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US20110275101 METHOD FOR USING DIVISION ARRESTED CELLS IN SCREENING ASSAYS  
Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal...
US20110111434 COLON STEM CELLS ASSOCIATED WITH COLITISAND COLORECTAL CANCER AND METHODS OF USE  
The disclosure provides methods of isolating and propagating self-renewing colonic stem/progenitor cells (CS/PCs) that express aldehyde dehydrogenase (ALDH1), from colon cancer and colitis...
US20130217060 METHOD FOR THE PRODUCTION OF 1-BUTANOL  
A method for the production of 1-butanol by fermentation using a microbial production host is disclosed. The method employs a reduction in temperature during the fermentation process that results...
US20140134137 Use of Stem Cells to Reduce Leukocyte Extravasation  
The invention is generally directed to reducing inflammation by means of cells that secrete factors that reduce leukocyte extravasation. Specifically, the invention is directed to methods using...
US20130143955 Cyclic di-GMP-II Riboswitches, Motifs, and Compounds, and Methods for Their Use  
Disclosed are compositions and methods involving cyclic di-GMP—responsive Riboswitches and cyclic di-GMP-II motifs.
US20150240194 Microfluidic System for Reproducing Functional Units of Tissues and Organs In Vitro  
A microfluidic system for generating compartmentalized microenvironments of tissues and organs in vitro and for independently perfusing the compartments. A microfluidic device that includes at...
US20120315662 METHOD FOR THE EARLY DETECTION OF HIGH-GRADE PELVIC SEROUS CANCER  
A method for early detection of high-grade pelvic serous cancers, comprising acquiring fallopian tube cells in vivo by exfoliative cytology, and examining the acquired cells for precursors of...
US20110039282 METHOD OF DETECTING CALCIFYING NANOPARTICLES AND SUSCEPTIBILITY TO CALCIFYING NANOPARTICLE INFORMATION  
A method of measuring the susceptibility of a subject to calcifying nanoparticle formation is disclosed. The method can include obtaining a cell culture comprising peripheral blood mononuclear...
US20120282646 METHOD FOR ACTIVATING A NATURAL KILLER CELL BY ADJUSTING THE EXPRESSION OF THE SOCS2 GENE  
The present invention relates to a method for activating natural killer cells (NK cells), and more particularly, to a method for enhancing the cytotoxicity of natural killer cells by inducing the...
US20150241443 MASS SPECTROMETRIC QUANTITATION  
Provided is a method of assaying for an analyte, including combining a test sample having the analyte, with a calibration sample having at least two different aliquots of the analyte, each aliquot...
US20120258473 METHOD OF COLLECTING SPECIMEN AND METHOD OF DIAGNOSING SUBJECT TO DETECT UPPER DIGESTIVE SYSTEM DISEASE  
A method of collecting a specimen of the present invention is used in detecting upper digestive system disease. The method of collecting a specimen includes: a step of positioning sampling...
US20110300548 GDF15 AS MOLECULAR TOOL TO MONITOR AND ENHANCE PHENOTYPIC STABILITY OF ARTICULAR CHONDROCYTES  
The present invention relates to GDF15 as a molecular marker in in vitro assays determining phenotypic stability of articular chondrocytes and predicting the outcome of chondrocyte transplantation.
US20120034641 BIOLOGICAL INFORMATION ACQUISITION METHOD  
A biological information acquisition method includes: measuring an amount of nicotinamide metabolite in a sample collectable from a living organism in a minimally invasive manner; and acquiring...
US20110275075 SOX MODULATORS IN THE TREATMENT OF ALOPECIA  
An in vitro method for screening candidate compounds for the preventive or curative treatment of alopecia is described. The method can include determining the capacity of a compound to modulate...
US20110104658 Synthetic Microfluidic Blood-Brain Barrier  
An apparatus and method for assaying blood-brain barrier properties for drug and drug delivery vehicle screening comprising of a microfluidic apparatus with gaps separating lumen and tissue space...
US20120122716 CELL LINE DERIVED FROM THE EPITHELIAL LINING OF THE HUMAN ENDOLYMPHATIC SAC IN THE INNER EAR  
In some embodiments, the invention relates to a stable, long-term human ES cell line. In other aspects, the invention relates to methods for establishing a stable long-term ES cell line and...
US20110117542 REAL TIME ELECTRONIC CELL SENSING SYSTEM AND APPLICATIONS FOR CYTOTOXICITY PROFILING AND COMPOUND ASSAYS  
The invention provides methods of investigating a mechanism of action of a compound, which includes providing a device for monitoring cell-substrate impedance; attaching the device to an impedance...
US20110158980 METHODS TO TREAT AND SCREEN FOR AGENTS TO TREAT OBESITY  
Described herein are methods for treating obesity or promoting weight loss using agents that alter pyruvate flux in an adipocyte. Methods are provided for administering an agent or combination of...
US20110262436 TREATMENT METHOD  
The present invention relates generally to the fields of molecular biology and growth factor regulation. More specifically, the invention relates to therapies for the treatment of pathological...
US20110126315 NOVEL SELECTION MARKER GENE AND USE THEREOF  
A DNA construct including a gene which is operably linked to a seed-specific promoter and which encodes a fusion protein of a seed protein and a fluorescent protein is used. This provides a...
US20130101991 MICROFLUIDIC ASSAY IN IDEALIZED MICROVASCULAR NETWORK FOR SELECTION AND OPTIMIZATION OF DRUG DELIVERY VEHICLES TO SIMULATED TUMORS  
An apparatus for assaying a tumor drug delivery vehicle and or drug can include an idealized microvascular network (IMN) of one or more interconnected idealized flow channels in fluid...
US20150056644 CONTINUOUS CULTURE APPARATUS WITH MOBILE VESSEL, ALLOWING SELECTION OF FITTER CELL VARIANTS AND PRODUCING A CULTURE IN A CONTINUOUS MANNER  
A method and device for growing plant, animal or stem cells in a continuous manner.
US20110142833 METHODS FOR TREATING AND PREVENTING FIBROSIS  
The present invention provides methods of screening for compositions useful for treating, ameliorating, or preventing fibrosis and/or fibrosis-associated conditions by measuring changes in the...
US20110111452 METHOD AND KIT FOR DIAGNOSIS OF MALE FERTILITY  
A method and kit are disclosed for the diagnosis of male fertility.
US20110256565 METHODS FOR DIAGNOSIS AND TREATMENT OF NEURODEGENERATIVE DISEASES OR DISORDERS  
The present invention provides methods that are useful for the diagnosis of neurodegenerative disease or disorder and for the screening of compounds or therapeutic agents for treating a...
US20140325709 PROCESS FOR THE PRODUCTION OF FINE CHEMICALS  
The present invention relates to a process for the production of fine chemicals in a microorganism, a plant cell, a plant, a plant tissue or in one or more parts thereof. The present invention...
US20130210057 USE OF LABEL-FREE BIOSENSORS TO UNDERSTAND AND IDENTIFY TREATMENT FOR CANCER  
The disclosure relates to methods of using dynamic mass redistribution data obtained from cancer cells cultured on waveguide grating biosensors in the presence of agonists and in the presence of...
US20090239254 Functional pigmented skin equivalent  
An in vitro skin equivalent includes at least one epidermis equivalent and at least one dermis equivalent, and further includes melanocytes constitutively producing melanin and fibroblasts.
US20130309659 CELL CULTURING FORMULATION AND CULTURING AND QUANTIFICATION METHOD OF CD140B+ CELLS THEREOF  
The present invention discloses a cell culturing formulation and a culturing and quantification method of CD140b+ cells thereof. The cell culturing formulation is applicable for inducing the...
US20130029370 System for Purifying Certain Cell Populations in Blood or Bone Marrow by Depleting Others  
An apparatus and method for purifying and harvesting certain cell populations in blood or bone marrow by depleting at least one of red blood cells, granulocytes, or platelets from a sample...
US20140349328 Micro-Sampling for Aquatic Chemical Analysis  
The current invention describes in vivo and vitro (cultured) sampling technologies that allow direct temporal and spatial sampling from living ecosystems such as those associated with marine...
US20120283120 SCREENING METHOD  
The present invention provides a novel variant androgen receptor (ARaiv) lacking ligand binding domain, a nucleic acid encoding the same and use thereof. That is, the present invention provides a...
US20140186838 MOLECULAR FLUX RATES THROUGH CRITICAL PATHWAYS MEASURED BY STABLE ISOTOPE LABELING IN VIVO, AS BIOMARKERS OF DRUG ACTION AND DISEASE ACTIVITY  
The methods described herein enable the evaluation of compounds on subjects to assess their therapeutic efficacy or toxic effects. The target of analysis is the underlying biochemical process or...
US20130273533 MOLECULAR FLUX RATES THROUGH CRITICAL PATHWAYS MEASURED BY STABLE ISOTOPE LABELING IN VIVO, AS BIOMARKERS OF DRUG ACTION AND DISEASE ACTIVITY  
The methods described herein enable the evaluation of compounds on subjects to assess their therapeutic efficacy or toxic effects. The target of analysis is the underlying biochemical process or...
US20110269797 ANLN PROTEIN AS AN ENDOCRINE TREATMENT PREDICTIVE FACTOR  
The present invention provides methods, uses and means for breast cancer prognostics and treatment prediction. Provided methods comprises the steps of: providing a sample earlier obtained from a...
US20110033865 NOVEL METHOD FOR DIAGNOSING PREGNANCY-RELATED COMPLICATIONS  
A method for diagnosing pregnancy-related complications in a pregnant woman is provided. The method includes the following steps: (a) determining the level of Placental Protein 17 (PP17) in a...
US20150209407 METHODS FOR THE TREATMENT AND PREVENTION OF OSTEOPOROSIS AND BONE-RELATED DISEASES  
The present disclosure is directed to the identification that R-Spondin-1 (RSpo1) acts as a positive regulator of bone formation. Accordingly, the presently disclosed subject matter provides...
US20110091869 METHOD FOR CULTURE OF STEM CELL  
The present invention enables efficient suspension culture of stem cells in a serum-free medium by comprising a step for quickly forming a homogenous aggregate of stem cells, and provides a method...
US20150065389 MULTI-WELL MICROPATTERNING BY ABLATION  
The present invention is drawn to the generation of micropatterns of biomolecules and cells on standard laboratory materials through selective ablation of a physisorbed biomolecule with oxygen...
US20110027234 METHODS FOR IDENTIFICATION AND SELECTION OF HUMAN EMBRYONIC STEM CELL DERIVED CELLS  
A nucleic acid construct is disclosed, the nucleic acid comprising a polynucleotide comprising a nucleic acid sequence encoding a detectable expression product, the nucleic acid sequence being...
US20100311095 ASSESSMENT OF PHYSIOLOGICAL CONDITIONS  
The present invention relates to a method for assessing in vitro the balance and the overall dynamics of a physiological condition, wherein a) a first biochemical marker representing a first...
US20120231470 METHODS AND SYSTEMS ASSOCIATED WITH DETECTION OF FATTY ACID ELONGATION IN A CELL  
Methods and systems to identify compounds capable of altering a fatty acid elongation pathway and for identifying conditions under which fatty acids elongation can occur in a cell are described....
US20130059323 Detection of Overtraining Syndrome in an Individual  
The onset of or the existence of overtraining syndrome in an individual is detected by a method which comprises a) contacting leucocytes in, or obtained from, a blood sample provided by the...
US20110201669 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF CANCER  
The present invention relates to the diagnosis and treatment of cancer, and in particular breast cancer. Specifically, in some embodiments the invention relates to methods of diagnosing cancer,...
US20130171680 CHIMERIC AVIAN-BASED SCREENING SYSTEM CONTAINING MAMMALIAN GRAFTS  
The present invention relates to animal model systems comprising a chimera between an avian embryo and a mammalian organism. Specifically, chimeric model systems comprising normal, diseased or...
US20120077705 Methods for Identifying Autophagy Inducing Compounds  
This invention pertains to screening methods for identifying autophagy inducing compounds.
US20140314675 CANCER STEM CELL ISOLATION  
An objective of the present invention is to provide: a cancer stem cell isolated using a cell marker; a substantively homogeneous cancer stem cell population including said cancer stem cell; and a...
US20110217721 WATER SOLUBLE FLUORESCENT QUANTUM CARBON DOTS  
The present invention relates to the water soluble self fluorescent quantum carbon dots (C-dots). These C-dots are isolated from carbon soot in one embodiment a wax soot solvent washed and...
US20110111392 INTEGRATED ENHANCED CHEMILUMINESCENCE BIOSENSORS  
A method and apparatus for determining the concentration of an analyte in a sample is provided. This method involves combining enhanced chemiluminescence with microchip capillary electrophoresis...
US20110171232 METHODS OF TREATING AUTOIMMUNE DISEASES CAUSED BY SMALL INTESTINAL BACTERIAL OVERGROWTH  
Disclosed is a method of diagnosing autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, which involves detecting the presence of small intestinal bacterial overgrowth...