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US20110207113 |
PROTEIN STRUCTURE AND METHOD OF USING PROTEIN STRUCTURE
Methods for building an atomic model of a protein molecule that include: (a) identifying a protein molecule with at least 20% sequence identity to Microsomal Prostaglandin E Synthase 1 (MPGES1)... |
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US20130184173 |
BIOMARKERS FOR MULTIPLE SCLEROSIS
Biomarkers that can be used for the diagnosis and prognosis of multiple sclerosis in pediatric patients presenting with clinically isolated syndrome or acquired demyelination syndrome are described. |
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US20150204882 |
METHIONINE METABOLITES PREDICT AGGRESSIVE CANCER PROGRESSION
The invention relates to the use of enzymes, nanorods, and nanoelectronic devices to detect cysteine level in a patient sample and relates to the use of the detected cysteine level to predict... |
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US20110212464 |
PACAP AS A MARKER FOR CANCER
The present invention relates to a method aiding in the assessment of cancer. It discloses the use of the proapoptotic caspase adaptor protein (=PACAP) as a universal marker of different types of... |
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US20120070826 |
LAFORA'S DISEASE GENE
A novel gene (EPM2B) that is mutated in humans and dogs with Lafora's disease is described. |
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US20110086831 |
PROCALCITONIN FOR THE DIAGNOSIS OF BACTERIAL INFECTIONS AND GUIDANCE OF ANTIBIOTIC TREATMENT IN PATIENTS WITH ACUTE STROKE OR TRANSIENT ISCHEMIC ATTACK
The present invention relates to an in vitro method for the diagnosis and treatment guidance of a bacterial infection in patients suffering from an acute ischemic or hemorrhagic stroke, comprising... |
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US20120088225 |
Method of Detecting Major In-Hospital Ischemic Complications and Predicting Length of Stay at an Intensive Care Unit
Methods of detecting major ischemic complications in critically ill patients comprise a) determining the blood concentration of glycerol at least once per hour; b) comparing the obtained blood... |
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US20100312139 |
Method for Identifying Mammals at Risk for Elevated intracranial Pressure
Disclosed are methods of diagnosing, screening and treating individuals at risk of elevated intracranial pressure based on detecting a transient decrease in serum ceruloplasmin and/or serum copper... |
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US20130078660 |
METHODS AND COMPOSITIONS FOR DETECTING PROTEIN MODIFICATIONS
Methods and compositions for detecting a protein modification in vitro and in vivo are disclosed. In certain embodiments, the protein modification detected is phosphorylation. |
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US20100317040 |
METHODS AND KITS FOR DIAGNOSING CANCER
A method of diagnosing oral cancer or oral pharyngeal cancer in a subject in need thereof is provided. The method comprising determining a level or activity of at least one marker in a saliva... |
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US20110230372 |
GENE EXPRESSION CLASSIFIERS FOR RELAPSE FREE SURVIVAL AND MINIMAL RESIDUAL DISEASE IMPROVE RISK CLASSIFICATION AND OUTCOME PREDICTION IN PEDIATRIC B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA
The present invention relates to the identification of genetic markers patients with leukemia, especially including acute lymphoblastic leukemia (ALL) at high risk for relapse, especially high... |
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US20100331833 |
IN-VITRO DEVICE MONITORING DURING MINIMALLY INVASIVE ABLATION THERAPY
A method and apparatus for monitoring and controlling interventional therapy is described, where the interventional therapy results in the destruction of tissue and the release of chemical... |
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US20120094900 |
SENSITIZING AGENTS FOR CANCER THERAPY, METHODS OF USE AND METHODS FOR THE IDENTIFICATION THEREOF
There is provided herein methods, compounds and methods for identifying compounds, for sensitizing a subject with cancer to a cancer therapy by inhibiting or down-regulating UROD. |
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US20110064747 |
METHODS FOR TREATMENT OF A SARCOMA USING AN EPIMETABOLIC SHIFTER (COENZYME Q10)
Methods and formulations for treating a sarcoma in humans using an epimetabolic shifter, such as Coenzyme Q10, a building block of CoQ10, a derivative of CoQ10, an analog of CoQ10, a metabolite of... |
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US20100319424 |
SYSTEMS AND PROCESSES FOR PRODUCING BIOFUELS FROM BIOMASS
Systems and processes for converting bulky lignocellulosic biomass to high density biomass products, including biofuels, are described. The systems and processes relate to treating freshly... |
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US20130078645 |
BIOMARKERS
The invention relates to a method of diagnosing or monitoring schizophrenia or other psychotic disorder. The biomarkers used are selected from cyclophilin A, cytosalic non-specific dipepditase,... |
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US20130296175 |
Genetic Variants as Markers for Use in Urinary Bladder Cancer Risk Assessment, Diagnosis, Prognosis and Treatment
Polymorphic variants that have been found to be associated with risk of urinary bladder cancer are provided herein. Such polymorphic markers are useful for diagnostic purposes, such as in methods... |
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US20110236877 |
BIOSENSOR AND METHOD USING THE SAME TO PERFORM A BIOTEST
The present invention discloses a biosensor and a method using the same to perform a biotest. The biosensor of the present invention integrates a SAW (Surface Acoustic Wave) device and a test... |
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US20130149250 |
HYPERPOLARIZED AGENTS FOR MRI CHARACTERIZATION OF REDOX SYSTEMS IN VIVO
The present invention provides a MRI probe of use in detecting and characterizing redox systems in vivo. Also provided are methods of using the probe in MR imaging experiments for diagnosis of... |
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US20090029345 |
MODULATING SKELETAL MUSCLE
Methods of identifying skeletal muscle activators are provided. Methods of activating skeletal muscle using skeletal muscle activators are also provided. |
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US20100322949 |
METHODS FOR DIAGNOSING AND TREATING ASTROCYTOMAS
The invention relates to the identification of astrocytoma markers, astrocytoma stem cells and markers of such stem cells, and diagnostic, prognostic and therapeutic methods based on an... |
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US20110281287 |
SIZE SELF-LIMITING COMPOSITIONS AND TEST DEVICES FOR MEASURING ANALYTES IN BIOLOGICAL FLUIDS
A test strip or electrochemical sensor for measuring the amount of an analyte in a biological fluid, e.g. the glucose content of whole blood, includes a size self-limiting reagent formulation... |
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US20110053137 |
METHODS OF MODULATING COLD SENSORY PERCEPTION
The present invention relates to regulation of cold sensation and pain. More particularly, the present invention is directed to nucleic acids encoding a member of the transient regulatory protein... |
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US20110218120 |
ORDERED TWO- AND THREE-DIMENSIONAL STRUCTURES OF AMPHIPHILIC MOLECULES
The invention pertains, at least in part, to a method for forming an ordered structure of amphiphilic molecules, such as proteins. The method includes contacting a population of amphiphilic... |
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US20120202188 |
SERUM-BASED BIOMARKERS OF PANCREATIC CANCER AND USES THEREOF FOR DISEASE DETECTION AND DIAGNOSIS
Biomarkers of pancreatic cancer are described, as well as methods using these compounds for detecting pancreatic cancer. The methods can be used to diagnose a patient's health state, or change in... |
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US20150010934 |
METHODS FOR DETECTING RISK OF FATAL PROSTATE CANCER USING SERUM CALCIUM
A method of screening for increased risk of fatal prostate cancer in a subject comprises providing a blood sample collected from the subject, and then detecting the presence or absence of an... |
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US20110045520 |
FATTY ACID MARKERS FOR THE DIAGNOSIS, PROGNOSIS AND MANAGEMENT OF CARDIOVASCULAR DISEASE
Methods of detecting myocardial infarction are disclosed based on elevated levels of one or more free fatty acids. The methods may comprise detection of elevated levels of total free fatty acids... |
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US20100304357 |
UNIVERSAL DRINKING ADAPTER FOR BEVERAGE BOTTLES, AND DEVICES AND KITS FOR DETERMINING SMALL MOLECULES, METAL IONS, ENDOTOXINS, AND BACTERIA, AND METHODS OF USE THEREOF
Certain features, aspects, examples and embodiments described herein relate to adapters for securing drinking apparatuses for individuals of all ages (infants, children, adults, and seniors) such... |
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US20150064732 |
Analytical Test Cartridge; and, Methods
An analytical test cartridge is provided. The analytical test cartridge can be used for medical analyses of liquid samples removed from a patient, for example blood. The analytical test cartridge... |
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US20110195404 |
SYSTEMS AND METHODS FOR DETERMINING CALCIUM LEVELS
Systems and methods for determining calcium levels. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially... |
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US20110265197 |
Signatures and PCDeterminants Associated with Prostate Cancer and Methods of Use Thereof
The present invention provides methods of detecting cancer using biomarkers. |
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US20130309655 |
Capillary Electrophoresis Method for Fine Structural Analysis of Enoxaparin Sodium
A capillary electrophoresis method for quantitatively analyzing characteristic oligosaccharide present in enoxaparin sodium is provided in this invention. The method may be used for quantitatively... |
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US20130061339 |
METHOD OF DIAGNOSING TRICHOTILLOMANIA AND SIMILAR DISORDERS IN HUMANS AND RODENTS
The present disclosure provides a method of diagnosing neurological disorders including for example, impulse control disorders, such as barbering and trichotillomania using biomarkers such as... |
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US20110305640 |
METHOD TO TREAT PSORIASIS AND OTHER HYPERPROLIFERATIVE SKIN DISORDERS
Soluble adenylyl cyclase (sAC) is implicated in proliferation of keratinocytes. Inhibitors of sAC are useful for the treatment and/or prevention of psoriasis and other hyperproliferative skin... |
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US20110212459 |
NOVEL PRESENILIN ASSOCIATED MEMBRANE PROTEIN (PAMP) AND USES THEREOF
Presenilin Associated Membrane Protein (PAMP), and nucleic acids encoding this protein, are provided. PAMP and PAMP nucleic acids provide diagnostic and therapeutic tools for evaluating and... |
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US20150166562 |
METHODS AND PRODUCTS RELATED TO PROTOZOAN DISEASE
The invention relates to methods and related products for treatment or protozoan disease. The invention also relates to new compositions of matter useful in the treatment of protozoan disease and... |
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US20150126580 |
METHODS FOR DIAGNOSING AND TREATING ONCOGENIC KRAS-ASSOCIATED CANCER
Methods for diagnosing and treating cancer associated with an oncogenic Kras mutation in a subject are provided. |
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US20110195440 |
SYSTEMS AND METHODS FOR IDENTIFYING ALLERGIES
Systems and methods for identifying allergies. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially... |
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US20080085506 |
Automated, field-portable system for conducting toxicity measurements in water, soils, and sediments
A system for testing the toxicity of a test sample comprising: an aqueous suspension of dinoflagellates; a test chamber configured to contain the aqueous suspension of dinoflagellates and the test... |
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US20070059678 |
Breast milk contaminant detection device
A breast milk detection device includes a plurality of test strips slidably and removably coupled to a test housing. Each test strip is connected to an absorbent section so that a breast milk... |
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US20150175998 |
Methods and Kits to Create Protein Substrate˜HECT-Ubiquitin Ligase Pairs
Methods and kits to use in the isolation and identification of crosslinked protein substrate ubiquitin ligase complexes are disclosed. More specifically the methods and kits disclosed herein... |
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US20130210045 |
BIOMARKER FOR FATIGUE, AND USE THEREOF
Ratios of measured values of glucose, citrate, and cis-aconitate in a biological sample obtained from a subject to measured values of glucose, citrate, and cis-aconitate in a biological sample... |
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US20130090597 |
USE OF MODIFIED HOLLOW FIBER MATERIALS FOR REMOVING EXOTOXINS PRODUCED BY ESCHERICHIA COLI FROM LIQUIDS AND METHODS FOR TREATING CONCOMITANT DISEASES
The present invention relates to chemically modified hollow fiber materials for extracorporeally removing exotoxins produced by pathogenic Escherichia coli from protein containing liquids,... |
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US20110046351 |
MUTANT PROTEINS AND METHODS FOR SELECTING THEM
A method for selecting a membrane protein with increased stability, the method comprising: a) providing one or more mutants of a parent membrane protein in a membrane-containing composition,... |
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US20110217720 |
Compositions and Kits Pertaining to Analyte Determination
This invention pertains to methods, kits and/or compositions for the determination of analytes by mass analysis using unique labeling reagents or sets of unique labeling reagents. The labeling... |
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US20150203892 |
METHOD FOR DETERMINING BREAST CANCER
The present invention relates to: a breast cancer marker which is selected from the group consisting of carboxypeptidase N subunit 2, extracellular matrix protein 1, serum amyloid P component,... |
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US20110020784 |
RED FLUORESCENT PROTEINS WITH ENHANCED BACTERIAL EXPRESSION, INCREASED BRIGHTNESS AND REDUCED AGGREGATION
Polynucleotides encoding variant polypeptides of DsRed are provided herein. The DsRed variants have increased bacterial expression, reduced aggregation, increased solubility, shifted emission... |
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US20120015383 |
NOVEL DIAGNOSTIC MARKER FOR TYPE 1 DIABETES MELLITUS
The present invention provides, as a novel diagnosis marker for type 1 diabetes mellitus, a type 1 diabetes mellitus diagnostic composition comprising alanyl-tRNA synthetase, glycyl-tRNA... |
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US20080044842 |
Biological Test Strip
A test sensor (10) for use in the determination of an analyte in a liquid sample. The test sensor (10) includes a base (14), a lid (12), and a test membrane (18) adhered to the base. A reagent... |
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US20120028241 |
Assay System for Monitoring the Effects of Genetically Engineered Cells to Alter Function of a Synctium
This invention provides methods for determining the ability of a gene construct to alter the rhythm and contractility of a syncytial cell. Furthermore, this invention provides methods for... |