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US20110091429 Methods for Enhancing Stem Cell Engraftment During Transplantation  
The present invention relates to the fields of hematopoietic stem cell transplantation and molecular biology. More specifically, methods for improving engraftment efficiency in stem cell...
US20100305000 METHOD AND USE OF MICROARRAY TECHNOLOGY AND PROTEOGENOMIC ANALYSIS TO PREDICT EFFICACY OF HUMAN AND XENOGRAPHIC CELL, TISSUE AND ORGAN TRANSPLANT  
The present invention is directed to systems and proteogenomic methods for predicting the success of the transplant of a cell, tissue, or organ by providing a means to determine the quality of the...
US20110280844 HEPATOCYTE PRODUCTION BY FORWARD PROGRAMMING  
The invention generally features methods for providing hepatocytes from a variety of cell sources, particularly pluripotent stem cells, therapeutic compositions featuring such cells, and methods...
US20110236882 QUANTITATIVE MEASUREMENT OF NANO/MICRO PARTICLE ENDOCYTOSIS WITH CELL MASS SPECTROMETRY  
Methods for detecting the presence of nanoparticles or microparticles by cell mass spectrometry (CMS) are provided. CMS methods are provided for determining the number of nanoparticles or...
US20110305677 HUMAN EMBRYONIC STEM CELL CULTURES, AND COMPOSITIONS AND METHODS FOR GROWING SAME  
Human pluripotential embryonic stem cell cultures are provided, as are human feeder cells useful for growing the human embryonic stem cells, conditioned medium obtained from cultures of the human...
US20110014602 Diagnostic composition for hepatocellular carcinoma, a diagnostic kit comprising it and diagnostic methods of hepatocellular carcinoma  
In the present invention, it is confirmed that cystatin B (cystatin B, CSTB) can be used as a diagnostic marker for hepatocellular carcinoma. Accordingly, the invention relates to a method for...
US20120088248 IN VITRO METHODS FOR DETERMINING AN INTRACELLULAR FREE MAGNESIUM DEFICIENCY OF INDIVIDUALS BY DETERMINING THE EXPRESSION RATE OF A CELLULAR MG2+ TRANSPORTER GENE  
An in vitro method is disclosed for determining the presence or absence of an intracellular free magnesium deficiency in a human individual by determining the expression rate of at least one...
US20150017677 CANCER STEM CELLS  
Cancer stem cell populations characterized by expression of CD44hi, ABCG2, β-catenin, CD117, CD133, ALDH, VLA-2, CD166, CD201, IGFR, and/or EGF1R, and methods of isolating and using the same.
US20130244268 CANCER STEM CELLS EXPRESSING ABCG2  
Cancer Stem Cell populations characterized by expression of ABCG2 and methods of isolating and using the same are disclosed.
US20110244501 CANCER STEM CELLS  
Cancer stem cell populations characterized by expression of CD44hi, ABCG2, β-catenin, CD117, CD133, ALDH, VLA-2, CD166, CD201, IGFR, and/or EGF1R, and methods of isolating and using the same.
US20110076694 METHOD OF ASSESSING MAMMALIAN EMBRYO QUALITY  
A method of assessing the health of each oocyte or embryo of a mammal from a plurality of oocytes/embryos of the mammal is provided. The method comprises the steps of: measuring gap junctional...
US20140243227 CULTURE MEDIA FOR STEM CELLS  
Culture media and methods for expanding and differentiating populations of stem cells and for obtaining organoids. Expanded cell populations and organoids obtainable by methods of the invention...
US20150174059 ORAL CARE  
Various disclosed embodiments relate to oral care are presented. In particular, one embodiments includes to an oral care composition for inhibiting the growth of potentially pathogenic oral...
US20130157302 METHOD FOR DETERMINING CAPABILITY OF A COMPOUND FOR INHIBITING A RECEPTOR USING CODON-OPTIMIZED NUCLEIC ACID  
A method for determining a capability of a compound for inhibiting a receptor through a change of intracellular calcium ion when the receptor is activated is provided. Contacting a host cell...
US20150047061 Humanized M-CSF Mice  
Genetically modified mice comprising a nucleic acid sequence encoding a human M-CSF protein are provided. Also provided are genetically modified mice comprising a nucleic acid sequence encoding a...
US20150072372 SYSTEM AND METHODS FOR CONDUCTING IN VITRO EXPERIMENTS  
The present invention is a system and methods by which in vitro experiments directed to a subject may be managed more efficiently. More particularly, the present invention is a system and methods...
US20130288285 METHODS FOR PREDICTING CARDIAC TOXICITY  
Methods are disclosed for determining whether organ toxicity, particularly cardiotoxicity, will occur in a patient selected for treatment with various kinase inhibitors, such as tyrosine kinase...
US20120020977 PANCREATIC CANCER GENES  
The present invention provides the art with the DNA coding sequences of polynucleotides that are up-or-down-regulated in cancer and dysplasia. These polynucleotides and encoded proteins or...
US20100304996 B CELL SIGNATURE ASSOCIATED WITH TOLERANCE IN TRANSPLANT RECIPIENTS  
The present invention provides methods for predicting the development of tolerance to a transplant, such as a kidney, using molecular markers that have different expression patterns in tolerant...
US20120322088 METHODS FOR THE DIAGNOSIS, RISK ASSESSMENT, AND MONITORING OF AUTISM SPECTRUM DISORDERS  
Methods for the diagnosis, risk assessment, and monitoring of Autism Spectrum Disorder (ASD) are disclosed. More specifically the present invention relates to the measurement of small molecules...
US20080138850 Skin Model  
The present invention relates to the use of a pig skin sample as a skin model, particularly for the assessment of pharmacological and cosmetic effects.
US20100317042 PROTEINS ACTIVATING PRO-PHENOLOXIDASE SYSTEM AND GENES ENCODING THE SAME  
The present invention provides novel proteins activating pro-phenoloxidase (pro-PO) system of Tenebrio molitor, genes encoding the same, methods of detecting bacterial infection in a sample using...
US20130089869 Methods For and Uses of Mechanical Stiffness Profiling of Cancer Cells  
Methods of predicting the invasiveness or metastatic potential of cancer cells are provided herein. Methods of screening for cancer cells or diagnosing cancer in a subject are also provided....
US20110288020 Use of VEGF and homologues to treat neuron disorders  
The present invention relates to neurological and physiological dysfunction associated with neuron disorders. In particular, the invention relates to the involvement of vascular endothelial growth...
US20110159478 METHOD FOR SCREENING DRUG CANDIDATES BY USING DOMAIN PROTEIN  
The present invention relates to a method for screening and discovering bioactive materials using specifically selected protein domains interacting with specific intracellular proteins, and more...
US20110300574 CELL-COUNTING METHOD FOR BLOOD HEMOLYSIS ANALYSIS IN FRAGILITY MEASUREMENT  
A method of using cell counting to determine how much hemolysis occurs when a sample of red blood cells is subjected to stress, for purposes of either assessing stored blood quality and/or...
US20100203572 METHOD FOR CARRYING OUT AND EVALUATING MIX & MEASURE ASSAYS FOR THE MEASUREMENT OF REACTION KINETICS, CONCENTRATIONS AND AFFINITIES OF ANALYTES IN MULTIPLEX FORMAT  
The invention relates to a method comprising the following steps: a) use of a support which has at least two different microparticle populations immobilized thereon; b) measuring the fluorescence...
US20110275104 Device and Method for Detection of Humidity-Compromised Urine Test Strips  
The timing of the reaction of moisture-sensitive reagents for detecting the presence of analytes, e.g. leukocytes in urine samples, is used to detect when the reagents have been compromised by...
US20110262480 Method for producing multiple modifications in the chromosome of gram-negative bacteria and salmonella strains which are deficient in c-di-GMP synthesis obtained by said method  
Method for producing multiple modifications in the chromosome of Gram-negative bacteria and Salmonella strains which are deficient in c-di-GMP synthesis obtained by said method. The method can be...
US20130196314 Genes Differentially Expressed in Breast Cancer  
A polynucleotide sequence as shown in SEQ ID NO:1 is associated with metastatic potential of cancer cells, especially breast cancer cells. Methods are provided for determining the risk of...
US20130344501 METHODS FOR PRODUCING THREE-DIMENSIONAL PHYSIOLOGICALLY RELEVANT IMMUNE TISSUE SYSTEMS UNDER LOW FLUID SHEAR CONDITIONS  
Methods of producing a three-dimensional, physiologically relevant immune tissue system, including culturing an immune cell and at least one other cell type separately; placing immune cell and the...
US20110275105 Methods of inducing pluripotency  
Methods are provided for inducing non-pluripotent cells to become pluripotent. Methods also include identifying and isolating induced pluripotent (iPS) cells and uses thereof. Compositions and...
US20120272342 MOUSE ARTIFICIAL CHROMOSOME VECTOR  
Disclosed is a mouse artificial chromosome vector, comprising: a natural centromere derived from a mouse chromosome; a mouse-chromosome-derived long-arm fragment formed by deleting a long-arm...
US20150056625 REAGENT FOR CLARIFYING EMULSIONS AND METHOD OF CLARIFICATION  
A novel reagent for clarification of an emulsion containing a salt and first and second surfactants is used in a method of clarifying emulsions which may contain inorganic, organic or biological...
US20130195755 MICELLULAR COMBINATION COMPRISING A NANOPARTICLE AND A PLURALITY OF SURFMER LIGANDS  
The field of the present invention relates to the stabilisation of nanoparticles in aqueous dispersion and, in particular, the stabilisation of nanoparticles by encapsulating the nanoparticles in...
US20140243289 PRODRUGS OF MODULATORS OF ABC TRANSPORTERS  
The present invention relates to prodrugs of modulators of ABC transporters, particularly, CFTR modulators, compositions thereof, and methods therewith. The present invention also relates to...
US20120171695 SPONTANEOUSLY CONTRACTING FISH CELL AGGREGATES, USE THEREOF AND METHOD FOR THE PRODUCTION THEREOF  
The invention relates to an in vitro method for producing spontaneously contracting fish cell aggregates, to the fish cell aggregates obtained thereby, and to the use thereof, in particular for...
US20120190573 BIOMARKER OF LUNG CANCER  
The present invention provides methods of providing a prognosis for a lung cancer in a subject and methods of predicting the risk of metastasis of a lung cancer in a subject. The present invention...
US20090186370 DIAGNOSTIC BIOMARKERS FOR VASCULAR ANEURYSM  
Biomarkers for diagnosis and monitoring of vascular aneurysms are described in the context of the use of assays to measure a plurality of these biomarkers. Tissue degeneration, particularly...
US20140370539 HEMOLYSIS REAGENT COMPOSITION FOR HEMOGLOBIN A1C QUANTITATIVE ANALYSIS USING ENZYMATIC METHOD  
Disclosed is a hemolysis reagent composition for the quantitative analysis of glycated hemoglobin (HbAlc) via an enzymatic method. The hemolysis reagent compositions of the present invention...
US20130036518 ORGANISM WITH ALTERED CAROTENOID CONTENT AND METHOD OF PRODUCING SAME  
The present invention relates to means and methods for modifying the expression of a component in the carotenoid biosynthetic pathway to modify the production of carotenoid towards accumulation of...
US20150232810 METHODS OF PREPARING PLURIPOTENT STEM CELLS  
The invention relates to pluripotent stems cells and their methods of use. The invention also relates to methods of producing pluripotent stem cells.
US20110270060 DEVICE AND METHODS FOR MONITORING THE ADMINISTRATION OF A STEM CELL TRANSPLANT  
A device and methods for the real-time monitoring of stem cells in a stem cell transplant. The device comprises a linear member and particle detection device configured to occupy the lumen of a...
US20110223599 PARASITE DETECTION VIA ENDOSYMBIONT DETECTION  
The present invention provides systems, methods, and compositions for identifying a subject as infected with a parasite by detecting nucleic acid from an endosymbiont of the parasite in a sample...
US20120045476 LIVE ATTENUATED MYCOPLASMA STRAINS  
The present invention provides live, attenuated Mycoplasma bacteria that exhibit reduced expression of one or more proteins selected from the group consisting of pyruvate dehydrogenase,...
US20120282597 BIOMARKER AND METHOD FOR EVALUATING RISK OF PROLIFERATION, INVASION, OR METASTASIS OF CANCER  
The present invention relates to a biomarker associated with a cancer and a method using the biomarker to evaluate a risk of proliferation, invasion, or metastasis of a cancer. The method of the...
US20130288260 Compositions and Methods For Enhancing the Biological Response to Chemical Agents and Physical Stimuli  
The present invention relates to compositions and methods configured to deliver a stimulus (e.g., a therapeutic agent or a therapeutically beneficial signal) to a cell, tissue, organ, or organism....
US20140106391 METHOD FOR DETECTING AND QUANTIFYING A TARGET MOLECULE IN A TISSUE  
The invention relates to a method for preparing a dilution range of at least one standard molecule for a tissue, whereby a tissue homogenate is used, to which the standard molecule is added, the...
US20140336109 MODULATION OF GHRELIN LEVELS AND GHRELIN/UNACYLATED GHRELIN RATIO USING UNACYLATED GHRELIN  
A method and a composition for decreasing ghrelin levels and/or decreasing ghrelin/unacylated ghrelin ratio in a subject, the method comprising administering an effective amount of unacylated...
US20130143247 VOLATILE ORGANIC COMPOUNDS FOR DETECTING CELL DYSPLASIA AND GENETIC ALTERATIONS ASSOCIATED WITH LUNG CANCER  
The present invention provides methods of identifying a genetic abnormality such as mutation in EGFR or KRAS or ALK which is associated with the management of lung cancer or diagnosing, prognosing...