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US20090317881 |
METABOLICALLY ENGINEERED CELLS FOR THE PRODUCTION OF PINOSYLVIN
A genetically engineered micro-organism having an operative metabolic pathway producing cinnamoyl-CoA and producing pinosylvin therefrom by the action of a stilbene synthase is used for pinosylvin...
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US20090311771 |
ARABINOSE-AND XYLOSE-FERMENTING SACCHAROMYCES CEREVISIAE STRAINS
The present invention relates to a S. cerevisiae strain expressing both arabinose and xylose utilization pathways, and in particular to a S. cerevisiae strain fermenting both arabinose and...
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US20090311253 |
Dual Variable Domain Immunoglobulins and Uses Thereof
The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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US20090311275 |
Carrier for targeting nerve cells
The present invention relates to a transport protein which can be obtained by modifying the heavy chain of the neurotoxin formed by Clostridium botulinum wherein (i) the protein binds...
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US20090305342 |
Solubilization and Purification of a Target Protein fused to a Mutant Maltose-Binding Protein
Methods and compositions are provided for increasing at least one of: (i) binding affinity of a target protein for a maltodextrin substrate and/or (ii) solubility of a target protein. The methods...
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US20090288337 |
METHYLBUTANOL AS AN ADVANCED BIOFUEL
This invention describes genes, metabolic pathways, microbial strains and methods to produce methyl butanol and other compounds of interest from renewable feedstocks.
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US20090286294 |
Methods and Compositions for Improving the Production of Fuels in Microorganisms
The invention relates to compositions, systems, and methods for producing fuels, such as ethanol and hydrogen, and related compounds. More specifically, compositions and methods are provided for...
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US20090280546 |
YEAST STRAIN FOR PRODUCTION OF FOUR CARBON ALCOHOLS
Yeast cells with a reduced general control response to amino acid starvation were found to have increased tolerance to butanol in the growth medium. The reduced response was engineered by genetic...
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US20090275097 |
PRIMARY ALCOHOL PRODUCING ORGANISMS
The invention provides a non-naturally occurring microbial organism having a microbial organism having at least one exogenous gene insertion and/or one or more gene disruptions that confer...
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US20090263880 |
MUTANT LUCIFERASE
An object of the present invention is to provide a mutant luciferase having luciferase activity with an altered emission spectrum. A specific amino acid residue(s) is substituted in a luciferase...
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US20090258794 |
APOPTOSIS METHODS, GENES AND PROTEINS
A W303a Saccharomyces cerevisiae yeast cell which contains a polynucleotide that encodes a functional Bax polypeptide under the control of a galactose-inducible promoter that is integrated at the...
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US20090253189 |
Lactic Acid-Producing Yeast Cells Having Nonfunctional L- or D-Lactate:Ferricytochrome C Oxidoreductase Cells
Yeast cells having an exogenous lactate dehydrogenase gene ae modified by reducing L- or D-lactate:ferricytochrome c oxidoreductase activity in the cell. This leads to reduced consumption of...
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US20090249516 |
Diacylglycerol acyltransferases from flax
The invention relates to isolated diacylglycerol acyltransferases and polynucleotide sequences encoding the DGAT enzymes; polynucleotide constructs, vectors and host cells incorporating the...
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US20090246857 |
STABLE RECOMBINANT YEASTS FOR FERMENTING XYLOSE TO ETHANOL
Described are recombinant yeast which ferment xylose to ethanol and which maintain their ability to do so when cultured for numerous generations in non-selective media. The preferred yeast contain...
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US20090246844 |
Methods for the production of ethanol
Embodiments of the present invention include methods for the production of ethanol, by a consolidated bioprocessing approach for the conversion of cellulosic material. According to some...
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US20090239262 |
Affinity Polypeptide for Purification of Recombinant Proteins
The present disclosure provides an affinity polypeptide for the purification of a recombinant biologically active protein or polypeptide. Further, the present disclosure provides a fusion...
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US20090239275 |
FERMENTIVE PRODUCTION OF FOUR CARBON ALCOHOLS
Methods for the fermentive production of four carbon alcohols are provided. Specifically, butanol, preferably 2-butanol is produced by the fermentive growth of a recombinant bacteria expressing a...
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US20090239274 |
Yeast and Method of Producing L-Lactic Acid
Yeast includes an introduced gene coding a Homo sapiens - or frog-derived L-lactate dehydrogenase. It is possible to produce lactic acid, which has a variety of applications, efficiently and more...
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US20090232801 |
Humanized Antibodies Which Bind To AB (1-42) Globulomer And Uses Thereof
The present invention relates to binding proteins and, in particular, humanized antibodies that may be used, for example, in the diagnosis, treatment and prevention of Alzheimer's Disease and...
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US20090233849 |
Recombinant Alpha-Fetoprotein, Method and Means for Preparation Thereof, Compositions on the Base Thereof and Use Thereof
The invention relates to the microbiological and medical industry, genetic engineering, biotechnology. A Saccharomyces cerevisiae yeast strain was obtained on the basis of constructing a...
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US20090226882 |
Method for Identifying Fungicidally Active Compounds that are Based on Ipp Isomerases
The invention relates to a method for identifying fungicides, to the use of fungal IPP isomerase for identifying fungicides, and to the use of inhibitors of the IPP isomerase as fungicides.
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US20090226991 |
YEAST ORGANISM PRODUCING ISOBUTANOL AT A HIGH YIELD
There is disclosed a method of producing isobutanol. In an embodiment, the method includes providing a microorganism transformed with an isobutanol producing pathway containing at least one...
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US20090226959 |
Production of modified glycoproteins having multiple antennary structures
The present invention relates to eukaryotic host cells, especially lower eukaryotic host cells, having modified oligosaccharides which may be modified further by heterologous expression of a set of...
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US20090209024 |
Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
The present invention relates to eukaryotic host cells having modified oligosaccharides which may be modified further by heterologous expression of a set of glycosyltransferases, sugar transporters...
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US20090203089 |
ISOLATED ALCOHOL DEHYDROGENASE ENZYMES AND USES THEREOF
Bacterial polynucleotides and polypeptides are provided in which the polypeptides have a dehydrogenase activity, such as an alcohol dehydrogenase (ADH) activity, an uronate, a...
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US20090202437 |
Therapeutic Use of Lpi, a Staphylococcal Lectin Pathway Inhibitor in Inflammatory diseases
The invention relates to nucleic acid molecules encoding (poly)peptides having LPI (Lectin Pathway Inhibitor) activity, to recombinant vectors harboring such molecules, and the host cells carrying...
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US20090186381 |
CELLULASE VARIANTS WITH REDUCED INHIBITION BY GLUCOSE
A Family 6 cellulase variant enzyme comprising one or more than one amino acid substitution selected from a basic, polar or non-polar amino acid at position 103, a valine or isoleucine at position...
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US20090181041 |
Production of proteins carrying oligomannose or human-like glycans in yeast and methods of use thereof
Cell lines having genetically modified glycosylation pathways that allow them to carry out a sequence of enzymatic reactions, which mimic the processing of glycoproteins in humans, have been...
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US20090176285 |
Compositions and Methods for Enhancing Glycerol Utilization
A glycerol utilizing cell and a method for the production of glycerol-derived target compounds are provided. The glycerol utilizing cell may comprise a glycerol metabolizing system or a glycerol...
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US20090162896 |
Production of Recombinant Collagen Like Proteins
The present invention is directed to a yeast cell for producing a recombinant collagen like protein. The present invention is further directed to a kit of parts or a co-expression system for use in...
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US20090162893 |
Alcohol dehydrogenase for the stereoselective production of hydroxy compounds
The invention relates to a DNA molecule encoding an NADP-dependent alcohol dehydrogenase, to a vector containing at least one copy of the DNA sequence, and to prokaryotic or eukaryotic host cells...
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US20090156497 |
Non-cytotoxic PAP mutants
Disclosed are PAP mutants that are less toxic than wild type PAP and that exhibit depurination activity. Also disclosed are transgenic plants that produce the PAP mutants, and methods for preparing...
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US20090155874 |
METHOD FOR PRODUCING TERPENES AND MEP-TRANSFORMED MICROORGANISMS THEREFORE
The present invention relates to a microorganism capable of producing a terpene of choice. The microorganism expresses a heterologous pathway for the formation of isoprene units and, preferably, a...
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US20090155866 |
METHODS FOR THE SYNTHESIS OF OLEFINS AND DERIVATIVES
The invention provides a method of producing acrylic acid. The method includes contacting fumaric acid with a sufficient amount of ethylene in the presence of a cross-metathesis transformation...
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US20090143308 |
Yeast membrane protein expression system and its application in drug screening
The invention relates to an in vitro cell based expression system for overexpressing heterologous pump proteins associated with drug resistance into the membrane of the host cell for drug screening...
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US20090130255 |
Catalase Gene and Use Thereof
The present invention relates to a gene encoding a catalase and use thereof, in particular, a brewery yeast having high sulfite-producing capability, alcoholic beverages produced with said yeast,...
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US20090123967 |
Modified spider silk proteins
The present invention is directed to a method of modifying a spider silk protein and a spider silk protein obtainable by said method. The invention further pertains to a nucleic acid sequence...
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US20090117227 |
GENE ENCODING TREHALOSE-6-PHOSPHATE PHOSPHATASE AND USE THEREOF
The present invention relates to a gene encoding trehalose-6-phosphate phosphatase and use thereof, in particular, a yeast for practical use with superior resistance property to dryness and/or...
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US20090098561 |
Higher-order cellular information processing devices
The invention provides various signal processing devices for integrating two or more biological signals (e.g., the presence, absence or concentration of specific ligands, etc.) to generate a status...
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US20090087515 |
GENE ENCODING ACETOLACTATE SYNTHASE AND USE THEREOF
The present invention relates to an acetolactate synthase gene and use thereof, in particular, a brewery yeast for producing alcoholic beverages with superior flavor, alcoholic beverages produced...
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US20090087892 |
METHODS FOR PRODUCING MUTANT MICROBES USEFUL FOR PRECIOUS METAL AND BIOENERGY PRODUCTION
A mutant microbe that generates trace amounts of gold on silver, and uses of the mutant microbe for producing and recovering precious metals and for producing biofuels and oil products from biomass...
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US20090081734 |
Arabinitol Dehydrogenases from Neurospora crassa
Stable and active arabinitol dehydrogenases (LAD) from Neurospora crassa and mutants thereof are disclosed. Arabinitol dehydrogenases are useful in the production of xylitol and ethanol from an...
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US20090074734 |
MICROBIAL INTESTINAL DELIVERY OF OBESITY RELATED PEPTIDES
Microbial delivery of obesity related peptides is disclosed. Genetically modified yeasts and/or lactic acid bacteria are described for the delivery of neuropeptides and/or peptide hormones that...
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US20090074925 |
ENZYMES
The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding to Citrobacter freundii phytase...
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US20090075900 |
Therapeutic agent for motor neuron disease
An object of the present invention is to provide an agent effective for the treatment and/or prevention of motor neuron disease such as amyotrophic lateral sclerosis (ALS). The present invention...
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US20090068704 |
UTILIZATION OF STARCH FOR BIOLOGICAL PRODUCTION BY FERMENTATION
This invention relates to a method for utilizing less purified starch in fermentation processes. One example is a recombinant E. coli containing a exogenous extracellular isoamylase activity that...
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US20090053797 |
GENETICALLY MODIFIED HOST CELLS AND USE OF SAME FOR PRODUCING ISOPRENOID COMPOUNDS
The present invention provides genetically modified eukaryotic host cells exhibiting increased activity levels of one or more enzymes that generate precursors to be utilized by the mevalonate...
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US20090053782 |
YEAST CELLS HAVING DISRUPTED PATHWAY FROM DIHYDROXYACETONE PHOSPHATE TO GLYCEROL
Yeast cells are genetically modified to disrupt a native metabolic pathway from dihydroxyacetone to glycerol. In certain aspects, the yeast cell is of the genera Kluyueromyces, Candida or ...
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US20090053784 |
EXPRESSION OF AN ACTIVE CARRIER FROM XYLOSE IN GENETICALLY MODIFIED SACCHAROMYCES CEREVISAE
The present invention confers to the ferementative yeast Saccharomyces cerevisiae , genetically modified by insertion of a nucleic acid sequence encoding a xylose and a glucose active transporter,...
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US20090047708 |
HIGHLY PRODUCTIVE RECOMBINANT YEAST STRAINS WITH MODIFIED GALACTOSE-REGULATED TRANSCRIPTION
A recombinant yeast cell with modified galactose-regulated transcription, a use of such yeast cell, and products made using such yeast cell are disclosed. In such a recombinant yeast cell, a...
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