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US20120114700 LAT ADAPTER MOLECULE FOR ENHANCED T-CELL SIGNALING AND METHOD OF USE  
LAT (Linker for Activation of T-cells) is a protein involved in signaling through the T-cell receptor (TCR). The invention provides a LAT protein including mutations at ubiquitylation sites that...
US20110269175 METHODS FOR SORTING PARTICLES  
A method of sorting stained particles in a flow cytometer by generating a mathematical model based upon extracted features of waveform pulses produced in response to the stained particles....
US20110112196 NRF2 SCREENING ASSAYS AND RELATED METHODS AND COMPOSITIONS  
Provided are certain methods of screening, identifying, and evaluating neuroprotective compounds useful for treatment of neurological diseases, such as, e.g., multiple sclerosis (MS). The...
US20130336933 3-DIMENSIONAL SCAFFOLDS FOR IMPROVED DIFFERENTIATION OF PLURIPOTENT STEM CELLS TO HEPATOCYTES  
The present invention relates to the use of 3-dimensional (3D) synthetic or animal-derived bioscaffolds as substrates for the improved growth and differentiation of hPS (Human pluripotent stem...
US20130164266 3-DIMENSIONAL SCAFFOLDS FOR IMPROVED DIFFERENTIATION OF PLURIPOTENT STEM CELLS TO HEPATOCYTES  
The present invention relates to the use of 3-dimensional (3D) synthetic or animal-derived bioscaffolds as substrates for the improved growth and differentiation of hPS (Human pluripotent stem...
US20120039889 METHODS OF DIAGNOSING AND TREATING PROSTATE CANCER CHARACTERIZED BY NDRG1-ERG FUSION  
An in depth analysis of prostate cancer prostatectomy samples which over-express the ERG oncogene led to the discovery of a novel gene translocation in prostate cancer, between the NDRG1 gene...
US20150260977 COVER-SLIPS FOR AN OPTICAL MICROSCOPE AND RELATED METHODS  
A cover-slip suitable for use in examination by an optical microscope. The cover-slip comprises a planar portion of substantially rigid and transparent material and further comprises a tab...
US20140065655 SCREENING METHOD FOR SUBSTANCE ACTING ON MAINTENANCE OF EPITHELIAL PROPERTIES OF CELL  
A screening method for a substance acting on a maintenance of the epithelial properties of cells which enables obtainment of highly-reliable data quickly at low costs is provided. The screening...
US20120021450 METHODS FOR MAGNETIC RESONANCE IMAGING  
In certain aspects the present invention provides methods and compositions related to contrast agents for magnetic resonance imaging. In certain variations, contrast agents provided herein are...
US20110112040 SUPERCHARGED PROTEINS FOR CELL PENETRATION  
Compositions, systems and related methods for delivering a supercharged protein or a complex of a supercharged protein and therapeutic agent (e g, nucleic acid, peptide, small molecule) to cells...
US20120028263 METHOD FOR SCREENING A SALTY TASTE MODULATING SUBSTANCE  
By contacting a test substance with a cell that expresses a Kv3.2 protein, and comparing observed cation influx into the cell with cation influx into the cell observed when the test substance is...
US20110166066 CATESTATIN (CST) AND ITS VARIANTS FOR TREATMENT OF CARDIOVASCULAR AND METABOLIC DISORDERS  
Circulating levels of catestatin (Cts: human chromogranin A352-372) decrease in the plasma of patients with essential hypertension. Genetic ablation of the chromogranin A (Chga) gene in mice...
US20110053859 METHODS TO REDUCE THE EFFECTS OF SLEEP DEPRIVATION  
The invention provides methods of treating symptoms of sleep deprivation using a hypocretin agonist. The invention also provides methods of treating Parkinson's disease using a hypocretin agonist.
US20110159040 NOVEL IMMUNOGENS AND METHODS FOR DISCOVERY AND SCREENING THEREOF  
An aspect of the present invention provides for methods for identifying novel immunogens that when administered as vaccines elicit a cellular or humoral immunogenic response. In a particular...
US20120156711 System and method that allows the joined performance of optoelectric and respirometric sensors for instant and accurate ascertainment of biochemical oxygen demand (BOD) in liquid industrial wastes  
The present invention provides a system and method that combines the rapidity of the optoelectric signal and the simplicity of the respirometric cartridge wherein the greater accuracy of the...
US20150247124 Generation of Airway and Lung Progenitors and Epithelial Cells and Three-Dimensional Anterior Foregut Spheres  
Embodiments of the present invention are directed to various methods for generating airway and lung progenitors and epithelial cells and three-dimensional anterior foregut spheres, and to...
US20110027235 Targeted integration into stem cells  
Disclosed herein are methods and compositions for targeted integration of sequences of interest such as lineage-specific or cell fate reporter constructs or protein encoding sequences into stem cells.
US20110269167 MEDICAL APPARATUS FOR EXTRACORPOREAL BLOOD TREATMENT AND METHOD FOR DETERMINING A BLOOD PARAMETER VALUE IN A MEDICAL APPARATUS THEREOF  
A medical apparatus for extracorporeal blood treatment and a method for determining blood parameter value have been provided. The medical apparatus has a control unit (9) configured for taking...
US20150119327 DRUG SCREENING PLATFORM FOR RETT SYNDROME  
The invention provides a method for restoring a neural cell having a deficiency or alteration in glutamatergic pathway affecting neuron and/or glial function comprising contacting the cell with a...
US20140356893 COMPOSITIONS AND METHODS FOR USING PLATELET-RICH PLASMA FOR DRUG DISCOVERY, CELL NUCLEAR REPROGRAMMING, PROLIFERATION OR DIFFERENTIATION  
Methods are described for using compositions containing platelet-rich plasma for the treatment of a variety of tissue lesions, and the use of compositions containing platelet-rich plasma to...
US20100311666 COSMETIC USE OF A PROTEIN BELONGING TO THE RIBONUCLEASE FAMILY  
The present invention relates to the use, in cosmetics and in therapeutics, of at least one antimicrobial protein belonging to the ribonuclease family, ribonuclease 7, or of polypeptides derived...
US20140363838 MICROPERFUSION IMAGING PLATFORM  
This disclosure describes the design and function of a microfluidic device for performing time course assays on 2D or 3D-cell culture models designed to interface with existing robotic,...
US20150204848 FLUORESCENT CELL MARKERS  
The preparation and use of fluorescent cell markers of the structure F—S1-S2-L is described where F is a fluorophore, S1-S2 is a spacer linking F to L, and L is a diacyl lipid.
US20130344082 METHODS OF TREATING OR PREVENTING PERIODONTITIS AND DISEASES ASSOCIATED WITH PERIODONTITIS  
The present disclosure describes methods for preventing or treating periodontitis or diseases associated with periodontitis. The present disclosure also describes methods of screening for...
US20130034568 METHODS OF TREATING OR PREVENTING PERIODONTITIS AND DISEASES ASSOCIATED WITH PERIODONTITIS  
The present disclosure describes methods for preventing or treating periodontitis or diseases associated with periodontitis. The present disclosure also describes methods of screening for...
US20120015397 Periodontal Disease Marker (as amended herewith)  
A marker for determining the onset of periodontal disease and a marker for determining the progression stage of periodontal disease, each containing autoinducer-2.
US20140031245 ALZHEIMER'S DISEASE-SPECIFIC ALTERATIONS OF THE ERK1/ERK2 PHOSPHORYLATION RATIO-ALZHEIMER'S DISEASE-SPECIFIC MOLECULAR BIOMARKERS (ADSMB)  
The present invention relates to methods of diagnosing Alzheimer's Disease as well as to methods of confirming the presence or absence of Alzheimer's Disease in a subject. The present invention is...
US20140051063 HEMATOLOGY CONTROL COMPOSITIONS WITH EXTENDED STABILITY  
The present specification provides hematology control compositions having particular utility with a red blood cell component for devices using electronic and optical means for blood...
US20110136681 SELECTION OF STEM CELL CLONES WITH DEFINED DIFFERENTIATION CAPABILITIES  
Disclosed are methods for producing a clonal population of cells involving: a) obtaining a population of pluripotent or multipotent cells that have been expanded in vitro and maintained in an...
US20140086878 Muscodor albus Strain Producing Volatile Organic Compounds and Methods of Use  
Disclosed herein is an isolated Muscodor albus strain producing volatile organic compounds such as aristolene, 3-octanone and/or acetic acid ester, as well as cultures of said strain and...
US20120066780 HUMANIZED NSG MOUSE, METHOD OF PRODUCING THE SAME AND USE THEREOF  
A mouse model in which human fetal thymus and human fetal bone fragments are transplanted into NSG mice, a method of producing the same, and a use thereof.
US20120190055 MOLECULE BIOMARKERS OF AUTISM  
This invention provides methods and biomarkers for diagnosing autism by identifying cellular metabolites differentially produced in autistic patient samples versus non-autistic controls. Methods...
US20120238458 Novel tumor marker determination  
A method of determining gynaecologic tumor disease in a subject by providing a sample of peripheral blood of the subject, measuring the PPIC expression of cells in the sample, and comparing this...
US20080213214 Treating Cardiovascular Tissue  
This document provides methods and materials for treating cardiovascular tissue. For example, stem cells, compositions containing stem cells, methods for obtaining stem cells, compositions for...
US20130059783 COMPOSITIONS AND METHODS FOR EXPANDING BFU-E CELLS  
The invention provides methods of expanding BFU-E cells comprising contacting one or more BFU-E cells with a hypoxia inducible factor 1 activator and a glucocorticoid receptor (GR) activator,...
US20100310563 METHODS FOR TREATING INDUCED CELLULAR PROLIFERATIVE DISORDERS  
Methods are provided for treating a subject with a cellular proliferative disorder that include administering to the subject a therapeutically effective amount of a JAK2 inhibitor and a...
US20120100568 SERUM-FREE MEDIUM FOR INDUCING PLURIPOTENT STEM CELLS QUICKLY WITH HIGH EFFICIENCY AND METHOD USING THEREOF  
A serum-free medium for inducing and reprogramming somatic cells into induced pluripotent stem cells (iPS) quickly with high efficiency, and the method using thereof for inducing and reprogramming...
US20120237965 SYSTEMS AND METHODS FOR A CONTINUOUS CULTURE BIOSENSOR  
A continuous culture system of genetically modified yeast or another biological organism detects contaminants in water through production of a fluorescent chemical continuously produced by the...
US20110150758 TRACKING OF BONE MARROW CELLS FOR METASTASIS SCREENING  
At least one embodiment of the invention relates to bone marrow precursor cells or bone marrow cells of a patient, the cells labeled with at least one contrast agent suitable for an imaging...
US20110281295 METHOD AND DEVICE FOR CULTURING ALGAE  
According to one aspect, the invention relates to a device for culturing algae with natural light, including an enclosure with a culturing medium and the algae to be cultured, and a substrate...
US20110287470 CELL CULTURE METHOD TO FORM AGGREGATES  
The invention relates to the field of cell and tissue culture. In particular, the invention provides methods for culturing cells to form aggregates, including stem cells and primary cells. A...
US20120122073 CIS DI-AHL MODIFIED CONTROLS FOR GLYCATED HEMOGLOBIN S-A1C DERIVED FROM HEALTHY BLOOD CELLS  
The invention is composition comprising red blood cells in an aqueous suspension medium and one or more cis di-ahls; wherein more than 6 percent by weight of the hemoglobin in the red blood cells...
US20140178366 PRESELECTION OF SUBJECTS FOR THERAPEUTIC TREATMENT BASED ON HYPOXIC STATUS  
The present invention provides methods for the preselection of a subject for therapeutic treatment with an agent based on modulated levels of hypoxia in cancerous cells in the subject. In one...
US20120128665 PRESELECTION OF SUBJECTS FOR THERAPEUTIC TREATMENT BASED ON HYPOXIC STATUS  
The present invention provides methods for the preselection of a subject for therapeutic treatment with an agent based on modulated levels of hypoxia in cancerous cells in the subject. In one...
US20120122145 INSECT-BASED EX VIVO MODEL FOR TESTING BLOOD-BRAIN BARRIER PENETRATION AND METHOD FOR EXPOSING INSECT BRAIN TO CHEMICAL COMPOUNDS  
There is provided an ex-vivo insect screening model to accurately determine blood-brain barrier penetration of different chemical compounds in order to improve the compound screening...
US20120149025 Screening Methods for Human Embryonic Stem Cells  
This disclosure provides an improved system for culturing human pluripotent stem cells. Traditionally, pluripotent stem cells are cultured on a layer of feeder cells (such as mouse embryonic...
US20140072993 SENSOR PROBE FOR BIO-SENSING AND CHEMICAL-SENSING APPLICATIONS  
The basic structure and functionality of a probe as disclosed herein allows for flexibly incorporating into the probe, various sensing elements for various sensing applications. Two example...
US20130129627 Delivery of Nanoparticles to Neurons  
A peptide attached to a nanoparticles (such as quantum dots) selectively directs the nanoparticles to neurons in a tissue or organism.
US20110206612 NOVEL SCREENS TO IDENTIFY AGENTS THAT MODULATE RETINAL BLOOD VESSEL FUNCTION AND PERICYTE FUNCTION AND DIAGNOSTIC AND THERAPEUTIC APPLICATION THEREFOR  
The present invention provides methods for determining or identifying compounds that modulate the function of an isolated retinal pericyte or blood vessel, wherein a change in the contractile...
US20090263377 IL-32B-TARGETED DIAGNOSIS AND THERAPY  
Methods for the diagnosis and treatment of IL-32β over-expressing cancers are provided. Also provided are methods for the treatment of wounds, hair loss and the promoting and/or restoration of...