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US20110294144 SCREENING METHOD  
The present invention provides a cell model system capable of sufficiently reproducing a series of tau lesions, and provides a screening method for a prophylactic or therapeutic drug for a...
US20120178119 METHOD FOR MEASURING AUTOPHAGY  
This invention relates to a method for measuring autophagy in cells, comprising using, as a probe reagent, a single fluorescent protein, to measure a change in fluorescence properties of the...
US20150056252 Composition and Method for Diagnosis and Immunotherapy of Lung Cancer  
The present invention includes compositions and methods for the diagnosis and treatment of lung cancer with a recombinant tumor-associated antigen loaded antigen presenting cell that generates a...
US20130198876 INDUCED MALIGNANT STEM CELLS OR PRE-INDUCTION CANCER STEM CELLS CAPABLE OF SELFREPLICATION OUTSIDE OF AN ORGANISM, PRODUCTION METHOD FOR SAME, AND PRACTICAL APPLICATION FOR SAME  
The present invention provides an induced cancer cell capable of self-replication in vitro which is useful in cancer therapy research and the research for cancer-related drug discovery, processes...
US20120070849 METHODS AND COMPOSITIONS FOR RISK STRATIFICATION  
The present invention provides an approach for the simultaneous determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of...
US20110207149 METHODS AND COMPOSITIONS FOR RISK STRATIFICATION  
The present invention provides an approach for the simultaneous determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of...
US20110201018 METHODS AND COMPOSITIONS FOR RISK STRATIFICATION  
The present invention provides an approach for the simultaneous determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of...
US20140273061 Reagents, Systems and Methods for Analyzing Erythrocytes and Platelets  
Aspects of the invention include hematology analysis reagents, systems and methods that can be used to preserve blood cell morphology and integrity as well as provide sample integrity and optical...
US20110311495 ISOLATED POPULATIONS OF RENAL STEM CELLS AND METHODS OF ISOLATING AND USING SAME  
Isolated populations of fetal renal stem cells and progenitor cells are provided. Also provided are methods of generating and using these isolated populations of cells.
US20140349330 METHODS FOR AGGREGATION AND DIFFERENTIATION OF MAGNETIZED STEM CELLS  
The invention relates to a process which enables optimal aggregation of cells, typically of stem cells, promoting the organisation thereof and advantageously the differentiation thereof, in...
US20110027821 METHOD OF BIOASSAYING YOKUKANSAN  
The invention intends to find out a bioassay system with an in-vitro test capable of ensuring the higher quality of yokukansan, and provides a bioassay method for yokukansan, comprising adding...
US20110280914 HYDROGELS CROSSLINKED WITH GOLD NANOPARTICLES AND METHODS OF MAKING AND USING THEREOF  
Described herein are composites useful in tissue and organ engineering. In one aspect, the composite comprises the reaction product between a macromolecule comprising at least one thiol group and...
US20150010513 Human Brown Adipose Derived Stem Cells and Uses  
An isolated human brown adipose tissue stem cell line. In one embodiment, the isolated human brown adipose tissue stem cell line expresses the markers CD9, SSEA4, CD44, CD90, CD166, CD73, but not...
US20100313291 Methods for Improving the Yield of Cucumber Plants  
The present invention relates to a plant of a cucumber breeding line having an introgression from cucumber accession PI 169383, a representative sample of seed of which has been deposited with the...
US20140127679 Chemical probe compounds that become fluorescent upon reduction, and methods for their use  
Chemical stain compounds containing a fluorophore and a reducible quenching unit are disclosed. The reducible quenching unit quenches the fluorophore while in its oxidized state. Upon reduction,...
US20110117591 CHEMICAL PROBE COMPOUNDS THAT BECOME FLUORESCENT UPON REDUCTION, AND METHODS FOR THEIR USE  
Chemical stain compounds containing a fluorophore and a reducible quenching unit are disclosed. The reducible quenching unit quenches the fluorophore while in its oxidized state. Upon reduction,...
US20150051102 MULTIFUNCTIONAL NANOPARTICLES FOR MOLECULAR AND CELLULAR SEPARATION, DETECTION AND QUANTIFICATION  
The present disclosure provides compositions and methods useful for molecular and cellular separation, detection and quantification. The compositions provided herein comprise a nanostructure...
US20110224243 FZD2 Molulators in the Treatment of Alopecia  
An in vitro method for screening candidate compounds for the preventive or curative treatment of alopecia is described. The method can include determining the capacity of a compound to modulate...
US20130184178 Methods of Detecting Autoimmune or Immune-Related Diseases or Conditions  
The disclosure provides methods of using phagocytic cells alone or in combination with non-phagocytic cells in the diagnosis, prognosis, or monitoring of autoimmune or immune-related diseases or...
US20110262465 PROSTATE STEM CELLS AND USES THEREOF  
Prostate stem cells and prostate cancer stem cells and their use in treating prostate cancer and regenerating prostate tissue are disclosed.
US20150198584 IDENTIFICATION OF FUNCTIONAL CELL STATES  
Embodiments herein described provide methods for determining phenotypic parameters of cell populations and expressing them in terms of tensors that can be compared with one another. Embodiments...
US20100330602 Use of Soluble Galectin-3 (Gal-3) for Cancer Treatment  
The present invention provides a method for preventing or treating cancer or tumorgenesis disorder comprising administering a prevention or treatment effective amount of a p53 mediated secretome...
US20140072994 METHODS OF ANAEROBIC DIGESTION OF BIOMASS TO PRODUCE BIOGAS  
Improved methods for anaerobic digestion of organic matter to produce biogas. Among the improvements given are including ferric iron in a hydrolysis reactor to increase the rate and efficiency of...
US20100319078 Stem Cells Modified to Facilitate Threonine Catabolism  
A mammalian cell comprising a recombinant, functional L-threonine 3-dehydrogenase (EC 1.1.1.103; TDH) gene, methods of making, and methods of use.
US20140127737 VARIABLE COLOR TWO-PHOTON FLUORESCENT PROBE, METHOD FOR IMAGING THIOL ACTIVATION IN MITOCHONDRION USING SAME, AND METHOD FOR MANUFACTURING THE VARIABLE COLOR TWO-PHOTON FLUORESCENT PROBE  
The present invention relates to a two-photon fluorescent probe, more particularly a two-photon fluorescent probe represented by Formula 1, a method for preparing same and a method for imaging...
US20120129207 COMPOSITIONS AND METHODS OF FUNCTIONALLY ENHANCED IN VITRO CELL CULTURE SYSTEM  
Compositions and methods described herein provide a cell culture system in which cells are in high metabolic states from the onset of the culture. Combinations of various cell culture components...
US20110015090 Markers of Acute Myeloid Leukemia Stem Cells  
Markers of acute myeloid leukemia stem cells (AMLSC) are identified. The markers are differentially expressed in comparison with normal counterpart cells, and are useful as diagnostic and...
US20110318773 METHOD TO USE EKTACYTOMETRY TO IMPROVE STORED RED BLOOD CELL OR WHOLE BLOOD PRODUCT UTILIZATION  
A method for assessing the quality degradation of an RBC or whole blood unit, the method comprising: 1) using an ektacytometer to generate erythrocyte deformability data for the RBC or whole blood...
US20110269171 METHODS AND MATERIALS FOR USING NKAP POLYPEPTIDE EXPRESSION LEVELS OR PATTERNS TO DETECT OR ASSESS CANCER  
This document relates to methods and materials involved in detecting or assessing cancer (e.g., ovarian cancer). For example, methods and materials involved in using NKAP polypeptide expression...
US20110318749 METHOD FOR IDENTIFYING REGULATORY T CELLS  
The present invention relates to methods and kits for identifying, quantifying and isolating regulatory T cells, to methods and kits for diagnosing or monitoring autoimmune diseases,...
US20110039291 Bioremediation of Nanomaterials  
The present invention provides a method comprising the use of microorganisms for nanotoxicity study and bioremediation. In some embodiment, the microorganisms are bacterial organisms such as Gram...
US20120295296 Chlorite in the Treatment of Neurodegenerative Disease  
The invention features methods of treating a macrophage-associated neurodegenerative disease such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), or multiple sclerosis (MS) in a...
US20150045248 METHOD FOR IDENTIFYING DISEASE ASSOCIATED WITH ABUNDANCE OF TDP-43 IN CELL  
The present invention aims to develop and provide a method for identifying a disease associated with the abundance of TDP-43 in cells and a method for producing a TDP-43 binding inhibitor. By...
US20110076683 Identification, Isolation and Elimination of Cancer Stem Cells  
Isolated populations of leukemic stem cells are provided. The cells are useful for experimental evaluation, and as a source of lineage and cell specific products, and as targets for the discovery...
US20140024066 ANIMAL MODEL HAVING PHOTO-ACTIVATABLE MITOCHONDRIA  
An animal model includes a photo-activatable fluorescent protein that can conditionally label the mitochondria throughout the animal or in selective animal cells and tissues, allowing for...
US20130150430 Methods for Impairing the P53/HDM2 Auto-Regulatory Loop in Multiple Myeloma Development Using mIR-192, mIR-194 and mIR-215  
Methods and compositions for detecting, treating, characterizing, and diagnosing multiple myeloma are described.
US20110230811 PATTERNED GRADIENT WOUND DRESSING AND METHODS OF USING SAME TO PROMOTE WOUND HEALING  
The present invention provides a wound dressing that includes a patterned gradient of immobilized growth factor molecules that promote directed migration of cells during dermal wound healing....
US20110207163 METHOD FOR AND MATERIAL OF A SHAPE STANDARD  
A method is disclosed for the preparation of isomorphic and nonspherical shape standards as isometric as possible and their mixtures for validation of the measurement methods and analyzers for...
US20150079135 METHODS FOR TREATING AND MONITORING THE STATUS OF CANCER  
Provided herein are methods for treating cancer in a subject comprising administering to the subject a therapeutically effective amount of a peptide derived from the EphA2 protein and/or the...
US20120283193 MANIPULATION OF BRAIN IN A CIRCUIT-SPECIFIC MANNER  
The present invention relates generally to methods, devices and compositions for treating mental, neurological, and cognitive diseases related to deficiencies in the biosynthesis and/or metabolism...
US20130084275 Methods and Compositions for Reducing Interleukin-4 or Interleukin-13 Signaling  
The present invention relates generally to methods and compositions for reducing Interleukin-4 or Interleukin-13 signaling, in particular to treat asthma and atopic dermatitis. The inventors have...
US20150017663 IDENTIFICATION OF ANTITUMOR COMPOUNDS USING PLACENTA  
Provided herein are methods of evaluating potential antitumor compounds, and thereby identifying antitumor compounds, using placenta or a portion thereof and tumor cells, and compositions for...
US20110165570 METHOD OF EFFECTING DE-DIFFERENTIATION OF A CELL  
The invention provides a method of effecting de-differentiation of an at least partially differentiated cell or of maintaining pluripotency and/or self-renewing characteristics of an...
US20110086379 Method of Differentiating Stem Cells  
The present disclosure provides methods of generating germ layers from stem cells comprising culturing the stem cells in a culture medium having an osmolality less than 340 mOsm/kg. The present...
US20150105436 Methods and Assays for Detecting and Treating Hypoglycemia  
Methods for regulating glucagon release and of treating hypoglycemia, and for screening drug candidates for heating hypoglycemia. The methods are useful for treating diabetes melititus and...
US20120071341 NOVEL METHODS FOR PREDICITING AND TREATING TUMORS RESISTANT TO DRUG, IMMUNOTHERAPY AND RADIATION  
The present invention relates to methods for prognosis, diagnosis, and treatment of malignant tumors that were treatment resistant. The present invention provides methods of prognosis and...
US20120010092 Methods for Identifying Fragile Histidine Triad (FHIT) Interaction and Uses Thereof  
Provided herein are methods and compositions for the diagnosis, prognosis and treatment of a cancer associated disorder using the Fhit gene.
US20150132788 ESTABLISHING THE VIABILITY OF BIOLOGICAL SAMPLES  
The invention relates to a method, a use and a kit for establishing the viability (ability to live) of biological samples using ageladine A. The invention is advantageously suitable for...
US20150111225 METHOD FOR IN VITRO DIFFERENTIATION OF BLOOD CIRCULATING CELLS INTO NEURONAL-LIKE CELLS AND APPLICATIONS THEREOF  
The present invention relates to a method for in vitro differentiation of a population of blood circulating cells, such as monocytes and preferably pluripotent macrophages derived therefrom, into...
US20110224149 POLYNUCLEOTIDES FOR USE IN TREATING AND DIAGNOSING CANCERS  
The present invention provides methods for increasing sensitivity of cancer cells to an antiestrogen agent, such as a selective estrogen receptor modulator (SERM). The methods include...