Matches 1 - 50 out of 92 1 2 >


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US20110033896 METHOD FOR MANUFACTURING AN AQUEOUS GLUCOSE SOLUTION FROM PLANTS OF THE TRITICEAE SPECIES  
The present invention relates to a method for manufacturing an aqueous glucose solution from the starch components of Triticeae grains, for example from rye, triticale or in particular wheat...
US20130123563 SELF-DECONTAMINATING METAL ORGANIC FRAMEWORKS  
A self-decontaminating metal organic framework including an acid linked to a metal producing a metal organic framework configured for the sorption of chemical warfare agents and/or toxic...
US20150118719 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS  
The present disclosure provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells...
US20130196013 CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS  
Compositions and methods for controlling molluscs, members of the Gastropoda and Bivalvia classes which includes but is not limited to lactones, lactams, carbamates, amides, and/or carboxylic acid...
US20130121978 CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS  
Compositions and methods for controlling molluscs, members of the Gastropoda and Bivalvia classes which includes but is not limited to lactones, lactams, carbamates, amides, and/or carboxylic acid...
US20140273109 BENZYLISOQUINOLINE ALKALOIDS (BIA) PRODUCING MICROBES, AND METHODS OF MAKING AND USING THE SAME  
Aspects of the invention include host cells that are engineered to produce benzylisoquinoline alkaloids (BIAs). The host cells include heterologous coding sequences for a variety of enzymes...
US20150037850 RECOMBINANT MICROORGANISM PRODUCING QUINOLINIC ACID AND A METHOD FOR PRODUCING QUINOLINIC ACID USING THE SAME  
The present invention relates to a quinolinic acid-producing recombinant microorganism expressing a fusion protein of L-aspartate oxidase and quinolinate synthase linked via a linker, and a method...
US20130189731 MODIFIED TRANSKETOLASE AND USE THEREOF  
The present invention relates to a improved process for the biotechnological production of compounds for which ribose-5-phosphate, ribulose-5-phosphate or xylulose-5-phosphate is biosynthetic...
US20090061491 Novel fermentation method  
This invention relates to a process for recycling biomass in fermentation processes, whereby the biomass that accumulates in the production of fermentation products is prepared by means of a...
US20150259715 L-Lysine Hydroxylase and Production Method for Hydroxy-L-Lysine and Hydroxy-L-Pipecolic Acid Using Same  
The present invention aims to provide a method for efficiently producing hydroxy-L-lysine. The present invention provides a method for producing hydroxy-L-lysine, the method comprising allowing...
US20140322767 DROPLET MICROREACTOR  
The present invention relates to a droplet microreactor, i.e. a microreactor consisting of a droplet of a specific liquid, the microreactor being wall-less, wherein the interface of the specific...
US20140315263 METHOD FOR THE PREPARATION OF NICOTINIC ACID  
A method for the preparation of nicotinic acid, which includes the step of obtaining a culture solution containing quinolinic acid by incubating a microorganism having an ability to produce...
US20130303723 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID  
The invention provides a non-naturally occurring microbial organism having a 6-aminocaproic acid, caprolactam, hexametheylenediamine or levulinic acid pathway. The microbial organism contains at...
US20100330009 COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS  
The present invention relates to derivatives of the 1H-pyrano[4,3-b]benzofuran-1-one structure and their nitrogen analogues which possess powerful antioxidant properties combined with a highly...
US20130302859 Engineered imine reductases and methods for the reductive animation of ketone and amine compounds.  
The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered...
US20150211035 BIOLOGICAL METHOD FOR PRODUCING CIS-5-HYDROXY-L-PIPECOLIC ACID  
A method for producing cis-5-hydroxy-L-pipecolic acid is described. A gene recombinant microorganism enabling direct production of cis-5-hydroxy-L-pipecolic acid can be used in the method. Also...
US20140256003 R-PRAZIQUANTEL PREPARATION METHOD  
Provided are R-praziquantel preparation methods, which utilize the characteristics of biological enzyme of strong stereoselectivity, site-selectivity, and regioselectivity, of high resolution...
US20110045550 Fission Yeast Expressing Cytochrome P450 Reductase  
The present invention refers to a recombinant fission yeast strain useful for the improved production of human cytochrome P450s. The improvement in the cytochrome P450 rate is achieved by a...
US20090162892 Fermentative production of fine chemicals  
The invention relates to a process for the production of at least one microbial metabolite having at least 3 carbon atoms or at least 2 carbon atoms and at least 1 nitrogen atom by means of...
US20150148545 PROTEIN TYROSINE PHOSPHATASE INHIBITOR, PREPARATION METHOD AND USES THEREOF  
Disclosed in the present invention is a protein tyrosine phosphatase inhibitor. The preparation method therefor is: extracting the crude product from the Isaria Fumosorosea Wize solid or liquid...
US20120184000 KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (S,E)-METHYL 2-(3-(3-(2-(7-CHLOROQUINOLIN-2-YL)VINYL)PHENYL)-3-HYDROXYPROPYL)BENZOATE  
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides...
US20140013465 PAPAVER BRACTEATUM WITH MODIFIED ALKALOID CONTENT  
The present invention relates to genetically modified plants of the species Papaver bracteatum wherein the type or amount of one or more alkaloids produced by the plants has been modified....
US20100081571 Novel Euglenoid Derived Alkaloid  
Disclosed herein is a novel purified toxin isolated from Euglena sanguinea. More specifically the toxin, termed euglenophycin, is an alkaloid having herbicidal and cytotoxicity against plant and...
US20140011244 Method for Producing Probiotically Derived Compounds  
A method for producing naturally derived beneficial compounds including dispersing a microbiological culture media including at least one live probiotic organism, and at least one nutraceutical...
US20150031093 L-ASPARTATE OXIDASE VARIANT AND A METHOD FOR PRODUCING QUINOLINATE OR NICOTINIC ACID USING THE SAME  
To produce quinolinate effectively, a L-aspartate oxidase variant that the feedback regulation by nicotinic acid or NAD is released, and a microorganism including the L-aspartate oxidase variant...
US20110195465 Compositions and Methods for Producing Stereoisomerically Pure Statins and Synthetic Intermediates Therefor  
The present disclosure provides ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the...
US20110165186 NOVEL PYRIDINE ALKALOIDS, PREPARATION PROCESS THEREOF, AND THE USES OF THE PYRIDINE ALKALOIDS  
The present invention relates to novel pyridine alkaloid compounds of formula (I): or a pharmaceutically acceptable derivative thereof as described in the specification, the process for the...
US20100184166 METHOD FOR PRODUCING ALKALOIDS  
The present invention provides a method for producing an alkaloid, for example, reticuline, comprising providing dopamine as a substrate for a series of actions of monoamine oxidase,...
US20140342412 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF SUBSTITUTED LACTAMS  
The present disclosure relates to transaminase polypeptides capable of aminating a dicarbonyl substrate, and polynucleotides, vectors, host cells, and methods of making and using the transaminase...
US20120190085 Transaminase Reactions  
The present disclosure relates to methods of using transaminase polypeptides in the synthesis of chiral amines from prochiral ketones.
US20130260426 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF ARMODAFINIL  
The present invention relates to non-naturally occurring polypeptides useful for preparing armodafinil, polynucleotides encoding the polypeptides, and methods of using the polypeptides. The...
US20150211036 GENES AND PROCESSES FOR THE PRODUCTION OF CLAVINE-TYPE ALKALOIDS  
Microorganisms and processes for the recombinant manufacture of clavine-type alkaloids such as cycloclavine, festuclavine, agroclavine, chanoclavine and chanoclavine aldehyde, as well as...
US20060127992 Microorganism and process for preparing vitamin b6  
Disclosed is a recombinant microorganism of the genus Sinorhizobium which is transformed with a vector containing pyridoxol 5′-phophate synthase gene and D-erythrose 4-phosphate dehydrogenase...
US20130115662 FUNGAL PEROXYGENASES AND METHODS OF APPLICATION  
The invention relates to polypeptides having peroxygenase activity and compositions comprising such polypeptides, their encoding polynucleotides, expression vectors and recombinant host cells...
US20120108494 INHIBITORS OF INTRACELLULAR UROKINASE PLASMINOGEN ACTIVATOR AND METHODS OF USE THEREOF  
The present invention provides compositions comprising amiloride amino acid and peptide conjugates. Efficient methods are also provided for administering the compositions for treating cancer and...
US20080269231 Phenazine Compounds and Use Thereof in Autoimmune and Inflammatory Disease  
The invention discloses compounds, compositions and methods useful for preventing and/or treating autoimmune diseases and inflammatory diseases. The methods and compositions utilize water-soluble...
US20110207183 Production Process for Fine Chemicals Using Microorganisms with Reduced Isocitrate Dehydrogenase Activity  
The present invention is directed to a method utilizing a microorganism with reduced isocitrate dehydrogenase activity for the production of fine chemicals. Said fine chemicals may be amino acids,...
US20090312354 DHA Esters and Use Thereof In Treatment and Prevention of Cardiovascular Disease  
The present invention relates to a docosahexaenoic acid ester with an alcohol chosen among the group-B vitamins or provitamins, advantageously comprised by: nicotinyl alcohol of the following...
US20090163443 NOVEL COMPOUND, USEFUL FOR PANCREATIC LIPASE INHIBITION AND THE PROCESS FOR ISOLATION THEREOF  
The present invention relates to a novel, Nonadeca-6-enoic acid-3-(hexadecyloxy-hydroxy-thiophosphoryloxy)-quinoxalin-2 -yl ester designated as streptolipin, useful for pancreatic lipase...
US20080280334 Method for Preparing 3-Hydroxy-4-Hydroxymethyl-Pyrrolidine Compounds  
A process is disclosed for preparing (3R,4R)-3-hydroxy-4-hydroxymethylpyrrolidine, the compound of formula (I), or (3S,4S)-3-hydroxy-4-hydroxymethylpyrrolidine, the compound of formula (Ia)...
US20100036126 STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE  
This invention provides for a compound according to Formula (1), wherein R1 is methyl, ethyl, n-propyl, isopropyl, benzyl or 2-haloethyl and the use thereof in a method to prepare...
US20140004575 MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME  
Provided is a method for efficiently producing from a ketone compound an optically active amino compound useful as an intermediate of a drug, an agricultural chemical, or the like. Provided are: a...
US20080248537 BIOCATALYTIC ASYMMETRIC REDUCTION IN PREPARATION OF (S)-N-[5-(1,2-DIHYDROXY-ETHYL)-PYRAZINYL]-2,2-DIMETHYL-PROPIONAMIDE  
The present invention relates to biocatalytic asymmetric reduction for the preparation of 2-amino-[5-(1-hydroxy-2-hydroxy or halogen-ethyl)]-pyrazine derivatives of the formula wherein R is lower...
US20130337485 ENZYMATIC SYNTHESIS OF ACTIVE PHARMACEUTICAL INGREDIENT AND INTERMEDIATES THEREOF  
The present invention discloses a process for preparing an active pharmaceutical ingredient (API) or intermediates thereof, notably particular step in the synthesis of an intermediate useful for...
US20140256004 Process for the Preparation of an Endothelin Receptor Antagonist  
The present invention relates to a novel process for the preparation of a compound of formula (I) wherein R is a methyl or methoxy group; to certain novel intermediates prepared in such a process...
US20070166809 Processes for the preparations of optically active cyclopentenones and cyclopentenones prepared therefrom  
The present invention relates to novel processes for preparing optically active Cyclopentenones of Formula (R)-1, which are useful for the preparation of Prostaglandins and analogs thereof. The...
US20110229941 Novel Gene Cluster  
Novel isolated DNA sequences which comprise all or part of a gene cluster encoding sanglifehrin synthase, processing and regulatory genes involved in the biosynthesis of a mixed non-ribosomal...
US20100173356 INCREASED PRODUCTION OF A TARGET PRODUCT VIA STABILIZATION OF mRNA  
The present invention relates to newly identified mRNA stabilizing elements useful for the production of a target fermentation product, such as e.g. vitamins or enzymes, in particular riboflavin...
US20090325224 PROCESS FOR PREPARATION OF OPTICALLY ACTIVE N-PROTECTED 3-AMINOPYRROLIDINE OR OPTICALLY ACTIVE N-PROTECTED 3-AMINOPIPERIDINE AND THE CORRESPONDING KETONES BY OPTICAL RESOLUTION OF THE RACEMIC AMINE MIXTURES EMPLOYING A BACTERIAL OMEGA-TRANSAMINASE  
The present invention relates to the production of optically active amines, which can be used as intermediate products in a synthesis of for instance pharmaceutical products.
US20110137036 SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLO[3,4-b]PYRIDINE  
The present invention relates to the stereoselective synthesis of (4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine, as well as the conversion thereof, to give Moxifloxacin. Particularly, the present...

Matches 1 - 50 out of 92 1 2 >