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US20090291459 |
HYBRIDOMA CAPABLE OF PRODUCING ANTI-DECTIN-1 MONOCLONAL ANTIBODY
A hybridoma capable of producing a monoclonal antibody against dectin-1, and a monoclonal antibody which specifically reacts with dectin-1.
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US20090291090 |
ANTI-CD33 ANTIBODIES AND METHOD FOR TREATMENT OF ACUTE MYELOID LEUKEMIA USING THE SAME
The present invention relates to antibodies that bind CD33. More particularly, the invention relates to anti-CD33 antibodies, fragments and homologues of these antibodies, humanized and resurfaced...
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US20090232734 |
ANTI-TISSUE FACTOR ANTIBODIES AND COMPOSITIONS
Isolated anti-tissue factor antibodies, immunoglobulins, cleavage products and other specified portions and variants thereof having enhanced ADCC activity, as well as anti-tissue factor antibody...
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US20090214560 |
BINDING MOLECULES TO THE HUMAN OX40 RECEPTOR
The present disclosure provides isolated binding molecules that bind to the human OX40R, nucleic acid molecules encoding an amino acid sequence of the binding molecules vectors comprising the...
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US20090175880 |
ANTIBODIES THAT BIND HUMAN DENDRITIC AND EPITHELIAL CELL 205 (DEC-205)
Isolated monoclonal antibodies which bind to human DEC-205 and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the...
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US20090137002 |
ANTI EPHB4 ANTIBODIES AND ANTIBODY FRAGMENTS
The invention concerns antibodies and antibody fragments, specifically recognising the EphB4 receptor comprising heavy chains and light chain, comprising light and heavy CDR's, and their use as...
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US20090124005 |
Enhanced Expression and Stability Regions
Expression-enhancing nucleotide sequences for expression in eukaryotic systems are provided that allow for enhanced and stable expression of recombinant proteins in eukaryotic cells. Enhanced...
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US20090117118 |
ANTIBODIES SPECIFIC FOR SCLEROSTIN AND METHODS FOR INCREASING BONE MINERALIZATION
Compositions and methods relating to antibodies that specifically bind to TGF-beta binding proteins are provided. These methods and compositions relate to altering bone mineral density by...
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US20090110686 |
Antibodies against CCR5 and uses thereof
An antibody binding to CCR5 characterized in that the heavy chain variable domain comprises an amino acid sequence of SEQ ID NO: 1, and has advantageous properties for the treatment of...
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US20090104662 |
Use of interleukin-4 antagonists and compositions thereof
Methods for treating medical conditions induced by interleukin-4 involve administering an IL-4 antagonist to a patient afflicted with such a condition. Suitable IL-4 antagonists include, but are...
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US20090047735 |
Antibodies Against Human G-Protein Chemokine Receptor (CCR5) HDGNR10
The present invention relates to a novel human protein called Human G-protein Chemokine Receptor (CCR5) HDGNR10, and isolated polynucleotides encoding this protein. The invention is also directed...
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US20080280322 |
Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
The present invention relates to the field of glycosylation engineering of proteins. More particularly, the present invention relates to glycosylation engineering to generate proteins with improved...
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US20080279859 |
NEUTRALIZING MONOCLONAL ANTIBODIES AGAINST THE NOGO-66 RECEPTOR (NgR) AND USES THEREOF
The subject invention relates to isolated proteins, particularly monoclonal antibodies, which bind to the Nogo-66 receptor. Specifically, these antibodies have the ability to inhibit the binding of...
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US20080187540 |
Antibodies to OCIF-binding molecules
A novel protein which binds to Osteoclastogenesis Inhibitory Factor (OCIF-binding molecule; OBM), a process for preparing the same, DNA encoding said protein, a protein having an amino acid...
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US20080152653 |
Anti-Alpha9 Integrin Antibody And The Use Thereof
The present invention provides an anti-mouse α9 integrin antibody, an anti-human α9 integrin antibody, a hybridoma producing any of the antibodies, a method of producing any of the antibodies and...
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US20080131445 |
CD127 EXPRESSION INVERSELY CORRELATES WITH FOXP3 AND SUPPRESSIVE FUNCTION OF CD4+ TREGS
The invention provides methods of isolating CD127 lo/− immunosuppressive regulatory T cells which can be greatly enriched for FoxP3, methods of expanding the isolated cells, pharmaceutical...
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US20080102072 |
MONOCLONAL ANTIBODIES TO TYPE I INTERFERON RECEPTOR
Anti-IFNAR1 monoclonal antibodies with neutralizing activities against the anti-viral cytopathic effects of various type I interferons are provided.
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