Sign up


Match Document Document Title
US20120108464 TEST SYSTEMS, METHODS AND USES INVOLVING AS160 PROTEIN  
The present invention relates to a method of identifying a substance altering glucose uptake and/or GLUT4 translocation to the plasma membrane of a cell comprising contacting a test system...
US20130089526 Methods for Using Synthetic Triterpenoids in the Treatment of Bone or Cartilage Diseases or Conditions  
The present invention features the use of a synthetic triterpenoid to induce gene expression and differentiation of stem or progenitor cells in the treatment of bone/cartilage diseases or conditions.
US20140017784 Methods for Expansion and Analysis of Cultured Hematopoietic Stem Cells  
Methods and kits for propagating hematopoietic stem cells are provided. The methods comprise culturing cells in medium comprising one or more angiopoietin-like proteins, under conditions sufficient...
US20110196343 Methods for Expansion and Analysis of Cultured Hematopoietic Stem Cells  
Methods and kits for propagating hematopoietic stem cells are provided. The methods comprise culturing cells in medium comprising one or more angiopoietin-like proteins, under conditions sufficient...
US20120003738 Method For Amplification And Functional Enhancment Of Blood Derived Progenitor Cells Using A Closed Culture System  
The present invention provides a method for expanding and improving functional capacity of human adult-derived progenitor cells in vitro using a closed culture system. The present invention...
US20080274092 Erythrocytes Containing Arginine Deiminase  
Use of erythrocytes containing arginine deirainase for the preparation of a medicinal product for lowering the plasma concentration of arginine in vivo. Said use relates in particular to the...
US20120148553 METHODS OF GENERATING NATURAL KILLER CELLS  
Provided herein are methods of producing natural killer cells using a two-step expansion and differentiation method. Also provided herein are methods of suppressing tumor cell proliferation, of...
US20110117061 Ex Vivo Expansion of Human Hematopoietic Stem Cells  
Methods and kits for expanding the number of hematopoietic stem cells are provided. The methods comprise incubating cells in medium comprising isolated IGFBP-2 and an angiopoietin-like protein...
US20100304483 T-CELL VACCINATION IN THE TREATMENT OF HIV INFECTION  
A method for the preparation of a T cell vaccine for the treatment of immunodeficient HIV-infected patients is described herein, based on the enrichment of autologous CD4-reactive CD8 T cells. Also...
US20120003254 Breast Cancer Vaccine  
Compositions and methods for immunization against human breast cancer are disclosed. A breast cancer vaccine comprises an immunogenic polypeptide comprising human α-lactalbumin.
US20110182937 Dendritic Cell Vaccines  
Compositions and methods for the prophylaxis and treatment of human immunodeficiency virus (HIV) infections are disclosed herein. More specifically the present invention discloses describes an...
US20130236964 METHODS, NUCLEIC ACID CONSTRUCTS AND CELLS FOR TREATING NEURODEGENERATIVE DISORDERS  
A method of treating a neurodegenerative disorder is provided. The method is effected by administering to an individual in need thereof cells capable of exogenously regulatable neurotransmitter...
US20130064859 COMBINATORIAL VITAMIN D AND PROBIOTIC THERAPY FOR INFLAMMATORY BOWEL DISEASE  
A method of increasing the percentage of mouse and human Tregs is provided comprising providing B.fragilis or PSA and vitamin D or vitamin D metabolite to said mouse or human. Also, a method for...
US20110212541 COMPOSITIONS AND METHODS TO PROTECT CELLS BY BLOCKING ENTRY OF PATHOGEN PROTEINS  
Pathogenic effector proteins include one or more virulence motifs of amino acid consensus sequence BXZ, where B=RK or H; X=any amino acid or is absent; Z=L, M, I, W, Y or F) which bind to target...
US20100310532 GENE TARGETS IN ANTI-AGING THERAPY AND TISSUE REPAIR  
Novel gene and protein targets are described for treatment of cardiac disorders, anti-aging therapies and tissue repair. Identified biomarkers are prognostic of long term survival of patients...
US20070184030 Large scale storage of viable somatic stem and/or progenitor cells  
A large scale storage system of viable somatic stem and/or progenitor cells for use in a method of treatment of a disease or a disorder of a patient is described. The storage system includes a...
US20110268709 Generation of Histocompatible Tissues Using Nuclear Transplantation  
Tissues produced by culture of cells produced by nuclear transfer on a matrix derived from nuclear transfer embryos or embryos and pluripotent cells provided by other methods are provided. These...
US20120220032 OPTIMIZING CULTURE MEDIUM FOR CD34<+> HEMATOPOIETIC CELL EXPANSION  
The present invention provides a method of determining the optimal composition of a serum-free, eukaryotic cell culture medium supplement, using 2-level factorial design and the steepest ascent...
US20110065131 ASSAYS FOR MUTAGENESIS DETECTION  
The disclosure provides methods, systems, and kits for assaying an agent for mutagenic properties. The methods systems and kits utilize a DEL selectable marker and a colorimetric detection systems....
US20130196939 DETECTION OF DNA SEQUENCES AS RISK FACTORS FOR HIV INFECTION  
A method for identifying a risk factor for diseases, disorders or conditions, such as those caused by human immunodeficiency virus, using the polymerase chain reaction and specific primers. Methods...
US20140023723 Decellularized Extracellular Matrix  
Methods for producing compositions of decellularized extracellular matrix (DM) tissue culture are described. The compositions can be used for coating supports such as tissue culture substrates,...
US20110182950 COMBINATION OF BLOOD AND OF BIPHASIC CALCIUM PHOSPHATE CERAMIC PARTICLES  
The invention relates to a biomaterial containing coagulated blood or coagulated bone marrow aspirate and biphasic calcium phosphate ceramic particles, to a production method thereof and to the use...
US20110318318 ANTI-APOPTOTIC FUSION PROTEINS  
The present invention relates to a fusion protein comprising a protein transduction domain capable of introducing the fusion protein into a mammalian cell and an anti-apoptotic protein comprising...
US20140079678 Method for Activating Natural Killer Cells by Tumor Cell Preparation In Vitro  
The present invention provides a method for activating a Natural Killer (NK) cell by contacting the NK cell in vitro with an activating tumour cell preparation (ATCP). The invention also provides...
US20120328587 Method for Activating Natural Killer Cells by Tumor Cell Preparation In Vitro  
The present invention provides a method for activating a Natural Killer (NK) cell by contacting the NK cell in vitro with an activating tumour cell preparation (ATCP). The invention also provides...
US20110104131 HEMATOPOIETIC STEM CELLS AND METHODS OF TREATMENT OF NEOVASCULAR EYE DISEASES THEREWITH  
Isolated, mammalian, adult bone marrow-derived, lineage negative hematopoietic stem cell populations (Lin− HSCs) contain endothelial progenitor cells (EPCs) capable of rescuing retinal blood v...
US20110318264 METHODS AND COMPOSITIONS FOR DIAGNOSIS AND TREATMENT OF CANCER  
The present invention relates to the identification of nucleic acid and amino acid sequences that are characteristic of colorectal, in particular colonic, and gastric tumor tissues and colorectal,...
US20140011276 Formulation for Cultivating Dendritic Killer Cells and Method Using the Same  
A formulation and method for cultivating dendritic killer cells is disclosed in the present invention. The formulation comprises an effective amount of at least one cytokine and the abovementioned...
US20100297090 HEMATOPOIETIC CELL CULTURE NUTRIENT SUPPLEMENT  
The present invention provides a serum-free supplement which supports the growth of hematopoietic cells in culture. Also provided are a medium comprising a basal medium supplemented with the...
US20120252060 Self-Renewing Single Human Hematopoietic Stem Cells, an Early Lymphoid Progenitor and Methods of Enriching the Same  
This invention relates to human hematopoietic stem cells. Specifically the invention relations to the identification of single human hematopoietic stem cells capable of long-term multilineage...
US20120315338 LARGE SCALE GENERATION OF FUNCTIONAL MEGAKARYOCYTES AND PLATELETS FROM HUMAN EMBRYONIC STEM CELLS UNDER STROMAL-FREE CONDITIONS  
The present invention provides a method of generating megakaryocytes and platelets. In various embodiments, method involves the use of human embryonic stem cell derived hemangioblasts for...
US20130028915 DENDRITIC CELL (DC)-VACCINE THERAPY FOR PANCREATIC CANCER  
Compositions and methods for eliciting therapeutic immunity and improving clinical outcomes in patients with pancreatic cancer are disclosed herein. The present invention describes a dendritic cell...
US20130203164 Human Secreted Proteins  
The present invention relates to human secreted polypeptides, and isolated nucleic acid molecules encoding said polypeptides, useful for diagnosing and treating diseases, disorders, and/or...
US20110093020 Poly-porous hollow screw for target delivery of growth factors and stem cells:the design and potential clinical application  
Present invention depicts a poly-porous (micropore) hollow screws as diffusion chamber filled with core matrix for targeted delivery of growth factors and bone marrow stem cells. The screws...
US20110300144 METHODS AND COMPOSITIONS FOR DIAGNOSIS AND TREATMENT OF CANCER  
The present invention relates to the identification of nucleic acid and amino acid sequences that are characteristic of tumor tissues such as ovarian tumor and lung tumor tissues and which...
US20130058903 Stem-Cell Material and Method of Use  
Provided herein are mesenchymal stem cells which have been modified by the introduction of polynucleotides encoding for a mammalian Cdk1 protein. These cells do not sense in culture and are...
US20120329709 PRODUCTION OF GLYCOPROTEINS  
The present invention provides methods and materials by which glycosylation of glycoproteins can be regulated. Methods include the monitoring and regulation of parameters such that a glycoprotein...
US20120282694 Methods for the Isolation and Expansion of Cord Blood Derived T Regulatory Cells  
The present invention encompasses methods, and kits for the isolation and expansion of T regulatory cells having the CD45RA+ phenotype, including such cells from human umbilical cord blood.
US20140037606 CELL-BASED, ANTI-CANCER VACCINES  
The present invention relates to cancer vaccines and more particularly to compositions and methods for producing activated antigen presenting cells (dendritic cells, macrophages, monocytes, or...
US20120252117 OPTIMIZED MESSENGER RNA  
The present invention is directed to a synthetic nucleic acid sequence which encodes a protein wherein at least one non-common codon or less-common codon is replaced by a common codon. The...
US20120148530 Method for the treatment or prevention of virus infection using polybiguanide-based compounds  
An inexpensive, easily available, and convenient method of treating or preventing a virus infection is provided. The present invention relates to a method for the treatment or prevention of virus...
US20130244889 CONSTRUCT FOR PROMOTING ABSORPTION OF MOLECULES BY A CELL AND METHODS OF USING THE CONSTRUCT  
The present invention is directed to a construct for promoting absorption of molecules by a cell and the application thereof in drug and gene delivery. The present invention further describes...
US20130287751 METHOD FOR DEVELOPING NATURAL KILLER CELLS FROM STEM CELLS  
A method for producing NK cells from pluripotent stem cells, which includes culturing pluripotent stem cells in a first serum-free medium, aggregating the undifferentiated stem cells to form...
US20120070430 IDENTIFICATION OF TUMOR-ASSOCIATED MARKERS FOR DIAGNOSIS AND THERAPY  
The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic...
US20110052728 BOTANICAL EXTRACT FROM THE AQUEOUS STREAM OF THE PALM OIL MILLING PROCESS FOR THE PREVENTION AND INHIBITION OF OXIDATIVE STRESS AND HAEMOLYSIS IN HUMAN RED BLOOD CELLS  
The invention provides a composition for the prevention and inhibition of oxidative stress and haemolysis in human red blood cell wherein said composition compounds obtained from the aqueous stream...
US20140186310 METHOD OF EX VIVO CELLULAR GROWTH  
The present invention relates generally to an ex vivo method of producing a population of cells and materials for use therewith. More particularly, the present invention is directed to an ex vivo...
US20110045589 Methods Of Controlling Proliferation And Differentiation Of Stem And Progenitor Cells  
A method of ex-vivo expanding a population of stem cells, while at the same time inhibiting differentiation of the stem cells. The method comprises ex-vivo providing the stem cells with conditions...
US20110312543 Expression Vectors Based on Modified Ribosomal Protein Promoters and Uses Thereof in Post-Transcriptional Assessment  
The present invention relates to expression vector comprising (a) a promoter region comprising a non-inducible constitutively active ribosomal protein gene promoter, (b) an operably linked reporter...
US20130052728 COMPOSITIONS AND METHODS FOR MAKING AND USING BONE MARROW MESENCHYMAL STEM CELLS AND ERYTHROID PROGENITOR CELLS  
The invention provides compositions for making erythroid progenitor cells that comprise in vitro-activated bone marrow mesenchymal stem cells and embryoid bodies (EBs) or pluripotent stem cells,...
US20110306127 ENHANCING IRON UPTAKE IN PROTEIN-FREE MEDIA  
Methods for enhancing iron uptake in cell culture are described. The methods include using a NTBI uptake activator and non-protein bound iron source. Suitable NTBI activators are delineated. Also...