Matches 1 - 50 out of 378 1 2 3 4 5 6 7 8 >


Match Document Document Title
US20140141992 NEOEPITOPE DETECTION OF DISEASE USING PROTEIN ARRAYS  
A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of...
US20110306507 METHOD AND TOOLS FOR PROGNOSIS OF CANCER IN HER2+PARTIENTS  
A gene or protein set includes at least 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, and possibly 40, 45, 50,...
US20140086838 IDENTIFICATION OF A NEW MOLECULAR FACTOR FOR EARLY DIAGNOSIS OF UROTHELIAL CARCINOMA OF THE BLADDER  
The identification is disclosed of a new molecular factor for the early diagnosis of urothelial carcinoma of the bladder. HtrA1 is a molecule that is produced mainly by the urothelium of the...
US20150173383 VARIANTS OF CHYMOSIN WITH IMPROVED MILK-CLOTTING PROPERTIES  
Variants of chymosin with improved milk-clotting properties.
US20140328818 Proteases for Degrading Gluten  
Gluten-degrading proteases derived from insects, including flour beetles, are isolated, and the purified, and recombinant forms can be used to make gluten-containing food safe for patients...
US20130045195 Proteases for Degrading Gluten  
Gluten-degrading proteases derived from insects, including flour beetles, are isolated, and the purified, and recombinant forms can be used to make gluten-containing food safe for patients...
US20120010557 Drug Delivery System for Use in the Treatment of Vascular and Vessel-Related Pathologies  
The present invention relates to a drug delivery system for use in the treatment of vascular and vessel-related pathologies, comprising a drug delivery platform that comprises at least one...
US20120040905 MEANS FOR PURIFYING A COAGULATION PROTEIN, AND METHODS FOR IMPLEMENTING SAME  
An affinity substrate for selectively binding a coagulation protein, includes a substrate solid on which nucleic aptamers binding specifically to the coagulation protein are immobilized.
US20130243855 Modified coagulation factor IX polypeptides and use thereof for treatment  
Provided are modified factor IX (FIX) polypeptides and methods of generating modified FIX polypeptides. Also provided are pharmaceutical compositions, including compositions formulation for oral...
US20110236397 LIMITED PROTEOLYSIS OF CD2AP AND PROGRESSION OF RENAL DISEASE  
Compositions which specifically block cathepsin L function in podocytes, compositions which protect cytoskeletal adaptor protein (CD2AP) for degradation, compositions which modulate expression or...
US20130260439 Method for the Production of Proteins  
The present invention relates to a process for the purification of a protease.
US20120225425 Cathepsin E as a Marker of Colon Cancer  
Elevated levels of cathepsin E (catE) are demonstrated to be diagnostic of intestinal forms of cancer, such as colorectal cancer. Elevated levels of cathepsin E (catE, monomeric forms) are...
US20150064744 MODIFIED ENTEROKINASE LIGHT CHAIN  
The present invention is related to novel mammalian enterokinase analogues such as mammalian enterokinase light chain analogues and methods of making such. Also described herein is a method for...
US20110263499 IFBM'S TO PROMOTE THE SPECIFIC ATTACHMENT OF TARGET ANALYTES TO THE SURFACE OF ORTHOPEDIC IMPLANTS  
The present invention provides an improved coating for surfaces of medical implants. The coating comprises at least one interfacial biomaterial (IFBM) which is comprised of at least one binding...
US20140087443 OVER EXPRESSION OF FOLDASES AND CHAPERONES IMPROVES PROTEIN PRODUCTION  
The present teachings provide methods for increasing protein secretion, e.g., chymosin in filamentous fungi by co-expressing certain chaperone(s) and/or foldase(s). The present teachings also...
US20120122179 MEANS FOR PURIFYING A PROTEIN OF BLOOD PLASMA AND METHODS FOR IMPLEMENTING SAME  
An affinity substrate for the selective binding of a protein of blood plasma includes a solid substrate material on which are immobilized deoxyribonucleic aptamers specifically binding with the...
US20150175940 COMPOSITIONS AND METHODS FOR REDUCING CAT ALLERGENS IN THE ENVIRONMENT  
Formulations, compositions and products for reducing allergenic Fel d 1 from the environment are disclosed. The formulations include at least one protease that interacts with the Fel d 1 and...
US20150023944 Method of Treating and Diagnosing Parkinson's Disease and Related Dysautonomic Disorders  
A method for treating a Parkinson's patient with digestive/pancreatic enzymes involves administering an effective amount of digestive/pancreatic enzymes to an individual having the disorder in...
US20120231505 Gene Expression Technique  
The present invention provides a method for producing a desired protein (such as a desired heterologous protein) comprising: (a) providing a host cell comprising a first recombinant gene encoding...
US20140178357 STABILIZED LIQUID AND LYOPHILIZED ADAMTS13 FORMULATIONS  
The present invention relates to formulations of ADAMTS13 with enhanced or desirable properties. As such, the invention provides liquid and lyophilized formulations of ADAMTS13 that are suitable...
US20120231545 METHOD FOR MODIFYING BOVINE EMBRYO STEM CELLS AND METHOD FOR PURIFYING PROTEINS PRODUCED BY MODIFIED BOVINE EMBRYO STEM CELLS  
The present invention relates to the modification process of bovine embryonic stem cells and purification process of proteins generated by modified stem cells. In particular, the present invention...
US20150210994 FVII Polypeptide Variants Exhibiting Altered Interaction with Endothelial Protein C Receptor (EPCR) and Methods of Use Thereof for Modulating Hemostasis  
Factor VII variants and methods of use thereof are disclosed.
US20140248259 Compositions and Methods for Modulating Hemostasis  
Factor X/Xa variants and methods of use thereof are disclosed.
US20140120155 Compositions and Methods for Modulating Hemostasis  
Factor Xa variants and methods of use thereof are disclosed.
US20110265197 Signatures and PCDeterminants Associated with Prostate Cancer and Methods of Use Thereof  
The present invention provides methods of detecting cancer using biomarkers.
US20150044207 Clotting Factor-Fc Chimeric Proteins to Treat Hemophilia  
The Invention relates to a chimeric protein comprising at least one clotting factor and at least a portion of an immunoglobulin constant region. The invention relates to a method of treating a...
US20120164127 MIRAC PROTEINS  
This disclosure relates to a method of generating conditionally active biologic proteins from wild type proteins, in particular therapeutic proteins, which are reversibly or irreversibly...
US20150246139 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF NUCLEAR PROTEINS  
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
US20150064236 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS  
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
US20140329294 CELL CULTURE MEDIUM FOR ADAMTS PROTEIN EXPRESSION  
The present invention provides culture mediums that are useful for the expression of ADAMTS proteins, such as ADAMTS13. Methods for the expression and purification of ADAMTS proteins are also...
US20130071906 CELL CULTURE MEDIUM FOR ADAMTS PROTEIN EXPRESSION  
The present invention provides culture mediums that are useful for the expression of ADAMTS proteins, such as ADAMTS13. Methods for the expression and purification of ADAMTS proteins are also...
US20150132770 PREGNANCY-ASSOCIATED PLASMA PROTEIN-A2 (PAPP-A2) POLYNUCLEOTIDES  
The present invention provides pregnancy associated plasma protein A2 (PAPP-A2), its nucleotide and amino acid sequences, antisense molecules to the nucleotide sequences which encode PAPP-A2,...
US20140302592 PROTEIN PURIFICATION BY ANION EXCHANGE CHROMATOGRAPHY  
The present invention relates to a two-step method for the purification of divalent cation binding proteins with high yield and high purity on anion exchange resin materials, to divalent cation...
US20140302591 PROTEIN PURIFICATION BY ANION EXCHANGE CHROMATOGRAPHY  
The present invention relates to a two-step method for the purification of divalent cation binding proteins with high yield and high purity on anion exchange resin materials, to divalent cation...
US20110312059 TAU PROTEASE COMPOSITIONS AND METHODS  
Tau protein has a causative role in Alzheimer's disease and multiple other neurodegenerative disorders exhibiting tau histopathology collectively termed tauopathies. The primary function of tau...
US20110126303 Modified Blood Clotting Factors And Methods Of Use  
The invention provides compositions including modified blood clotting factors that have a non-native proteolytic cleavage site engineered into them allowing intracellular cleavage and secretion of...
US20140199287 NON-NEUROTOXIC PLASMINOGEN ACTIVATING FACTORS FOR TREATING OF STROKE  
The invention concerns the use and the production of non-neurotoxic plasminogen activating factors, derived, for example, from the common vampire Desmodus rotundus (DSPA), for therapeutic...
US20130039902 NON-NEUROTOXIC PLASMINOGEN ACTIVATING FACTORS FOR TREATING OF STROKE  
The invention concerns the use and the production of non-neurotoxic plasminogen activating factors, derived, for example, from the common vampire Desmodus rotundus (DSPA), for therapeutic...
US20110206704 Methods and compositions for modulating hepatocyte growth factor activator  
The present invention relates generally to the fields of molecular biology and growth factor regulation. More specifically, the invention concerns modulators of hepatocyte growth factor activator...
US20110294141 METHOD FOR ANALYZING PSA AND METHOD FOR DISTINGUISHING PROSTATE CANCER FROM PROSTATIC HYPERTROPHY USING THAT METHOD FOR ANALYZING PSA  
A method for distinguishing prostate cancer from prostatic hypertrophy using the method for analyzing PSA and an analysis kit of PSA are provided. An object of the present invention can be solved...
US20140044681 Cathepsin K As A Marker For Cartilage Production, Repair and Regeneration  
Ctsk is used as a marker to identify, track, and manipulate Ctsk positive cartilaginous stem cells for cartilage repair and regeneration in vitro and in vivo.
US20130017546 Breast Tumor Markers and Methods of Use Thereof  
Newly identified proteins as markers for the detection of breast tumors, or as therapeutic targets for treatment thereof; affinity ligands capable of selectively interacting with the newly...
US20150104849 METHODS OF PURIFYING RECOMBINANT ADAMTS13 AND OTHER PROTEINS AND COMPOSITIONS THEREOF  
Provided herein are methods for purifying recombinant A Disintegrin-like and Metallopeptidase with Thrombospondin Type 1 Motif 13 (ADAMTS13) protein from a sample. The method comprises enriching...
US20110081700 Methods of Purifying Recombinant Adamts13 and Other Proteins and Compositions Thereof  
Provided herein are methods for purifying recombinant A Disintegrin-like and Metallopeptidase with Thrombospondin Type 1 Motif 13 (ADAMTS13) protein from a sample. The method comprises enriching...
US20140356886 METHOD FOR MEASURING BETA-GLUCAN, AND BETA-GLUCAN-BINDING PROTEIN FOR USE IN THE METHOD  
Disclosed are a method for measuring βG comprising the steps of bringing a sample into contact with a βG-binding protein 1 and a βG-binding protein 2, each comprising an amino acid sequence which...
US20130022983 Colon and Rectal Tumor Markers and Methods of Use Thereof  
Newly identified proteins as markers for the detection of colon and rectal tumors, or as therapeutic targets for treatment thereof; affinity ligands capable of selectively interacting with the...
US20150010556 SERINE PROTEASE MOLECULES AND THERAPIES  
Cell-targeted serine protease constructs are provided. Such constructs can be used in methods for targeted cell killing such as for treatment cell of proliferative diseases (e.g., cancer). In some...
US20130095555 Hyperglycosylated Human Coagulation Factor IX  
The invention relates to hyperglycosylated human coagulation factor IX polypeptides, to processes for preparing said polypeptides, to pharmaceutical compositions comprising said polypeptides and...
US20110162094 MODIFIED HUMAN FACTOR VII/VIIA AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME  
Modified factors VII/VIIa with a high stability, nucleic acids encoding such modified factors VII/VIIa, and methods of preparing the same.
US20140148502 MODIFIED POLYNUCLEOTIDES FOR TREATING PROTEIN DEFICIENCY  
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.

Matches 1 - 50 out of 378 1 2 3 4 5 6 7 8 >