful as diagnostics, and are preferably used to fabricate an...
US20110177957 Polymorphisms Associated With Age-Related Macular Degeneration And Methods For Evaluating Patient Risk  
The present invention provides for certain polynucleotide sequences that have been correlated to AMD. These polynucleotides are useful as diagnostics, and are preferably used to fabricate an...
US20100305082 Use of FKBPL gene to identify a cause of infertility  
Fertility problems affect (1 in 10) couples in Western society, making it one of the most common serious health issues. Despite this, little is known about the causes of infertility, and thus...
US20140011695 MARKERS FOR IDENTIFYING BREAST CANCER TREATMENT MODALITIES  
The present invention includes methods for identifying patients who will be resistant to endocrine therapy during breast cancer treatment and determining patient outcome. The methods are based on...
US20130040824 DETECTION OF GENETIC OR MOLECULAR ABERRATIONS ASSOCIATED WITH CANCER  
Biological samples including cell-free DNA fragments are analyzed to identify imbalances in chromosomal regions, e.g., due to deletions and/or amplifications in a tumor. Multiple loci are used for...
US20150045237 METHOD FOR IDENTIFICATION OF THE SEQUENCE OF POLY(A)+RNA THAT PHYSICALLY INTERACTS WITH PROTEIN  
The invention relates to an in vitro method for identifying the sequence of one or more poly(A)+RNA molecules that physically interacts with protein. The present invention provides a method to...
US20130273532 UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER  
The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocyte cell of said mammal, and the...
US20140045853 MATERIALS, METHODS, AND SYSTEMS FOR TREATING CANCER  
Aspects of the invention relate to methods of treatment, and to kits and systems for the same including materials for determining that an individual is susceptible to cancer and if warranted...
US20150018323 3B-HYDROXYSTEROID DEHYDROGENASE IN STEROID-DEPENDENT DISEASE  
Methods and kits for characterizing a subject having a steroid-dependent disease such as prostate cancer are described. A method of treating a steroid-dependent disease in a subject by obtaining a...
US20150250770 LKB1 AS PREDICTIVE MARKER OF EVEROLIMUS EFFICACY IN BREAST CANCER  
Method for identifying a breast cancer likely to respond to treatment with everolimus comprising the following steps: Measuring the level of expression of the LKB 1 gene in a breast tumour sample...
US20140162256 COMPOSITIONS AND METHODS FOR THE DETECTION OF ANAPLASMA PLATYS  
Described herein are improved diagnostic tools for veterinary and human use which can be used for serodiagnosing A. platys in mammals, particularly in members of the Canidae family and in humans....
US20140371256 PERSONALIZED PAIN MANAGEMENT AND ANESTHESIA: PREEMPTIVE RISK IDENTIFICATION AND THERAPEUTIC DECISION SUPPORT  
Methods and compositions disclosed herein generally relate to methods of improving clinical and economic outcomes to address adverse effects related to anesthesia, analgesics, opioids, and...
US20150110718 METHODS AND KITS FOR DETERMINING A PLACEBO PROFILE IN SUBJECTS FOR CLINICAL TRIALS AND FOR TREATMENT OF PATIENTS  
The present invention is directed to methods and assays for identifying subjects participating in clinical trials that may exhibit a placebo response and identifying treatments for subjects with...
US20110143962 METHOD OF EVALUATING ORAL CANCER RISK IN HUMAN  
A method of providing a risk evaluation and diagnosis of human oral cancer, by examining at the presence in human saliva sample of a combination of particulate nucleic acids from bacteria, virus,...
US20140274773 SYSTEMS AND METHODS FOR EMPLOYING PODOCALYXIN AND TRA HUMAN STEM CELL MARKERS AS PROGNOSTIC MARKERS FOR AGGRESSIVE AND METASTATIC CANCER  
The invention relates to systems and methods to detect podocalyxin-expressing and TRA-expressing cancer stem cells or cancer cells with stem cell-like properties in a tissue cell sample obtained...
US20150072866 MARKER PANEL FOR DETECTING CANCER  
Provided herein is technology relating to detecting cancer and particularly, but not exclusively, to methods for detecting colorectal cancer by evaluating multiple markers in paired plasma and...
US20130338025 USE OF GENE EXPRESSION PROFILING TO PREDICT SURVIVAL IN CANCER PATIENT  
Gene expression profiling in multiple myeloma patients identifies genes that distinguish between patients with subsequent early death or long survival after treatment. Poor survival is linked to...
US20140237630 SCREENING METHOD  
The present invention provides a method of screening a mammal for the onset or predisposition to the onset of a neuropsychiatric disorder. More particularly, the present invention provides a...
US20130289095 SYNTHETIC LETHALITY IN CANCER  
There is described herein compounds, compositions and methods for inducing synthetic lethality in a cancer cell(s).
US20130266939 SYSTEMS AND METHODS FOR STUDYING INFLAMMATION-DRUG INTERACTIONS  
The present disclosure provides compositions, systems, and tools for modeling liver inflammation and methods of using the same. The disclosure provides micropatterned hepatocyte co-cultures where...
US20150057181 MICRORNA SIGNATURES INDICATIVE OF IMMUNOMODULATING THERAPY FOR MULTIPLE SCLEROSIS  
The present invention provides methods, systems, and kits for evaluating multiple sclerosis (MS) in a patient. Particularly, the invention provides convenient miRNA-based tests for evaluating a...
US20120214682 MICRORNA SIGNATURES INDICATIVE OF IMMUNOMODULATING THERAPY FOR MULTIPLE SCLEROSIS  
The present invention provides methods, systems, and kits for evaluating multiple sclerosis (MS) in a patient. Particularly, the invention provides convenient miRNA-based tests for evaluating a...
US20130252837 METHOD FOR MEASURING RESISTANCE OR SENSITIVITY TO DOCETAXEL  
The present invention relates to novel and useful methods that predict or monitor a patient's response to a molecule of the taxoid family by measuring the increase or decrease of specific genetic...
US20140235458 METHODS AND TOOLS FOR THE DIAGNOSIS AND PROGNOSIS OF UROGENITAL CANCERS  
The present invention provides a microarray useful as a tool in the diagnosis and/or prognosis of certain types of cancers, particularly urogenital cancers. The microarray can include a plurality...
US20140017227 GENE SIGNATURES FOR USE WITH HEPATOCELLULAR CARCINOMA  
The present invention provides a method for predicting prognosis of hepatocellular carcinoma patients based on measurement of the relative level of expression of a combination of 15 immune genes...
US20130130246 METHODS FOR THE DETECTION, VISUALIZATION AND HIGH RESOLUTION PHYSICAL MAPPING OF GENOMIC REARRANGEMENTS IN BREAST AND OVARIAN CANCER GENES AND LOCI BRCA1 AND BRCA2 USING GENOMIC MORSE CODE IN CONJUNCTION WITH MOLECULAR COMBING  
Methods for detecting genomic rearrangements in BRCA1 and BRCA2 genes at high resolution using Molecular Combing and for determining a predisposition to a disease or disorder associated with these...
US20120244528 Susceptibility Genes for Age-Related Maculopathy (ARM) on Chromosome 10q26  
Allelic variations in the genes PLEKHA1 and LOC387715 are identified herein as risk factor for Age Related Maculopathy (ARM). A method is therefore provided for identifying a risk of development...
US20120295256 WEIGHT MANAGEMENT GENETIC TEST SYSTEMS AND METHODS  
Disclosed herein is a nutritional genomic weight management algorithm running on a computer system, and more specifically, a nutritional genomic weight management algorithm where an analysis of a...
US20140256633 Relaxin Proteins For Use In The Diagnosis, Prevention or Treatment of Multiple Sclerosis  
The present invention relates to the use of one or more Relaxin proteins in methods for diagnoses and treatment of multiple sclerosis. The invention also provides compositions for use in...
US20120129167 TRUNCATED CD20 PROTEIN, DELTACD20  
The present invention relates in particular to a protein from an alternative splicing of the gene encoding CD20, the nucleic acid sequences encoding the protein according to the invention, a...
US20140378334 METHOD FOR QUANTIFYING RENAL MARKERS BY ASSAYING URINE  
The invention pertains to a method of in vitro diagnosis of pathologies in a patient. According to the invention, the method comprises the following steps: a) obtaining a urine sample from said...
US20140366221 Methods of Controlling Seed Size in Plants  
This invention relates to the identification of a regulator protein (termed CYP78A6, or EOD3) which controls the size of plant seeds and organs in Arabidopsis and other plants. Manipulation of...