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US20090269830 |
Culture System and Method for Propagation of Human Blastocyst-Derived Stem Cells
The present invention relates to a culture system for and a method for propagation of human blastocyst-derived stem cells (hBS cells) upon enzymatic dissociation into a single cell suspension. The...
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US20090253151 |
Self-Renewing Master Adult Pluripotent Stem Cells
The present invention relates to a method for obtaining master adult pluripotent stem (MAPS) cells from adult human corneal epithelial tissues. The MAPS cells are obtained on the basis of...
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US20090239254 |
Functional pigmented skin equivalent
An in vitro skin equivalent includes at least one epidermis equivalent and at least one dermis equivalent, and further includes melanocytes constitutively producing melanin and fibroblasts.
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US20090232778 |
Methods and Compositions for Hair Growth
Methods and compositions for identifying and isolating dermal papilla cells are described. DP cells can be identified based on corin expression. Isolated DP cells can be used, e.g., to modulate...
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US20090220959 |
MARKERS OF DEFINITIVE ENDODERM
Disclosed herein are reagent-cell complexes comprising one or more definitive endoderm cells. Also described herein are compositions for detecting definitive endoderm. Method of enriching,...
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US20090208467 |
P27 AND P21 IN GENE THERAPIES
The expansion of a population of stem cells or progenitor cells, or precursors thereof, may be accomplished by disrupting or inhibiting p21 cip1/waf1 and/or p27, cyclin dependent kinase...
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US20090202616 |
Composite, Method of Producing the Composite and Uses of the Same
The invention relates to a composite comprising a semi-permeable barrier layer that is permeable to oxygen and impermeable to moisture; and a scaffold fiber layer formed by electrospinning fibers...
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US20090191163 |
Primed tissue for tissue engineering and methods of priming tissue
Provided is a composition comprising a primed engineered tissue construct, methods of making the composition, methods of using the composition in dermatologic surgery, and a kit for supplying...
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US20090186407 |
Alternative Compositions and Methods for the Culture of Stem Cells
Methods and cell culture medium for the generation and maintenance of human pluripotent embryonic stem cells are disclosed. Human embryonic stem cells are cultured with human feeder cell...
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US20090145087 |
COLD STORAGE OF ORGANOTYPICALLY CULTURED SKIN EQUIVALENTS FOR CLINICAL APPLICATIONS
The present invention relates generally to systems and methods for storing, shipping and using skin equivalents made by organotypic culture. In particular, the present invention relates to systems...
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US20090142841 |
Vectors capable of immortalizing non-dividing cells and cells immortalized with said vectors
Vectors capable of stably integrating a transgene in the genome of a non-dividing cell or of a slowly-dividing cell, said vector comprising or expressing at least one immortalization molecule and...
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US20090130065 |
Multipotent adult stem cells
Isolated human multipotent adult stem cell and isolated populations of cells that include human multipotent adult stem cells are disclosed. Human hair-follicle derived multipotent adult stem cells...
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US20090068154 |
Cell Composition for Transplant
The present invention provides a cell composition for transplant comprising fibroblasts originating in buccal fat pad.
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US20090028795 |
NOD1 as an Anti-Tumor Agent
The invention provides compositions and methods for treating tumors that involve increasing the expression of Nod1 and/or the activity of NOD1.
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US20080311625 |
Immortal Pluripotent Stem Cell Line, Cell Lines Derived Therefrom, Methods of Preparing Thereof and Their Uses
The present invention relates to immortal pluripotent stem cells derived from a human leukaemia cell line, preferably a human monocytoid cell line and more preferably the human monocytoid cell...
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US20080311552 |
Use of Sirnas in Organ Storage/Reperfusion Solutions
The invention is the modification of organs, tissues and cells with a storage/reperfusion solution comprising siRNAs specific for genes whose expression is associated with loss of viability or cell...
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US20080279830 |
SPONGY EPITHELIAL CELL SCAFFOLD FOR VASCULARIZING WOUNDS
The present invention provides isolated apoptotic epithelial scaffolds. The scaffolds find use in promoting re-vascularization of wounded tissues. The present invention also provides isolated or ex...
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US20080261259 |
Culture Media For Expansion and Differentiation of Epidermal Cells and Uses Thereof For In Vitro Growth of Hair Follicles
The invention is directed to a chemically defined animal cell culture media, and methods for preparing such a medium, wherein the media are suitable for culturing epidermal cells, preferably human...
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US20080261244 |
Compositions And Methods For Treating And Diagnosing Pancreatic Cancer
The present invention relates to the field of oncology and provides novel compositions and methods for diagnosing and treating pancreatic cancer. In particular, the present invention provides...
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US20080241126 |
Nucleic acids encoding Human Engineered heavy and light chain variable region sequences to Ep-CAM
Human engineered anti-Ep-CAM antibodies and various uses therefore are disclosed. These human engineered anti-Ep-CAM antibodies have high affinity binding to Ep-CAM with low immunogenicity.
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US20080226611 |
Gene Therapy Using TGF-beta
The subject invention is related to a cell-mediated gene therapy treatment for orthopedic disease using a member belonging to the transforming growth factor-β (TGF-β) superfamily. TGF-β gene...
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US20080199399 |
Interfacing Nanostructures to Biological Cells
Disclosed herein are methods and materials by which nanostructures such as carbon nanotubes, nanorods, etc. are bound to lectins and/or polysaccharides and prepared for administration to cells....
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US20080193420 |
Method for the Production of a Cell Composition Containing Epithelial Cells
Disclosed is a method for forming epithelial cells. Said method comprises the steps of aggregating stem cells from differentiated exocrine gland tissue to obtain an organoid body and...
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US20080188379 |
PTU COMPOUNDS FOR PROMOTING THE IN VITRO CULTURE OF (HIGHLY PIGMENTED) MELANOCYTES
A method for promoting the in vitro multiplication of human melanocytes and/or the freezing thereof, notably human melanocytes obtained from individuals of phototype IV, V or VI or from...
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US20080160589 |
Gene Rcs 24
The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also...
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US20080124734 |
Stable Cell Lines and Methods for Evaluating Gastrointestinal Absorption of Chemicals
Nucleic acids and vectors for interfering with the expression of membrane efflux transport proteins in cells that express such proteins are provided. Also provided are cells and cell lines...
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US20080108134 |
Bioengineered Tissue Constructs and Methods for Producing and Using Thereof
Cultured tissue constructs comprising cultured cells and endogenously produced extracellular matrix components without the requirement of exogenous matrix components or network support or scaffold...
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US20080097607 |
Pigmentable epidermis equivalent prepared from matrix cells and methods for the production thereof
Epidermis equivalents capable of pigmentation include cells derived from the differentiation of matrix cells; reconstructed skins comprised thereof, optionally containing hair follicles, are useful...
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US20080095751 |
Atherosclerosis
The present invention relates, in general, to atherosclerosis and, in particular, to a method of treating atherosclerosis and to cells suitable for use in such a method.
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US20080089870 |
Cultured Melanocytes on Bioploymer Membranes for Treatment of Hyper and Hypopigmentation Disorders
The present invention relates to a graft wherein cultured autologous melanocytes are delivered using a biopolymer. The present invention describes the composition, method of preparation and its...
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US20080089868 |
Retinal stem cell compositions and methods for preparing and using same
Provided are cell compositions including non-retinal cell types that have been reprogrammed to form retinal stem cells, and methods for producing and using same. Such reprogrammed cells can be used...
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US20080058278 |
ATTENUATION OF HYPEROXIA-INDUCED CELL DEATH WITH MITOCHONDRIAL ALDEHYDE DEHYDROGENASE
Oxygen toxicity is one of the major risk factors in the development of the chronic lung disease or bronchopulmonary dysplasia in premature infants. Using proteomic analysis, we discovered...
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US20080044899 |
Differentiated Cells Originating in Precursor Fat Cells and Method of Acquiring the Same
A method wherein differentiation of precursor fat cell lines originating in swine and mouse matured fat cells is induced so as to give cells having other functions; and cells having other functions...
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US20080031858 |
CELL-MATRIX MICROSPHERES, METHODS FOR PREPARATION AND APPLICATIONS
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