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US20120164074 METHODS OF DIAGNOSING, PREVENTING AND TREATING CANCER METASTASIS  
The invention relates to methods and compositions for inhibiting metastasis, such as by inhibiting FOXC2 expression or activity. The invention further relates to methods of prognosticating,...
US20120021401 DISPOSABLE CARTRIDGE FOR AUTOMATIC AND CONTINUOUS WATER QUALITY MONITORING  
A disposable cartridge for use in assaying an analyte in an automated water quality monitoring analyzer comprising: (a) a platform; (b) array of containers for separately containing at least one...
US20120021448 METHOD FOR EVALUATING STATE OF CELLS  
Provided are a novel marker of the state of cells and the differentiation level of the same which is usable as a substitute for a gene or a protein; a means for quantitatively understanding this...
US20120128586 METHOD FOR TREATING CHRONIC LYMPHOCYTIC LEUKEMIA  
The present invention provides a method for treating a subject having chronic lymphocytic leukemia (CLL) comprising administering to the subject one or more agents that target cell surface...
US20130071330 METHODS OF IDENTIFYING AGENTS EFFECTIVE TO TREAT COGNITIVE DECLINE AND DISEASES ASSOCIATED THEREWITH  
Embodiments described herein are directed to methods of identifying agents effective to treat cognitive decline and diseases associated therewith. Embodiments described herein are also directed to...
US20100303797 Use of p97 As An Enzyme Delivery System For The Delivery of Therapeutic Lysosomal Enzymes  
The present invention provides for compositions and methods for treating, ameliorating or preventing a lysosomal storage disease by administering to a patient suffering from a lysosomal storage...
US20150212072 FUNCTIONAL ASSAY FOR CANCER RECURRENCE AND MALIGNANT POTENTIAL  
Embodiments herein provides an in vitro co-culture system comprising a population of cancer responder cells and a population of non-tumor cells wherein the cancer responder cells can convert to a...
US20120202197 EFFICIENT PROLIFERATION METHOD FOR A KUPFFER CELL AND USE THEREOF  
The present invention has successfully established a mixed culture system capable of actively proliferating a Kupffer cell in a primary culture of a cell population derived from a liver....
US20120135451 Method and Apparatus for Evaluation of Toxicity  
The present invention pertains to a method for evaluation of the toxicity of compounds comprising the use of spermatozoa. The inventions also relates to a high throughput system for the toxicity...
US20110318725 CELL CULTURE METHOD, CELL CULTURE DEVICE, METHOD FOR COUNTING SUBSJECT MATTERS TO BE COUNTED IN CONTAINER AND DEVICE FOR COUNTING  
Cell aggregate formation control and cell aggregate disintegration control are carried out with respect to cells in a culture container to increase cell proliferation efficiency. The number of the...
US20150160224 QUANTITATION OF BIOMARKERS FOR THE DETECTION OF PROSTATE CANCER  
The present invention provides biomarkers that are useful in determining whether a subject has cancer, specifically prostate cancer. Specifically, betaine, malate, proline, N-acetylaspartate,...
US20110159527 METHODS AND KITS FOR DIAGNOSING NEURODEGENERATIVE DISEASE  
Methods and diagnostic kits for determining whether a subject may develop a or for diagnosing a neurodegenerative disease. The method includes quantitating the amount of alpha-synuclein and total...
US20150212065 Methods using Axl as a biomarker of epithelial-to-mesenchymal transition  
The present invention relates to the use of AxI as a biomarker for detecting the occurrence of epithelial-to-mesenchymal transition (EMT) in a subject. More specifically, the invention relates to...
US20130309697 BIOMARKERS FOR PROSTATE CANCER AND METHODS USING THE SAME  
Methods for identifying and evaluating suites of biochemical and/or gene entities useful as biomarkers for early prediction of prostate cancer, disease grading, target identification/validation,...
US20120328630 METHODS FOR TREATING AND/OR LIMITING DEVELOPMENT OF DIABETES  
The present invention provides methods for identifying candidate compounds for limiting development of and/or treating diabetes, and methods for limiting development of and/or treating diabetes.
US20090203536 Assay supports comprising a peg support, said support attached from a peg solution in cloud point (theta solvent) conditions  
Assay supports, such as microarrays and similar devices, and methods of use and manufacture thereof, are described. The assay support is capable of assaying binding and/or activity of a bioactive...
US20120107244 MONOMERIC VARIANTS OF THE TETRAMERIC eqFP611  
Monomeric eqFP611 variants exhibit red fluorescent properties and DNA encoding monomeric eqFP611 variants.
US20120034643 FLUORESCENT PROTEIN  
An object of the present invention is to provide a red or orange fluorescent protein, which is characterized in that the difference (stokes shift) between an excitation peak value (wavelength of...
US20110124032 Methods and Compositions for Treating Carcinoma Stem Cells  
Cancer stem cells (CSCs) have been prospectively isolated or identified from primary tumor samples, and shown to possess the unique properties of self-renewal and differentiation, and can form...
US20140178305 IDENTIFICATION AND USE OF ANXIOLYTIC COMPOUNDS  
The present disclosure provides methods and compositions that can be used to identify anxiolytic compounds, and to treat anxiety in a subject. Methods and compositions for identifying activating...
US20130167257 METHODS OF SEED BREEDING USING HIGH THROUGHPUT NONDESTRUCTIVE SEED SAMPLING  
The present invention provides for novel methods to facilitate germplasm improvement activities through the use of high throughput, nondestructive sampling of seeds. A method of evaluating seeds...
US20100303861 Live Attenuated Vaccine Strain for Prevention of Tularemia  
The invention provides live attenuated avirulent strains of Francisella tularensis, as well as methods for their preparation and use in protecting a mammal against infection with F. tularensis and...
US20120076830 DIFFERENTIATION OF STEM CELLS WITH NANOPARTICLES  
A method for differentiating mesenchymal stem cells (MSCs) towards osteoblasts and other connective tissue using nanoparticles and electromagnetic stimulation Osteoinductive materials produced...
US20120088261 CELL LABELING AND IMAGING USING MULTIFUNCTIONAL PERFLUOROCARBON NANOEMULSION  
The present invention relates to cell labeling and imaging using a multifunctional perfluorocarbon (PFC) nanoemulsion. In particular, the perfluorocarbon nanoemulsion containing optical...
US20140343051 METHODS TO MODULATE ACUTE MYELOID LEUKEMIA STEM/PROGENITOR CELL EXPANSION AND/OR DIFFERENTIATION  
Novel methods for modulating acute myeloid leukemia stem/progenitor cell expansion and/or differentiation are disclosed. These methods are based on the use of aryl hydrocarbon receptor (AhR)...
US20150140013 MODULATION OF ASYMMETRIC PROLIFERATION  
Provided herein are methods and compositions related to modulation of the rate of asymmetric proliferation of cancer cells. In some embodiments, the methods described herein relate to the...
US20130337488 Method and System for Measuring the Pharmacokinetics of Liposomal Curcumin and its Metabolite Tetrahydrocurcumin  
The present invention includes a stabilized curcumin composition. The composition includes a curcumin composition and a phosphate composition, wherein the phosphate composition is non-buffering...
US20130071872 DEVICE AND METHOD FOR SINGLE-USED MATRIX SAMPLING  
A single-used matrix sampling device for the single-used, disposable or autoclavble packed-bed bioreactor is provided herein. The present invention includes a tube means and a matrix collecting...
US20120141434 Methods for Selecting Expanded Stem Cell Populations  
A method and criteria are provided for selecting expanded hematopoietic stem cell populations for allogenic transplantation, the selected cell populations having high probability of engraftment...
US20130149539 TUNED MULTIFUNCTIONAL MAGNETIC NANOPARTICLES FOR BIOMEDICINE  
Magnetic nanoparticles and related devices and methods are described. Compositions and methods can include magnetic nanoparticles having a narrow size distribution for use in diagnostics and...
US20120093774 AUXOTROPHIC RECOMBINANT BCG STRAIN PASTEUR AND USE THEREOF IN THE CONTROL OF HUMAN INFECTIONS CAUSED BY PARASITES  
The present invention relates to a vaccinal strain of recombinant BCG Mycobacterium bovis expressing the Schistossoma mansoni Sm14 protein (BCG Pasteur ΔleuD/pΔK410-hsp60*-Sm14). The vaccinal...
US20150093772 METHOD FOR EVALUATING COSMETIC  
It is an object of the invention to provide a method for evaluating cosmetics that allows development of cosmetics that can contribute to beautiful healthy skin. The object is achieved by a method...
US20120045789 Method for Screening of Antiviral Agents  
A method for screening for an antiviral agent capable of blocking a viral viroporin by determining whether a test agent can rescue expression of a fragment of a viral viroporin in a Single Protein...
US20110275110 METHOD FOR ISOLATING OR COUNTING MICROORGANISMS ON AN AGAR CULTURE MEDIUM  
The invention relates to a method for isolating microorganisms on an agar culture medium, including the steps of: depositing, on said agar culture medium, a predetermined amount of a sample to be...
US20130260404 FLUORESCENT LABELING OF LIVING CELLS  
Latent fluorescent tags, including compounds of Formula I, methods of making latent fluorescent tags, and methods of fluorescently labeling living cells are provided. The compounds of Formula I...
US20150147770 EMBRYO QUALITY ASSESSMENT BASED ON BLASTOCYST DEVELOPMENT  
The present invention relates to a method and to a system for selecting embryos for in vitro fertilization based on observed cell kinetics and cell morphology. One embodiment of the invention...
US20110287982 CELL CULTURE DEVICE  
The invention relates to the field of cell and tissue culture. In particular, the invention relates to devices for cell culture. A device for cell culture, according to the invention comprises (i)...
US20150135370 METHODS AND COMPOSITIONS FOR ENHANCED FORAGE QUALITY  
The invention provides a method to select an alfalfa plant with enhanced feed value and increased flexibility in management either to increase quality of forage provided or to enhance biomass...
US20120021064 COMPOSITIONS FOR BOWEL PREPARATION AND METHODS OF USE THEREOF  
The present invention relates to formulations and kits for gastrointestinal cleansing and to therapeutic methods thereof.
US20120165340 PTEN PHOSPHORYLATION-DRIVEN RESISTANCE TO CANCER TREATMENT AND ALTERED PATIENT PROGNOSIS  
Indicators that can guide clinical decisions in cancer, particularly posttranslational modification of proteins which result in altered prognosis and differential sensitivity to targeted cancer...
US20150225684 PHOTOBIOREACTOR  
A method for non-invasive growth measurement of organisms in an apparatus for growing and harvesting organisms or substances derived from such organisms. The organisms are comprised in an aqueous...
US20110195854 DETECTING AND MONITORING INFLAMMATORY NEUROPATHY  
The invention relates to detection and/or monitoring of inflammatory neuropathy using markers that specifically indicate the presence of inflammatory neuropathy, for example, allograft...
US20130017180 PLATELET RICH PLASMA FORMULATIONS  
Compositions for platelet rich plasma (PRP) and neutrophil-depleted PRP are provided. Methods for treating ischemia damaged tissues by delivering a PRP composition, in some embodiments a...
US20150017134 EMT-INDUCING TRANSCRIPTION FACTORS COOPERATE WITH SOX9  
In some aspects, compositions and methods useful for generating stem cells from epithelial cells are disclosed.
US20120225073 Isolation and Use of Melanoma Cancer Stem Cells  
A set of markers for melanoma cancer stem cells are provided. The cells can be prospectively isolated or identified from primary tumor samples, and possess the unique properties of cancer stem...
US20110311505 Photosensitive Aminoacid-Monomer Linkage and Bioconjugation Applications in Life Sciences and Biotechnology  
This invention is related to preparation of photosensitive ruthenium based aminoacid monomers and oligomers, aminoacid monomer-protein cross-linking using photo sensitat ion and conjugation on...
US20100330143 MODIFIED MACROMOLECULES AND METHODS OF MAKING AND USING THEREOF  
Described herein are composites produced by reacting a first thiolated macromolecule with at least one compound having at least one thiol-reactive electrophilic functional group. The methods...
US20150104821 Device and Method for Sorting and Labeling of Biological Systems based on the Ionic-Electric Dynamics  
The present invention relates to a method and a device for creating digital copies of the ionic-electric dynamics of cells or cell compartments, such as organisms, or an at least partly...
US20140087415 EMBRYO QUALITY ASSESSMENT BASED ON BLASTOMERE CLEAVAGE AND MORPHOLOGY  
The present invention relates to a method and to a system for selecting embryos for in vitro fertilization based on the timing, and duration of observed cell cleavages and associated cell...
US20110318367 NOVEL TARGETS FOR TREATMENT OF HYPERCHOLESTEROLEMIA  
In certain embodiments this invention this invention pertains to the discovery that inhibition of myosin light chain interacting protein (Mylip) can mitigate one or more symptoms of...