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US20140271542 GENETIC MARKER FOR PREDICTING PROGNOSIS IN PATIENTS INFECTED WITH HEPATITIS C VIRUS  
The present invention provides methods and materials for predicting the clinical outcome of a hepatitis C virus (HCV) infection. In particular, the invention relates to methods and materials for...
US20140141410 FELINE LEUKEMIA VIRUS TRANS-MEMBRANE PROTEIN P15E FOR DIAGNOSIS OF FELV INFECTION  
The invention provides for a method for the detection of FeLV infection in a patient, wherein a sample obtained from the patient is contacted in-vitro with a recombinant transmembrane p15E protein...
US20130287832 SOLUBLE NEEDLE ARRAYS FOR DELIVERY OF INFLUENZA VACCINES  
Influenza vaccines are administered using solid biodegradable microneedles. The microneedles are fabricated from the influenza vaccine in combination with solid excipient(s) and, after penetrating...
US20140271713 METHOD FOR KEEPING A FOOD AND MOUTH DISEASE VACCINE AVAILABLE FOR EMERGENCY VACCINATION  
The present invention pertains to a method for keeping a foot-and-mouth disease vaccine available for emergency vaccination of animals against foot-and-mouth disease, the vaccine comprising a...
US20130109010 METHOD FOR DETECTION OF INFECTION WITH HUMAN CYTOMEGALOVIRUS  
A novel means by which HCMV infection can be detected with a high sensitivity and whose practicality is high is disclosed. The present inventors synthesized as many as 15 kinds of HCMV proteins in...
US20140065600 METHOD OF EVALUATING ORAL CANCER RISK IN HUMAN  
A method of providing a risk evaluation and diagnosis of human oral cancer, by examining at the presence in human saliva sample of a combination of particulate nucleic acids from bacteria, virus,...
US20140329230 METHODS FOR DETECTING HUMAN PAPILLOMAVIRUS AND PROVIDING PROGNOSIS FOR HEAD AND NECK SQUAMOUS CELL CARCINOMA  
Methods and kits for diagnosing and determining prognosis of head and neck squamous cell carcinoma are described. An exemplary method for diagnosing head and neck squamous cell carcinoma (HNSCC)...
US20140134600 BIOMARKERS ASSOCIATED WITH DEVELOPMENT OF HEPATOCELLULAR CARCINOMA IN PATIENTS WITH HEPATITIS B VIRUS INFECTION, AND METHOD FOR DETECTION THEREOF  
The present invention is intended to provide a method for predicting risk of hepatocellular carcinoma (HCC) in hepatitis B virus (HBV)-infected patients with a high accuracy. More specifically,...
US20120282217 FOOT AND MOUTH DISEASE VIRUS (FMDV) CONSENSUS PROTEINS, CODING SEQUENCES THEREFOR AND VACCINES MADE THEREFROM  
Provided herein is a nucleic acid comprising consensus amino acid sequence of foot-and-mouth disease FMDV VP1-4 coat proteins of FMDV subtypes A, Asia 1, C, O, SAT1, SAT2, and SAT3 as well as...
US20150161359 METHODS FOR SAFETY TESTING  
The invention provides improved methods for the safety testing of compositions which comprise biological products produced in a host cell, such as vaccine antigens or recombinant proteins.
US20120021936 BIOMARKERS FOR DENGUE  
The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying dengue status in a patient. In particular, the biomarkers of this invention are...
US20140329792 SYNTHETIC CATALASE/SUPEROXIDE DISMUTASE MIMETICS AND METHODS FOR TREATING VIRAL INFECTIONS  
The invention provides for the treatment of disorders related to viral infection, using salen manganese compounds.
US20120129152 Diagnostic method for the prediction of the development of and control over the effectiveness of treatment of cardiovascular illnesses  
A diagnostic method for the prediction of the development and control of the effectiveness of the treatment of cardiovascular diseases, in which patient tissue samples are taken, microassay are...
US20140296106 METHODS FOR SCREENING SUBSTANCES CAPABLE OF MODULATING THE REPLICATION OF AN INFLUENZA VIRUS  
The present invention relates to methods for screening substances capable of modulating the replication of an influenza virus. More particularly, the present invention relates to methods for...
US20120070459 METHOD FOR KEEPING A FOOT-AND-MOUTH DISEASE VACCINE AVAILABLE FOR EMERGENCY VACCINATION  
The present invention pertains to a method for keeping a foot-and-mouth disease vaccine available for emergency vaccination of animals against foot-and-mouth disease, the vaccine comprising a...
US20110008765 USE OF THREE-DIMENSIONAL MICROFABRICATED TISSUE ENGINEERED SYSTEMS FOR PHARMACOLOGIC APPLICATIONS  
The present invention generally relates to a combination of the fields of tissue engineering, drug discovery and drug development. It more specifically provides new methods and materials for...
US20140205620 ENGINEERED RESPIRATORY SYNCYTIAL VIRUSES WITH CONTROL OF CELL-TO-CELL VIRUS TRANSMISSION FOR ENHANCED SAFETY OF LIVE VIRUS VACCINES  
Highly antigenic yet safe vaccines against diseases caused by Paramyxoviridae viruses such as respiratory syncytial virus (RSV) are provided. The vaccines comprise attenuated Paramyxoviridae...
US20140322164 METHOD OF ASSESSING RISK OF PML  
The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML).
US20140335116 AVOIDING NARCOLEPSY RISK IN INFLUENZA VACCINES  
The invention provides influenza vaccines and methods which improve the safety of influenza vaccines further, in particular in relation to the risk of causing narcolepsy in adjuvanted vaccines.
US20120219585 INFLUENZA TREATMENT AND/OR CHARACTERIZATION, HUMAN-ADAPTED HA POLYPEPTIDES; VACCINES  
The present invention provides, among other things, methods, reagents, and systems for the treatment, detection, analysis, and/or characterization of influenza infections.
US20140050697 ANALYSIS OF HCV GENOTYPES  
A method for predicting response of a patient infected with HCV-1a to interferon treatment.
US20140256735 METHOD FOR ASSESSING A LIVER OF A PATIENT HAVING A CHRONIC HEPATITIS B VIRUS INFECTION  
The invention generally relates to method for assessing a liver of a patient having a chronic hepatitis B virus infection. In certain aspects, methods of the invention involve obtaining a sample...
US20140058000 DIAGNOSTIC MARKERS FOR DETERMINING THE PREDISPOSITION TO THE DEVELOPMENT OF CERVICAL CANCER AND OLIGONUCLEOTIDES USED FOR THE DETERMINATION  
The present invention relates to a method for predisposition prediction of a subject to the development of cervical cancer and/or cancer precursors in an infection with the human papilloma virus...
US20120129705 DIAGNOSTIC MARKERS FOR DETERMINING THE PREDISPOSITION TO THE DEVELOPMENT OF CERVICAL CANCER AND OLIGONUCLEOTIDES USED FOR THE DETERMINATION  
The present invention relates to a method for predisposition prediction of a subject to the development of cervical cancer and/or cancer precursors in an infection with the human papilloma virus...
US20110021611 EFFICIENT CELL CULTURE SYSTEM FOR HEPATITIS C VIRUS GENOTYPE 5A  
The present inventors developed 5a/2a intergenotypic recombinants in which the JFH1 structural genes (Core, E1 and E2), p7 and all of or part of NS2 were replaced by the corresponding genes of the...
US20110086349 Proliferation Signatures and Prognosis for Gastrointestinal Cancer  
This invention relates to methods and compositions for determining the prognosis of cancer in a patient, particularly for gastrointestinal cancer, such as gastric or colorectal cancer....
US20130089854 KIT FOR DOT IMMUNOGOLD DIRECTED FILTRATION ASSAY AND USE THEREOF  
A kit for dot immunogold directed filtration assay including a dot immunogold directed filtration card, a detection probe labeled by nano colloidal gold or latex beads, a negative standard, a...
US20140248604 METHOD FOR DETECTING HIV-1 CO-RECEPTOR TROPISM  
A method for determining HIV-1 co-receptor tropism in an HIV-infected patient includes preparing an HIV-1 envelope protein coding sequence from a sample, introducing the HIV-1 envelope protein...
US20140308658 UTILITIES OF STIMULATED WHOLE BLOOD CULTURE SYSTEMS  
The invention describes a method for determining how to stimulate, monitor and/or inhibit virus production in whole blood culture. The invention relates to a test kit for performing the method and...
US20130078613 Selection of HCV Treatment  
The present invention is based on the discovery of an association between the SNP genotype at the rs12979860 locus in the IL28B gene promoter and the probability of achieving a SVR in HC...
US20150132343 SYSTEM AND METHOD FOR THE DETECTION AND TREATMENT OF INFECTION BY A MICROBIAL AGENT ASSOCIATED WITH HIV INFECTION  
A method of treating a patient, comprising administering at least one antibiotic, e.g., doxycycline and ciprofloxacin, sufficient to substantially treat an intracellular bacterial organism present...
US20130034500 Cationic Steroid Antimicrobial Compositions and Methods of Use  
The invention provides methods for decreasing or inhibiting herpesviridae (HV) infection or pathogenesis of a cell in vitro, ex vivo or in vivo, a symptom or pathology associated with a...
US20120315295 Development of a Marker Foot and Mouth Disease Virus Vaccine Candidate That is Attenuated in the Natural Host  
We have generated novel molecularly marked FMDV A24LL3DYR and A24LL3BPVKV3DYR vaccine candidates. The mutant viruses contain a deletion of the leader coding region (LL) rendering the virus...
US20140322704 Hepatitis Virus Culture Systems Using Stem Cell-Derived Human Hepatocyte-Like Cells and Their Methods of Use  
The invention relates to the discovery that DHH derived from stem cells are permissive for infection by hepatitis viruses (HV), such as hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis...
US20100330549 HETERODUPLEX TRACKING ASSAY  
A change in viral tropism occurs in many HIV positive individuals over time and may be indicated by a shift in coreceptor use from CCR5 to CXCR4. The shift in coreceptor use to CXCR4 has been...
US20100323341 HETERODUPLEX TRACKING ASSAY  
A change in viral tropism occurs in many HIV positive individuals over time and may be indicated by a shift in coreceptor use from CCR5 to CXCR4. The shift in coreceptor use to CXCR4 has been...
US20100323340 HETERODUPLEX TRACKING ASSAY  
A change in viral tropism occurs in many HIV positive individuals over time and may be indicated by a shift in coreceptor use from CCR5 to CXCR4. The shift in coreceptor use to CXCR4 has been...
US20120129153 Diagnostic method for the prediction of the development and control of the effectiveness of the treatment of oncological illnesses  
A diagnostic method, in which patient tissue samples are taken, microassay are prepared, specific anti-viral immunoglobulins are processed, the number of cells infected by two or more viruses...
US20150051096 LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS  
Provided in certain embodiments are new methods for forming azido modified biomolecule conjugates of reporter molecules, carrier molecules or solid support. In other embodiments are provided...
US20100304360 GOLD NANOPARTICLE HPV GENOTYPING SYSTEM AND ASSAY  
The invention provides oligonucleotides, kits and methods for genotyping HPV.
US20100322954 ENHANCED HIV-1 VACCINES AND METHODS FOR THEIR USE  
The present invention provides peptides and proteins for use in second generation HIV vaccines and as diagnostic tools in the treatment and control of HIV infection. The antiviral protection shown...
US20150219656 METHODS FOR DETECTING HUMAN PAPILLOMAVIRUS AND PROVIDING PROGNOSIS FOR HEAD AND NECK SQUAMOUS CELL CARCINOMA  
Methods and kits for diagnosing and determining prognosis of head and neck squamous cell carcinoma are described.
US20140037665 PESTIVIRUS SPECIES  
The application relates to a pestivirus, designated PMC virus, that is associated with porcine myocarditis syndrome, and the gene and protein sequences derived therefrom. The application further...
US20120237519 PESTVIRUS SPECIES  
The application relates to a pestivirus, designated PMC virus, that is associated with porcine myocarditis syndrome, and the gene and protein sequences derived therefrom. The application further...
US20150017630 SIGNATURES AND DETERMINANTS FOR DIAGNOSING INFECTIONS AND METHODS OF USE THEREOF  
Antibiotics (Abx) are the world's most misused drugs. Antibiotics misuse occurs when the drug is administered in case of a non-bacterial infection (such as a viral infection) for which it is...
US20120107338 IDENTIFICATION OF A NOVEL RETROVIRUS IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA  
Methods for producing an immune response to a benign prostatic hyperplasia (BPH) virus are disclosed herein. In several examples, the immune response is a protective immune response. In additional...
US20120157331 METHODS OF DETECTING SUSCEPTIBILITY TO LEUKEMIA/ LYMPHOMA AND INDUCTION OF LEUKEMIA AND LYMPHOMAS  
A diagnostic test is described using aspergillus flavus fungal cultures, EBV or their combination to induce leukemic cell surface markers in mononuclear cells of former or current leukemia...
US20150225702 ADENO-ASSOCIATED VIRUS VIRIONS WITH VARIANT CAPSID AND METHODS OF USE THEREOF  
The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells, when administered via...
US20140364338 Adeno-Associated Virus Virions with Variant Capsid and Methods of Use Thereof  
The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells, when administered via...
US20140322237 NEURODEGENERATIVE DISEASES AND METHODS OF MODELING  
Disclosed are embryonic stem cells and motor neurons derived from mice carrying transgenic alleles of the normal or mutant human SOD1 gene. Also disclosed are in vitro systems employing such SOD1...