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US20090304752 |
HYPOALLERGENIC VARIANTS OF THE MAJOR ALLERGEN FROM BETULA VERRUCOSA POLLEN
The invention provides hypoallergenic variants of Bet v 1 major allergen from Betula verrucosa plant pollen and the use thereof for the preventive or therapeutic treatment of allergic diseases.
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US20090304637 |
RECOMBINANT MYCOBACTERIUM STRAIN EXPRESSING A MYCOBACTERIAL FAP PROTEIN UNDER THE CONTROL OF A PROMOTER ACTIVE UNDER HYPOXIA AND ITS APPLICATION FOR CANCER THERAPY
The invention relates to a recombinant vector comprising a mycobacterial FAP protein coding sequence under the transcriptional control of a promoter active under hypoxia conditions and its use for...
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US20090307788 |
RIBOZYME MEDIATED STABILIZATION OF POLYNUCLEOTIDES
The present invention relates to the production of novel, recombinant polynucleotides comprising the GIR1 ribozyme, or a variant thereof, vectors comprising such polynucleotides and recombinant...
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US20090305353 |
Mutant firefly luciferase, gene, recombinant vector, transformant, and method for production of mutant firefly luciferase
The present invention provides a mutant firefly luciferase consisting of a mutant amino acid sequence derived from the amino acid sequence of a wild-type firefly luciferase by at least substitution...
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US20090305369 |
DELETION MUTANTS FOR THE PRODUCTION OF ISOBUTANOL
An E. coli host strain was engineered wherein genes adhE, IdhA, frdB, and pfIB were disrupted and novel butanol dehydrogenase gene, sadB, from Achromobacter xylosoxidans, was added to produce...
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US20090306189 |
Methods for Controlling Pests Using Rnai
The present invention relates to methods for controlling pest infestation using double stranded RNA molecules. The invention provides methods for producing transgenic cells expressing the double...
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US20090298143 |
SECRETION OF FATTY ACIDS BY PHOTOSYNTHETIC MICROORGANISMS
Recombinant photosynthetic microorganisms that convert inorganic carbon to secreted fatty acids are described. Methods to recover the secreted fatty acids from the culture medium without the need...
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US20090300779 |
Cancer selective auxotrophs
Bacteria that are auxotrophic for at least two amino acids found in at least one tumor are effective anti tumor treatments, labeling agents, and vaccines against infection. Improved antitumor...
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US20090298151 |
HYDROGEN PRODUCING MICROORGANISM USEFUL FOR ENERGY GENERATION FROM DIVERSE CARBONACEOUS FEEDSTOCK
The disclosed invention relates to an isolated hydrogen gas producing microorganism, termed Enterobacter sp. SGT-T4™ and derivatives thereof. Compositions and methods comprising the disclosed...
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US20090297482 |
PROBIOTIC STRAIN AND ANTIMICROBIAL PEPTIDE DERIVED THEREFROM
The invention relates to a strain of Enterococcus mundtii having probiotic qualities. The strain of E. mundtii (ST4SA) produces an antimicrobial peptide which exhibits antimicrobial activity...
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US20090300794 |
Manipulation Of The Nitrogen Metabolism
The present invention relates to the manipulation of the nitrogen metabolism in photosynthetic active organisms, preferably in plants. In particular, the present invention relates to a process for...
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US20090297495 |
HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR IMPROVING PAPER STRENGTH
The invention provides hydrolases, polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides,...
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US20090298920 |
CHIMERIC TRANSFER RNA AND USE THEREOF FOR THE PRODUCTION OF RNA BY A CELL
The present invention relates to the use of a nucleic acid encoding a chimeric transfer RNA (tRNA), which chimeric tRNA originates from the modification of a tRNA by insertion of an RNA into the...
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US20090298135 |
Method for fermentative production of L-methionine
A microorganism strain suitable for fermentative production of L-methionine and preparable from a starting strain, which comprises increased activity of a yjeH gene product or of a gene product of...
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US20090298086 |
PLANT FARNESYLTRANSFERASES
This invention relates to an isolated nucleic acid fragment encoding a farnesyltransferase subunit. The invention also relates to the construction of a chimeric gene encoding all or a portion of...
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US20090298119 |
Genetically encoded coumarin amino acids
The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the coumarin unnatural amino acid L-(7-hydroxycoumarin-4-yl)ethylglycine into proteins...
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US20090298754 |
Hai-1 and hai-2 in cancer therapy
The invention relates to a novel therapeutic composition for treating cancer, and particularly prostrate and breast cancer, the composition comprises mixture of two hepatocyte growth factor...
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US20090298804 |
Novel Compounds and Methods for Their Production
The present invention relates to 15-desmethoxymacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies malaria, fungal infection, diseases of the central nervous...
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US20090298762 |
CONJUGATES OF BIOLOGICALLY ACTIVE PROTEINS HAVING A MODIFIED IN VIVO HALF-LIFE
Disclosed are biologically active protein conjugates that comprise a biologically active polypeptide coupled via a peptide bond to a polypeptide comprising from 2 to about 500 units of a repeating...
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US20090298108 |
Method for Identifying PDE11 Modulators
The invention relates to a novel GAF A domain-containing polypeptide, to the GAF A domain of a human phosphodiesterase 11 (PDE11) and to the adenylate cyclase catalytic domain. The use of said...
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US20090298167 |
INTERLEUKIN-21 RECEPTOR BINDING PROTEINS
The present invention provides binding proteins and antigen-binding fragments thereof that specifically bind to the human interleukin-21 receptor (IL-21R). The binding proteins can act as, e.g.,...
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US20090298137 |
MICROORGANISM AND PROCESS FOR THE PREPARATION OF L-METHIONINE
The present invention relates to microorganisms and processes for the efficient preparation of L-amino acids such as L-methionine. In particular, the present invention relates to microorganisms and...
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US20090298706 |
METHOD FOR CELL SURFACE DISPLAYING OF TARGET PROTEINS USING BACILLUS ANTHRACIS EXOSPORIUM
The present invention relates to a method for expressing a target protein on the surface of a microorganism using Bacillus anthracis exosporium protein. More particularly, to an expression vector...
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US20090293148 |
Improved Methods Controlling Gene Expression
The present invention is in the field of genetics, especially plant genetics, and provides agents capable of controlling gene expression. The present invention specifically provides sequences of...
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US20090291480 |
Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production
The present disclosure provides novel beta-alanine/alpha ketoglutarate aminotransferase nucleic acid and protein sequences having increased biological activity. Also provided are cells containing...
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US20090291469 |
Compositions and Methods for Producing Fermentation Products and Residuals
The present invention provides compositions and methods designed to increase value output of a fermentation reaction that yields a first product, intended for commercialization, such as ethanol,...
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US20090291455 |
Cynomolgus gp80 Receptor and Uses
Isolated polynucleotides encoding cynomolgus monkey gp80, polypeptides obtainable from expression of these polynucleotides, compositions, recombinant cells, methods of making and using these...
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US20090291471 |
Novel Beta-Galactoside Alpha 2,6-Sialyltransferase, Gene Coding For The Transferase And Process For Producing The Same
The present invention provides a novel β-galactoside-α2,6-sialyltransferase having high productivity and/or high activity, and a nucleic acid encoding the sialyltransferase. The present invention...
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US20090286291 |
BORRELIDIN-PRODUCING POLYKETIDE SYNTHASE AND ITS USE
The present invention relates to the biosynthesis of polyketides and derives from the cloning of nucleic acids encoding a polyketide synthase and other associated proteins involved in the synthesis...
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US20090285933 |
Product and Process
The present invention concerns a new α-galactosidase with transgalactosylating activity isolated from Bifidobacterium bifidum . The α-galactosidase is capable of converting mellibiose to...
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US20090285821 |
Campylobacter Pilus Protein, Compositions and Methods
The present disclosure provides coding and amino acid sequences for a Campylobacter jejuni pilus protein (and from other species as well). This protein, when administered to a human or animal,...
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US20090285750 |
AGENT, COMPOSITION AND METHOD
The present application relates to agents, compositions and methods for use in medicine. In particular, the application relates to an agent comprising a binding moiety capable of selectively...
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US20090286294 |
Methods and Compositions for Improving the Production of Fuels in Microorganisms
The invention relates to compositions, systems, and methods for producing fuels, such as ethanol and hydrogen, and related compounds. More specifically, compositions and methods are provided for...
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US20090286280 |
METHOD FOR ACHIEVING IMPROVED POLYPEPTIDE EXPRESSION
The present invention relates to methods of optimization of a protein coding sequences for expression in a given host cell. The methods apply genetic algorithms to optimise single codon fitness...
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US20090286244 |
Fluorescent Color Markers
The invention provides a yeast-enhanced red fluorescent protein. In an embodiment of the invention, the yeast-enhanced red fluorescent protein is monomeric and is expressible in Candida albicans ....
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US20090285805 |
Binding molecules
The present invention relates to the manufacture of a diverse repertoire of functional heavy chain-only antibodies that undergo affinity maturation, and uses thereof. The invention also relates to...
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US20090286303 |
PROCESS FOR PREPARING (2R,3S)-1,2-EPOXY-3-(PROTECTED) AMINO-4-SUBSTITUTED BUTANE AND INTERMEDIATES THEREOF
The present invention relates to a process for preparing (2R,3S)-1-halo-2-hydroxy-3-(protected)amino-4-substituted butane comprising contacting a mutagenized Rhodococcus erythropolis having ATCC...
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US20090285784 |
DSRNA As Insect Control Agent
The present invention concerns methods for controlling insect infestation via RNAi-mediated gene silencing, whereby the intact insect cell(s) are contacted with a double-stranded RNA from outside...
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US20090280104 |
COMPOSITIONS AND METHODS FOR INHIBITING SHIGA TOXIN AND SHIGA-LIKE TOXIN
The present invention provides compositions and methods for treating or preventing infection by shiga toxin producing bacteria.
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US20090280555 |
ENZYME TREATMENT OF FOODSTUFFS FOR CELIAC SPRUE
Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of...
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US20090282587 |
Rice promoters
The invention provides several promoters isolated from Oryza sativa , which promoters are capable of driving and/or regulating the expression of an operably linked nucleic acid in a plant. The...
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US20090280553 |
METHOD FOR DESIGNING MUTATED ENZYME, METHOD FOR PREPARING THE SAME, AND MUTATED ENZYME
It is intended to provide a novel method for improving an enzyme hydrolyzing an a-1,6-glycosidic linkage. A mutated enzyme is designed by specifying one or more amino acids selected from the group...
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US20090280141 |
Streptococcal Genes
Peptides derived from S. pneumoniae are identified as virulence determinants and may be useful in the preparation of vaccines for the treatment of infection. The peptides may be used as antigens...
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US20090280105 |
Novel Fungal Enzymes
This invention relates to novel enzymes and novel methods for producing the same. More specifically this invention relates to a variety of fungal enzymes. Nucleic acid molecules encoding such...
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US20090280125 |
Prion epitopes and methods of use thereof
Prion peptides comprising prion epitopes and fusions thereof, that display enhanced immunogenicity are described. Also described are methods of treating and diagnosing prion disease.
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US20090280527 |
Amylase variants
The present invention relates to variants of a parent α-amylase, which parent α-amylase (i) has an amino acid sequence selected from the amino acid sequences shown in SEQ ID No. 1, SEQ ID No. 2,...
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US20090280056 |
Antibodies and immunoconjugates and uses therefor
Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP- 1 antibodies and immunoconjugates thereof are provided.
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US20090275493 |
Novel Alkaline Protease from Bacillus Gibsonii and Washing and Cleaning Agents containing said Novel Alkaline Protease
A novel subtilisin-type alkaline protease from Bacillus gibsonii and to sufficiently related proteins and the derivatives thereof. Also, washing and cleaning agents comprising the novel...
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US20090274618 |
TADG-15: an extracellular serine protease overexpressed in carcinomas
The present invention provides DNA encoding a TADG-15 protein as well as a TADG-15 protein. Also provided is a vector capable of expressing the DNA of the present invention adapted for expression...
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US20090274701 |
CHLAMYDIA PNEUMONIAE POLYNUCLEOTIDES AND USES THEREOF
The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides of Chlamydia pneumoniae , such as cellular envelope polypeptides, which are secreted or...
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