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US20140274912 METHODS OF CELL CULTURE  
Polypeptide preparations having target levels of glycans, and methods of producing such polypeptide preparations using putrescine, are described.
US20140273057 METHODS OF CELL CULTURE  
Polypeptide preparations having target levels of glycans, and methods of producing such polypeptide preparations using DMSO, are described.
US20110275107 LONG WAVELENGTH ENGINEERED FLUORESCENT PROTEINS  
Engineered fluorescent proteins, nucleic acids encoding them and methods of use.
US20140273069 PREDICTING HUMAN DEVELOPMENTAL TOXICITY OF PHARMACEUTICALS USING HUMAN STEM-LIKE CELLS AND METABOLOMICS  
The invention provides biomarker profiles of metabolites and methods for screening chemical compounds including pharmaceutical agents, lead and candidate drug compounds and other chemicals using...
US20110300569 DATA ANALYSIS OF IMPEDANCE-BASED CARDIOMYOCYTE-BEATING SIGNALS AS DETECTED ON REAL-TIME CELL ANALYSIS (RTCA) CARDIO INSTRUMENTS  
A method of determining one or more beating parameters for use in cardiomyocyte beating analysis including: providing a cell analysis device including wells, each well including a sensor capable...
US20110030098 Glycosyltransferases, Polynucleotides Encoding These And Methods Of Use  
The invention provides method for producing a plant cell or plant with increased phlorizin or phloretin glycosyltransferase activity, the method comprising transformation of a plant cell or plant...
US20130273554 BIOLUMINESCENT PACKAGING  
Some embodiments provided herein relate to bioluminescent packaging, methods of making, and methods of sensing the state of a material, in some embodiments, light emitted by a bioluminescent...
US20140193380 Technologies, Methods, and Products of Small Molecule Directed Tissue and Organ Regeneration from Human Pluripotent Stem Cells  
Pluripotent human embryonic stem cells (hESCs) hold great potential for restoring tissue and organ function, which has been hindered by inefficiency and instability of generating desired cell...
US20120301437 Technologies, Methods, and Products of Small Molecule Directed Tissue and Organ Regeneration from Human Pluripotent Stem Cells  
Pluripotent human embryonic stem cells (hESCs) hold great potential for restoring tissue and organ function, which has been hindered by inefficiency and instability of generating desired cell...
US20130239239 LMCD1 CANCER MARKERS AND METHODS FOR THEIR USE  
The present invention provides LMCD1 cancer markers, and methods, compositions, and kits for their use. The invention also provides expression vectors, host cells, and transgenic animals...
US20110179504 Method For Coral Tissue Cultivation And Propagation  
This invention relates to a novel method of culturing coral tissues and polyps in vitro. Coral tissues obtained by the method of the invention may be maintained as heterotypic spheroid tissue...
US20110123454 Method for modulating appetite  
The present invention provides a method of modulating appetite and/or body weight in a subject, said method comprising administering to said subject an effective amount of a MIC-1-modulating...
US20110010800 PLANTS WITH INCREASED YIELD  
The present invention disclosed herein provides a method for producing a plant with increased yield as compared to a corresponding wild type plant comprising increasing or generating one or more...
US20100311683 CYTIDINE ANALOGS FOR TREATMENT OF MYELODYSPLASTIC SYNDROMES  
The present invention provides methods of treating a patient having a higher risk myelodysplastic syndrome, which comprises administering to a patient having a higher risk myelodysplastic syndrome...
US20130183661 STABILIZED LEUKOCYTES AND THEIR USE IN HIV-DIAGNOSIS AND THERAPY  
A method of producing extremely stable leukocytes from human blood samples which are stable for long period of time under extraordinary temperature conditions. The method also relates to producing...
US20140363840 Method Of Determining The Viability Of At Least One Cell  
This disclosure provides a method of determining the viability of at least one cell via quantification of nicotinamide adenine dinucleotide (phosphate) (NAD(P)H), flavin adenine dinucleotide...
US20150246146 METHODS AND COMPOSITIONS FOR ENZYME-MEDIATED SITE-SPECIFIC RADIOLABELING OF GLYCOPROTEINS  
Provided herein are methods, compositions and kits for use in the site-specific labeling of glycoproteins comprising a combination of enzyme-mediated incorporation of modified sugars comprising a...
US20130059325 ISOLATED POPULATIONS OF ADULT RENAL CELLS AND METHODS OF ISOLATING AND USING SAME  
A method of generating a nephrospheroid is disclosed. The method comprises culturing human adult kidney cells in a culture medium under non-adherent conditions. Uses thereof and other renal cell...
US20130123135 Methods To Identify Modulators of TAS2R48 Receptors  
Disclosed are compounds that activate the human G-protein coupled receptor TAS2R48, and methods of using these compounds for identifying compounds that modulate the response of the TAS2R48...
US20110129865 METHOD FOR MARKING MATERIALS  
The invention relates to a marking system for marking objects wherein said system comprises a microparticle comprising a cross-linked polymer and a marker component wherein the release of said...
US20130344530 METHOD FOR SCREENING SUBSTANCE RELATING TO ENDOPLASMIC RETICULUM STRESS PARTICIPATING IN ONSET OF DIABETES  
An object of the present invention is to provide a system for evaluating activation of the pathway mediated by ATF6. More specifically, an object of the present invention is to provide a method...
US20100317047 Biomarkers of Hemorrhagic Shock  
Methods for the use of claudin-3 as a biomarker for diagnosis and prognosis, and for monitoring the efficacy of treatment, in hemorrhagic shock (HS).
US20150126396 Method for Identification, Selection and Analysis of Tumour Cells  
The present invention relates to a method for the diagnosis of tumoural conditions and/or of the corresponding state of advance, wherein a sample from a patient comprising at least one tumour cell...
US20120244545 METHOD FOR SCREENING ACTIVE AGENTS THAT STIMULATE THE EXPRESSION OF CERT TO IMPROVE THE SKIN'S BARRIER FUNCTION  
A method for screening an active agent intended for preventing or combating the cutaneous signs resulting from a non-pathological impairment of barrier function, which includes the selection of...
US20130252838 TARGET FOR BREAST CANCER THEREAPY AND/OR DIAGNOSIS  
The present invention relates to breast cancer and methods for identifying therapeutics and diagnosis. In general, methods for identifying therapeutic agents directed to calcium flow are...
US20110223157 METHODS FOR THE TREATMENT OF NON-HODGKIN'S LYMPHOMAS USING LENALIDOMIDE, AND GENE AND PROTEIN BIOMARKERS AS A PREDICTOR  
Methods of treating or managing specific cancers, including non-Hodgkin's lymphoma, by the administration of 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-d ione are disclosed....
US20110189716 METHOD FOR ANALYZING COLLAGENOUS TISSUES FOR THE DETECTION AND DIAGNOSIS OF BONE DISEASE  
Methods and systems for diagnosing a bone disease related to collagen pathology in a subject are provided. These include providing a bone sample from the subject and determining a quantitative...
US20110009279 Methods of Diagnosing Non-Alcoholic Steatohepatitis (NASH)  
Non-invasive methods for detecting non-alcoholic fatty liver disease (NAFLD) and identifying the presence or absence of non-alcoholic steatohepatitis (NASH) in a subject utilize one or more...
US20110086022 Methods for diagnosing and treating neuroendocrine cancer  
The present invention relates to a method for diagnosing neuroendocrine cancers via detecting the presence of N-methyl D-asparate-associated (NMDA) glutamate receptors type 1 and/or type 2....
US20110014202 Methods for Diagnosing and Treating Neuroendocrine Cancer  
The present invention relates to a method for diagnosing neuroendocrine cancers via detecting the presence of N-methyl D-asparate-associated (NMDA) glutamate receptors type 1 and/or type 2....
US20110035814 COOPERATING ONCOGENES IN CANCER  
This invention provides methods of diagnosis, drug screening, and treatment based on the discovery that cIAP1 and Yap are co-amplified oncogenes that cooperate to contribute to oncogenesis and...
US20110230442 NA CHANNELS, DISEASE, AND RELATED ASSAYS AND COMPOSITIONS  
Disclosed are molecules and their synthesis, for use in blocking gated ion channels such as voltage-gated sodium channels (VGSCs) and prostate voltage sodium channels (PVSCs). These inhibitors...
US20150093334 Vault and Vault like Carrier Molecules  
A method of using vaults as carrier molecules to deliver one or more than one substance to an organism, or to a specific tissue or to specific cells, or to an environmental medium. A vault-like...
US20110191873 Methods of Protein Destabilization and Uses Thereof  
This invention is directed towards methods of destabilizing proteins in living cells, and their use for the development of novel assays. In one embodiment, the invention comprises the use of...
US20120171717 METHOD OF SELECTING SAFE PLURIPOTENT STEM CELLS  
Provided is a method of selecting highly safe pluripotent stem cells that do not exhibit differentiation resistance, comprising the steps of (1) inducing a pluripotent stem cell to differentiate,...
US20120015393 ENDOGENOUS AUTO-FLUORESCENT BIOLOGICAL MARKERS FOR ASSESSING A BIOLOGICAL PARAMETER OF A CELL  
The present application relates to the use of endogenous fluorescent biological markers to determine a biological parameter of a cell in a liquid. The methods provided herein provide accurate...
US20130259847 INTERROGATORY CELL-BASED ASSAYS AND USES THEREOF  
Described herein is a discovery Platform Technology for analyzing a biological system or process (e.g., a disease condition, such as cancer) via model building
US20110160594 Method for Testing Substances or Substance Mixtures and the Use Thereof  
The present invention relates to a method for testing a substance or a substance mixture and the use thereof for identifying and/or characterizing the mode of action of the substance or the...
US20110281743 SYSTEMS AND METHODS FOR ISOLATING CELLS IN CELL COLONIES IN CULTURE  
Selecting and propagating a cell colony of interest from among a plurality of cell colonies carried on a common substrate in culture is carried out by: (a) selecting a cell colony of interest from...
US20100329982 PARTICLES WITH INDUCIBLE CHANGE OF SHAPE  
The invention relates to particles which exhibit a stimulable shape change and allow control of their uptake in active cells. The particles can be used as carrier systems for bioactive molecules...
US20120172581 PROCESS FOR THE IDENTIFICATION OF COMPOUNDS FOR TREATING CANCER  
Process for the identification of compounds for treating cancer. The invention relates to a method for identifying candidate compounds for use as therapeutic agents for the treatment of cancer,...
US20150253306 MITOCHONDRIAL TOXICITY TEST  
A novel method useful in drug screening. The method is useful for testing effects of substances on the mitochondria, notably toxic or beneficial effects of drug substances or candidate drug...
US20110244505 Method for In Vitro Blood Testing  
Method for determining the presence of a malady in a patient by measuring the degree of reaction of individual types of white blood cells (basophils, eosinophils, neutrophils, monocytes and...
US20150072368 TRANSCRIPTION UNITS AND THE USE THEREOF IN EXPRESSION VECTORS  
Novel transcription units that may be used in expression vectors. The transcription unit allow antibodies to be produced whose gain in productivity is not linked to a particular antigenic target...
US20110091460 RECEPTOR-TARGETING REAGENTS  
The present disclosure features, inter alia, receptor-targeting reagents (e.g., immunotoxic receptor-targeting reagents), which are useful in, e.g., methods of binding a receptor-targeting reagent...
US20140127735 CHARACTERIZATION OF N-GLYCAN MIXTURES BY NUCLEAR MAGNETIC RESONANCE  
The present disclosure provides nuclear magnetic resonance (NMR) methods for characterizing mixtures of N-linked glycans. Without limitation, methods of the present disclosure may be useful in...
US20110294874 DIAGNOSIS AND THERAPY OF ORGAN DYSFUNCTION USING SPHINGANINE-1-PHOSPHATE  
The invention relates to the treatment and diagnosis of organ dysfunction caused by ischemia reperfusion injury. In particular, the invention relates to sphinganine-1-phosphate, a sphingolipid...
US20110217700 METHODS OF SEED BREEDING USING HIGH THROUGHPUT NONDESTRUCTIVE SEED SAMPLING  
The present invention provides for novel methods to facilitate germplasm improvement activities through the use of high throughput, nondestructive sampling of seeds. A method for analyzing a...
US20150198615 METHODS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING X-RAY FLUORESCENCE  
The present invention includes a method and apparatus for measuring the transport of analytes through a cell barrier.
US20110008823 TOXICITY SCREENING METHODS  
The present invention provides methods of determining a level of toxicity of a given compound based on in vitro assays. The present invention provides particular methods of determining...