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US20140271542 |
GENETIC MARKER FOR PREDICTING PROGNOSIS IN PATIENTS INFECTED WITH HEPATITIS C VIRUS
The present invention provides methods and materials for predicting the clinical outcome of a hepatitis C virus (HCV) infection. In particular, the invention relates to methods and materials for... |
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US20140141410 |
FELINE LEUKEMIA VIRUS TRANS-MEMBRANE PROTEIN P15E FOR DIAGNOSIS OF FELV INFECTION
The invention provides for a method for the detection of FeLV infection in a patient, wherein a sample obtained from the patient is contacted in-vitro with a recombinant transmembrane p15E protein... |
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US20130287832 |
SOLUBLE NEEDLE ARRAYS FOR DELIVERY OF INFLUENZA VACCINES
Influenza vaccines are administered using solid biodegradable microneedles. The microneedles are fabricated from the influenza vaccine in combination with solid excipient(s) and, after penetrating... |
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US20140271713 |
METHOD FOR KEEPING A FOOD AND MOUTH DISEASE VACCINE AVAILABLE FOR EMERGENCY VACCINATION
The present invention pertains to a method for keeping a foot-and-mouth disease vaccine available for emergency vaccination of animals against foot-and-mouth disease, the vaccine comprising a... |
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US20130109010 |
METHOD FOR DETECTION OF INFECTION WITH HUMAN CYTOMEGALOVIRUS
A novel means by which HCMV infection can be detected with a high sensitivity and whose practicality is high is disclosed. The present inventors synthesized as many as 15 kinds of HCMV proteins in... |
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US20140065600 |
METHOD OF EVALUATING ORAL CANCER RISK IN HUMAN
A method of providing a risk evaluation and diagnosis of human oral cancer, by examining at the presence in human saliva sample of a combination of particulate nucleic acids from bacteria, virus,... |
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US20140329230 |
METHODS FOR DETECTING HUMAN PAPILLOMAVIRUS AND PROVIDING PROGNOSIS FOR HEAD AND NECK SQUAMOUS CELL CARCINOMA
Methods and kits for diagnosing and determining prognosis of head and neck squamous cell carcinoma are described. An exemplary method for diagnosing head and neck squamous cell carcinoma (HNSCC)... |
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US20140134600 |
BIOMARKERS ASSOCIATED WITH DEVELOPMENT OF HEPATOCELLULAR CARCINOMA IN PATIENTS WITH HEPATITIS B VIRUS INFECTION, AND METHOD FOR DETECTION THEREOF
The present invention is intended to provide a method for predicting risk of hepatocellular carcinoma (HCC) in hepatitis B virus (HBV)-infected patients with a high accuracy. More specifically,... |
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US20120282217 |
FOOT AND MOUTH DISEASE VIRUS (FMDV) CONSENSUS PROTEINS, CODING SEQUENCES THEREFOR AND VACCINES MADE THEREFROM
Provided herein is a nucleic acid comprising consensus amino acid sequence of foot-and-mouth disease FMDV VP1-4 coat proteins of FMDV subtypes A, Asia 1, C, O, SAT1, SAT2, and SAT3 as well as... |
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US20150161359 |
METHODS FOR SAFETY TESTING
The invention provides improved methods for the safety testing of compositions which comprise biological products produced in a host cell, such as vaccine antigens or recombinant proteins. |
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US20120021936 |
BIOMARKERS FOR DENGUE
The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying dengue status in a patient. In particular, the biomarkers of this invention are... |
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US20140329792 |
SYNTHETIC CATALASE/SUPEROXIDE DISMUTASE MIMETICS AND METHODS FOR TREATING VIRAL INFECTIONS
The invention provides for the treatment of disorders related to viral infection, using salen manganese compounds. |
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US20120129152 |
Diagnostic method for the prediction of the development of and control over the effectiveness of treatment of cardiovascular illnesses
A diagnostic method for the prediction of the development and control of the effectiveness of the treatment of cardiovascular diseases, in which patient tissue samples are taken, microassay are... |
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US20140296106 |
METHODS FOR SCREENING SUBSTANCES CAPABLE OF MODULATING THE REPLICATION OF AN INFLUENZA VIRUS
The present invention relates to methods for screening substances capable of modulating the replication of an influenza virus. More particularly, the present invention relates to methods for... |
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US20120070459 |
METHOD FOR KEEPING A FOOT-AND-MOUTH DISEASE VACCINE AVAILABLE FOR EMERGENCY VACCINATION
The present invention pertains to a method for keeping a foot-and-mouth disease vaccine available for emergency vaccination of animals against foot-and-mouth disease, the vaccine comprising a... |
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US20110008765 |
USE OF THREE-DIMENSIONAL MICROFABRICATED TISSUE ENGINEERED SYSTEMS FOR PHARMACOLOGIC APPLICATIONS
The present invention generally relates to a combination of the fields of tissue engineering, drug discovery and drug development. It more specifically provides new methods and materials for... |
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US20140205620 |
ENGINEERED RESPIRATORY SYNCYTIAL VIRUSES WITH CONTROL OF CELL-TO-CELL VIRUS TRANSMISSION FOR ENHANCED SAFETY OF LIVE VIRUS VACCINES
Highly antigenic yet safe vaccines against diseases caused by Paramyxoviridae viruses such as respiratory syncytial virus (RSV) are provided. The vaccines comprise attenuated Paramyxoviridae... |
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US20140322164 |
METHOD OF ASSESSING RISK OF PML
The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML). |
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US20140335116 |
AVOIDING NARCOLEPSY RISK IN INFLUENZA VACCINES
The invention provides influenza vaccines and methods which improve the safety of influenza vaccines further, in particular in relation to the risk of causing narcolepsy in adjuvanted vaccines. |
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US20120219585 |
INFLUENZA TREATMENT AND/OR CHARACTERIZATION, HUMAN-ADAPTED HA POLYPEPTIDES; VACCINES
The present invention provides, among other things, methods, reagents, and systems for the treatment, detection, analysis, and/or characterization of influenza infections. |
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US20140050697 |
ANALYSIS OF HCV GENOTYPES
A method for predicting response of a patient infected with HCV-1a to interferon treatment. |
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US20140256735 |
METHOD FOR ASSESSING A LIVER OF A PATIENT HAVING A CHRONIC HEPATITIS B VIRUS INFECTION
The invention generally relates to method for assessing a liver of a patient having a chronic hepatitis B virus infection. In certain aspects, methods of the invention involve obtaining a sample... |
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US20140058000 |
DIAGNOSTIC MARKERS FOR DETERMINING THE PREDISPOSITION TO THE DEVELOPMENT OF CERVICAL CANCER AND OLIGONUCLEOTIDES USED FOR THE DETERMINATION
The present invention relates to a method for predisposition prediction of a subject to the development of cervical cancer and/or cancer precursors in an infection with the human papilloma virus... |
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US20120129705 |
DIAGNOSTIC MARKERS FOR DETERMINING THE PREDISPOSITION TO THE DEVELOPMENT OF CERVICAL CANCER AND OLIGONUCLEOTIDES USED FOR THE DETERMINATION
The present invention relates to a method for predisposition prediction of a subject to the development of cervical cancer and/or cancer precursors in an infection with the human papilloma virus... |
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US20110021611 |
EFFICIENT CELL CULTURE SYSTEM FOR HEPATITIS C VIRUS GENOTYPE 5A
The present inventors developed 5a/2a intergenotypic recombinants in which the JFH1 structural genes (Core, E1 and E2), p7 and all of or part of NS2 were replaced by the corresponding genes of the... |
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US20110086349 |
Proliferation Signatures and Prognosis for Gastrointestinal Cancer
This invention relates to methods and compositions for determining the prognosis of cancer in a patient, particularly for gastrointestinal cancer, such as gastric or colorectal cancer.... |
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US20130089854 |
KIT FOR DOT IMMUNOGOLD DIRECTED FILTRATION ASSAY AND USE THEREOF
A kit for dot immunogold directed filtration assay including a dot immunogold directed filtration card, a detection probe labeled by nano colloidal gold or latex beads, a negative standard, a... |
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US20140248604 |
METHOD FOR DETECTING HIV-1 CO-RECEPTOR TROPISM
A method for determining HIV-1 co-receptor tropism in an HIV-infected patient includes preparing an HIV-1 envelope protein coding sequence from a sample, introducing the HIV-1 envelope protein... |
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US20140308658 |
UTILITIES OF STIMULATED WHOLE BLOOD CULTURE SYSTEMS
The invention describes a method for determining how to stimulate, monitor and/or inhibit virus production in whole blood culture. The invention relates to a test kit for performing the method and... |
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US20130078613 |
Selection of HCV Treatment
The present invention is based on the discovery of an association between the SNP genotype at the rs12979860 locus in the IL28B gene promoter and the probability of achieving a SVR in HC... |
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US20150132343 |
SYSTEM AND METHOD FOR THE DETECTION AND TREATMENT OF INFECTION BY A MICROBIAL AGENT ASSOCIATED WITH HIV INFECTION
A method of treating a patient, comprising administering at least one antibiotic, e.g., doxycycline and ciprofloxacin, sufficient to substantially treat an intracellular bacterial organism present... |
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US20130034500 |
Cationic Steroid Antimicrobial Compositions and Methods of Use
The invention provides methods for decreasing or inhibiting herpesviridae (HV) infection or pathogenesis of a cell in vitro, ex vivo or in vivo, a symptom or pathology associated with a... |
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US20120315295 |
Development of a Marker Foot and Mouth Disease Virus Vaccine Candidate That is Attenuated in the Natural Host
We have generated novel molecularly marked FMDV A24LL3DYR and A24LL3BPVKV3DYR vaccine candidates. The mutant viruses contain a deletion of the leader coding region (LL) rendering the virus... |
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US20140322704 |
Hepatitis Virus Culture Systems Using Stem Cell-Derived Human Hepatocyte-Like Cells and Their Methods of Use
The invention relates to the discovery that DHH derived from stem cells are permissive for infection by hepatitis viruses (HV), such as hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis... |
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US20100330549 |
HETERODUPLEX TRACKING ASSAY
A change in viral tropism occurs in many HIV positive individuals over time and may be indicated by a shift in coreceptor use from CCR5 to CXCR4. The shift in coreceptor use to CXCR4 has been... |
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US20100323341 |
HETERODUPLEX TRACKING ASSAY
A change in viral tropism occurs in many HIV positive individuals over time and may be indicated by a shift in coreceptor use from CCR5 to CXCR4. The shift in coreceptor use to CXCR4 has been... |
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US20100323340 |
HETERODUPLEX TRACKING ASSAY
A change in viral tropism occurs in many HIV positive individuals over time and may be indicated by a shift in coreceptor use from CCR5 to CXCR4. The shift in coreceptor use to CXCR4 has been... |
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US20120129153 |
Diagnostic method for the prediction of the development and control of the effectiveness of the treatment of oncological illnesses
A diagnostic method, in which patient tissue samples are taken, microassay are prepared, specific anti-viral immunoglobulins are processed, the number of cells infected by two or more viruses... |
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US20150051096 |
LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS
Provided in certain embodiments are new methods for forming azido modified biomolecule conjugates of reporter molecules, carrier molecules or solid support. In other embodiments are provided... |
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US20100304360 |
GOLD NANOPARTICLE HPV GENOTYPING SYSTEM AND ASSAY
The invention provides oligonucleotides, kits and methods for genotyping HPV. |
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US20100322954 |
ENHANCED HIV-1 VACCINES AND METHODS FOR THEIR USE
The present invention provides peptides and proteins for use in second generation HIV vaccines and as diagnostic tools in the treatment and control of HIV infection. The antiviral protection shown... |
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US20150219656 |
METHODS FOR DETECTING HUMAN PAPILLOMAVIRUS AND PROVIDING PROGNOSIS FOR HEAD AND NECK SQUAMOUS CELL CARCINOMA
Methods and kits for diagnosing and determining prognosis of head and neck squamous cell carcinoma are described. |
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US20140037665 |
PESTIVIRUS SPECIES
The application relates to a pestivirus, designated PMC virus, that is associated with porcine myocarditis syndrome, and the gene and protein sequences derived therefrom. The application further... |
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US20120237519 |
PESTVIRUS SPECIES
The application relates to a pestivirus, designated PMC virus, that is associated with porcine myocarditis syndrome, and the gene and protein sequences derived therefrom. The application further... |
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US20150017630 |
SIGNATURES AND DETERMINANTS FOR DIAGNOSING INFECTIONS AND METHODS OF USE THEREOF
Antibiotics (Abx) are the world's most misused drugs. Antibiotics misuse occurs when the drug is administered in case of a non-bacterial infection (such as a viral infection) for which it is... |
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US20120107338 |
IDENTIFICATION OF A NOVEL RETROVIRUS IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA
Methods for producing an immune response to a benign prostatic hyperplasia (BPH) virus are disclosed herein. In several examples, the immune response is a protective immune response. In additional... |
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US20120157331 |
METHODS OF DETECTING SUSCEPTIBILITY TO LEUKEMIA/ LYMPHOMA AND INDUCTION OF LEUKEMIA AND LYMPHOMAS
A diagnostic test is described using aspergillus flavus fungal cultures, EBV or their combination to induce leukemic cell surface markers in mononuclear cells of former or current leukemia... |
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US20150225702 |
ADENO-ASSOCIATED VIRUS VIRIONS WITH VARIANT CAPSID AND METHODS OF USE THEREOF
The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells, when administered via... |
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US20140364338 |
Adeno-Associated Virus Virions with Variant Capsid and Methods of Use Thereof
The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells, when administered via... |
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US20140322237 |
NEURODEGENERATIVE DISEASES AND METHODS OF MODELING
Disclosed are embryonic stem cells and motor neurons derived from mice carrying transgenic alleles of the normal or mutant human SOD1 gene. Also disclosed are in vitro systems employing such SOD1... |