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US20090300803 |
GENE CODING FOR ACETOLACTATE SYNTHASE
The present invention provides a gene coding for the following protein (a) or (b) showing a high level of resistance to PC herbicides or sulfonylurea herbicides: (a) a protein which consists of an...
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US20090300801 |
ISOLATED MENTHONE REDUCTASE AND NUCLEIC ACID MOLECULES ENCODING SAME
The present invention provides isolated menthone reductase proteins, isolated nucleic acid molecules encoding menthone reductase proteins, methods for expressing and isolating menthone reductase...
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US20090300799 |
PLANT GALACTINOL SYNTHASE HOMOLOGS
Isolated nucleic acid fragments encoding galactinol synthase are disclosed. Recombinant DNA construct(s) for use in altering expression of endogenous genes encoding galactinol synthase are also...
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US20090298146 |
Method of Producing Astaxanthin or Metabolic Product Thereof by Using Carotenoid Ketolase and Carotenoid Hydroxylase Genes
To provide a microorganism or a plant transformed with a β-ionone ring-4-ketolase gene and/or β-ionone ring-3-hydroxylase gene derived from Brevundimonas sp. strain SD-212. The β-ionone...
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US20090291888 |
MODULATORS OF TNF RECEPTOR ASSOCIATED FACTOR (TRAF), THEIR PREPARATION AND USE
A DNA sequence encoding a protein capable of binding to a tumor necrosis factor receptor-associated factor (TRAF) molecule, TRAF-binding proteins, their isoforms, analogs, fragments and derivatives...
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US20090286295 |
PROCESSING BIOMASS
Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems can use feedstock materials, such as...
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US20090286294 |
Methods and Compositions for Improving the Production of Fuels in Microorganisms
The invention relates to compositions, systems, and methods for producing fuels, such as ethanol and hydrogen, and related compounds. More specifically, compositions and methods are provided for...
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US20090286247 |
Novel nucleic acid base pair
A novel artificial nucleic acid base pair which is obtained by forming a selective base pair by introducing a group having steric hindrance (preferably a group having steric hindrance and static...
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US20090285933 |
Product and Process
The present invention concerns a new α-galactosidase with transgalactosylating activity isolated from Bifidobacterium bifidum . The α-galactosidase is capable of converting mellibiose to...
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US20090285803 |
ANTI-PirB ANTIBODIES
The present invention relates generally to neural development and neurological disorders. The invention specifically concerns identification of novel modulators of the myelin-associated inhibitory...
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US20090285801 |
Calcium-Sensing Receptor 2 (CaR2) and Methods for Using
The current disclosure provide a novel human calcium sensing receptor named CaR2 and the nucleotide sequence that encodes the receptor. The disclosure further provides antibodies specific for CaR2....
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US20090280536 |
EXPRESSION SYSTEM FOR PROTEINS
The invention provides a novel system for the tunable expression of nucleic acids encoding e.g., polypeptides such as recombinant proteins in prokaryotic systems. The system is based on the ability...
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US20090280138 |
PEPTIDE
The present invention relates to peptide epitopes of 5T4 antigen and their use in immunotherapy. In particular, the present invention relates to any one of the peptide epitopes as described herein...
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US20090280116 |
HUMANIZED ANTIBODIES AGAINST TL1A
Disclosed are humanized antibodies that bind specifically to the receptor TNF superfamily member 15 (TNFSF15), also known as TL1A. Methods of making and using the anti-TL1A antibodies are also...
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US20090275517 |
G-CSF POLYPEPTIDES AND USES THEREOF
The present invention relates to G-CSF polypeptides and their uses, particularly for therapeutic or prophylactic treatment in human subjects. The invention also relates to nucleic acids encoding...
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US20090275481 |
Anchored Transferrin Fusion Protein Libraries
Fusion proteins comprising a transferrin moiety, a stalk moiety, and cell wall linking member and peptide libraries thereof are disclosed. The present invention includes a method of screening...
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US20090275096 |
MICROORGANISMS FOR THE PRODUCTION OF METHACRYLIC ACID
The invention provides a non-naturally occurring microbial organism having a 2-hydroxyisobutyric acid, 3-hydroxyisobutyric acid or methacrylic acid pathway. The microbial organism contains at least...
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US20090275092 |
METHOD FOR PRODUCING 4-HYDROXY-L-ISOLEUCINE
A highly active L-isoleucine dioxygenase from Bacillus thuringiensis is provided. A method for manufacturing (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof by reacting L-isoleucine in an...
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US20090275083 |
ISOLATED PEPTIDES HAVING PHOSPHOLIPASE INHIBITORY ACTIVITY
The invention provides for isolated peptides having phospholipase inhibitory activity, polypeptides comprising phospholipase inhibitory activity and lipases capable of being inhibited by the...
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US20090274707 |
Anti-IL-12 Antibodies, Nucleic Acids Encoding Antibodies, and Methods of Production
Isolated anti-IL-12 antibodies, nucleic acids encoding antibodies or antibody portions, vectors, host cells, and methods of making are useful for production of antibody or portions for treating...
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US20090274692 |
CD37 IMMUNOTHERAPEUTIC AND COMBINATION WITH BIFUNCTIONAL CHEMOTHERAPEUTIC THEREOF
The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as...
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US20090270489 |
LONG-ACTING POLYPEPTIDES AND METHODS OF PRODUCING SAME
A polypeptide and polynucleotides encoding same comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a peptide-of-interest are disclosed. Pharmaceutical...
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US20090269852 |
Novel gene gms 01
The present invention relates to microorganisms genetically engineered to increase yield and/or efficiency of biomass production from a carbon source, such as e.g. glucose. Processes for generating...
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US20090269849 |
Bioreactor Apparatus
A bioreactor includes a fluid containment vessel and a rotating mixing element including radial inflow elements configured to direction fluid radially inwardly of the mixing element and axial out...
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US20090269820 |
Dna coding for polypeptide participating in biosynthesis of pladienolide
The present invention provides polypeptides that participate in the biosynthesis of the pladienolide macrolide compounds, DNA that encodes these polypeptides and variants of this DNA, transformants...
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US20090263403 |
MAMMALIAN CELL MEMBRANE PROTEINS; RELATED REAGENTS
The purification and isolation of various genes which encode mammalian cell surface polypeptides. Nucleic acids, proteins, antibodies, and other reagents useful in modulating development of cells,...
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US20090258832 |
Cytokines and Cytokine Receptors With Reduced Immunocencity
The present invention provides methods for the identification of CD4 + T-cell epitopes in the sequences of various proteins, namely, human cytokines and cytokine receptors, as well as the...
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US20090258407 |
TEMPERATURE TRANSFER DEVICES
A portable temperature transfer device for transferring thermo energy to and/or from a laboratory culture plate is provided as well as its methods of use. The temperature transfer device comprises...
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US20090258394 |
METHOD FOR THE PRODUCTION OF HIGH-LEVEL SOLUBLE HUMAN RECOMBINANT INTERFERON ALPHA IN E. COLI AND VECTORS USEFUL FOR SUCH A PRODUCTION
A method for the production of high-level soluble human recombinant interferon alpha protein (rhuIFNα) in E. coli and vectors useful for such a production which comprises: (1) transforming an ...
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US20090258389 |
Construction of New Variants of Dextransucrase DSR-S by Genetic Engineering
The present invention relates to a recombinant process for the production of truncated and/or mutated dextransucrases while conserving their enzymatic activity and/or their specificity in the...
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US20090258357 |
CYTOKINE RECEPTOR COMMON GAMMA CHAIN LIKE
The present invention relates to a novel human gene encoding a polypeptide which is a member of the Cytokine Receptor family. More specifically, the present invention relates to a polynucleotide...
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US20090258051 |
Microbes Encapsulated Within Crosslinkable Polymers
The invention relates to porous films comprising crosslinked electrospun hydrogel fibers. Viable microbes are encapsulated within the crosslinked electrospun hydrogel fibers. The crosslinked...
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US20090253667 |
18 ,21-Didesoxymacbecin Derivatives for the Treatment of Cancer
The present invention relates to 18,21-didesoxymacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous...
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US20090253643 |
EQUOL LEVEL REGULATOR
An object of the invention is to provide a medical drug, a food and drink having a role in regulating the concentration of equal in vivo and being capable of taking for a long time with high safety...
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US20090253167 |
Methanol-responsive promoter, fusion gene comprising promoter and foreign gene connected so that foreign gene can be expressed, vector, transformant, and method of producing protein
A methanol-responsive promoter includes the following regions (1) and (2) in this order in the direction from its 5′- to 3′-terminal (1) a methanol-responsive region that is selected from the...
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US20090246838 |
Process For The Production Of Cadaverine
Process for the production of cadaverine by constructing a recombinant microorganism which has a deregulated lysine decarboxylase gene and at least one deregulated gene selected from the group (i)...
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US20090246836 |
Pgro expression units
The present invention relates to the use of nucleic acid sequences for regulating the transcription and expression of genes, the novel promoters and expression units themselves, methods for...
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US20090246755 |
Method of examining chemical using gene-disrupted strain
A method having higher sensitivity in a bioassay method utilizing cell response of a microorganism, for detecting the presence of a chemical in a test specimen is provided. The method of the...
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US20090242879 |
Optoelectronic device and method of fabricating the same
A modified isolated polypeptide comprising an amino acid sequence encoding a photocatalytic unit of a photosynthetic organism being capable of covalent attachment to a solid surface and having a...
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US20090239816 |
Multitargeting Interfering RNAs And Methods Of Their Use And Design
Interfering RNA molecules are now designed and produced with specificity for multiple binding sequences present in distinct genetic contexts in one or more pre-selected target RNA molecules and are...
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US20090239281 |
Moving A Small Object in A Direction
For directional motion of a small object, a combination of at least two different properties is imparted to the object. At least one of the properties being responsive to an external influence to...
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US20090239272 |
Production of flavonoids by recombinant microorganisms
Methods and compositions are provided for production of flavonoids in microbial hosts. The compositions comprises a set of genes which encode for enzymes involved in one or more steps in the...
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US20090239256 |
Detection of Micro-Organisms
The present invention relates to a method of detecting the presence of a viable micro-organism of interest in a sample containing a contaminating micro-organism.
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US20090239239 |
EUKARYOTIC AMADORIASE HAVING EXCELLENT THERMAL STABILITY, GENE AND RECOMBINANT DNA FOR THE EUKARYOTIC AMADORIASE, AND PROCESS FOR PRODUCTION OF EUKARYOTIC AMADORIASE HAVING EXCELLENT THERMAL STABILITY
Disclosed are: a eukaryotic amadoriase which is prepared by introducing a mutation into DNA encoding a eukaryotic amadoriase derived from a microorganism belonging to the genus Coniochaeta or ...
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US20090238822 |
Chimeric Hepatitis C Virus Antigens For Eliciting an Immune Response
Disclosed herein are chimeric antigens, comprising an hepatitis C virus (HCV) antigen and a Fc fragment of an immunoglobulin for eliciting an immune response against said antigen. The immune...
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US20090238819 |
THERAPEUTIC AND DIAGNOSTIC AGENTS
The present invention relates generally to therapeutic and diagnostic agents. More particularly, the present invention provides molecules having structural features characteristic of...
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US20090233343 |
AFFINITY PURIFICATION OF PROTEIN
We describe fusion proteins comprising a bacterial immunity polypeptide and their use in affinity purification of protein complexes.
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US20090233334 |
CELL CULTIVATION AND PRODUCTION OF RECOMBINANT PROTEINS BY MEANS OF AN ORBITAL SHAKE BIOREACTOR SYSTEM WITH DISPOSABLE BAGS AT THE 1,500 LITER SCALE
The present invention provides a novel method for culturing cells as well as a novel method for producing a recombinant protein by culturing cells at large scale (up to 1,500 L nominal volume and...
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US20090232830 |
Modified HIV-1 Envelope Proteins
The present invention relates to modified HIV-1 envelope proteins which express epitopes that produce a broadly cross reactive neutralizing response, their methods of use and antibodies which bind...
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US20090232817 |
Antigen binding molecules that bind EGFR, vectors encoding same, and uses thereof
The present invention relates to antigen binding molecules (ABMs). In particular embodiments, the present invention relates to recombinant monoclonal antibodies, including chimeric, primatized or...
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