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US20130137595 BIOMARKERS FOR LYMPHOMA  
A biomarker, method, test kit, and diagnostic system for detecting the presence of lymphoma in a person are disclosed. The lymphoma may be Hodgkin's lymphoma or non-Hodgkin's lymphoma. The person...
US20150005183 PROTEIN BIOMARKERS OF LATE STAGE BREAST CANCER  
This patent application discloses and describes proteins found to be differentially expressed between primary tumor breast cancer cells histologicaly defined as early stage (stage 0) breast cancer...
US20130183737 NOVEL BIOMARKERS OF LIVER CANCER  
The invention is based on the surprising finding that proteins regulated by excessive EGFR signalling in the liver may be used as biomarkers in the diagnosis, prognosis and/or monitoring of...
US20140051134 METHOD FOR PRODUCING PHOSPHITE DEHYDROGENASE PROTEIN AND USE THEREOF  
In order to provide: a phosphite dehydrogenase protein having both improved solubility and improved heat stability; a method for producing a gene encoding the phosphite dehydrogenase protein; a...
US20140193869 CELL-FREE SYSTEM FOR CONVERTING METHANE INTO FUEL AND CHEMICAL COMPOUNDS  
The present disclosure relates, in some aspects, to cell-free methods and systems for large-scale conversion of methane to isobutanol, comprising combining, in a bioreactor at elevated pressure,...
US20130095551 METHOD FOR CHANGING CONFORMATION OF GLOBULAR PROTEINS  
A method for changing conformation of globular proteins is provided. The method controls the concentration of the globular proteins and the adsorption time of the globular proteins from the...
US20110085939 NODE POLYPEPTIDES FOR NANOSTRUCTURE ASSEMBLY  
Engineered proteins are used in the assembly of two-dimensional and three-dimensional nanostructure assemblies, based on systematic design and production of protein node structures that can be...
US20110189686 SCREENING FOR MODULATORS OF CYP2B15 AND/OR GPD1 FOR THE TREATMENT OF ACNE, OF SEBORRHOEIC DERMATITIS OR OF HYPERSEBORRHOEA  
An in vitro or in vivo method for screening for candidate compounds for the preventive or curative treatment of acne, of seborrhoeic dermatitis or of skin disorders associated with...
US20120231505 Gene Expression Technique  
The present invention provides a method for producing a desired protein (such as a desired heterologous protein) comprising: (a) providing a host cell comprising a first recombinant gene encoding...
US20110318809 METHOD OF SCREENING PLACENTAL PROTEINS RESPONSIBLE FOR PATHOPHYSIOLOGY OF PREECLAMPSIA, AND MARKER FOR EARLY DIAGNOSIS AND PREDICTION OF PREECLAMPSIA  
The present invention relates to a method of screening placental proteins responsible for pathophysiology of preeclampsia, and a marker for early diagnosis and prediction of preeclampsia. In...
US20110052638 ALLERGENS FROM ASPERGILLUS VERSICOLOR, AND METHOD OF DETECTING A MOLD ALLERGY CAUSED BY INTERIOR ROOMS  
The invention relates to seven allergens of Aspergillus versicolor which are suitable for specific diagnostics of this mold which predominantly pollutes the interior. The invention is also...
US20110195478 BLADDER CANCER BIOMARKER AND TEST METHOD USING THE SAME  
The present invention discloses a bladder cancer biomarker and a test method using the same. The biomarker contains at least one of the mentioned 69 compounds, such as apolipoprotein A1 (APOA1),...
US20140295457 GENE CLUSTER FOR BIOSYNTHESIS OF GRISELIMYCIN AND METHYLGRISELIMYCIN  
The present invention refers to the gene cluster and genes comprised by the gene cluster which are involved in the biosynthesis of griselimycin and methylgriselimycin and to the use of the gene...
US20140030749 MODIFIED GLUCOSE DEHYDROGENASE  
The present invention relates to glucose dehydrogenase [NAD(P)+GDH] using nicotinamide adenine dinucleotide or nicotinamide adenine dinucleotide phosphate as a coenzyme, in which the thermal...
US20150125925 COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS  
The present invention provides consumer products comprising a serine protease variant, more specifically subtilisin variants produced there from. Specifically, the present invention provides...
US20130240374 Glucose Dehydrogenase/Cytochrome Fusion Protein  
A fusion protein of pyrroloquinoline quinone glucose dehydrogenase (PQQGDH) and a cytochrome is disclosed. PQQGDH is, for example, a water-soluble PQQGDH derived from Acinetobacter calcoaceticus....
US20130210037 METHODS OF DIAGNOSING AND TREATING AUTISM  
The present invention provides diagnostic methods for determining the risk of developing an autism spectrum disorder (ASD) in a fetus or child by detecting in a biological sample from the mother...
US20120231503 Gene Expression Technique  
The present disclosure relates to a method for producing heterologous protein including: (c) providing a host cell comprising a 2 μm-family plasmid, the plasmid comprising a gene encoding a...
US20150031109 POLYOL OXIDASES  
The present invention provides compositions and methods for producing a polyol oxidase in micoroorganisms, and the use of polyol oxidases in cleaning compositions. The invention includes cleaning...
US20130196891 Polyol Oxidases  
The present invention provides compositions and methods for producing a polyol oxidase in micoroorganisms, and the use of polyol oxidases in cleaning compositions. The invention includes cleaning...
US20110154581 POLYOL OXIDASES  
The present invention provides compositions and methods for producing a polyol oxidase in micoroorganisms, and the use of polyol oxidases in cleaning compositions. The invention includes cleaning...
US20140178933 ENHANCED HETEROLOGOUS PROTEIN PRODUCTION IN KLUYVEROMYCES MARXIANUS  
An expression vector which is capable of overexpressing a protein of interest in a host cell, a host cell comprising the expression vector, and a method of producing a protein of interest are...
US20140017748 MODIFIED ALCOHOL DEHYDROGENASES FOR THE PRODUCTION OF FUELS AND CHEMICALS  
The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In...
US20110201072 Modified alcohol dehydrogenases for the production of fuels and chemicals  
The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In...
US20140212942 PRODUCTION OF VOLATILE DIENES BY ENZYMATIC DEHYDRATION OF LIGHT ALKENOLS  
Described is a method for generating conjugated dienes through a biological process. More specifically, the application describes a method for producing conjugated dienes (for example butadiene,...
US20120021468 PRODUCTION OF L-RIBOSE AND OTHER RARE SUGARS  
The invention provides methods and compositions for the production of L-ribitol and other rare sugars using a mannitol-1-dehydrogenase or a polyol-1-dehydrogenase.
US20150203568 ALBUMIN FUSION PROTEINS  
The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors...
US20110189755 METHOD FOR THE PRODUCTION OF AN ADDITIVE FOR THE ENZYMATIC DECOMPOSITION OF MYCOTOXINS, ADDITIVE, AND USE THEREOF  
In a method for producing an additive for the enzymatic degradation of mycotoxins, in particular fumonisins, it is provided that at least one nucleic acid sequence of genes corresponding to...
US20110236935 OXIDATION PROCESS  
A method of oxidising a saccharide, by contacting the saccharide with an alcohol dehydrogenase (ADH) enzyme selected from a quinone redox cofactor-dependent ADH, a nicotinamide adenine...
US20130052679 L-THREONINE ANALYSIS METHOD AND L-THREONINE DEHYDROGENASE  
A method for analyzing L-threonine contained in an specimen, which includes the steps of mixing a sample containing the specimen with an L-threonine dehydrogenase derived from Cupriavidus necator...
US20150191705 AgsE-DEFICIENT STRAIN  
The present invention relates to a mutant microbial host cell which is deficient in the production of the AgsE protein or in the production of an homologous thereof if compared with a parent...
US20110294697 SYSTEM FOR DETECTNG PROTEASE  
Disclosed is a system for detecting a protease inside a cell. In one embodiment, the system includes a chimeric protein that comprises as covalently linked components: 1) at least one optionally...
US20150232894 LACTATE DEHYDROGENASE MUTANT, POLYNUCLEOTIDE CODING FOR THE MUTANT, YEAST CELL INCLUDING THE POLYNUCLEOTIDE, METHOD OF PREPARING THE MUTANT, AND METHOD OF PRODUCING THE LACTATE USING THE SAME  
A lactate dehydrogenase mutant, a polynucleotide encoding the mutant, a recombinant yeast cell including the polynucleotide, and a method of preparing the mutant and a method of producing lactate...
US20120028911 Mucin Derived Polypeptides  
The present technology relates to isolated MUC17, Muc3 or MUC3 derived polypeptides and polynucleotides encoding the same. The MUC17, Muc3 or MUC3 derived polypeptides and polynucleotides can be...
US20110185450 PLANT 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE  
This invention relates to an isolated nucleic acid fragment encoding a 1-deoxy-D-xylulose 5-phosphate reductoisomerase. The invention also relates to the construction of a chimeric gene encoding...
US20140377799 METHOD FOR SECRETORY PRODUCTION OF GLYCOPROTEIN HAVING HUMAN-TYPE SUGAR CHAIN USING PLANT CELL  
A method for the secretory production of a glycoprotein having a human-type sugar chain, comprising a step of introducing a gene of an enzyme capable of performing a transfer reaction of a...
US20130164782 METHOD FOR SECRETORY PRODUCTION OF GLYCOPROTEIN HAVING HUMAN-TYPE SUGAR CHAIN USING PLANT CELL  
A method for the secretory production of a glycoprotein having a human-type sugar chain, comprising a step of introducing a gene of an enzyme capable of performing a transfer reaction of a...
US20110305688 NEW VIRULENCE FACTORS OF STREPTOCOCCUS PNEUMONIAE  
The present invention provides proteins/genes, which are essential for survival, and consequently, for virulence of Streptococcus pneumoniae in vivo, and thus are ideal vaccine candidates for a...
US20150247152 MUTANT CELLS FOR PROTEIN SECRETION AND LIGNOCELLULOSE DEGRADATION  
The present disclosure provides mutant cells for the secretion of proteins and for the degradation of lignocellulosic biomass. Methods for the use of these cells are also provided. Specifically,...
US20140045243 MUTANT CELLS FOR PROTEIN SECRETION AND LIGNOCELLULOSE DEGRADATION  
The present disclosure provides mutant cells for the secretion of proteins and for the degradation of lignocellulosic biomass. Methods for the use of these cells are also provided. Specifically,...
US20140259223 METHODS FOR PRODUCING CINNAMOLIDE AND/OR DRIMENDIOL  
Described is a nucleic acid sequence isolated from Persicaria hydropiper and encoding a drimenol oxidase protein, expression vectors comprising such nucleic acid sequence, chimeric genes...
US20120164696 RECOMBINANT BETA-GLUCOSIDASE VARIANTS FOR PRODUCTION OF SOLUBLE SUGARS FROM CELLULOSIC BIOMASS  
The invention relates to recombinant expression of a variant form of a fungal C1 strain β-glucosidase. The invention also relates to the generation of fermentable sugars from biomass and the...
US20140356389 PROTEINS AND NUCLEIC ACIDS FROM MENINGITIS/SEPSIS-ASSOCIATED ESCHERICHIA COLI  
Disclosed herein are various open reading frames from a strain of E. coli responsible for neonatal meningitis (MNEC), and a subset of these that is of particular interest for preparing...
US20120309072 METHOD FOR PURIFYING PROTEIN AND GLUCOSE DEHYDROGENASE  
The present invention relates to a method for purifying target protein which contains electron transfer protein, from a protein solution containing the target protein, by means of liquid...
US20150232813 SACCHARIDE OXIDASE, AND PRODUCTION METHOD FOR SAME AND USE OF SAME  
A protein having a novel saccharide oxidase activity capable of being subjected to various uses is provided. The present invention provides a protein having the following physicochemical...
US20150064733 GLYCOSYLATED MODIFIED FLAVIN ADENINE DINUCLEOTIDE-DEPENDENT GLUCOSE DEHYDROGENASES, COMPOSITIONS THEREOF AS WELL AS METHODS OF MAKING AND USING THE SAME  
Compositions, devices, kits and methods are disclosed for assaying glucose with a glycosylated, modified flavin adenine dinucleotide-dependent glucose dehydrogenase (FAD-GDH), variant thereof or...
US20110212458 Methods for Production of Xylitol in Microorganisms  
The invention provides biosynthetic routes to xylitol production that do not require pure D-xylose for synthesis and that can utilize inexpensive substrates such as hemicellulose hydrolysates.
US20150141714 ENGINEERING PLANTS WITH RATE LIMITING FARNESENE METABOLIC GENES  
The disclosed invention provides methods and compositions for increasing terpenoid production, such as sesquiterpenoids, such as farnesene, in plant cells.
US20140308716 NOVEL METHOD FOR PREPARING METABOLITES OF ATORVASTATIN USING BACTERIAL CYTOCHROME P450 AND COMPOSITION THEREFOR  
Provided is a novel method for preparing metabolites of atorvastatin using bacterial cytochrome P450, and a composition therefor, and more particularly, a composition for preparing 2-hydroxylated...
US20140212927 COMPOSITIONS COMPRISING CELLOBIOSE DEHYDROGENASE FROM PYCNOPORUS CINNABARINUS AND THEIR USE FOR THE DEGRADATION OF LIGNOCELLULOSIC BIOMASS  
Enzyme compositions including at least a) a cocktail of cellulases from Trichoderma reesei, and b) an enzymatic cocktail from Pycnoporus cinnabarinus including a cellobiose dehydrogenase (CDH) or...

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