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US20090291427 |
INTEGRATION OF SAMPLE STORAGE AND SAMPLE MANAGEMENT FOR LIFE SCIENCE
Compositions and methods are disclosed for automated storing, tracking, retrieving and analyzing biological samples, including dry storage at ambient temperatures of nucleic acids, proteins...
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US20090286221 |
Device Comprising a Container System for a Bodily Fluid
The invention relates to a device for separating a bodily fluid, in particular blood platelet concentrate, into fractions under centrifugal force. The device comprises a flexible container system...
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US20090280470 |
EXTRACTION AND DIAGNOSTIC FLUID DEVICES, SYSTEMS AND METHODS OF USE
The present invention provides devices, systems and methods for RNA isolation from biological samples containing white blood cells, such as whole blood. The devices have a device body that includes...
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US20090274630 |
RED BLOOD CELL-DERIVED VESICLES AS A NANOPARTICLE DRUG DELIVERY SYSTEM
Red blood cell-derived vesicles (RDV) as a nanoparticle drug delivery system. The RDV are smaller than one micrometer, capable of encapsulating and delivering an exogenous substance into cells. The...
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US20090270509 |
NITRIC OXIDE-RELEASING MOLECULES
This invention relates to compositions comprising carbon-based diazeniumdiolates that release nitric oxide (NO). The carbon-based diazeniumdiolated molecules release NO spontaneously under...
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US20090263781 |
Composition for Preserving Platelets and Method of Using the Same
The present invention relates to compositions and methods for storing platelets to preserve the function and freshness of the platelets. More particularly, the present invention relates to the use...
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US20090258338 |
SIMULATED 5-PART DIFFERENTIAL LEUKOCYTE GRANULES, THE METHOD FOR PREPARING THE SAME AND CONTROL PRODUCTS AND CALIBRATORS COMPRISING THE SAME
A method for preparing five-part differential leukocyte analogs from red blood cells includes selecting appropriate red blood cells; treating the red blood cells with a multi-functional reagent...
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US20090257991 |
Engineering and Delivery of Therapeutic Compositions of Freshly Isolated Cells
The present invention relates to the transient modification of cells. In particular embodiments, the cells are immune systems, such as PBMC, PBL, T (CD3+ and/or CD8+) and Natural Killer (NK) cells....
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US20090253115 |
COMPOSITION FOR PRESERVING PLATELETS AND METHOD OF USING THE SAME
The present invention relates to compositions and methods for storing platelets to preserve the function and freshness of the platelets. More particularly, the present invention relates to the use...
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US20090246750 |
Devices and Methods for Collection, Storage and Transportation of Biological Specimens
The present invention provides methods for collecting, storing or transporting liquid suspension of biological specimens containing analytes of interest in a dry state. The dried biological...
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US20090239208 |
Red Blood Cell Storage Medium For Extended Storage
Synthetic aqueous storage solutions are disclosed for use in the processing and the storing of red blood cells prepared from whole blood including cells derived from whole blood held for an...
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US20090226880 |
Method for staining cells for identification and sorting
The present invention provides novel methods of cell staining, such as bovine sperm, using electroporation or osmolality treatments at viability-enhancing temperatures. Furthermore, methods of...
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US20090226879 |
Protein-Free Gamete and Embryo Handling and Culture Media Products
This invention discloses a substantially protein-free cell culture solution for assisted reproductive technologies and methods of use thereof.
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US20090220933 |
DETECTION OF FETAL CELLS FROM MATERNAL BLOOD
The present application relates to methods for identification of foetal cells and generation and isolation of binding members recognising foetal cells. Said methods may further be used for other...
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US20090220932 |
DEVICE AND METHOD FOR COMBINED MICROFLUIDIC-MICROMAGNETIC SEPARATION OF MATERIAL IN CONTINUOUS FLOW
A miniaturized, integrated, microfluidic device pulls materials bound to magnetic particles from one laminar flow path to another by applying a local magnetic field gradient. The device removes...
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US20090220931 |
FUNCTIONAL IN VITRO IMMUNOASSAY
The invention relates to a method for the in vitro investigation of the effect of substances in in vivo processes and an in vitro detection method for the identification of immunomodulating...
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US20090220930 |
Time Varying Electromagnetic Force Sleeve for the Expansion of Cells and Method of Using the Same
A time varying electromagnetic force sleeve wherein the time varying electromagnetic force sleeve comprises a time varying electromagnetic force source operatively connected to an electrically...
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US20090220585 |
Biological Active Blood Serum Fraction S-1-10, Methods for Producing It and Uses Thereof
The present invention relates to a method for preparing a biological active fraction of blood serum, the biological active fraction (S-1-10) and a pharmaceutical composition comprising said...
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US20090220474 |
NOVEL A-GALACTOSIDASES
This invention relates to novel α-galactosidases for the enzymatic removal of the immunodominant monosaccharides on blood products and tissues. Specifically this invention provides a novel family...
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US20090220466 |
VERY SMALL EMBRYONIC-LIKE (VSEL) STEM CELLS AND METHODS OF ISOLATING AND USING THE SAME
The presently disclosed subject matter provides populations of stem cells that are purified from bone marrow, peripheral blood, and/or other sources. Also provided are methods of using the stem...
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US20090214626 |
Platinum Complexes For Targeted Drug Delivery
The subject invention concerns biotin-conjugated platinum complexes that exhibit direct and indirect (immunological) antitumor cell activity. The subject invention also concerns the biotin-platinum...
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US20090208920 |
ASSAY DEVICE AND METHOD
There is provided an assay device comprising a lid and a base, said base comprising, a sample addition zone, a reaction zone and an absorbing zone, said components being in fluid connection and...
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US20090208919 |
PARTICLE MATRIX FOR STORAGE OF BIOMOLECULES
Matrices for manipulation of biopolymers, including the separation, purification, immobilization and archival storage of biopolymers is disclosed.
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US20090208517 |
Preparation Of Antigen-Presenting Human Gamma-Delta T Cells And Use In Immunotherapy
The invention relates to a method for the preparation of efficient antigen-presenting human γδ T cells, to the γδ T cells prepared by such a method, and to their use in immunotherapy,...
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US20090202982 |
BLOOD-VISCOSITY REDUCING AGENT
A blood-viscosity reducing agent contains a protein derived from Bacillus subtilis natto and including, sequentially from an amino group terminal, a first structural amino acid sequence having...
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US20090202981 |
Triple spin, double pool and revolumization process for concentrating platelets and derivative platelet concentrate
The present invention comprises an improved method of manufacturing platelet concentrate comprising the steps of: performing a first centrifugation of anticoagulated blood, pooling a first platelet...
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US20090202980 |
Cross-Beta Structure Comprising Amyloid Binding Proteins and Methods for Detection of the Cross-Beta Structure, for Modulating Cross-Beta Structures Fibril Formation and for Modulating Cross-Beta Structure-Mediated Toxicity and Method for Interfering With Blood Coagulation
The invention relates to the field of biochemistry, molecular biology, structural biology and medicine. More in particular, the invention relates to cross-β structures and the biological role of...
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US20090202979 |
Production of antibody formats and immunological applications of said formats
The invention concerns an in-vitro method for introducing a targeted genome modification into an oocyte or an egg and a method for performing a random insertion in the genome of a host cell.
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US20090196938 |
USE OF A MATRIX FOR REMOVING C-REACTIVE PROTEIN FROM BIOLOGICAL FLUIDS
The present invention relates to a method for treating the risk of increased C-reactive protein (CRP) levels by conducting extracorporeal perfusion of blood plasma from patients with risk for...
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US20090191537 |
MEDIUM AND METHODS FOR THE STORAGE OF PLATELETS
Synthetic storage media are disclosed for use in the processing and the storing of platelets. The storage media includes a platelet storage solution and less than 20 percent plasma to preserve...
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US20090191535 |
Method of assessing metastatic carcinomas from circulating endothelial cells and disseminated tumor cells
A method for assessing cancer in test subjects is described based upon enumeration of circulating endothelial cells and/or disseminated tumor cells in a test subject. This method is used to...
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US20090186335 |
METHOD OF PREPARING UNILAMELLAR VESICLES FOR THE CRYOPRESERVATION AND CULTURE OF GERM CELLS AND EMBRYOS
In order to prepare the unilamellar low-density lipid vesicles, a presolution of vegetable lipids is first prepared; a suitable quantity of lipids, between 4 and 12 mg/ml, mixed with pure water,...
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US20090186334 |
Non-Embryonic Totipotent Blastomere-Like Stem Cells And Methods Therefor
Human non-embryonic adult totipotent and pluripotent stem cells are isolated in a simplified serum-free and feeder cell-free process. Most remarkably, certain stem cells, and especially BLSCs, are...
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US20090162830 |
REAGENTS AND METHODS FOR CLASSIFYING LEUKOCYTES
A reagent for classification of leukocytes includes (a) at least two cationic surfactants; (b) at least one organic compound bearing a hydrophobic group and an anionic group; (c) a buffer for...
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US20090155838 |
Devices, systems and methods for the collection, stimulation, stabilization, and analysis of a biological sample
Devices, systems, methods and kits for the collection, stimulation, stabilization and analysis of biological samples, including blood samples, are disclosed. An embodiment of the invention includes...
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US20090155764 |
WHITE BLOOD CELL DIFFERENTIATION REAGENT AND METHOD
A reagent for four-part differentiation of white blood cells is provided. In one embodiment the reagent has an osmolarity below 50 mOsm/kg H 2 O. A method for differentiating white blood cells...
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US20090155763 |
COMPOSITIONS AND METHODS FOR PROLONGING SURVIVAL OF PLATELETS
The present invention provides modified platelets having a reduced platelet clearance and methods for reducing platelet clearance. Also provided are compositions for the preservation of platelets....
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US20090155762 |
Device and Method for Separating and Discharging Plasma
The invention concerns plasma separation on a microliter scale. The method/system according to the invention is able to provide plasma in the range of several microliters within a very short time...
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US20090155761 |
Method for Producing Reticulocyte Lysate and Uses Thereof
Methods for producing substantially pure porcine reticulocyte lysate are provided. In one embodiment, the methods include inducing a reduction in the hematocrit of a pig to a level of between about...
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US20090142744 |
Method for the Analysis of a Blood Sample, and Apparatus and Reagent for Its Implementation
Method for the automatic analysis of a blood sample in which: an analysis solution containing the blood sample, a diluent, and at least one compound to lyze the erythrocytes; at least one compound...
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US20090142371 |
HIV RECOMBINANT VACCINE
Reagents and methods for making and using HIV recombinant vaccines are disclosed.
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US20090136586 |
Method for Extracorporeal Removal of a Pathogenic Microbe, an Inflammatory Cell or an Inflammatory Protein From Blood
The present invention relates to a method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from mammalian blood/use of a device comprising a...
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US20090130647 |
METHOD AND APPARATUS FOR SORTING PARTICLES
A method and an apparatus using acridine orange for sorting particles to precisely carry out the measurement of cells in the blood are provided. The cells in the blood is sorted by the steps of...
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US20090130646 |
BLOOD COLLECTION DEVICE, METHOD, AND SYSTEM FOR USING THE SAME
Disclosed is a fluid collection device wherein multiple, individual samples of fluid can be collected simultaneously. The device includes a chamber and an adapter which substantially and...
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US20090130645 |
METHOD FOR ASSESSING THE FIBRINOGEN CONTRIBUTION IN COAGULATION
The present invention is directed to a diagnostic method for the determination of a coagulopathy in a patient, in particular, for calculating the individual need of blood components, preferably...
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US20090130124 |
Method for altering hematopoietic progenitor cell adhesion, differentiation, and migration
The present invention satisfies the need in the art by providing methods for altering hematopoietic progenitor cell adhesion and/or migration to a target tissue, and for altering hematopoietic...
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US20090123907 |
LYSINE CITRATE FOR PLASMA PROTEIN AND DONOR PROTECTION
An improved anticoagulant or additive is based on a higher level of citric acid than is usual (at least about 1.0% weight by volume). The higher citrate is combined with an amino acid as a...
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US20090123906 |
Reproductive cell system
Compositions or extracts ( 2 )( 15 )( 24 )( 25 )( 16 )( 23 )( 31 )( 36 )( 41 ) obtained from the fruit ( 4 ) or leaves ( 26 ) of plants of the genus Hippophea ( 1 ) and methods of using such...
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US20090117532 |
Pre-clinical method for monitoring serial changes in circulating breast cancer cells in mice
The CellTracks® System provides a system to enumerate CTC's in blood. The system immunomagnetically concentrates epithelial cells, fluorescently labels the cells and identifies and quantifies...
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US20090111087 |
Separation method of Nucleated Cells Derived from Bone Marrow for Bone Formation
The present invention relates to a method for separating bone marrow-derived nucleated cells for bone formation. The method comprises: the steps of: washing bone marrow; lysing red blood cells in...
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